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https://www.readbyqxmd.com/read/29779276/-fabrication-and-accuracy-research-on-3d-printing-dental-model-based-on-cone-beam-computed-tomography-digital-modeling
#1
Hui-Rong Zhang, Le-Feng Yin, Yan-Li Liu, Li-Yi Yan, Ning Wang, Gang Liu, Xiao-Li An, Bin Liu
OBJECTIVE: The aim of this study is to build a digital dental model with cone beam computed tomography (CBCT), to fabricate a virtual model via 3D printing, and to determine the accuracy of 3D printing dental model by comparing the result with a traditional dental cast. METHODS: CBCT of orthodontic patients was obtained to build a digital dental model by using Mimics 10.01 and Geomagic studio software. The 3D virtual models were fabricated via fused deposition modeling technique (FDM)...
April 1, 2018: Hua Xi Kou Qiang Yi Xue za Zhi, Huaxi Kouqiang Yixue Zazhi, West China Journal of Stomatology
https://www.readbyqxmd.com/read/29779201/clinical-acceptability-of-trimetazidine-modified-release-80-mg-once-daily-versus-trimetazidine-modified-release-35-mg-twice-daily-in-stable-angina-pectoris
#2
Yuri M Pozdnyakov
INTRODUCTION: Trimetazidine (TMZ) is an anti-ischemic metabolic agent that has been shown to be efficacious in angina treatment, both in monotherapy and in combination. A new formulation of TMZ modified-release (MR) 80 mg was developed, which is to be taken once daily (od), instead of twice daily (bid) for the currently available TMZ MR 35 mg, with the aim of simplifying the medication regimen. METHODS: The present study was an international, multicenter, randomized, double-blind, parallel-group phase III study with a 12-week treatment period...
May 19, 2018: Cardiology and Therapy
https://www.readbyqxmd.com/read/29779145/comprehensive-genetic-testing-for-female-and-male-infertility-using-next-generation-sequencing
#3
Bonny Patel, Sasha Parets, Matthew Akana, Gregory Kellogg, Michael Jansen, Chihyu Chang, Ying Cai, Rebecca Fox, Mohammad Niknazar, Roman Shraga, Colby Hunter, Andrew Pollock, Robert Wisotzkey, Malgorzata Jaremko, Alex Bisignano, Oscar Puig
PURPOSE: To develop a comprehensive genetic test for female and male infertility in support of medical decisions during assisted reproductive technology (ART) protocols. METHODS: We developed a next-generation sequencing (NGS) gene panel consisting of 87 genes including promoters, 5' and 3' untranslated regions, exons, and selected introns. In addition, sex chromosome aneuploidies and Y chromosome microdeletions were analyzed concomitantly using the same panel. RESULTS: The NGS panel was analytically validated by retrospective analysis of 118 genomic DNA samples with known variants in loci representative of female and male infertility...
May 19, 2018: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/29779107/stabilization-of-butyrylcholinesterase-by-the-entrapment-into-the-natural-polymer-based-gels
#4
V I Lonshakova-Mukina, E N Esimbekova, V A Kratasyuk
A new method for obtaining stable butyrylcholinesterase (BuChE) samples based on the enzyme immobilization in starch and gelatin gels followed by drying is proposed. Coimmobilization of BuChE with the thiol group indicator 5,5'-dithiobis(2-nitrobenzoic) acid did not reduce the activity of BuChE, which allowed us to simplify the procedure and reduce the time of analysis of organophosphorus pesticides. The resulting immobilized samples retained activity for at least 300 days. BuChE samples based on the starch gel showed a greater sensitivity in the determination of pesticides as compared to the samples based on the gelatin gel...
March 2018: Doklady. Biochemistry and Biophysics
https://www.readbyqxmd.com/read/29778987/effect-of-ethanol-dissolved-rhodamine-b-marker-on-mechanical-properties-of-non-simplified-adhesives
#5
Camila Moreira Machado, Odair Bim Júnior, Marina Ciccone Giacomini, Márcia Sirlene Zardin Graeff, Fernanda Cristina Pimentel Garcia, Daniela Rios, Heitor Marques Honório, Linda Wang
OBJECTIVES: Rhodamine B (RB) is commonly used to evaluate dental polymers, including dental bonding systems (DBS). For reliability assessments, its effect should not only allow visualization of the dentin-polymer interface but also must not interfere with the bonding of the DBS to dentin as measured by the microtensile bond strength and hardness tests. MATERIAL AND METHODS: Flat human dentin surfaces were prepared and randomly distributed (n = 10) into six groups: Adper Scotchbond Multi-Purpose (MP) or Clearfil SE Bond (SE) in concentrations of none/control, 0...
May 17, 2018: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/29778755/development-and-acceptability-assessment-of-a-self-management-intervention-to-prevent-acute-to-chronic-pain-transition-after-major-lower-extremity-trauma
#6
Mélanie Bérubé, Céline Gélinas, Géraldine Martorella, Nancy Feeley, José Côté, George-Yves Laflamme, Dominique M Rouleau, Manon Choinière
Transition from acute to chronic pain often occurs after major lower extremity trauma. Chronic pain has been found to negatively affect daily functioning, including the capacity to work and quality of life. Empirical data and an acceptability assessment were used to develop a self-management intervention aimed at preventing acute to chronic pain transition after major lower extremity trauma (i.e., iPACT-E-Trauma). Evidence from previous studies on preventive self-management interventions, combined with a biopsychosocial conceptual framework and clinical knowledge, helped define the key features of the preliminary version...
May 16, 2018: Pain Management Nursing: Official Journal of the American Society of Pain Management Nurses
https://www.readbyqxmd.com/read/29778034/early-discharge-of-patients-with-pulmonary-embolism-in-daily-clinical-practice-a-prospective-observational-study-comparing-clinical-gestalt-and-clinical-rules
#7
Simone Vanni, Cecilia Becattini, Peiman Nazerian, Carlo Bova, Valerio Teodoro Stefanone, Ludovica Anna Cimini, Gabriele Viviani, Cosimo Caviglioli, Michela Sanna, Giuseppe Pepe, Stefano Grifoni
OBJECTIVES: To estimate the efficiency and safety of clinicians' gestalt in the identification of patients with pulmonary embolism (PE) candidates for early discharge and to compare the efficiency and safety of clinical gestalt with that of the Pulmonary Embolism Severity Index (PESI), the simplified PESI (sPESI) and the Hestia criteria (HC). METHODS: Consecutive adult patients presenting to the emergency department of four Italian hospitals with confirmed diagnosis of PE were included...
May 8, 2018: Thrombosis Research
https://www.readbyqxmd.com/read/29777534/is-it-necessary-to-have-a-dentist-within-an-intensive-care-unit-team-report-of-a-randomised-clinical-trial
#8
Wanessa Teixeira Bellissimo-Rodrigues, Mayra Gonçalves Menegueti, Gilberto Gambero Gaspar, Hayala Cristina Cavenague de Souza, Maria Auxiliadora-Martins, Anibal Basile-Filho, Roberto Martinez, Fernando Bellissimo-Rodrigues
OBJECTIVE: To evaluate the effectiveness of dental treatment in improving oral health in critical patients. METHODS: This randomised clinical trial was conducted in a general intensive care unit (ICU) at a tertiary care public facility from 1 January 2011 to 8 August 2013. Data from 254 adult patients staying in the ICU for 48 hours or more were analysed. The experimental group (n = 127) had access to dental treatment provided by a dentist four to five times a week, in addition to routine oral hygiene, whereas the control group (n = 127) had access only to routine oral hygiene, including topical application of chlorhexidine, provided by the ICU nursing staff...
May 18, 2018: International Dental Journal
https://www.readbyqxmd.com/read/29776855/incidence-and-risk-factors-of-kinesiophobia-after-total-knee-arthroplasty-in-zhengzhou-china-a-cross-sectional-study
#9
Libai Cai, Yanjin Liu, Huiping Xu, Qiulu Xu, Yanyan Wang, Peihua Lyu
BACKGROUND: The incidence of and risk factors for kinesiophobia after total knee arthroplasty (TKA) have not been well characterized in the literature. Thus, the aim of this study was to investigate the incidence of postoperative kinesiophobia among patients undergoing TKA and to identify the associated risk factors. METHODS: The simplified Chinese version of the Tampa Scale for Kinesiophobia, Knee Self-Efficacy Scale, Numerical Rating Scale, Simplified Coping Style Questionnaire, and Social Support Rating Scale were used to measure kinesiophobia, self-efficacy, pain intensity, coping styles and social support, respectively...
April 23, 2018: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29776139/transition-between-inverse-and-direct-energy-cascades-in-multiscale-optical-turbulence
#10
V M Malkin, N J Fisch
Multiscale turbulence naturally develops and plays an important role in many fluid, gas, and plasma phenomena. Statistical models of multiscale turbulence usually employ Kolmogorov hypotheses of spectral locality of interactions (meaning that interactions primarily occur between pulsations of comparable scales) and scale-invariance of turbulent pulsations. However, optical turbulence described by the nonlinear Schrodinger equation exhibits breaking of both the Kolmogorov locality and scale-invariance. A weaker form of spectral locality that holds for multi-scale optical turbulence enables a derivation of simplified evolution equations that reduce the problem to a single scale modeling...
March 2018: Physical Review. E
https://www.readbyqxmd.com/read/29776084/deep-neural-networks-for-direct-featureless-learning-through-observation-the-case-of-two-dimensional-spin-models
#11
Kyle Mills, Isaac Tamblyn
We demonstrate the capability of a convolutional deep neural network in predicting the nearest-neighbor energy of the 4×4 Ising model. Using its success at this task, we motivate the study of the larger 8×8 Ising model, showing that the deep neural network can learn the nearest-neighbor Ising Hamiltonian after only seeing a vanishingly small fraction of configuration space. Additionally, we show that the neural network has learned both the energy and magnetization operators with sufficient accuracy to replicate the low-temperature Ising phase transition...
March 2018: Physical Review. E
https://www.readbyqxmd.com/read/29776007/development-and-psychometric-evaluation-of-the-swedish-propensity-to-achieve-healthy-lifestyle-scale-in-patients-with-hypertension
#12
Anders Broström, A H Pakpour, Martin Ulander, Per Nilsen
PURPOSE: To develop and validate a Swedish questionnaire to measure propensity for behaviour change regarding food habits, physical activity and weight reduction in patients with hypertension. DESIGN: Cross-sectional design. METHODS: A total of 270 consecutive patients with hypertension diagnosed at 4 primary care centres in Sweden were included. The 6-item Swedish version of the Propensity to Achieve Healthy Lifestyle Scale (PAHLS) was developed to measure propensity for behaviour change regarding food habits, physical activity and weight reduction...
May 18, 2018: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/29775951/retinal-blood-vessel-segmentation-using-fully-convolutional-network-with-transfer-learning
#13
Zhexin Jiang, Hao Zhang, Yi Wang, Seok-Bum Ko
Since the retinal blood vessel has been acknowledged as an indispensable element in both ophthalmological and cardiovascular disease diagnosis, the accurate segmentation of the retinal vessel tree has become the prerequisite step for automated or computer-aided diagnosis systems. In this paper, a supervised method is presented based on a pre-trained fully convolutional network through transfer learning. This proposed method has simplified the typical retinal vessel segmentation problem from full-size image segmentation to regional vessel element recognition and result merging...
April 26, 2018: Computerized Medical Imaging and Graphics: the Official Journal of the Computerized Medical Imaging Society
https://www.readbyqxmd.com/read/29775913/mobile-phone-based-evaluation-of-latent-tuberculosis-infection-proof-of-concept-for-an-integrated-image-capture-and-analysis-system
#14
Safa Naraghi, Tinashe Mutsvangwa, René Goliath, Molebogeng X Rangaka, Tania S Douglas
BACKGROUND: The tuberculin skin test is the most widely used method for detecting latent tuberculosis infection in adults and active tuberculosis in children. We present the development of a mobile-phone based screening tool for measuring the tuberculin skin test induration. METHOD: The tool makes use of a mobile application developed on the Android platform to capture images of an induration, and photogrammetric reconstruction using Agisoft PhotoScan to reconstruct the induration in 3D, followed by 3D measurement of the induration with the aid of functions from the Python programming language...
May 8, 2018: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/29775773/trimeprazine-is-enantioselectively-degraded-by-an-activated-sludge-in-ready-biodegradability-test-conditions
#15
Laura Escuder-Gilabert, Yolanda Martín-Biosca, Mireia Perez-Baeza, Salvador Sagrado, María José Medina-Hernández
A great number of available pharmaceuticals are chiral compounds. Although they are usually manufactured as racemic mixtures, they can be enantioselectively biodegraded as a result of microbial processes. In this paper, a biodegradability assay in similar conditions to those recommended in OECD tests of enantiomers of trimeprazine (a phenothiazine employed as a racemate) is carried out. Experiments were performed in batch mode using a minimal salts medium inoculated with an activated sludge (collected from a Valencian Waste Water Treatment Plant, WWTP) and supplemented with the racemate...
May 9, 2018: Water Research
https://www.readbyqxmd.com/read/29775281/highly-stretchable-waterproof-fiber-asymmetric-supercapacitors-in-an-integrated-structure
#16
Kai Guo, Xianfu Wang, Lintong Hu, Tianyou Zhai, Huiqiao Li, Neng Yu
Fiber supercapacitors have attracted tremendous attention as promising power source candidates for next generation of wearable electronics, which are flexible, stretchable, and washable. Although asymmetric fiber supercapacitors with a high energy density have been achieved, their stretchability is no more than 200%, and they still face mechanical instability and unreliable waterproof structure. This work develops a highly integrated structure for waterproof, highly stretchable and asymmetric fiber-shaped supercapacitor, which is assembled by integrating a helix-shaped asymmetric fiber supercapacitor into a bifunctional polymer...
May 18, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29774539/clinical-and-molecular-characterization-of-indian-patients-with-fructose-1-6-bisphosphatase-deficiency-identification-of-a-frequent-variant-e281k
#17
Pratibha Bhai, Sunita Bijarnia-Mahay, Ratna D Puri, Renu Saxena, Deepti Gupta, Udhaya Kotecha, Anil Sachdev, Dhiren Gupta, Vyomesh Vyas, Divya Agarwal, Vivek Jain, Rajeev K Bansal, Tapisha G Kumar, Ishwar Chander Verma
Fructose-1, 6-bisphosphatase deficiency is an autosomal recessive disorder of gluconeogenesis caused by genetic defect in the FBP1 gene. It is characterized by episodic, often life-threatening metabolic acidosis, liver dysfunction, and hyperlactatemia. Without a high index of suspicion, it may remain undiagnosed with devastating consequences. Accurate diagnosis can be achieved either by enzyme assay or gene studies. Enzyme assay requires a liver biopsy and is tedious, invasive, expensive, and not easily available...
May 18, 2018: Annals of Human Genetics
https://www.readbyqxmd.com/read/29774538/oral-propranolol-in-the-treatment-of-proliferating-infantile-haemangiomas-the-british-society-for-paediatric-dermatology-consensus-guidelines
#18
L Solman, M Glover, P E Beattie, H Buckley, S Clark, J E Gach, A Giardini, I Helbling, R J Hewitt, B Laguda, S M Langan, A E Martinez, R Murphy, L Proudfoot, J Ravenscroft, H Shahidullah, L Shaw, S B Syed, L Wells, C Flohr
BACKGROUND: Infantile haemangiomas (IH) are the most common vascular tumours of infancy. Despite their frequency and potential complications, there are currently no unified UK guidelines for the treatment of IH with propranolol. There are still uncertainties and diverse opinions regarding indications, pre-treatment investigations, its use in PHACES syndrome, and cessation of treatment. METHODS: This study used a modified Delphi technique, which involved an international treatment survey, a systematic evidence review of the literature, a face-to-face multidisciplinary panel meeting and anonymous voting...
May 17, 2018: British Journal of Dermatology
https://www.readbyqxmd.com/read/29774177/the-new-direct-antiviral-agents-and-hepatitis-c-in-thoracic-transplantation-impact-on-donors-and-recipients
#19
REVIEW
Robert L Gottlieb, Shelley A Hall
Purpose of Review: The landscape of abdominal organ transplantation has been altered by the emergence of curative direct-acting antiviral agents for hepatitis C. Expansion of the thoracic donor pool to include the hearts and the lungs from hepatitis C-positive donors holds promise to increase available donor organs. Recent Findings: Case reports have documented separate lung and heart transplant patients who acquired, and then were cured of, donor-derived hepatitis C using these newer, more effective therapies...
2018: Current Transplantation Reports
https://www.readbyqxmd.com/read/29774085/quantum-chemical-dft-study-of-direct-and-h-and-c-assisted-co-dissociation-on-the-%C3%AF-fe-5-c-2-h%C3%A3-gg-carbide
#20
Robin J P Broos, Bart Zijlstra, Ivo A W Filot, Emiel J M Hensen
The first step in the Fischer-Tropsch reaction is the production of C1 monomers by the dissociation of the C-O bond. Although Fe is the active metal, it is well known that under typical reaction conditions, it changes into various carbide phases. The Hägg carbide (χ-Fe5 C2 ) phase is usually considered as the catalytically active phase. We carried out a comprehensive DFT study of CO dissociation on various surface terminations of the Hägg carbide, selected on their specific site topology and the presence of stepped sites...
May 10, 2018: Journal of Physical Chemistry. C, Nanomaterials and Interfaces
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