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https://www.readbyqxmd.com/read/28430512/simplifying-differential-equations-for-multiscale-feynman-integrals-beyond-multiple-polylogarithms
#1
Luise Adams, Ekta Chaubey, Stefan Weinzierl
In this Letter we exploit factorization properties of Picard-Fuchs operators to decouple differential equations for multiscale Feynman integrals. The algorithm reduces the differential equations to blocks of the size of the order of the irreducible factors of the Picard-Fuchs operator. As a side product, our method can be used to easily convert the differential equations for Feynman integrals which evaluate to multiple polylogarithms to an ϵ form.
April 7, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28430298/an-experimental-numerical-investigation-on-the-effects-of-macroporous-scaffold-geometry-on-cell-culture-parameters
#2
Hadis Eghbali, Michele M Nava, Gabriella Leonardi, Davod Mohebbi-Kalhori, Roberto Sebastiano, Abdolreza Samimi, Manuela T Raimondi
INTRODUCTION: Perfused bioreactors have been demonstrated to be effective in the delivery of nutrients and in the removal of waste products to and from the interior of cell-populated three-dimensional scaffolds. In this paper, a perfused bioreactor hosting a macroporous scaffold provided with a channel is used to investigate transport phenomena and culture parameters on cell growth. METHODS: MG63 human osteosarcoma cells were seeded on macroporous poly​(ε-caprolactone) scaffolds provided with a channel...
April 13, 2017: International Journal of Artificial Organs
https://www.readbyqxmd.com/read/28430260/optical-performance-enhancement-of-chip-on-board-light-emitting-diodes-through-ionic-wind-patterning
#3
Jiading Wu, Jingcao Chu, Zefeng Zhang, Jiahui Huang, Huai Zheng, Sheng Liu
Due to the total internal reflection at the upper interface of the encapsulation layer, the light extraction efficiency (LEE) of chip-on-board packaging light-emitting diodes is attenuated significantly. It is well known that the LEE can be enhanced by patterning the encapsulation layer. In this study, a novel method of patterning the encapsulation layer, which is based on the interaction between the ionic wind and liquid encapsulation, is proposed and demonstrated. Two kinds of encapsulation patterns, namely dual stripe and meniscus, were fabricated successfully...
April 20, 2017: Applied Optics
https://www.readbyqxmd.com/read/28430243/amplitude-versus-phase-effects-in-extreme-ultraviolet-lithography-mask-scattering-and-imaging
#4
Patrick P Naulleau, Markus Benk, Kenneth A Goldberg, Eric M Gullikson, Antoine Wojdyla, Yow-Gwo Wang, Andy Neureuther
It is now well established that extreme ultraviolet (EUV) mask multilayer roughness leads to wafer-plane line-width roughness (LWR) in the lithography process. Analysis and modeling done to date has assumed, however, that the roughness leading to scatter is primarily a phase effect and that the amplitude can be ignored. Under this assumption, simple scattering measurements can be used to characterize the statistical properties of the mask roughness. Here, we explore the implications of this simplifying assumption by modeling the imaging impacts of the roughness amplitude component as a function of the balance between amplitude and phase induced scatter...
April 20, 2017: Applied Optics
https://www.readbyqxmd.com/read/28429723/pressure-self-focusing-effect-and-novel-methods-for-increasing-the-maximum-pressure-in-traditional-and-rotational-diamond-anvil-cells
#5
Biao Feng, Valery I Levitas
The main principles of producing a region near the center of a sample, compressed in a diamond anvil cell (DAC), with a very high pressure gradient and, consequently, with high pressure are predicted theoretically. The revealed phenomenon of generating extremely high pressure gradient is called the pressure self-focusing effect. Initial analytical predictions utilized generalization of a simplified equilibrium equation. Then, the results are refined using our recent advanced model for elastoplastic material under high pressures in finite element method (FEM) simulations...
April 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28429369/variation-in-brain-anatomy-in-frogs-and-its-possible-bearing-on-their-locomotor-ecology
#6
Adriana S Manzano, Anthony Herrel, Anne-Claire Fabre, Virginia Abdala
Despite the long-standing interest in the evolution of the brain, relatively little is known about variation in brain anatomy in frogs. Yet, frogs are ecologically diverse and, as such, variation in brain anatomy linked to differences in lifestyle or locomotor behavior can be expected. Here we present a comparative morphological study focusing on the macro- and micro-anatomy of the six regions of the brain and its choroid plexus: the olfactory bulbs, the telencephalon, the diencephalon, the mesencephalon, the rhombencephalon, and the cerebellum...
April 20, 2017: Journal of Anatomy
https://www.readbyqxmd.com/read/28429066/atmospheric-pressure-maldi-for-the-noninvasive-characterization-of-carbonaceous-ink-from-renaissance-documents
#7
Giuseppe Grasso, Marzia Calcagno, Alessandro Rapisarda, Roberta D'Agata, Giuseppe Spoto
The analytical methods that are usually applied to determine the compositions of inks from ancient manuscripts usually focus on inorganic components, as in the case of iron gall ink. In this work, we describe the use of atmospheric pressure/matrix-assisted laser desorption ionization-mass spectrometry (AP/MALDI-MS) as a spatially resolved analytical technique for the study of the organic carbonaceous components of inks used in handwritten parts of ancient books for the first time. Large polycyclic aromatic hydrocarbons (L-PAH) were identified in situ in the ink of XVII century handwritten documents...
April 21, 2017: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/28429059/a-novel-method-to-recover-inclusion-body-protein-from-recombinant-e-coli-fed-batch-processes-based-on-phage-%C3%AE-x174-derived-lysis-protein-e
#8
Daniela Ehgartner, Patrick Sagmeister, Timo Langemann, Andrea Meitz, Werner Lubitz, Christoph Herwig
Production of recombinant proteins as inclusion bodies is an important strategy in the production of technical enzymes and biopharmaceutical products. So far, protein from inclusion bodies has been recovered from the cell factory through mechanical or chemical disruption methods, requiring additional cost-intensive unit operations. We describe a novel method that is using a bacteriophage-derived lysis protein to directly recover inclusion body protein from Escherichia coli from high cell density fermentation process: The recombinant inclusion body product is expressed by using a mixed feed fed-batch process which allows expression tuning via adjusting the specific uptake rate of the inducing substrate...
April 20, 2017: Applied Microbiology and Biotechnology
https://www.readbyqxmd.com/read/28429017/oligonucleotide-promoted-peptide-bond-formation-using-a-trna-mimicking-approach
#9
H-P Mattelaer, C-A Mattelaer, N Papastavrou, W Dehaen, P Herdewijn
TransferRNA's role in protein translation is the prime example of an Informational Leaving Group (ILG). A simplified model produced oligophenylalanine with a modified uracil as an ILG in the presence of specific oligonucleotides. Our preliminary studies contribute to the importance of hybrid species in bridging the gap between peptides and nucleic acids.
April 21, 2017: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/28428758/modulation-of-asymmetric-flux-in-heterotypic-gap-junctions-by-pore-shape-particle-size-and-charge
#10
Abhijit Mondal, Frank B Sachse, Alonso P Moreno
Gap junction channels play a vital role in intercellular communication by connecting cytoplasm of adjoined cells through arrays of channel-pores formed at the common membrane junction. Their structure and properties vary depending on the connexin isoform(s) involved in forming the full gap junction channel. Lack of information on the molecular structure of gap junction channels has limited the development of computational tools for single channel studies. Currently, we rely on cumbersome experimental techniques that have limited capabilities...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28428655/magnetic-resonance-imaging-of-the-cirrhotic-liver-diagnosis-of-hepatocellular-carcinoma-and-evaluation-of-response-to-treatment-part-2
#11
REVIEW
Miguel Ramalho, António P Matos, Mamdoh AlObaidy, Fernanda Velloni, Ersan Altun, Richard C Semelka
In the second part of this review, we will describe the ancillary imaging features of hepatocellular carcinoma (HCC) that can be seen on standard magnetic resonance imaging (MRI) protocol, and on novel and emerging protocols such as diffusion weighted imaging and utilization of hepatocyte-specific/hepatobiliary contrast agent. We will also describe the morphologic sub-types of HCC, and give a simplified non-invasive diagnostic algorithm for HCC, followed by a brief description of the liver imaging reporting and data system (LI-RADS), and MRI assessment of tumor response following locoregional therapy...
March 2017: Radiologia Brasileira
https://www.readbyqxmd.com/read/28428361/single-tube-dodecaplex-pcr-panel-of-polymorphic-microsatellite-markers-closely-linked-to-the-dmpk-ctg-repeat-for-preimplantation-genetic-diagnosis-of-myotonic-dystrophy-type-1
#12
Mulias Lian, Mingjue Zhao, Caroline G Lee, Samuel S Chong
BACKGROUND: Preimplantation genetic diagnosis (PGD) of myotonic dystrophy type 1 (DM1) currently uses conventional PCR to detect nonexpanded dystrophia myotonica protein kinase (DMPK) alleles or triplet-primed PCR to detect the CTG-expanded alleles, coupled with analysis of linked microsatellite markers to increase diagnostic accuracy. We aimed to simplify the process of identification and selection of informative linked markers for application to DM1 PGD. METHODS: An in silico search was performed to identify all markers within 1-1...
April 20, 2017: Clinical Chemistry
https://www.readbyqxmd.com/read/28427957/pcr-based-identification-of-trypanosoma-lewisi-and-trypanosoma-musculi-using-maxicircle-kinetoplast-dna
#13
Xiao-Kun Hong, Xuan Zhang, Octavio Alejandro Fusco, You-Gen Lan, Zhao-Rong Lun, De-Hua Lai
Trypanosoma lewisi, transmitted by rat fleas, is a widespread pathogen specific to rats with records of human infection cases. Its closely related species with global distribution, Trypanosoma musculi, is transmitted between mice by ingestion of infected fleas. These trypanosomes are of similar morphology, making it difficult to distinguish them by microscopy. In this study, we have developed a rapid, sensitive and reliable PCR method for the diagnosis of T. lewisi and T. musculi. The T. lewisi-specific amplicons were not produced by other Trypanosoma, such as T...
April 17, 2017: Acta Tropica
https://www.readbyqxmd.com/read/28427949/parasitism-finds-many-solutions-to-the-same-problems-in-red-algae-florideophyceae-rhodophyta
#14
Jillian M Freese, Christopher E Lane
Parasitic red algae evolve from a common ancestor with their hosts, parasitizing cousins using familiar cellular mechanisms. They have independently evolved over one hundred times within the exclusively multicellular red algal class Florideophyceae. Reduced morphology, a lack of pigmentation, and direct cell-cell connections with their hosts are markers of red algal parasitism. With so many potential evolutionary pathways, red algal parasite diversity offers a unique test case to understand the earliest stages of this lifestyle transition...
April 17, 2017: Molecular and Biochemical Parasitology
https://www.readbyqxmd.com/read/28427719/improved-finite-control-set-model-predictive-control-for-active-front-end-rectifiers-with-simplified-computational-approach-and-on-line-parameter-identification
#15
Xing Liu, Dan Wang, Zhouhua Peng
In this paper, an improved finite-control-set model predictive control method is proposed for active front-end rectifiers where the computational effort and parameter mismatch problems are taken into account simultaneously. Specifically, a desired voltage vector which only requires one exploration is directly selected by using a single cost function, and the process of selection of the desired voltage vector is optimized by using a sector distribution method. Meanwhile, a model reference adaptive system-based online parameter identification approach is presented to alleviate the parameter mismatch problem...
April 17, 2017: ISA Transactions
https://www.readbyqxmd.com/read/28427442/effect-of-acupuncture-in-prevention-and-treatment-of-chemotherapy-induced-nausea-and-vomiting-in-patients-with-advanced-cancer-study-protocol-for-a-randomized-controlled-trial
#16
Qi-Wei Li, Ming-Wei Yu, Guo-Wang Yang, Xiao-Min Wang, Huan Wang, Chen-Xi Zhang, Na Xue, Wei-Ru Xu, Qi Fu, Zhong Yang, Lin Yang
BACKGROUND: Chemotherapy-induced nausea and vomiting (CINV) is one of the most common and distressing side effects in patients with cancer. The introduction and development of antiemetic drugs have significantly improved the ability of clinicians to control CINV, but it is not easy to translate to practical application, owing to financial issues, provider-related barriers, and patient factors. Nondrug therapies are needed to alleviate the symptoms of CINV. Acupuncture is an appropriate adjunctive treatment for CINV, but additional evidence is needed...
April 20, 2017: Trials
https://www.readbyqxmd.com/read/28427304/translating-u-500r-randomized-clinical-trial-evidence-to-the-practice-setting-a-diabetes-educator-expert-prescriber-team-approach
#17
Paula M Bergen, Davida F Kruger, April D Taylor, Wael E Eid, Arti Bhan, Jeffrey A Jackson
Purpose The purpose of this article is to provide recommendations to the diabetes educator/expert prescriber team for the use of human regular U-500 insulin (U-500R) in patients with severely insulin-resistant type 2 diabetes, including its initiation and titration, by utilizing dosing charts and teaching materials translated from a recent U-500R clinical trial. Conclusions Clinically relevant recommendations and teaching materials for the optimal use and management of U-500R in clinical practice are provided based on the efficacy and safety results of and lessons learned from the U-500R clinical trial by Hood et al, current standards of practice, and the authors' clinical expertise...
April 1, 2017: Diabetes Educator
https://www.readbyqxmd.com/read/28427065/emerging-simplified-retinal-imaging
#18
Ashish Sharma
Diabetic retinopathy (DR), a major microvascular complication of diabetes, has a significant impact on the world's health systems. Globally, the number of people with DR will grow from 126.6 million in 2010 to 191.0 million by 2030, and it is estimated that the number with vision-threatening diabetic retinopathy will increase from 37.3 million to 56.3 million if prompt action is not taken. Lack of early diagnosis and management is the leading cause of blindness in working-age populations The gap between demand and annual eye examinations has been a big challenge...
2017: Developments in Ophthalmology
https://www.readbyqxmd.com/read/28427060/the-eye-as-a-window-to-the-microvascular-complications-of-diabetes
#19
Gianpaolo Zerbini, Silvia Maestroni, Valentina Turco, Antonio Secchi
Although microvascular complications of diabetes (retinopathy, neuropathy, and nephropathy) affect different organs, they are strongly correlated to each other. Based on recent data, their onset and progression could be directly monitored, focusing our attention only on the eye. When confirmed and standardized, this approach could allow one to simplify the way in which we follow the progression of different diabetic complications, and thus establish new strategies aimed at preventing, treating and, hopefully, inducing the remission of microvascular complications of diabetes...
2017: Developments in Ophthalmology
https://www.readbyqxmd.com/read/28427005/diagnostic-accuracy-of-magnetic-resonance-imaging-in-patients-with-suspected-pulmonary-embolism-a-bivariate-meta-analysis
#20
REVIEW
Alessandro Squizzato, Fulvio Pomero, Attilio Allione, Roberto Priotto, Nicoletta Riva, Menno V Huisman, Frederikus A Klok, Paul D Stein, Luigina Guasti, Luigi Fenoglio, Francesco Dentali, Walter Ageno
BACKGROUND: Computed tomographic pulmonary angiography (CTPA) has simplified the diagnostic approach to patients with clinically suspected pulmonary embolism (PE), but alternative imaging tests are still advocated. We aimed to systematically assess the diagnostic accuracy of magnetic resonance imaging (MRI) for PE diagnosis. METHODS: Studies evaluating the diagnostic accuracy of MRI for the diagnosis of PE were systematically searched in the PubMed and EMBASE databases (up to May 2016)...
April 7, 2017: Thrombosis Research
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