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https://www.readbyqxmd.com/read/29352583/description-and-analysis-of-hospital-pharmacies-in-madagascar
#1
H R Ratsimbazafimahefa, F Sadeghipour, P Trouiller, A Pannatier, B Allenet
OBJECTIVE: Madagascar's health care system has operated without formal hospital pharmacies for more than two decades. The gradual integration of pharmacists in public hospitals since 2012 will allow the structuring of this field. This study was conducted to characterize the current situation regarding all aspects relating to the general functioning of hospital pharmacies and the services provided. METHODS: This qualitative research used semi-structured interviews...
January 15, 2018: Annales Pharmaceutiques Françaises
https://www.readbyqxmd.com/read/29280553/dapsone-for-topical-use-in-extemporaneous-preparations
#2
Johannes Wohlrab, Julia Michael
BACKGROUND: The sulfone dapsone has an established role in systemic therapy. Its pharmacological and toxicological properties are well known. Topically, dapsone is used in a gel formulation for the treatment of acne vulgaris. In addition, there have been individual case reports on the efficacy of topical dapsone preparations in the treatment of various neutrophilic dermatoses. To date, no finished medicinal product for topical use has been available in Germany. MATERIAL AND METHODS: Against this background, we set out to develop extemporaneous preparations containing dapsone (5 %) that meet the quality requirements of the European Pharmacopoeia as well as the manufacturing requirements of the German Ordinance on the Operation of Pharmacies (ApBetrO)...
December 27, 2017: Journal der Deutschen Dermatologischen Gesellschaft, Journal of the German Society of Dermatology: JDDG
https://www.readbyqxmd.com/read/29276300/multilayer-model-of-pharmacy-participation-in-the-antimicrobial-stewardship-program-at-a-large-academic-medical-center
#3
Yanina Dubrovskaya, Marco R Scipione, Justin Siegfried, Shin-Pung Jen, Vinh Pham, John Papadopoulos, Arnold Decano, Tyler Lewis, Arash Dabestani
Purpose: Leveraging pharmacy personnel resources for the purpose of antimicrobial stewardship program (ASP) operations presents a challenging task. We describe our experience integrating all pharmacists into an ASP, and evaluate the impact on ASP interventions, antimicrobial utilization, rate of selected hospital-onset infections and readmission. Summary: During a study period (January 1 to December 31, 2015), a total of 14 552 ASP-related pharmacy interventions were performed (ASP clinical pharmacotherapy specialists [CPS] n = 4025; non-ASP CPS n = 4888; hospital pharmacists n = 5639)...
October 2017: Hospital Pharmacy
https://www.readbyqxmd.com/read/29276292/formation-of-a-citywide-pharmacy-residents-collaborative-committee
#4
Jonathan H Sin, Jamie Chin, Loriel J Solodokin
Pharmacy residents undergo rigorous training to become skillful and knowledgeable independent practitioners. In addition to delivering direct clinical and operational pharmacy services, residents also participate in various administrative, educational, and scholarly activities as part of their residency experience. Throughout their training, residents may rely on individuals within their network for professional, personal, and emotional support, including residency program directors, preceptors, and co-residents from their respective institutions...
September 2017: Hospital Pharmacy
https://www.readbyqxmd.com/read/29274831/preoperative-cesarean-section-intravenous-acetaminophen-treatment-for-postoperative-pain-control-a-randomized-double-blinded-placebo-control-trial
#5
Craig V Towers, Sarah Shelton, Jaclyn van Nes, Emily Gregory, Emily Liske, Arion Smalley, Edward Mobley, Barbara Faircloth, Kim B Fortner
BACKGROUND: The United States currently has an opioid use disorder epidemic and research evaluating ways to minimize the use of opioids post-surgery are needed. One of these options is intravenous (IV) acetaminophen. If the use of preoperative IV acetaminophen was found to be effective for cesarean delivery, this would be beneficial for both the mother and breastfeeding neonate. OBJECTIVE: The primary study objective was to see if maternal opioid use was significantly less in the postoperative period for the study group that received 1 gram of IV acetaminophen preoperatively compared with a control group that received placebo...
December 21, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29248401/health-economic-implications-of-complications-associated-with-pancreaticoduodenectomy-at-a-university-hospital-a%C3%A2-retrospective-cohort-cost-study
#6
Jason Wang, Ronald Ma, Paul Eleftheriou, Leonid Churilov, David Debono, Ray Robbins, Mehrdad Nikfarjam, Chris Christophi, Laurence Weinberg
BACKGROUND: A cost analyses of complications following pancreaticoduodenectomy (PD) was performed in a high volume hepato-biliary-pancreatic service. We hypothesised that costs are increased with both severity and number of complications; we investigated the relationship between complications and specific cost centres. METHODS: 100 patients from 2011 to 2016 were included. Data relating to their perioperative course were collected. Complications were documented by the Clavien-Dindo classification and costs were inflated and converted to 2017 USD...
December 13, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/29248079/preliminary-findings-from-a-student-pharmacist-operated-transitions-of-care-pilot-service
#7
Kari Vavra, Matthew Paluzzi, Margaret de Voest, Sarah Raguckas, Martha Slot
BACKGROUND AND PURPOSE: Student pharmacists are well equipped to complete transitions of care (TOC) activities. This communication describes the implementation of a student-operated TOC pilot service at a community hospital and explores the clinical and educational findings of such a service. EDUCATIONAL ACTIVITY AND SETTING: Patients admitted to the hospital were included in the service if they had a primary care provider from an affiliated ambulatory care office...
January 2018: Currents in Pharmacy Teaching & Learning
https://www.readbyqxmd.com/read/29248068/measuring-social-science-concepts-in-pharmacy-education-research-from-definition-to-item-analysis-of-self-report-instruments
#8
REVIEW
M Ken Cor
MY ISSUE: Interpreting results from quantitative research can be difficult when measures of concepts are constructed poorly, something that can limit measurement validity. METHODS: Social science steps for defining concepts, guidelines for limiting construct-irrelevant variance when writing self-report questions, and techniques for conducting basic item analysis are reviewed to inform the design of instruments to measure social science concepts in pharmacy education research...
January 2018: Currents in Pharmacy Teaching & Learning
https://www.readbyqxmd.com/read/29239777/a-content-review-of-online-naloxone-continuing-education-courses-for-pharmacists-in-states-with-standing-orders
#9
Delesha M Carpenter, Courtney A Roberts, Salisa C Westrick, Stefanie P Ferreri, Korey A Kennelty, Kevin A Look, Olufunmilola Abraham, Courtenay Wilson
BACKGROUND: Many community pharmacists are uncomfortable educating patients about naloxone, an opioid reversal agent. OBJECTIVE: To examine whether training materials prepare pharmacists to counsel patients and caregivers about naloxone, online naloxone education materials for pharmacists in the 13 states with standing orders were analyzed. METHODS: Two coders reviewed 12 naloxone training programs and extracted data for 15 topics that were clustered in four categories: background/importance, naloxone products, business/operations, and communication...
November 21, 2017: Research in Social & Administrative Pharmacy: RSAP
https://www.readbyqxmd.com/read/29234498/evaluation-of-the-national-return-of-unwanted-medicines-rum-program-in-australia-a-study-protocol
#10
Amanda J Wheeler, Jean Spinks, Emilie Bettington, Fiona Kelly
Background: The National Return of Unwanted Medicines (NatRUM) program in Australia is one of the few nationally coordinated, free-to-consumer schemes to dispose of unwanted medicines globally. This scheme has been in operation since 1996, however, little is known about public awareness of the scheme and its effectiveness in reducing unsafe disposal practices. The study objectives are to undertake a review of (1) the current use of the NatRUM scheme by consumers; and (11) to investigate disposal practices and beliefs of the general population...
2017: Journal of Pharmaceutical Policy and Practice
https://www.readbyqxmd.com/read/29233445/entrepreneurship-skills-development-through-project-based-activity-in-bachelor-of-pharmacy-program
#11
Aliasgar Shahiwala
BACKGROUND AND PURPOSE: To provide pharmacy students with an opportunity to develop entrepreneurial thinking and skills. EDUCATIONAL ACTIVITY: A business proposal building project-based activity was integrated into a two-credit hour pharmacy management course during the eighth semester of the bachelor of pharmacy degree program. The student groups submitted their proposals, mimicking the process of submitting business proposals and obtaining approval in the real world...
July 2017: Currents in Pharmacy Teaching & Learning
https://www.readbyqxmd.com/read/29233383/implementation-of-a-pharmacy-research-committee-to-enhance-the-pharmacy-resident-research-experience
#12
Milena M McLaughlin, Elizabeth Short, Rachael Prusi, Dalila Masic, Noelle Rm Chapman, Michael Postelnick
BACKGROUND AND PURPOSE: Most postgraduate year 1 (PGY1) pharmacy residents complete at least one research project as part of their graduation requirements. The research skills learned prepare residents to address research questions and generate evidence-based recommendations for patient care. However, there are multiple steps involved in a research project, and streamlining this process can be difficult. EDUCATIONAL ACTIVITY AND SETTING: Northwestern Memorial Hospital (NMH), a large academic center located in Chicago, IL, developed a research committee (RC) to facilitate research within the department of pharmacy for residents and to maintain residency research support materials...
November 2017: Currents in Pharmacy Teaching & Learning
https://www.readbyqxmd.com/read/29233280/implementation-of-a-longitudinal-early-immersion-student-pharmacist-health-system-internship-program
#13
Lindsey B Amerine, John M Valgus, Joseph D Moore, Justin R Arnall, Scott W Savage
PURPOSE: The initiation, implementation, and benefits of a longitudinal early immersion student pharmacist health system internship are described. EDUCATIONAL ACTIVITY: A two-year longitudinal internship experience was implemented to provide exposure into distributional operations, direct patient care activities, and health-system pharmacy administration. The intent of the program was to create an opportunity for student pharmacists to enhance the quality of their education with practical experience by immersing them early in their careers within the healthcare system...
May 2017: Currents in Pharmacy Teaching & Learning
https://www.readbyqxmd.com/read/29222733/frail-older-people-with-multi-morbidities-in-primary-care-a-new-integrated-care-clinical-pharmacy-service
#14
Lelly Oboh, Catherine Leon, Sulman Qadir, Felicity Smith, Sally-Anne Francis
Background Older people confined to their own homes due to frailty, multiple longterm conditions and/or complex needs, are known to be at risk of medicines-related problems. Whilst a health and social care team approach to supporting these patients is advocated, there is limited evidence regarding how pharmacists can best contribute. Objective To describe a new specialist pharmacy service (called the integrated care clinical pharmacist) in terms of how it works, what it achieves and its policy implications...
December 8, 2017: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/29222365/implementation-of-an-integrated-pharmacy-supply-management-strategy
#15
Lindsey B Amerine, Daniel R Calvert, Ashley L Pappas, Sarah M Lee, John M Valgus, Scott W Savage
PURPOSE: Implementation of an integrated pharmacy supply management strategy is described. SUMMARY: In 2011, the formulary approval process and supply management for oncology medications were independent of each other at an oncology infusion center. Numerous nonformulary medications were kept on hand and reordered based on inventory levels that were established with inadequate usage information, while some formulary agents did not have on-hand inventory levels and had to be reordered on a patient-specific basis, which required paperwork and then a review by drug information staff per institutional policy...
December 15, 2017: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/29216613/documentation-records-and-reports
#16
Michael J Akers
This article deals with documentation to include the beginning of documentation, the requirements of Good Manufacturing Practice reports and records, and the steps that can be taken to minimize Good Manufacturing Practice documentation problems. It is important to remember that documentation for 503a compounding involves the Formulation Record, Compounding Record, Standard Operating Procedures, Safety Data Sheets, etc. For 503b outsourcing facilities, compliance with Current Good Manufacturing Practices is required, so this article is applicable to them...
September 2017: International Journal of Pharmaceutical Compounding
https://www.readbyqxmd.com/read/29202082/assessment-of-the-availability-and-rationality-of-unregistered-fixed-dose-drug-combinations-in-nepal-a-multicenter-cross-sectional-study
#17
Arjun Poudel, Mohamed Izham Mohamed Ibrahim, Pranaya Mishra, Subish Palaian
Background: The medications that are registered and available in a country are meant for the prevention and treatment of ailments and diseases. However, a lack of effective regulatory bodies and operative control mechanisms, especially in developing countries, promotes irrational and inappropriate use of medicines. This study aims to evaluate the availability and rationality of unregistered fixed-dose drug combinations (FDCs) in Nepal. Methods: A snowball sampling method with visits to 20 retail pharmacies in each of five major cities in Nepal was used to assess the availability of unregistered FDCs...
2017: Global Health Research and Policy
https://www.readbyqxmd.com/read/29193383/blood-transfusion-is-a-critical-determinant-of-resource-utilization-and-total-hospital-cost-in-liver-transplantation
#18
Jose Ruiz, Adam Dugan, Daniel L Davenport, Roberto Gedaly
OBJECTIVE: The aim of this study is to identify factors associated with increased resource use and total hospital cost after liver transplantation (LT). METHODS: A study of liver transplantation patients undergoing surgery between January 2008 to December 2013 was performed. Main end points were LOS, ICU LOS, days on the ventilator, total hospital costs (THC), service area costs. RESULTS: 191 patients undergoing LT were included in the analysis...
November 29, 2017: Clinical Transplantation
https://www.readbyqxmd.com/read/29172981/biosimilar-products-in-the-modern-u-s-health-care-and-regulatory-landscape
#19
Jesse Peterson, Holly Budlong, Tim Affeldt, Kyle Skiermont, Gregg Kyllo, Al Heaton
Biosimilars have the potential to greatly reduce medication costs in the United States. As of July 1, 2017, 5 biosimilars have been approved by the FDA, but only 2 are available for purchase. This commentary outlines the efforts of an integrated health system to ensure biosimilar accessibility and discusses the current challenges and future implications. We highlight the implementation of a health plan policy and how a health system's formulary committee can encourage use while considering provider perceptions and operational challenges...
December 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/29172974/following-the-biosimilar-breadcrumbs-when-health-systems-and-manufacturers-approach-forks-in-the-road
#20
Sonia T Oskouei
Over 2 years have passed since the first biosimilar was approved for use in the United States. Despite a relatively slow start, biosimilar activity has significantly increased in recent months. Biologics are the most expensive drug category in the United States, costing patients hundreds or even thousands of dollars per year. Biosimilars have the potential to significantly decrease cost of care, increase access, and improve patient outcomes. In order to realize the potential savings, biosimilar manufacturers, health care providers, and payers must develop strategies to navigate the challenging health care environment and understand where and how biosimilars bring the most value to patients...
December 2017: Journal of Managed Care & Specialty Pharmacy
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