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https://www.readbyqxmd.com/read/27821398/participation-of-a-coordinating-center-pharmacy-in-a-multicenter-international-study
#1
Jihyun Esther Jeon, Janet Mighty, Karen Lane, Nichol McBee, Ryan Majkowski, Steven Mayo, Daniel Hanley
PURPOSE: The activities of a coordinating center pharmacy (CCP) supporting a multicenter, international clinical trial are described. SUMMARY: Serving in a research support role comparable to that of a commercial clinical trial supply company, a CCP within the Johns Hopkins Hospital Investigational Drug Service (JHH IDS) uses its management expertise and infrastructure to support multicenter trials, such as the recently completed Clot Lysis: Evaluating Accelerated Resolution of Intraventricular Hemorrhage, Phase III (CLEAR III) trial...
November 15, 2016: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/27795775/-prioperative-adverse-events-critical-reading-of-the-data-registry-used-in-the-surgery-department-of-military-hospital-moulay-ismail-meknes
#2
Hicham Kechna, Omar Ouzzad, Khalid Chkoura, Jaouad Loutid, Moulay Ahmed Hachimi, Sidi Mohamed Hanafi
INTRODUCTION: Despite significant progress made in the field of safety in anesthesia, morbidity (serious or not, completely or partially related to anesthesia) remains common and no health practitioner is immune from accidents. In the current context where priority is given to training programmes, to quality and safety improvement in health care, the occurrence of an anesthesia-related accident in the surgery department is an extremely traumatic event. The fear of prosecution, the emotional context make it difficult to manage...
2016: Pan African Medical Journal
https://www.readbyqxmd.com/read/27785827/operational-and-clinical-strategies-to-address-drug-cost-containment-in-the-acute-care-setting
#3
Karen J McConnell, Oscar E Guzman, Nisha Pherwani, Dustin D Spencer, Jennifer D Van Cura, Katherine M Shea
OBJECTIVE: To provide clinical and operational strategies to generate drug cost savings in the hospital setting. METHODS: A search of the PubMed database was performed with no time limit through July 2016. All original prospective and retrospective studies, peer-reviewed guidelines, consensus statements, review articles, and accompanying references were evaluated for inclusion. Only articles published in the English language were included. MAIN RESULTS: Investigators reviewed 937 abstracts...
October 27, 2016: Pharmacotherapy
https://www.readbyqxmd.com/read/27771771/survival-after-intravenous-thrombin-prior-to-cardiopulmonary-bypass
#4
Vance G Nielsen, Samata R Paidy, Camron A Meek, Tiffany K Thornton, Scott D Lick
We present a case of a patient undergoing aortic valve replacement being inadvertently administered 5000 U of bovine thrombin instead of heparin for anticoagulation for cardiopulmonary bypass. The labeling error was made within the operating room pharmacy. The key to survival of this patient was a rapid diagnosis, administration of antithrombin and heparin, and removal of cardiac and great vessel thrombi. It is recommended that point of care anesthesia providers `prepare heparin for cardiopulmonary bypass anticoagulation, as thrombin is not used in anesthetic practice and is not contained within anesthesia cabinet medication drawers...
October 22, 2016: International Journal of Legal Medicine
https://www.readbyqxmd.com/read/27741501/using-administrative-data-to-identify-u-s-army-soldiers-at-high-risk-of-perpetrating-minor-violent-crimes
#5
Anthony J Rosellini, John Monahan, Amy E Street, Eric D Hill, Maria Petukhova, Ben Y Reis, Nancy A Sampson, David M Benedek, Paul Bliese, Murray B Stein, Robert J Ursano, Ronald C Kessler
Growing concerns exist about violent crimes perpetrated by U.S. military personnel. Although interventions exist to reduce violent crimes in high-risk populations, optimal implementation requires evidence-based targeting. The goal of the current study was to use machine learning methods (stepwise and penalized regression; random forests) to develop models to predict minor violent crime perpetration among U.S. Army soldiers. Predictors were abstracted from administrative data available for all 975,057 soldiers in the U...
January 2017: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/27717413/implementation-of-flu-vaccination-in-community-pharmacies-understanding-the-barriers-and-enablers
#6
C L Kirkdale, G Nebout, M Taitel, J Rubin, I Jacinto, R Horta, F Megerlin, T Thornley
Improving influenza vaccination coverage has been, and still remains a challenge internationally. There are now many examples where countries have pursued a pharmacist-led influenza vaccination service in order to enhance vaccination coverage of at-risk populations. England, Portugal and the United States are successful examples where their experience implementing this service can now be explored retrospectively and learnt from. This review aims to provide evidence to help overcome barriers to commissioning and implementation of such services in countries new to the experience...
October 4, 2016: Annales Pharmaceutiques Françaises
https://www.readbyqxmd.com/read/27698505/guidelines-for-the-establishment-of-appropriate-beyond-use-dating-of-sterile-compounded-admixtures
#7
Jamin Engel, Nicole Lazar
To support compounding of products that are sterile and chemically stable, beyond use dating of admixtures must include a thorough evaluation of appropriate resources. In most instances, resources provide documentation of a specific compounded admixture, at a specific concentration and storage parameters, that does not coincide with current operations or patient-specific requirements. To meet the operational demands of a pharmacy, institutions employ a referenced guideline approach to guide decision making for safe sterile admixing...
September 2016: Hospital Pharmacy
https://www.readbyqxmd.com/read/27697316/time-driven-activity-based-costing-to-identify-opportunities-for-cost-reduction-in-pediatric-appendectomy
#8
Yangyang R Yu, Paulette I Abbas, Carolyn M Smith, Kathleen E Carberry, Hui Ren, Binita Patel, Jed G Nuchtern, Monica E Lopez
PURPOSE: As reimbursement programs shift to value-based payment models emphasizing quality and efficient healthcare delivery, there exists a need to better understand process management to unearth true costs of patient care. We sought to identify cost-reduction opportunities in simple appendicitis management by applying a time-driven activity-based costing (TDABC) methodology to this high-volume surgical condition. METHODS: Process maps were created using medical record time stamps...
September 15, 2016: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/27686311/proton-pump-inhibitors-use-beware-of-side-effects
#9
Iftikhar Ahmad Asim Syed, Syed Hasan Abbas Naqvi
Proton pump inhibitors are most widely prescribed medicines all over the world. Since their introduction in pharmacy, life of millions of people has changed completely. Their ability to inhibit acid secretion in stomach has changed the natural history of many once-dreaded conditions like peptic ulcer and gastroesophageal reflux disease. Operation like gastrectomy and partial gastrectomy are carried out very rarely. These medicines are considered very cost-effective, have excellent safety profile, and provide prompt symptomatic relief...
October 2016: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/27649748/impact-of-hurricane-sandy-on-community-pharmacies-in-severely-affected-areas-of-new-york-city-a-qualitative-assessment
#10
Vibhuti Arya, Eric Medina, Allison Scaccia, Cathleen Mathew, David Starr
Hurricane Sandy was one of the most severe natural disasters to hit the Mid-Atlantic States in recent history. Community pharmacies were among the businesses affected, with flooding and power outages significantly reducing services offered by many pharmacies. The objectives of our study were to assess the impact of Hurricane Sandy on community pharmacies, both independently owned and chain, in the severely affected areas of New York City (NYC), including Coney Island, Staten Island, and the Rockaways, using qualitative methods, and propose strategies to mitigate the impact of future storms and disasters...
January 2016: American Journal of Disaster Medicine
https://www.readbyqxmd.com/read/27582674/a-cluster-of-presumed-noninfectious-endophthalmitis-after-intravitreal-injection-of-bevacizumab-long-term-follow-up
#11
Federico Ricci, Antonio Calabrese, Cecilia De Felici, Filippo Missiroli, Marco Pileri, Federico Regine
PURPOSE: To report the outcome of 5 consecutive cases of presumed, noninfectious endopththalmitis following intravitreal injection of bevacizumab (IVB). METHODS: Ten pre-loaded syringes of bevacizumab (1.25 mg/50 µL) furnished by a compounding pharmacy were injected intravitreally. Treatments were performed in the operating room by the same surgeon on 2 consecutive days. RESULTS: Of 10 eyes, 5 showed moderate to severe ocular inflammation within a few days of injection...
2016: Digital Journal of Ophthalmology: DJO
https://www.readbyqxmd.com/read/27580822/wait-and-consult-times-for-primary-healthcare-services-in-central-mozambique-a-time-motion-study
#12
Bradley H Wagenaar, Sarah Gimbel, Roxanne Hoek, James Pfeiffer, Cathy Michel, Fatima Cuembelo, Titos Quembo, Pires Afonso, Stephen Gloyd, Barrot H Lambdin, Mark A Micek, Victoria Porthé, Kenneth Sherr
BACKGROUND: We describe wait and consult times across public-sector clinics and identify health facility determinants of wait and consult times. DESIGN: We observed 8,102 patient arrivals and departures from clinical service areas across 12 public-sector clinics in Sofala and Manica Provinces between January and April 2011. Negative binomial generalized estimating equations were used to model associated health facility factors. RESULTS: Mean wait times (in minutes) were: 26...
2016: Global Health Action
https://www.readbyqxmd.com/read/27579828/pharmacy-benefits-management-in-the-veterans-health-administration-revisited-a-decade-of-advancements-2004-2014
#13
Sherrie L Aspinall, Mariscelle M Sales, Chester B Good, Vincent Calabrese, Peter A Glassman, Muriel Burk, Von R Moore, Melinda M Neuhauser, Lori Golterman, Heather Ourth, Michael A Valentino, Francesca E Cunningham
UNLABELLED: Over the past decade, the Department of Veterans Affairs (VA) Pharmacy Benefits Management Services (PBM) has enhanced its formulary management activities and added programs to ensure that the national drug plan continues to meet the pharmacy needs of veterans and to promote safe and appropriate drug therapy in the face of rising medication expenditures. This article describes the broad range of services provided by the VA PBM that work in partnership to deliver a high-quality and sustainable pharmacy benefit for veterans...
September 2016: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/27574748/pharmacy-benefits-management-in-the-veterans-health-administration-revisited-a-decade-of-advancements-2004-2014
#14
Sherrie L Aspinall, Mariscelle M Sales, Chester B Good, Vincent Calabrese, Peter A Glassman, Muriel Burk, Von R Moore, Melinda M Neuhauser, Lori Golterman, Heather Ourth, Michael A Valentino, Francesca E Cunningham
UNLABELLED: Over the past decade, the Department of Veterans Affairs (VA) Pharmacy Benefits Management Services (PBM) has enhanced its formulary management activities and added programs to ensure that the national drug plan continues to meet the pharmacy needs of veterans and to promote safe and appropriate drug therapy in the face of rising medication expenditures. This article describes the broad range of services provided by the VA PBM that work in partnership to deliver a high-quality and sustainable pharmacy benefit for veterans...
September 2016: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/27573334/skills-and-knowledge-of-informatics-and-training-needs-of-hospital-pharmacists-in-thailand-a-self-assessment-survey
#15
Teeraporn Chonsilapawit, Suang Rungpragayphan
OBJECTIVE: Because hospital pharmacists have to deal with large amounts of health information and advanced information technology in practice, they must possess adequate skills and knowledge of informatics to operate efficiently. However, most current pharmacy curricula in Thailand barely address the principles and skills concerned with informatics, and Thai pharmacists usually acquire computer literacy and informatics skills through personal-interest training and self-study. In this study, we aimed to assess the skills and knowledge of informatics and the training needs of hospital pharmacists in Thailand, in order to improve curricular and professional development...
October 2016: International Journal of Medical Informatics
https://www.readbyqxmd.com/read/27562631/qualitative-study-on-the-implementation-of-professional-pharmacy-services-in-australian-community-pharmacies-using-framework-analysis
#16
Joanna C Moullin, Daniel Sabater-Hernández, Shalom I Benrimoj
BACKGROUND: Multiple studies have explored the implementation process and influences, however it appears there is no study investigating these influences across the stages of implementation. Community pharmacy is attempting to implement professional services (pharmaceutical care and other health services). The use of implementation theory may assist the achievement of widespread provision, support and integration. The objective was to investigate professional service implementation in community pharmacy to contextualise and advance the concepts of a generic implementation framework previously published...
2016: BMC Health Services Research
https://www.readbyqxmd.com/read/27559194/big-data-implications-for-health-system-pharmacy
#17
Laura B Stokes, Joseph W Rogers, John B Hertig, Robert J Weber
Big Data refers to datasets that are so large and complex that traditional methods and hardware for collecting, sharing, and analyzing them are not possible. Big Data that is accurate leads to more confident decision making, improved operational efficiency, and reduced costs. The rapid growth of health care information results in Big Data around health services, treatments, and outcomes, and Big Data can be used to analyze the benefit of health system pharmacy services. The goal of this article is to provide a perspective on how Big Data can be applied to health system pharmacy...
July 2016: Hospital Pharmacy
https://www.readbyqxmd.com/read/27544712/predictive-properties-of-the-asthma-control-test-and-its-component-questions-for-severe-asthma-exacerbations
#18
Sonia Cajigal, Karen E Wells, Edward L Peterson, Brian K Ahmedani, James J Yang, Rajesh Kumar, Esteban G Burchard, L Keoki Williams
BACKGROUND: Current US guidelines recommend the Asthma Control Test (ACT) for assessing disease control and selecting treatment. OBJECTIVE: The goal of this study was to prospectively assess the ACT and its component questions for their utility in predicting the risk of severe asthma exacerbations. METHODS: Individuals were participants in the Study of Asthma Phenotypes and Pharmacogenomic Interactions by Race-Ethnicity, and those included in the current analysis had the following characteristics: age 18 years or more, physician-diagnosed asthma, and longitudinal care received at a large health system in southeastern Michigan...
August 17, 2016: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/27540257/paediatric-standardised-concentration-infusions-a-national-solution
#19
Moninne Howlett, Michael Curtin, Dermot Doherty, Paula Gleeson, Michelle Sheerin, Cormac Breatnach
AIM: Wide scale implementation of paediatric standardised concentration infusions (SCIs) and the use of smart pump technology has been slow despite international safety agency recommendations. Implementation rates in European hospitals fall far below those in the United States, where for the last decade accreditation has been linked to implementation.1 2 Multidisciplinary collaboration is essential, with pharmacy input and the creation of a smart pump drug library recognised as often being limiting, yet crucial factors, to implementation...
September 2016: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/27540250/an-audit-to-assess-the-timings-of-ttas-and-inpatient-orders-in-paediatrics-from-writing-to-screening-to-dispensing-and-to-leaving-dispensary
#20
Ami Hale, Nanna Christiansen, Heather Calvert
AIM: To assess the time it takes for paediatric TTA and inpatient orders to be dispensed and sent to ward. This is to establish if the Trust is meeting an operational Key Performance Indicator (KPI). STANDARDS KPIS: ▸ 85% of urgent items (TTAs) dispensed within 1 hour.▸ 85% of non-urgent items (most inpatient orders) dispensed within 3 hrs. METHOD: To audit the time it takes for TTAs and inpatient orders to be screened, sent to dispensary, labelled, dispensed, checked, and leave dispensary...
September 2016: Archives of Disease in Childhood
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