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https://www.readbyqxmd.com/read/28529113/integrating-natural-language-processing-expertise-with-patient-safety-event-review-committees-to-improve-the-analysis-of-medication-events
#1
Allan Fong, Nicole Harriott, Donna M Walters, Hanan Foley, Richard Morrissey, Raj R Ratwani
OBJECTIVES: Many healthcare providers have implemented patient safety event reporting systems to better understand and improve patient safety. Reviewing and analyzing these reports is often time consuming and resource intensive because of both the quantity of reports and length of free-text descriptions in the reports. METHODS: Natural language processing (NLP) experts collaborated with clinical experts on a patient safety committee to assist in the identification and analysis of medication related patient safety events...
May 11, 2017: International Journal of Medical Informatics
https://www.readbyqxmd.com/read/28514641/mapping-workforce-configuration-and-operational-models-in-australian-emergency-departments-a-national-survey
#2
Glenn Gardner, Anne Gardner, Sandy Middleton, Julie Considine, Gerard Fitzgerald, Luke Christofis, Anna Doubrovsky, Margaret Adams, Jane O'Connell
Objective Hospital emergency departments (ED) in Australia and internationally have been experiencing increased demand, resulting in reduced hospital quality, impaired access and adverse health outcomes. Effective evaluation of new ED service models and their effect on outcomes is reliant on baseline measures of the staffing configuration and organisational characteristics of the EDs being studied. The aim of the present study was to comprehensively measure these variables in Australian EDs.Methods Australian hospital EDs with 24-h medical and nursing cover were identified and invited to participate in the study...
May 18, 2017: Australian Health Review: a Publication of the Australian Hospital Association
https://www.readbyqxmd.com/read/28473230/a-philosophical-framework-for-pharmacy-in-the-21st-century-guided-by-ethical-principles
#3
Stephen B Duffull, Daniel F B Wright, Carlo A Marra, Megan G Anakin
Pharmacy has a long history of providing products and services for healthcare. In the last century, these roles have taken a strong focus on clinical care with the provision of medicines review, medicines optimisation, and prescribing services being at the forefront. The profession, however, is diverse. Pharmacists operate across a wide range of healthcare practices that often embrace both historic and contemporary roles simultaneously. The purpose of this article is to provide an overarching philosophical framework for pharmacy that encompasses roles that the modern pharmacist may assume...
April 28, 2017: Research in Social & Administrative Pharmacy: RSAP
https://www.readbyqxmd.com/read/28459897/association-of-inpatient-antimicrobial-utilization-measures-with-antimicrobial-stewardship-activities-and-facility-characteristics-of-veterans-affairs-medical-centers
#4
Christopher J Graber, Makoto M Jones, Ann F Chou, Yue Zhang, Matthew Bidwell Goetz, Karl Madaras-Kelly, Matthew H Samore, Peter A Glassman
BACKGROUND: Antimicrobial stewardship programs (ASPs) have been advocated to improve antimicrobial utilization, but program implementation is variable. Antimicrobial stewardship programs (ASPs) have been advocated to improve antimicrobial utilization, but program implementation is variable. OBJECTIVE: To determine associations between ASPs and facility characteristics, and inpatient antimicrobial utilization measures in the Veterans Affairs (VA) system in 2012. DESIGN: In 2012, VA administered a survey on antimicrobial stewardship practices to designated ASP contacts at VA acute care hospitals...
May 2017: Journal of Hospital Medicine: An Official Publication of the Society of Hospital Medicine
https://www.readbyqxmd.com/read/28458370/stability-of-mixed-preparations-consisting-of-commercial-moisturizing-creams-with-an-ointment-base-investigated-by-magnetic-resonance-imaging
#5
Yoshinori Onuki, Chiaki Funatani, Yoshihisa Yamamoto, Toshiro Fukami, Tatsuo Koide, Yoshihiro Hayashi, Kozo Takayama
A moisturizing cream mixed with a steroid ointment is frequently prescribed to patients suffering from atopic dermatitis. However, there is a concern that the mixing operation causes destabilization. The present study was performed to investigate the stability of such preparations closely using magnetic resonance imaging (MRI). As sample preparations, five commercial moisturizing creams that are popular in Japan were mixed with an ointment base, a white petrolatum, at a volume ratio of 1 : 1. The mixed preparations were stored at 60°C to accelerate the destabilization processes...
2017: Chemical & Pharmaceutical Bulletin
https://www.readbyqxmd.com/read/28455085/randomized-controlled-trial-of-intravenous-acetaminophen-for-postcesarean-delivery-pain-control
#6
Brie Altenau, Catrina C Crisp, C Ganga Devaiah, Donna S Lambers
BACKGROUND: Cesarean delivery is a common surgery in the United States, with 1.3 million performed during 2009.(1) Obstetricians must balance the growing concern with opioid abuse, dependence, and side effects with optimal postoperative pain control. Intravenous acetaminophen may represent an additional method to decrease the reliance on opioid medications and improve postoperative pain following cesarean delivery. OBJECTIVE: The objective of the study was to determine whether the administration of intravenous acetaminophen following routine scheduled cesarean delivery would decrease the need for narcotic medications to control postoperative pain...
April 25, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28452917/quality-of-handoffs-in-community-pharmacies
#7
Ephrem Abebe, Jamie A Stone, Corey A Lester, Michelle A Chui
OBJECTIVES: The aims of the study were to characterize handoffs in community pharmacies and to examine factors that contribute to perceived handoff quality. METHODS: A cross-sectional study of community pharmacists in a Midwest State of the United States. Self-administered questionnaires were used to collect information on participant and practice setting characteristics. Data were analyzed using descriptive statistics and multivariate logistic regression. RESULTS: A total of 445 completed surveys were returned (response rate, 82%)...
April 27, 2017: Journal of Patient Safety
https://www.readbyqxmd.com/read/28444026/use-of-pharmacy-records-to-measure-treatment-adherence-a-critical-review-of-the-literature
#8
Elisangela da Costa Lima-Dellamora, Claudia Garcia Serpa Osorio-de-Castro, Livia Gonçalves Dos Santos Lima Madruga, Thiago Botelho Azeredo
The current frame of reference on adherence to pharmacotherapy includes a set of behaviors experienced by the user, with observation of the detailed and continuous history of the use of each dose of the medication. Indicators based on pharmacy records have been used to measure adherence. The current review aimed to identify and describe indicators based on pharmacy records and to discuss their adequacy and limitations for measuring adherence. An exploratory literature review was conducted in three databases using the terms "adherence", "pharmacy records/administrative data", and "measure" to compose the descriptors for the selection of 81 articles and the elaboration of a chart with the denomination, sources, methods for calculation, description, and interpretation of the operational and referential meaning of 14 indicators...
April 20, 2017: Cadernos de Saúde Pública
https://www.readbyqxmd.com/read/28432189/safety-and-efficiency-of-a-new-generic-package-labelling-a-before-and-after-study-in-a-simulated-setting
#9
Beate Hennie Garcia, Renate Elenjord, Camilla Bjornstad, Kjell Hermann Halvorsen, Sigurd Hortemo, Steinar Madsen
BACKGROUND: Medication errors are frequent and may cause harm to patients and increase healthcare expenses. AIM: To explore whether a new labelling influences time and errors when preparing medications in accordance with medication charts in an experimental setting. METHOD: We carried out an uncontrolled before and after study with 3 months inbetween experiments. Phase I used original labelling and phase II used new generic labelling. We set up an experimental medicine room, simulating a real-life setting...
April 21, 2017: BMJ Quality & Safety
https://www.readbyqxmd.com/read/28415406/pcl-foamed-scaffolds-loaded-with-5-fluorouracil-anti-cancer-drug-prepared-by-an-eco-friendly-route
#10
Aurelio Salerno, Concepción Domingo, Javier Saurina
This study describes a new preparation method, which combines freeze drying and supercritical CO2 foaming approaches, for the preparation of drug delivery scaffolds of polycaprolactone loaded with 5-fluorouracil, an anti-cancer drug, with low solubility in scCO2. It is a principal objective of this work to design a scCO2 strategy to reduce 5-Fu solubility limitations in its homogeneous distribution into a PCL scaffold through the design of an innovative processing method. The design of this process is considered valuable for the development of clean technology in pharmacy and medicine, since most of the active agents have a null solubility in scCO2·Supercritical CO2 is used as a blowing agent to induce polymer foaming by means of the low temperature pressure quench process...
June 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28400254/community-pharmacist-delivered-medicare-annual-wellness-visits-within-a-family-medicine-practice
#11
Taylor A Evans, Patricia H Fabel, Bryan Ziegler
OBJECTIVE: To identify the steps to implement a community pharmacist into a family medicine practice to deliver Medicare Annual Wellness Visits (AWVs). SETTING: Medicine Mart Pharmacy is a locally owned and operated pharmacy that has served the West Columbia, South Carolina, area for over 30 years. The services offered by the pharmacy have expanded over the past 3 years through the addition of a community pharmacy resident. PRACTICE INNOVATION: A stepwise approach was developed for a community pharmacist to identify, market, and establish an AWV service through a collaborative practice agreement with a local family medicine practice...
April 8, 2017: Journal of the American Pharmacists Association: JAPhA
https://www.readbyqxmd.com/read/28400253/perceived-sustainability-of-community-telepharmacy-in-north-dakota
#12
David M Scott, Daniel L Friesner, Teri Undem, Gabrielle Anderson, Kelli Sem, Charles D Peterson
OBJECTIVES: To assess the sustainability of the business model underlying the North Dakota Telepharmacy Project (NDTP). SETTING: Of the 38 community pharmacy organizations (14 central, 24 remote), 27 organizations (11 central and 16 remote sites) in North Dakota provided a useable set of responses (71.1% response rate). A twelfth organization (a community pharmacy) ceased operations over the study's time frame and was not included in the data analysis. PRACTICE DESCRIPTION: Emphasis is placed on NDTP community telepharmacies, because the community telepharmacy business model is more established than hospital telepharmacies...
April 8, 2017: Journal of the American Pharmacists Association: JAPhA
https://www.readbyqxmd.com/read/28377378/evaluation-of-racial-and-socioeconomic-disparities-in-medication-pricing-and-pharmacy-access-and-services
#13
Marie A Chisholm-Burns, Christina A Spivey, Justin Gatwood, Adam Wiss, Kenneth Hohmeier, Steven R Erickson
PURPOSE: Results of a study to determine if disparities in drug pricing, pharmacy services, and community pharmacy access exist in a Tennessee county with a predominantly minority population are reported. METHODS: A cross-sectional survey of community pharmacies in Shelby County, a jurisdiction with a total population more than 60% composed of racial and ethnic minority groups, was conducted. Data collection included "out-of-pocket" (i.e., cash purchase) prices for generic levothyroxine, methylphenidate, and hydrocodone-acetaminophen; pharmacy hours of operation; availability of selected pharmacy services; and ZIP code-level data on demographics and crime risk...
May 15, 2017: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/28376815/comparison-of-six-methods-to-estimate-adherence-in-an-art-na%C3%A3-ve-cohort-in-a-resource-poor-setting-which-best-predicts-virological-and-resistance-outcomes
#14
Catherine Orrell, Karen Cohen, Rory Leisegang, David R Bangsberg, Robin Wood, Gary Maartens
BACKGROUND: Incomplete adherence to antiretroviral therapy (ART) results in virologic failure and resistance. It remains unclear which adherence measure best predicts these outcomes. We compared six patient-reported and objective adherence measures in one ART-naïve cohort in South Africa. METHODS: We recruited 230 participants from a community ART clinic and prospectively collected demographic data, CD4 count and HIV-RNA at weeks 0, 16 and 48. We quantified adherence using 3-day self-report (SR), clinic-based pill count (CPC), average adherence by pharmacy refill (PR-average), calculation of medication-free days (PR-gaps), efavirenz therapeutic drug monitoring (TDM) and an electronic adherence monitoring device (EAMD)...
April 4, 2017: AIDS Research and Therapy
https://www.readbyqxmd.com/read/28364933/when-technical-achievements-aren-t-enough-lessons-learned-from-efforts-to-catalyze-policy-action-on-supply-chain-in-senegal
#15
Modibo Dicko, Batouo Souare, Lamine Cisse Sarr, Babacar Gueye
Before 2013, Senegal public health supply system was pull-based and fully public-run. Lengthy and recurrent stockouts of essential health products (incl. contraceptives) were the rule, not the exception as they used to strike more than 80% of public service delivery points (SDPs). Following a successful pilot in two districts in 2012, the Senegalese Ministry of Health and Social Action (MSAS) implemented the Informed Push Model (IPM) Project (2013-2016). In its first two years, IPM bridged key gaps and expanded the distribution of contraceptives by private third party logistics operators to all public SDPs in Senegal and nearly eliminated stockouts...
April 19, 2017: Vaccine
https://www.readbyqxmd.com/read/28356213/organizational-readiness-for-change-preceptor-perceptions-regarding-early-immersion-of-student-pharmacists-in-health-system-practice
#16
Kimberly A Sanders, Michael D Wolcott, Jacqueline E McLaughlin, Amanda D'Ostroph, Christopher M Shea, Nicole R Pinelli
PURPOSE: To examine preceptors' perceptions regarding readiness for change pre- and post-implementation of a pilot early immersion program engaging student pharmacists in direct patient care. METHODS: Student pharmacists enrolled in the second professional year of a Doctor of Pharmacy degree program completed a four-week health-system introductory pharmacy practice experience (IPPE) which was modified to include direct patient care roles in operational (drug preparation and dispensing) and clinical (comprehensive medication management) pharmacy environments...
March 10, 2017: Research in Social & Administrative Pharmacy: RSAP
https://www.readbyqxmd.com/read/28347563/structural-and-elemental-characterization-of-traditional-indian-siddha-formulation-thalagak-karuppu
#17
N Kannan, S Balaji, N V Anil Kumar
BACKGROUND: The traditional Indian medicine 'Siddha' uses metals, metalloids and minerals including toxic ones with no proven toxicity. Thalagak karuppu (TK) is remarkably stable over a century and used for treating Suram (Fever), Kaasam (Cough), Elai (Tuberculosis) and Eraippu Erumal (Bronchial Asthma). OBJECTIVE: The present study addresses elemental and morphological characterization of therapeutic Siddha formulation: Thalagak karuppu (TK). MATERIALS AND METHODS: TK was purchased from the Indian Medical Practitioners Co-operative Pharmacy and Stores (IMCOPS) Ltd, Chennai, Tamilnadu, India...
March 24, 2017: Journal of Ayurveda and Integrative Medicine
https://www.readbyqxmd.com/read/28346209/accuracy-considerations-in-sterile-compounding
#18
Michael J Akers
Published information about the accuracy of filling and closing operations of sterile products is limited and guidelines on the topic are very general. This article highlights the basic principles in sterile-product filling of syringes and vials. Also covered in this article are descriptions of some of the available devices for filling containers, a brief discussion of the advances in vial and syringe filling, a discussion on the advantages and disadvantages of sterile product filling methods, and a discussion on possible problems encountered during filling operations...
March 2017: International Journal of Pharmaceutical Compounding
https://www.readbyqxmd.com/read/28333673/choosing-a-vial-processing-line-for-aseptic-compounding-part-1
#19
Shaun Noorian, Navid Vahedi
Equipment systems that enable compliance with stringent state and federal compounding requirements are a topic of increasing interest to U.S. pharmacists. Of those equipment types, an aseptic vial processing line offers unique benefits (especially to 503B compounding pharmacies and small contract manufacturers of aseptic pilot-size batches) if the volume of sterile preparations dispensed offsets the cost of purchase, installation, and maintenance. In this article, the reasons for and the process of selecting an aseptic vial processing line for use in 2 independent 503B compounding pharmacies are presented, the operation of our choice of equipment is described, and specifications for the components of that line are listed...
July 2016: International Journal of Pharmaceutical Compounding
https://www.readbyqxmd.com/read/28333179/obtaining-antibiotics-online-from-within-the-uk-a-cross-sectional-study
#20
Sara Elizabeth Boyd, Luke Stephen Prockter Moore, Mark Gilchrist, Ceire Costelloe, Enrique Castro-Sánchez, Bryony Dean Franklin, Alison Helen Holmes
Background: Improved antibiotic stewardship (AS) and reduced prescribing in primary care, with a parallel increase in personal internet use, could lead citizens to obtain antibiotics from alternative sources online. Objectives: A cross-sectional analysis was performed to: (i) determine the quality and legality of online pharmacies selling antibiotics to the UK public; (ii) describe processes for obtaining antibiotics online from within the UK; and (iii) identify resulting AS and patient safety issues...
February 17, 2017: Journal of Antimicrobial Chemotherapy
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