keyword
https://read.qxmd.com/read/34184984/management-of-type-2-diabetes-in-people-with-renal-impairment
#21
Alice Yy Cheng, Lance Sloan, John Anderson
Diabetes is a progressive disease associated with micro- and macrovascular complications. Type 2 diabetes (T2D) is the leading contributor to chronic kidney disease (CKD) worldwide, which itself is associated with an increased burden of cardiovascular disease, increased risk of hypoglycemia, and increased risk of death beyond that caused by diabetes alone. In this video series available on The Journal of Family Practice website, the authors discuss how CKD in people with T2D is defined, potential consequences of CKD in this patient population, and how those with CKD and T2D should be identified, monitored, and treated...
May 2021: Journal of Family Practice
https://read.qxmd.com/read/33560245/a-web-based-self-management-support-prototype-for-adults-with-chronic-kidney-disease-my-kidneys-my-health-co-design-and-usability-testing
#22
JOURNAL ARTICLE
Maoliosa Donald, Heather Beanlands, Sharon E Straus, Michelle Smekal, Sarah Gil, Meghan J Elliott, Gwen Herrington, Lori Harwood, Blair Waldvogel, Maria Delgado, Dwight Sparkes, Allison Tong, Allan Grill, Marta Novak, Matthew Thomas James, K Scott Brimble, Susan Samuel, Karen Tu, Janine Farragher, Brenda R Hemmelgarn
BACKGROUND: Supporting patients to self-manage their chronic kidney disease (CKD) has been identified as a research priority by patients with CKD and those who care for them. Self-management has been shown to slow CKD progression and improve the quality of life of individuals living with the disease. Previous work has identified a need for a person-centered, theory-informed, web-based tool for CKD self-management that can be individualized to a patient's unique situation, priorities, and preferences...
February 9, 2021: JMIR Formative Research
https://read.qxmd.com/read/33522934/use-and-preferences-regarding-internet-based-health-care-delivery-in-patients-with-chronic-kidney-disease
#23
JOURNAL ARTICLE
Lena Schiffer, Raoul Gertges, Mariel Nöhre, Elisabeth Schieffer, Uwe Tegtbur, Lars Pape, Martina de Zwaan, Mario Schiffer
BACKGROUND AND OBJECTIVES: Internet-based technologies play an increasingly important role in the management and outcome of patients with chronic kidney disease (CKD). The healthcare system is currently flooded with digital innovations and internet-based technologies as a consequence of the coronavirus disease 2019 (COVID-19) pandemic. However, information about the attitude of German CKD-patients with access to online tools towards the use of remote, internet-based interactions such as video conferencing, email, electronic medical records and apps in general and for health issues in particular, are missing...
February 1, 2021: BMC Medical Informatics and Decision Making
https://read.qxmd.com/read/33184239/customized-versus-conventional-video-counseling-for-peritoneal-dialysis-decision-making-in-patients-with-stage-5-chronic-kidney-disease-under-a-pd-first-policy-a-randomized-controlled-study
#24
JOURNAL ARTICLE
Watanyu Parapiboon, Wannapat Pitsawong, Laddaporn Wongluechai, Kanin Thammavaranucupt, Lalana Raegasint
BACKGROUND: Indecision regarding the start of peritoneal dialysis (PD) is a challenging problem in chronic kidney disease (CKD) stage 5 patients who receive conventional video counseling. This study aimed to evaluate the effect of video counseling customized to the local context versus conventional video counseling on PD decision-making in CKD stage 5 patients under PD-first policy. METHODS: We enrolled 120 patients with stage 5 CKD in Thailand who initiate PD between May 2016 to January 2017 in a randomized, open-label, controlled study...
December 31, 2020: Kidney Research and Clinical Practice
https://read.qxmd.com/read/33064902/the-presence-of-diabetes-mellitus-further-impairs-structural-and-functional-capillary-density-in-patients-with-chronic-kidney-disease
#25
JOURNAL ARTICLE
Maria Schoina, Charalampos Loutradis, Marieta Theodorakopoulou, Theodoros Dimitroulas, Eva Triantafillidou, Michael Doumas, Asterios Karagiannis, Alexandros Garyfallos, Aikaterini Papagianni, Pantelis Sarafidis
OBJECTIVE: Endothelial dysfunction has been associated with increased cardiovascular events and overall mortality. Microvascular damage is prevalent both in diabetes mellitus (DM) and chronic kidney disease (CKD). Our aim was to compare microcirculatory function parameters in diabetic and non-diabetic CKD patients via nailfold video-capillaroscopy. METHODS: We included 48 diabetic and 48 non-diabetic adult CKD patients. All participants underwent nailfold video-capillaroscopy, during which capillary density was measured at normal conditions (baseline), after a 4-minute arterial occlusion (postocclusive reactive hyperemia), and at the end of a 2-minute venous occlusion (congestion phase)...
February 2021: Microcirculation: the Official Journal of the Microcirculatory Society, Inc
https://read.qxmd.com/read/32888215/supporting-patients-to-be-involved-in-decisions-about-their-health-and-care-development-of-a-best-practice-health-literacy-app-for-australian-adults-living-with-chronic-kidney-disease
#26
JOURNAL ARTICLE
Danielle Marie Muscat, Kelly Lambert, Heather Shepherd, Kirsten J McCaffery, Stephanie Zwi, Na Liu, Kamal Sud, John Saunders, Emma O'Lone, Jinman Kim, Aphra Robbins, Angela C Webster
ISSUE ADDRESSED: Inadequate health literacy is common in those with chronic kidney disease (CKD), especially among culturally and linguistically diverse groups. Patient information for people with CKD, including those with kidney failure requiring dialysis, is often written beyond their literacy level, and many CKD-related apps are not accurate or evidence based. These represent important barriers to health care decision-making and equity in access to health care. METHODS: We developed a cross-platform application (the "SUCCESS app") to support Australian adults with kidney failure requiring dialysis to actively participate in self-management and decision-making...
February 2021: Health Promotion Journal of Australia
https://read.qxmd.com/read/32791499/use-of-a-supportive-kidney-care-video-decision-aid-in-older-patients-a-randomized-controlled-trial
#27
RANDOMIZED CONTROLLED TRIAL
Nwamaka D Eneanya, Shananssa G Percy, Taylor L Stallings, Wei Wang, David J R Steele, Michael J Germain, Jane O Schell, Michael K Paasche-Orlow, Angelo E Volandes
BACKGROUND: There are few studies of patient-facing decision aids that include supportive kidney care as an option. We tested the efficacy of a video decision aid on knowledge of supportive kidney care among older patients with advanced CKD. METHODS: Participants (age ≥ 65 years with advanced CKD) were randomized to receive verbal or video education. Primary outcome was knowledge of supportive kidney care (score range 0-3). Secondary outcomes included preference for supportive kidney care, and satisfaction and acceptability of the video...
2020: American Journal of Nephrology
https://read.qxmd.com/read/32728149/microcirculatory-function-deteriorates-with-advancing-stages-of-chronic-kidney-disease-independently-of-arterial-stiffness-and-atherosclerosis
#28
JOURNAL ARTICLE
Maria Schoina, Charalampos Loutradis, Evangelos Memmos, Theodoros Dimitroulas, Eleni Pagkopoulou, Michael Doumas, Asterios Karagiannis, Alexandros Garyfallos, Aikaterini Papagianni, Pantelis Sarafidis
Cardiovascular disease is the main cause of mortality in chronic kidney disease (CKD). Endothelial dysfunction and capillary rarefaction are established cardiovascular risk factors. Nailfold video capillaroscopy provides a thorough assessment of capillary density and functional reserve. This study aimed to examine possible differences in structural and functional capillary density in CKD stages 2-4 with nailfold video capillaroscopy. Ninety-six CKD patients, divided into four equally sized groups according to CKD stage (2, 3a, 3b, 4), underwent nailfold video capillaroscopy, during which capillary density was measured at baseline, after 4-min arterial occlusion and after 2-min venous occlusion...
February 2021: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://read.qxmd.com/read/32450899/blocking-connexin-43-mediated-hemichannel-activity-protects-against-early-tubular-injury-in-experimental-chronic-kidney-disease
#29
JOURNAL ARTICLE
Gareth W Price, Christos E Chadjichristos, Panagiotis Kavvadas, Sydney C W Tang, Wai Han Yiu, Colin R Green, Joe A Potter, Eleftherios Siamantouras, Paul E Squires, Claire E Hills
BACKGROUND: Tubulointerstitial fibrosis represents the key underlying pathology of Chronic Kidney Disease (CKD), yet treatment options remain limited. In this study, we investigated the role of connexin43 (Cx43) hemichannel-mediated adenosine triphosphate (ATP) release in purinergic-mediated disassembly of adherens and tight junction complexes in early tubular injury. METHODS: Human primary proximal tubule epithelial cells (hPTECs) and clonal tubular epithelial cells (HK2) were treated with Transforming Growth Factor Beta1 (TGF-β1) ± apyrase, or ATPγS for 48 h...
May 25, 2020: Cell Communication and Signaling: CCS
https://read.qxmd.com/read/32238045/recommendations-for-systematizing-transplant-education-within-a-care-delivery-system-for-patients-with-chronic-kidney-disease-stages-3-to-5
#30
JOURNAL ARTICLE
Amy D Waterman, Amanda Faye Lipsey, Omesh N Ranasinghe, Emily H Wood, Crystal Anderson, Carla Bozzolo, Shayna L Henry, Bhanuja Dub, Brian Mittman
CONTEXT: Early tailored transplant education could help patients make informed transplant choices. OBJECTIVE: We interviewed 40 patients with chronic kidney disease (CKD) stages 3 to 5, 13 support persons, and 10 providers at Kaiser Permanente Southern California to understand: (1) barriers to transplant education and (2) transplant educational preferences and recommendations based on CKD stage and primary language spoken. DESIGN: A grounded theory analysis identified central themes related to transplant education barriers, preferences, and recommendations...
June 2020: Progress in Transplantation
https://read.qxmd.com/read/31610269/development-and-validation-of-a-uremic-pruritus-treatment-algorithm-and-patient-information-toolkit-in-patients-with-chronic-kidney-disease-and-end-stage-kidney-disease
#31
JOURNAL ARTICLE
Jessica Ragazzo, Annemarie Cesta, S Vanita Jassal, Nicholas Chiang, Marisa Battistella
CONTEXT: Uremic pruritus (UP) affects up to half of all patients with kidney disease and has been independently associated with poor patient outcomes. UP is a challenging symptom for clinicians to manage as there are no validated guidelines for its treatment. OBJECTIVES: The study aimed to develop and validate an algorithm and patient information toolkit for the treatment of UP in patients with kidney disease. METHODS: The study involved a literature search and development of an initial draft algorithm, followed by content and face validation of this algorithm...
February 2020: Journal of Pain and Symptom Management
https://read.qxmd.com/read/31438420/chronic-kidney-disease-and-the-use-of-social-media-as-strategy-for-health-education-in-brazil
#32
JOURNAL ARTICLE
Juliana Gomes Ramalho de Oliveira, Marjan Askari, Marília Girão Nobre Fahd, Gabriel Araújo Pereira, Aglalberto Lourenço da Silva, José Eurico Vasconcelos Filho, Maria Helena de Agrela Gonçalves Jardim, Geraldo Bezerra da Silva Junior
Chronic kidney disease (CKD) is a Public Health problem worldwide. Treatment in complex and depends on patient education to achieve adequate adherence. We describe in this paper novel strategies for patients' education based on internet (youtube and instagram), through videos, images and texts information directed for patients in a project developed in Brazil.
August 21, 2019: Studies in Health Technology and Informatics
https://read.qxmd.com/read/30693601/-knowledge-is-power-a-framework-for-partnering-with-consumers-in-developing-and-delivering-a-scientific-meeting-in-nephrology
#33
Emily Duncanson, Kathryn Dansie, Talia Gutman, Allison Tong, Martin Howell, Shilpanjali Jesudason, Donna Reidlinger, Amber Williamson, Nicole Scholes-Robertson, Lisa Murphy, Carmel M Hawley, Jonathan C Craig, David W Johnson, Stephen McDonald
Involving consumers (patients, carers and family members) across all stages of research is gaining momentum in the nephrology community. Scientific meetings present a partnership opportunity with consumers for dissemination of research findings. The Better Evidence and Translation in Chronic Kidney Disease (BEAT-CKD) research collaboration, in partnership with Kidney Health Australia, convened two consumer sessions at the 54th Australian and New Zealand Society of Nephrology Annual Scientific Meeting held in September 2018...
May 2020: Nephrology
https://read.qxmd.com/read/30057772/explore-transplant-ontario-adapting-the-explore-transplant-education-program-to-facilitate-informed-decision-making-about-kidney-transplantation
#34
JOURNAL ARTICLE
Istvan Mucsi, Marta Novak, Deanna Toews, Amy Waterman
PURPOSE: In this article, we describe a province-wide collaborative project in which we adapted the Explore Transplant (ET) education program for use in Ontario, Canada, to develop Explore Transplant Ontario (ETO). Kidney transplantation (KT), especially living donor kidney transplantation (LDKT), is the best treatment for many patients with end-stage kidney disease (ESKD), with the best patient survival and quality of life and also reduced health care costs. Yet KT and LDKT are underutilized both internationally and in Canada...
2018: Canadian Journal of Kidney Health and Disease
https://read.qxmd.com/read/29161692/association-between-extreme-values-of-markers-of-chronic-kidney-disease-mineral-and-bone-disorder-and-5-year-mortality-among-prevalent-hemodialysis-patients
#35
JOURNAL ARTICLE
Jin-Gang Zhu, Jin-Bor Chen, Ben-Chung Cheng, Chih-Hsiung Lee, Gang Long, Yu-Shu Chien
BACKGROUND/AIMS: We examined the association between markers of chronic kidney disease - mineral and bone disorder (CKD-MBD) and mortality in hemodialysis (HD) patients. METHODS: We retrospectively reviewed the association between markers of CKD-MBD and mortality in 1,126 HD patients from 2009 to 2013 with baseline (B), time-average (TA), and time-dependent (TD) Cox regression models. RESULTS: Hypercalcemia (10.9-11.9 mg/dL) indicated an increased risk of all-cause mortality (TA: hazard ratio [HR] 3...
2018: Blood Purification
https://read.qxmd.com/read/29100941/impact-of-clinical-pharmacist-services-delivered-via-telemedicine-in-the-outpatient-or-ambulatory-care-setting-a-systematic-review
#36
REVIEW
Joshua D Niznik, Harvey He, Sandra L Kane-Gill
BACKGROUND: Utilization of telemedicine allows pharmacists to extend the reach of clinical interventions, connecting them with patients and providers, but the overall impact of these services is under-studied. OBJECTIVE: Identify the impact of clinical pharmacist telemedicine interventions on clinical outcomes, subsequently defined as clinical disease management, patient self-management, and adherence, in outpatient or ambulatory settings. METHODS: A literature search was conducted from database inception through May 2016 in Medline, SCOPUS, and EMBASE...
August 2018: Research in Social & Administrative Pharmacy: RSAP
https://read.qxmd.com/read/28490898/education-and-screening-for-chronic-kidney-disease-in-indian-youth-pilot-program-results
#37
JOURNAL ARTICLE
Panduranga S Rao, Julie A Wright Nunes, Brenda W Gillespie, Rachel L Perlman, Rajan Ravichandran
BACKGROUND: There is a paucity of information on kidney education and screening programs in Indian youth. METHODS: Participants (n=2,158) from Chennai colleges were educated about the kidneys and chronic kidney disease (CKD) and screened in a pilot program from April to May 2013. This entailed: 1) a presentation and educational video and 2) an on-site assessment of weight, blood pressure, and demographic information. Urinalysis (UA) kits were distributed and returned in ≤48 hours...
2017: International Journal of Nephrology and Renovascular Disease
https://read.qxmd.com/read/28132720/kidney-disease-population-health-management-in-the-era-of-accountable-care-a-conceptual-framework-for-optimizing-care-across-the-ckd-spectrum
#38
JOURNAL ARTICLE
Mallika L Mendu, Sushrut S Waikar, Sandhya K Rao
Since its passage in 2010, the Affordable Care Act has led to the creation of numerous accountable care organizations that face the challenge of transforming the traditional care delivery model to provide more patient-centered, high-quality, and low-cost care. Complex patients, including those with chronic kidney disease (CKD), present the most challenges and opportunities. CKD is a condition with significant morbidity, mortality, and cost and thought to be partly secondary to known gaps in care delivery. Successful population management for CKD requires consideration of the needs of patients at all phases of the disease...
July 2017: American Journal of Kidney Diseases
https://read.qxmd.com/read/28114144/hepatitis-c-treatment-in-chronic-kidney-disease-patients-the-kidney-disease-improving-global-outcomes-perspective
#39
REVIEW
Michel Jadoul, Paul Martin
BACKGROUND: Hepatitis C virus (HCV) infection is a very common infection found among hemodialysis (HD) and kidney transplant patients. It is associated with substantial morbidity and mortality. Direct-acting antiviral agents (DAAs) have much better efficacy (sustained viral response (SVR)) and tolerance than interferon-based regimens. Very recent studies extend this breakthrough finding to chronic kidney disease (CKD) populations. SUMMARY: CKD patients with an estimated glomerular filtration rate (eGFR) >30 ml/min/1...
2017: Blood Purification
https://read.qxmd.com/read/27694753/the-influence-of-hemodialysis-on-t-regulatory-cells-a-meta-analysis-and-systematic-review
#40
COMMENT
Carlotta Caprara, Gilbert R Kinsey, Valentina Corradi, Wenjun Xin, Jennie Z Ma, Elisa Scalzotto, Francesca K Martino, Mark D Okusa, Federico Nalesso, Fiorenza Ferrari, Mitchell Rosner, Claudio Ronco
AIMS: The study aimed to determine whether the available literature supports a positive or negative influence of dialysis on regulatory T-cells (Tregs). METHODS: We performed a systematic search and a meta-analysis. Mean differences in Tregs number of chronic kidney disease stages G5 on dialysis patients (CKD G5D) and healthy controls (HCs) were compared. Random effects model was applied. The software used was general package for meta-analysis (version 4.3-0, depends R (≥2...
2016: Blood Purification
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