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https://www.readbyqxmd.com/read/28824418/effects-of-abca1-r219k-polymorphism-and-serum-lipid-profiles-on-mild-cognitive-impairment-in-type-2-diabetes-mellitus
#1
Rongrong Cai, Jing Han, Jie Sun, Rong Huang, Sai Tian, Yanjue Shen, Shaohua Wang
Background: Accumulated evidence suggests that adverse lipid changes are risk factors for type 2 diabetes mellitus (T2DM) and neurodegenerative disorders. The ATP-binding cassette A1 transporter (ABCA1) gene contributes to both lipid processing and amyloid-β formation and thus shows promise as a biological target in the pathology of mild cognitive impairment (MCI) in T2DM. Objective: This study aimed to investigate the interactions among lipids, ABCA1 R219K polymorphism, and cognitive function in T2DM. Methods: Clinical parameters, including lipids, were measured...
2017: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/28822809/inhibition-of-soluble-epoxide-hydrolase-lowers-portal-hypertension-in-cirrhotic-rats-by-ameliorating-endothelial-dysfunction-and-liver-fibrosis
#2
Wensheng Deng, Yiming Zhu, Jiayun Lin, Lei Zheng, Chihao Zhang, Meng Luo
Epoxyeicostrienoic acids (EETs) are arachidonic acid derived meditators which are catalyzed by soluble epoxide hydrolase (sEH) to less active dihydroeicostrienoics acids (DHETS). The aim of our study is to investigate the effects of sEH inhibition on hepatic and systemic hemodynamics, hepatic endothelial dysfunction, and hepatic fibrosis in CCl4 cirrhotic rats. The sEH inhibitor,trans-4-{4-[3-(4-trifluoromethoxyphenyl)-ureido]cyclohexyloxy}benzoic acid (t-TUCB) was administered to stabilize hepatic EETs by gavage at a dose of 1mg/kg/d...
August 16, 2017: Prostaglandins & Other Lipid Mediators
https://www.readbyqxmd.com/read/28822063/mind-body-therapies-in-cancer-what-is-the-latest-evidence
#3
REVIEW
Linda E Carlson, Erin Zelinski, Kirsti Toivonen, Michelle Flynn, Maryam Qureshi, Katherine-Ann Piedalue, Rachel Grant
PURPOSE OF REVIEW: Many people living with cancer use complementary therapies, and some of the most popular are mind-body therapies (MBTs), including relaxation and imagery, hypnosis, yoga, meditation, tai chi and qigong, and art therapies. The efficacy of these modalities was reviewed by assessing recent findings in the context of cancer care. RECENT FINDINGS: These therapies show efficacy in treating common cancer-related side effects, including nausea and vomiting, pain, fatigue, anxiety, depressive symptoms and improving overall quality of life...
August 18, 2017: Current Oncology Reports
https://www.readbyqxmd.com/read/28819790/contemplative-meditation-and-neuroscience-prospects-for-mental-health
#4
Denis Larrivee, Luis Echarte
Numerous studies show that personal spirituality developed through prayer positively influences mental health. Phenomenological and neuroscientific studies of mindfulness, an Eastern meditative prayer form, reveal significant health benefits now yielding important insights useful for guiding treatment of psychological disorders. By contrast, and despite its practice for millennia, Christian meditation is largely unrepresented in studies of clinical efficacy. Resemblances between mindfulness and disciplinary acts in Christian meditation taken from the ancient Greek practice of askesis suggest that Christian meditation will prove similarly beneficial; furthermore, psychological and neuroscientific studies suggest that its retention of a dialogical and transcendent praxis will additionally benefit social and existential psychotherapy...
August 17, 2017: Journal of Religion and Health
https://www.readbyqxmd.com/read/28819762/separating-the-limbs-of-yoga-limited-effects-on-stress-and-mood
#5
Evangeline A Wheeler, Antonia N Santoro, Alicia F Bembenek
Though millions of people practice yoga to reduce stress and improve their mood, it is unclear which aspect of yoga is responsible for these effects. To investigate relevant aspects, or "limbs" of yoga, participants who were novices in the practice of yoga engaged in a single yoga manipulation (i.e., poses, breath work, meditation, or listening to a lecture about yoga) for 20 min before experiencing a mild stressor. Participants' heart rate, blood pressure, mood, and anxiety level were assessed, both immediately after the yoga manipulation and after the mild stressor...
August 17, 2017: Journal of Religion and Health
https://www.readbyqxmd.com/read/28818559/-to-boldly-go-where-no-one-has-gone-before
#6
Keith W Kelley
Americans are suffering from a culture of taking pills. Six out of ten Americans utilize at least one prescription drug, and more than one in ten use five or more prescription medicines. Although this torrent of taking pills is already high, drug use in the USA has not yet crested. Prescription drugs have specific targets, but often they adversely affect other tissues and organs. In keeping with the mission of the recently named National Center for Complementary and Integrative Health (NCCIH), Brain, Behavior, and Immunity searches for the underlying cause and potential efficacy of both drug and non-drug interventions...
August 14, 2017: Brain, Behavior, and Immunity
https://www.readbyqxmd.com/read/28812504/practising-mindfulness
#7
Irene Gilsenan
What was the nature of the CPD activity, practice-related feedback and/or event and/or experience in your practice? The article examined the use of mindfulness techniques and how by learning to care for themselves, nurses can enhance the care they provide for patients. The concept of mindfulness has had widespread publicity, from meditation courses to adult colouring books, but I wanted to learn how mindfulness can be applied to nursing.
August 16, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28805552/cyclic-perimenstrual-pain-and-discomfort-and-australian-women-s-associated-use-of-complementary-and-alternative-medicine-a-longitudinal-study
#8
Carole Fisher, Louise Hickman, Jon Adams, David Sibbritt
OBJECTIVE: To examine the longitudinal change in Australian women's prevalence of cyclic perimenstrual pain and discomfort and the association between their symptoms and use of complementary and alternative medicine (CAM). METHOD: Data on endometriosis, premenstrual syndrome (PMS), irregular periods, heavy periods, and severe period pain were collected over a 7-year period from the Australian Longitudinal Study on Women's Health, for women aged 28 to 33 years in 2006, and at 3-year follow-ups...
August 14, 2017: Journal of Women's Health
https://www.readbyqxmd.com/read/28804621/development-of-gene-polymorphisms-in-meditators-of-nonalcoholic-fatty-liver-disease
#9
Chun Wang, Jianping Gong, Hao Wu
Nonalcoholic fatty liver disease (NAFLD) is the most prevalent liver disease worldwide, the morbidity of which closely correlates with diversity of ethnicity, minority, family and location. Its histology spans from simple steatosis, to nonalcoholic steatohepatitis, which ultimately results in fibrosis, cirrhosis and hepatocellular carcinoma. The accelerating prevalence of NAFLD is due to an incremental incidence of metabolic syndrome that is distinguished by dyslipidemia, glucose impairment, obesity, excessive oxidative stress and adipocytokine impairment...
August 2017: Biomedical Reports
https://www.readbyqxmd.com/read/28803082/addressing-patient-emotional-and-existential-needs-during-serious-illness-results-of-the-outlook-randomized-controlled-trial
#10
Karen E Steinhauser, Stewart Alexander, Maren K Olsen, Karen M Stechuchak, Jennifer Zervakis, Natalie Ammarell, Ira Byock, James A Tulsky
CONTEXT: Few interventions exist to address patients' existential needs. OBJECTIVE: Determine whether an intervention to address seriously-ill patients' existential concerns improves preparation, completion (elements of quality-of-life at end-of-life) and reduces anxiety and depression. METHODS: A randomized control trial comparing: 1)Outlook intervention, 2)Relaxation meditation (RM); and 3)Usual care (UC). Measures included: primary - quality-of-life (QUAL-E) and secondary - FACT-G, anxiety (POMS), depression (CES-D), and spiritual well-being (FACIT-sp)...
August 9, 2017: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/28802468/integrative-medicine-for-insomnia
#11
REVIEW
Eric S Zhou, Paula Gardiner, Suzanne M Bertisch
Difficulty initiating and/or maintaining sleep is a common issue. Patients experiencing insomnia symptoms frequently self-treat their symptoms with sleep medications. However, there remains concern regarding the short- and long-term health impacts of sleep medications. This article discusses the evidence supporting integrative approaches to insomnia treatment, including cognitive-behavioral therapy and mind-body therapies (mindfulness meditation, yoga, tai chi), as well as emerging data for use of other less well supported approaches (dietary supplements, acupuncture)...
September 2017: Medical Clinics of North America
https://www.readbyqxmd.com/read/28802467/complementary-therapies-for-mental-health-disorders
#12
REVIEW
Gary N Asher, Jonathan Gerkin, Bradley N Gaynes
Approximately 18% of the US adult population has a mental illness, yet only 13% with mental illness receive any treatment. Although pharmacotherapy and psychotherapy are the mainstays of treatment, treatment discontinuation and failure are common. Skepticism toward such treatments has fueled interest in and use of complementary therapies, such as acupuncture, meditation, and natural products. Many medical providers are unaware of the use of these therapies by their patients, and knowledge of the evidence base for these therapies is often lacking...
September 2017: Medical Clinics of North America
https://www.readbyqxmd.com/read/28798908/characteristics-of-yoga-practitioners-motivators-and-yoga-techniques-of-choice-a-cross-sectional-study
#13
Shirley Telles, Sachin Kumar Sharma, Nilkamal Singh, Acharya Balkrishna
BACKGROUND: The characteristics of yoga practitioners and factors motivating people to practice yoga have been studied in the US and in Australia. This study aimed to determine the characteristics of yoga users in India, the factors that motivate them to practice yoga, and the yoga techniques of choice. MATERIALS AND METHODS: The study was a one-time, cross-sectional survey based on convenience sampling. Inclusion criteria were (a) a minimum of 1 week experience of yoga and (b) at least 10 years of age...
2017: Frontiers in Public Health
https://www.readbyqxmd.com/read/28795775/interventions-to-reduce-perceived-stress-among-graduate-students-a-systematic-review-with-implications-for-evidence-based-practice
#14
Susan B Stillwell, Amber L Vermeesch, Jane G Scott
BACKGROUND: Stress is a part of daily life for graduate students, including graduate nursing students. Contemporary graduate nursing students are facing unprecedented challenges to meet rigorous academic standards as they prepare for their advanced professional role to meet the demands of the nation's complex and ever-changing healthcare system. Empowering graduate nursing students to ease their perceived stress and minimize undesirable health effects may benefit their capacity to adapt and successfully manage perceived stress in their future healthcare role...
August 10, 2017: Worldviews on Evidence-based Nursing
https://www.readbyqxmd.com/read/28795335/encouraging-mindfulness-in-medical-house-staff-via-smartphone-app-a-pilot-study
#15
Louise Wen, Timothy E Sweeney, Lindsay Welton, Mickey Trockel, Laurence Katznelson
BACKGROUND: Stress and burnout are increasingly recognized as urgent issues among resident physicians, especially given the concerning implications of burnout on physician well-being and patient care outcomes. OBJECTIVE: The authors assessed how a mindfulness and meditation practice among residents, supported via a self-guided, smartphone-based mindfulness app, affects wellness as measured by prevalidated surveys. METHODS: Residents in the departments of general surgery, anesthesia, and obstetrics and gynecology were recruited for participation in this survey-based, four-week, single-arm study...
August 9, 2017: Academic Psychiatry
https://www.readbyqxmd.com/read/28789681/study-protocol-on-comparative-effectiveness-of-mindfulness-meditation-and-qigong-on-psychophysiological-outcomes-for-patients-with-colorectal-cancer-a-randomized-controlled-trial
#16
Rainbow T H Ho, Adrian H Y Wan, Jessie S M Chan, S M Ng, K F Chung, Cecilia L W Chan
BACKGROUND: Colorectal cancer imposes threats to patients' well-being. Although most physical symptoms can be managed by medication, psychosocial stressors may complicate survival and hamper quality of life. Mindfulness and Qigong, two kinds of mind-body exercise rooted in Eastern health philosophy, has been found effective in symptoms management, improving mental health, and reducing stress. With these potential benefits, a randomized controlled trial (RCT) is planned to investigate the comparative effectiveness of mindfulness and Baduanjin intervention on the bio-psychosocial wellbeing of people with colorectal cancer...
August 8, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28776205/psychological-factors-that-link-socioeconomic-status-to-depression-anxiety-in-patients-with-systemic-lupus-erythematosus
#17
Desiree R Azizoddin, Geraldine Zamora-Racaza, Sarah R Ormseth, Lekeisha A Sumner, Chelsie Cost, Julia R Ayeroff, Michael H Weisman, Perry M Nicassio
Our analyses examined whether reserve capacity factors would explain the relationship between socioeconomic status (SES) and symptoms of depression/anxiety in patients with systemic lupus erythematosus (SLE). We assessed disease activity, depression/anxiety symptoms, and intrapersonal and interpersonal reserve capacity measures in 128 patients with SLE. Multiple meditational analyses revealed that intrapersonal and interpersonal psychosocial aspects of reserve capacity fully mediated the relationship between SES and depression/anxiety...
August 3, 2017: Journal of Clinical Psychology in Medical Settings
https://www.readbyqxmd.com/read/28766027/telephone-delivered-mindfulness-training-for-people-living-with-hiv-a-qualitative-360%C3%A2-inquiry
#18
Rochelle K Rosen, Larissa A McGarrity, Elena Salmoirago-Blotcher, Carla Rich, Aadia Rana, Michael P Carey
For people living with HIV and AIDS (PLWHA), life stress often undermines quality of life and interferes with medical care. Mindfulness training (MT) may help PLWHA to manage stress. Because standard MT protocols can be burdensome, we explored telephone delivery as a potentially more feasible approach. We used an innovative 360° qualitative inquiry to seek input regarding telephone-delivery of MT for PLWHA in advance of a planned intervention trial. We also sought input on a time- and attention-matched control...
August 1, 2017: AIDS and Behavior
https://www.readbyqxmd.com/read/28765006/rationale-design-and-implementation-of-a-clinical-trial-of-a-mindfulness-based-relapse-prevention-protocol-for-the-treatment-of-women-with-comorbid-post-traumatic-stress-disorder-and-substance-use-disorder
#19
Caroline Vrana, Therese Killeen, Victoria Brant, Jana Mastrogiovanni, Nathaniel L Baker
Comorbid post-traumatic stress disorder (PTSD) and substance use disorders (SUD) commonly co-occur and is associated with a more complex clinical presentation with poorer clinical outcomes when compared with either disorder alone, and untreated PTSD can predict relapse to substance abuse. A number of integrated treatment approaches addressing symptoms of both PTSD and SUD concurrently demonstrate that both disorders can safely and effectively be treated concurrently. However, attrition and SUD relapse rates remain high and there is need to further develop new treatment approaches...
July 29, 2017: Contemporary Clinical Trials
https://www.readbyqxmd.com/read/28763262/guidelines-for-teaching-yoga-to-women-with-breast-cancer-related-lymphoedema-an-evidence-based-approach
#20
Annette Loudon, Tony Barnett, Andrew D Williams, Denis Visentin, Maarten A Immink, Neil Piller
Breast cancer-related lymphoedema (BCRL) is a chronic condition that requires lifelong management to prevent the condition worsening and to reduce the threat of infection. Women are affected in all domains of their life. As a holistic practice, yoga may be of benefit by reducing both the physical and psychosocial effects of lymphoedema. Women with BCRL are attending yoga classes in increasing numbers, so it is essential that yoga be based on principles that ensure lymphoedema is controlled and not exacerbated...
August 1, 2017: International Journal of Yoga Therapy
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