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Todd Belding
No abstract text is available yet for this article.
January 1, 2018: Journal of Pharmacy Practice
Katherine A Araque, Deepak K Kadayakkara, Nino Gigauri, Diane Sheehan, Sachin Majumdar, Gregory Buller, Clare A Flannery
Background: Severe hypoglycaemic events (HGEs) in hospitalised patients are associated with poor outcomes and prolonged hospitalization. Systematic, coordinated care is required for acute management and prevention of HGEs; however, studies evaluating quality control efforts are scarce. Objective: To investigate the effectiveness of system-based interventions to improve management response to HGEs. Methods: System-based interventions were designed and implemented following a root cause analysis of HGE in adult patients with diabetes from two general medical wards with the highest incidence of HGE...
2018: BMJ Open Quality
Allan Fong, Nicole Harriott, Donna M Walters, Hanan Foley, Richard Morrissey, Raj R Ratwani
OBJECTIVES: Many healthcare providers have implemented patient safety event reporting systems to better understand and improve patient safety. Reviewing and analyzing these reports is often time consuming and resource intensive because of both the quantity of reports and length of free-text descriptions in the reports. METHODS: Natural language processing (NLP) experts collaborated with clinical experts on a patient safety committee to assist in the identification and analysis of medication related patient safety events...
August 2017: International Journal of Medical Informatics
Julian Ehlers, Jörg U Ganzhorn, Cornelia Silaghi, Andreas Krüger, Daniela Pothmann, R Yedidya Ratovonamana, Alexandra Veit, Christian Keller, Sven Poppert
Little is known about the role of endemic ticks as vectors for bacterial and protozoan pathogens for animals and humans in Madagascar and their interaction in anthropogenic habitats where humans, their livestock and native Malagasy species (vectors and hosts) come into more frequent contact than in natural forest ecosystems. The aims of the study were (1) to test whether habitat degradation is associated with increased infestation of tortoises by ticks and (2) to investigate whether ticks carried Babesia, Borrelia or Rickettsia species that might be pathogenic for humans and livestock...
March 2016: Ticks and Tick-borne Diseases
Keita Sakakibara, Takuya Fujisawa, Jonathan P Hill, Katsuhiko Ariga
Methyl xylopyranoside containing three 4-(pyrene-1-yl)benzoyl groups (PyXy) undergoes conformational interchange within a Langmuir monolayer upon mechanical compression. This xylose-type molecular machine PyXy was immobilized within two different matrix lipids, methyl stearate and methyl 2,3,4-tri-O-stearoyl-β-D-xylopyranoside, which respectively form rigid and soft monolayers. Structural properties of the monolayer were characterized by assessing the compressibility, compression modulus, and ideal limiting molecular area of PyXy, all of which were estimated from the π-A isotherm measurements...
June 14, 2014: Physical Chemistry Chemical Physics: PCCP
Higgins T, M Heelon, B Siano, L Douglass, P Liebro, B Spath, N Kudler, G Kerr
OBJECTIVE: To report the incidence and severity of medication safety events before and after initiation of barcode scanning for positive patient identification (PPID) in a large teaching hospital. METHODS: Retrospective analysis of data from an existing safety reporting system with anonymous and non-punitive self-reporting. Medication safety events were categorized as "near-miss" (unsafe conditions or caught before reaching the patient) or reaching the patient, with requisite additional monitoring or treatment...
2010: Applied Clinical Informatics
Gianna Giachi, Pasquino Pallecchi, Antonella Romualdi, Erika Ribechini, Jeannette Jacqueline Lucejko, Maria Perla Colombini, Marta Mariotti Lippi
In archaeology, the discovery of ancient medicines is very rare, as is knowledge of their chemical composition. In this paper we present results combining chemical, mineralogical, and botanical investigations on the well-preserved contents of a tin pyxis discovered onboard the Pozzino shipwreck (second century B.C.). The contents consist of six flat, gray, discoid tablets that represent direct evidence of an ancient medicinal preparation. The data revealed extraordinary information on the composition of the tablets and on their possible therapeutic use...
January 22, 2013: Proceedings of the National Academy of Sciences of the United States of America
David F Greene, Michael Hesketh, Edith Pounden
We studied the density of ascocarps (mushrooms) of morels (Morchella) and pixie cups (Geo-pyxis carbonaria) as a function of postfire duff (forest floor organic layer) depth in the first 4 y after a wildfire. The great majority of ascocarps of both species appeared in the first summer (2004) after an Aug 2003 fire in predominantly pine-spruce montane stands in Kootenay National Park, British Columbia. The spatial distribution of the ascocarps of both species was strongly biased toward (i) microsites with thin postfire duff and (ii) proximity to standing burned tree trunks...
July 2010: Mycologia
Rebecca K Aulbach, Kathy Brient, Marie Clark, Kristi Custard, Carolyn Davis, Jonathan Gecomo, Judy Ong Ho
A multidisciplinary safety initiative transformed blood transfusion practices at St. Luke's Episcopal Hospital in Houston, Texas. An intense analysis of a mistransfusion using the principles of a Just Culture and the process of Cause Mapping identified system and human performance factors that led to the transfusion error. Multiple initiatives were implemented including technology, education and human behaviour change. The wireless technology of Pyxis Transfusion Verification by CareFusion is effective with the rapid infusion module efficient for use in critical care...
June 2010: Critical Care Nursing Clinics of North America
Maureen Straight
This study sought to evaluate the impact of an online self-learning module on nurse knowledge and use of the Lexi-Comp feature of the Pyxis MedStation Rx 2000 system, a point-of-care medication delivery system. Data were collected among nurse-users at a community-based healthcare organization (N = 41). Pre- and post-training surveys were used to evaluate training effects. After training, completion of the tutorial and knowledge and use of the Lexi-Comp feature increased by 23% and 56%, respectively. One month after training, a drop in medication errors on administration at the healthcare organization was observed...
January 2008: Computers, Informatics, Nursing: CIN
Minh Le, Christopher J Raxworthy, William P McCord, Lisa Mertz
Although tortoises of the family Testudinidae represent a familiar and widely distributed group of turtles, their phylogenetic relationships have remained contentious. In this study, we included 32 testudinid species (all genera and subgenera, and all species of Geochelone, representing 65% of the total familial species diversity), and both mitochondrial (12S rRNA, 16S rRNA, and cytb) and nuclear (Cmos and Rag2) DNA data with a total of 3387 aligned characters. Using diverse phylogenetic methods (Maximum Parsimony, Maximum Likelihood, and Bayesian Analysis) congruent support is found for a well-resolved phylogeny...
August 2006: Molecular Phylogenetics and Evolution
Andrew V Romero, Daniel C Malone
PURPOSE: The accuracy of adverse-drug-event (ADE) reports collected using an automated dispensing system was evaluated. METHODS: ADE reports were collected by requiring nurses on five units in a tertiary care facility to select a reason for removing two tracer drugs (dextrose injection 50% [D50] and naloxone) from an automated dispensing system (Medstation 2000, Pyxis, San Diego, CA). The accuracy of the ADE reports during a period of 4.5 months was evaluated through retrospective chart review...
July 1, 2005: American Journal of Health-system Pharmacy: AJHP
Cheng-Fu Chang, Ka-Man Wai, Hugh G Patterton
Physical clusters of co-regulated, but apparently functionally unrelated, genes are present in many genomes. Despite the important implication that the genomic environment contributes appreciably to the regulation of gene expression, no simple statistical method has been described to identify physical clusters of co-regulated genes. Here we report the development of a model that allows the direct calculation of the significance of such clusters. We have implemented the derived statistical relation in a software program, Pyxis, and have analyzed a selection of Saccharomyces cerevisiae gene expression microarray data sets...
2004: Nucleic Acids Research
Lars Kroener, Frank Musshoff, Burkhard Madea
Four commonly used immunoassay kits were evaluated for their efficiency in screening for drugs of abuse in whole blood. Six groups of illicit drugs (opiates, cannabinoids, amphetamines, cocain and benzoylecgonine, benzodiazepines, and methadone) were determined by using the homogenous assays ADx and CEDIA DAU and compared with the results produced by means of the inhomogenous assays MTP and Pyxis 24. The measured 86 blood samples were taken from authentic routine analyses between February and September, 2000...
May 2003: Journal of Analytical Toxicology
Christopher E Schmidt, Thomas Bottoni
INTRODUCTION: Medication errors are well documented in medical literature and the lay press. Through participation in a nationwide institute for healthcare improvement initiative, our emergency department performance improvement group focused on human and system factors that contributed to potential medication errors. METHODS: A survey conducted of ED staff examined barriers to reporting medication errors and potential "near misses." members of the emergency department performance improvement group examined contents of the ed Pyxis machines, assessing medications that physically resembled one another, similar sounding medications located in close proximity, and medications available in differing doses...
February 2003: Journal of Emergency Nursing: JEN: Official Publication of the Emergency Department Nurses Association
Eric P Palkovacs, Justin Gerlach, Adalgisa Caccone
Today, the only surviving wild population of giant tortoises in the Indian Ocean occurs on the island of Aldabra. However, giant tortoises once inhabited islands throughout the western Indian Ocean. Madagascar, Africa, and India have all been suggested as possible sources of colonization for these islands. To address the origin of Indian Ocean tortoises (Dipsochelys, formerly Geochelone gigantea), we sequenced the 12S, 16S, and cyt b genes of the mitochondrial DNA. Our phylogenetic analysis shows Dipsochelys to be embedded within the Malagasy lineage, providing evidence that Indian Ocean giant tortoises are derived from a common Malagasy ancestor...
August 2002: Molecular Phylogenetics and Evolution
Deborah Blazys
No abstract text is available yet for this article.
April 2002: Journal of Emergency Nursing: JEN: Official Publication of the Emergency Department Nurses Association
R S Krishnan
No abstract text is available yet for this article.
June 1999: Hospital Material[dollar Sign] Management
A Caccone, G Amato, O C Gratry, J Behler, J R Powell
Four of the five tortoise species in Madagascar, Pyxis arachnoides, P. planicauda, Geochelone radiata, and G. yniphora, are endemic and on the verge of extinction. Their phylogenetic relationships remain controversial and unresolved. Here we address the phylogeny of this group using DNA sequences for the 12S and 16S rDNA and cyt b genes in mitochondrial DNA. As outgroups we used two species of Geochelone, pardalis (mainland Africa) and nigra (Galápagos), as well as a more distant North American tortoise, Gopherus polyphemus...
June 1999: Molecular Phylogenetics and Evolution
L Scott
No abstract text is available yet for this article.
June 26, 1995: Modern Healthcare
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