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https://www.readbyqxmd.com/read/29156863/sleep-quality-sleeping-postures-and-sleeping-equipment-in-patients-with-ankylosing-spondylitis
#1
Servet Yolbaş, Ahmet Yıldırım, Deccane Düzenci, Barış Gündoğdu, Metin Özgen, Süleyman Serdar Koca
Background/aim: Inflammatory back pain, spinal stiffness, and limited spinal mobility are characteristic features of ankylosing spondylitis (AS). Sleeping postures can affect and/or reflect sleeping disturbances. The aim of the study was to evaluate sleeping postures and sleep disturbances in patients with AS. Materials and methods: Seventy-seven patients with AS and 49 healthy controls were enrolled. The Pittsburgh Sleep Quality Index (PSQI) and the Insomnia Severity Index (ISI) were applied to both groups...
August 23, 2017: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/29156650/nondestructive-evaluation-of-carbon-fiber-bicycle-frames-using-infrared-thermography
#2
Rubén Usamentiaga, Clemente Ibarra-Castanedo, Matthieu Klein, Xavier Maldague, Jeroen Peeters, Alvaro Sanchez-Beato
Bicycle frames made of carbon fibre are extremely popular for high-performance cycling due to the stiffness-to-weight ratio, which enables greater power transfer. However, products manufactured using carbon fibre are sensitive to impact damage. Therefore, intelligent nondestructive evaluation is a required step to prevent failures and ensure a secure usage of the bicycle. This work proposes an inspection method based on active thermography, a proven technique successfully applied to other materials. Different configurations for the inspection are tested, including power and heating time...
November 20, 2017: Sensors
https://www.readbyqxmd.com/read/29156422/syndecan-1-in-mechanosensing-of-nanotopological-cues-in-engineered-materials
#3
Victoria Le, Jason Lee, Somali Chaterji, Adrianne Spencer, Yen-Liang Liu, Peter Kim, Hsin-Chih Yeh, Deok-Ho Kim, Aaron B Baker
The cells of the vascular system are highly sensitive to biophysical cues from their local cellular microenvironment. To engineer improved materials for vascular devices and delivery of cell therapies, a key challenge is to understand the mechanisms that cells use to sense biophysical cues from their environment. Syndecans are heparan sulfate proteoglycans (HSPGs) that consist of a protein core modified with heparan sulfate glycosaminoglycan chains. Due to their presence on the cell surface and their interaction with cytoskeletal and focal adhesion associated molecules, cell surface proteoglycans are well poised to serve as mechanosensors of the cellular microenvironment...
November 9, 2017: Biomaterials
https://www.readbyqxmd.com/read/29156354/anisotropic-and-nonlinear-biaxial-mechanical-response-of-porcine-small-bowel-mesentery
#4
Keyvan Amini Khoiy, Sophia Abdulhai, Ian C Glenn, Todd A Ponsky, Rouzbeh Amini
Intestinal malrotation places pediatric patients at the risk of midgut volvulus, a complication that can lead to ischemic bowel, short gut syndrome, and even death. Even though the treatments for symptomatic patients of this complication are clear, it is still a challenge to identify asymptomatic patients who are at a higher risk of midgut volvulus and decide on a suitable course of treatment. Development of an accurate computerized model of this intestinal abnormality could help in gaining a better understanding of its integral behavior...
November 11, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/29156068/lmwf-5a-for-the-treatment-of-severe-osteoarthritis-of-the-knee-integrated-analysis-of-safety-and-efficacy
#5
Brian Cole, Brian McGrath, Kristin Salottolo, David Bar-Or
The low-molecular-weight fraction of 5% human serum albumin (LMWF-5A) is being developed to treat the signs and symptoms of severe osteoarthritis of the knee. This study was a post hoc pooled analysis of 3 randomized placebo-controlled trials of a single intra-articular injection of LMWF-5A, focusing on the subset of patients with severe osteoarthritis of the knee (Kellgren-Lawrence grade 4). Patients were randomized 1:1 to receive a single 4-mL intra-articular knee injection of either LMWF-5A or saline. Safety was assessed as the incidence and severity of adverse events...
November 20, 2017: Orthopedics
https://www.readbyqxmd.com/read/29155890/longitudinal-fasting-blood-glucose-patterns-and-arterial-stiffness-risk-in-a-population-without-diabetes
#6
Yuntao Wu, Junxing Yu, Cheng Jin, Yun Li, Jinmei Su, Guoqing Wei, Xiaoming Zheng, Jingsheng Gao, Wenyuan Gao, Shouling Wu
OBJECTIVE: To identify long-term fasting blood glucose trajectories and to assess the association between the trajectories and the risk of arterial stiffness in individuals without diabetes. METHODS: We enrolled 16,454 non-diabetic participants from Kailuan cohort. Fasting blood glucose concentrations were measured in 2006, 2008, and 2010 survey. Brachial-ankle pulse wave velocities were measured during 2011 to 2016. Multivariate regression model was used to estimate the difference of brachial-ankle pulse wave velocity levels and logistic regression was used to calculate odds ratios (ORs) and 95% confidence intervals (95%CIs) of arterial stiffness risk, according to the fasting blood glucose trajectories...
2017: PloS One
https://www.readbyqxmd.com/read/29155842/posterior-column-acetabular-fracture-fixation-using-a-w-shaped-angular-plate-a-biomechanical-analysis
#7
Ke Su, Song Liu, Tao Wu, Yingchao Yin, Ruipeng Zhang, Shilun Li, Yingze Zhang
OBJECTIVE: The purpose of this study was to compare the stability and feasibility of four fixation constructs in a posterior column acetabular fracture: one reconstruction plate, one reconstruction plate and lag screw, two reconstruction plates, and a W-shaped acetabular angular plate. METHODS: Twenty embalmed cadaveric pelvises with a posterior column acetabular fractures were allocated to one of four groups: 1) a reconstruction plate, 2) a reconstruction plate with a posterior column lag screw, 3) double reconstruction plates, and 4) a W-shaped acetabular angular plate...
2017: PloS One
https://www.readbyqxmd.com/read/29155710/dna-nanotubes-as-a-versatile-tool-to-study-semiflexible-polymers
#8
Jörg Schnauß, Martin Glaser, Jessica S Lorenz, Carsten Schuldt, Christin Möser, Martin Sajfutdinow, Tina Händler, Josef A Käs, David M Smith
Mechanical properties of complex, polymer-based soft matter, such as cells or biopolymer networks, can be understood in neither the classical frame of flexible polymers nor of rigid rods. Underlying filaments remain outstretched due to their non-vanishing backbone stiffness, which is quantified via the persistence length (lp), but they are also subject to strong thermal fluctuations. Their finite bending stiffness leads to unique, non-trivial collective mechanics of bulk networks, enabling the formation of stable scaffolds at low volume fractions while providing large mesh sizes...
October 25, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/29155311/glenoid-exposure-in-total-shoulder-arthroplasty
#9
REVIEW
L Nové-Josserand, P Clavert
Glenoid exposure is agreed to be a difficult step, but is also a key step in total shoulder arthroplasty, both anatomic and reverse. It conditions unhindered use of the ancillary instrumentation and thus correct glenoid component positioning. The main stages comprise arthrotomy, by opening the rotator cuff, humeral head cut, and inferior glenohumeral release, enabling shifting of the humerus and good exposure of the glenoid cavity. The two main approaches are deltopectoral and anterosuperior transdeltoid. Using the deltopectoral approach, arthrotomy is performed through the subscapularis muscle, by various techniques...
November 16, 2017: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/29155132/stiffening-of-flexible-sumo1-protein-upon-peptide-binding-analysis-with-anisotropic-network-model
#10
Ranja Sarkar
SUMO (small ubiquitin-like modifier) proteins interact with a large number of target proteins via a key regulatory event called sumoylation that encompasses activation, conjugation and ligation of SUMO proteins through specific E1, E2, and E3-type enzymes respectively. Single-molecule atomic force microscopic (AFM) experiments performed to unravel bound SUMO1 along its N-C termini direction reveal that E3-ligases (in the form of small peptides) increase mechanical stability (along the axis) of the flexible protein upon binding...
November 16, 2017: Mathematical Biosciences
https://www.readbyqxmd.com/read/29154969/adults-with-cystic-fibrosis-have-deficits-in-bone-structure-and-strength-at-the-distal-tibia-despite-similar-size-and-measuring-standard-and-relative-sites
#11
Kyle K Nishiyama, Sanchita Agarwal, Anna Kepley, Fernando Rosete, Yizhong Hu, X Edward Guo, Claire L Keating, Emily A DiMango, Elizabeth Shane
Individuals with cystic fibrosis (CF) have lower bone mineral density (BMD) by DXA and are at higher risk of fracture than healthy controls. However, the 2-dimensional measurement of areal BMD (aBMD) provided by DXA is influenced by bone size and the true extent of the bone deficit is unclear. Our objective was to use high-resolution peripheral quantitative computed tomography (HR-pQCT) and individual trabecula segmentation (ITS) analysis to compare volumetric BMD (vBMD), microarchitecture and estimated strength at the distal radius and tibia in 26 young adults with CF and 26 controls matched for age, gender, and race...
November 14, 2017: Bone
https://www.readbyqxmd.com/read/29154683/arterial-stiffness-in-childhood-a-predictor-for-later-cardiovascular-disease
#12
Fariba Ahmadizar, Trudy Voortman
No abstract text is available yet for this article.
January 1, 2017: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/29154389/latent-autoimmune-diabetes-and-limbic-encephalitis-with-antibodies-against-glutamic-acid-decarboxylase
#13
Stoyan Popkirov, Seena Sebastian, Fatme Seval Ismail, Jörg Wellmer
Antibodies against glutamic acid decarboxylase (GAD) are a hallmark of type 1 diabetes and its late-onset variant, latent autoimmune diabetes of the adult (LADA).(1) While cerebrovascular disease and dementia are common causes of cognitive dysfunction and neurological deficits in diabetic patients,(2,3) rare autoimmune disorders of the central nervous system such as stiff-person syndrom or limbic encephalits can also occur on the basis of shared GAD autoimmunity.(4,5).
November 20, 2017: Journal of Diabetes
https://www.readbyqxmd.com/read/29154300/fracture-generation-in-human-vertebrae-under-compression-loading-the-influence-of-pedicle-preservation-and-bone-mineral-density-on-in-vitro-fracture-behavior
#14
Michael Kraxenberger, Christian Schröder, Tobias Geith, Andreas Büttner, Christoph von SchulzePeelengahr, Christof Birkenmaier, Peter Muller, Volkmar Jansson, Bernd Wegener
BACKGROUND: Fractured vertebral bodies are a common and wide spread health issue. OBJECTIVE: The purpose of this study was to develop a standardized method to experimentally generate compression fractures in vertebral bodies. The influence of the pedicles has been investigated with regards to the fracture behavior. The correlation between bone mineral density (BMD), the cause of fractures and the fracture behavior was investigated. METHODS: Twenty-one fresh frozen human lumbar spines were examined for bone mineral density (BMD) by means of quantitative computed tomography (qCT)...
November 10, 2017: Technology and Health Care: Official Journal of the European Society for Engineering and Medicine
https://www.readbyqxmd.com/read/29154065/does-nurses-role-health-or-symptoms-influence-their-personal-use-of-ingestible-complementary-and-alternative-medicines
#15
Sofia Dimitrelis, Lin Perry, Robyn Gallagher, Christine Duffield, David Sibbritt, Rachel Nicholls, Xiaoyue Xu
OBJECTIVES: To investigate the influence of work-related characteristics, health, health behaviours and symptoms on ingestible biologically-based Complementary and Alternative Medicine (CAM) use within the Australian nursing and midwifery workforce. BACKGROUND: CAM use is widespread worldwide, but there is little research into nurses' and midwives' personal use of ingestible CAM in Australia. METHODS: An online survey in 2014-15 used validated instruments and items to examine use of ingestible biologically-based CAM (herbs, foods and vitamins, minerals, amino acids, enzymes and other supplements), and the health and work-related characteristics of 5041 nurses and midwives recruited through the New South Wales Nurses and Midwives Association and professional networks...
December 2017: Complementary Therapies in Medicine
https://www.readbyqxmd.com/read/29153707/the-influence-of-muscle-activation-on-impact-dynamics-during-lateral-falls-on-the-hip
#16
Daniel R Martel, Iris C Levine, Steven P Pretty, Andrew C Laing
Muscle activation has been demonstrated to influence impact dynamics during scenarios including running, automotive impacts, and head impacts. This study investigated the effects of targeted muscle activation magnitude on impact dynamics during low energy falls on the hip with human volunteers. Fifteen university-aged participants (eight females, seven males) underwent 12 lateral pelvis release trials. Half of the trials were muscle-'relaxed'; in the remaining 'contracted' trials participants isometrically contracted their gluteus medius to 20-30% of maximal voluntary contraction before the drop was initiated onto a force plate...
November 10, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/29153673/pregnancy-complications-and-later-vascular-ultrasound-measures-a-cohort-study
#17
Emily W Harville, Markus Juonala, Jorma S A Viikari, Mika Kähönen, Olli T Raitakari
OBJECTIVES: Pregnancy complications predict or even predispose to later cardiovascular disease in the mother. We examined whether pregnancy complications are associated with post-pregnancy measures of endothelial dysfunction and arterial stiffness. STUDY DESIGN: Prospective cohort; Data for 847 women female participants in the Cardiovascular Risk in Young Finns study were linked with the national birth registry. Preterm birth (<37weeks), low birthweight (<2500g), small-for-gestational-age (weight <10th percentile for gestational age), and hypertensive disorders of pregnancy were examined as predictors of later vascular measures...
October 2017: Pregnancy Hypertension
https://www.readbyqxmd.com/read/29153463/late-normal-tissue-effects-in-the-arm-and-shoulder-following-lymphatic-radiotherapy-results-from-the-uk-start-standardisation-of-breast-radiotherapy-trials
#18
Joanne S Haviland, Mariella Mannino, Clare Griffin, Nuria Porta, Mark Sydenham, Judith M Bliss, John R Yarnold
BACKGROUND AND PURPOSE: Adjuvant lymphatic radiotherapy (LNRT) is recommended for selected axillary node positive women with early breast cancer. We investigated whether hypofractionated LNRT is safe combined with similarly-hypofractionated breast/chest wall radiotherapy (RT). MATERIAL AND METHODS: The Standardisation of Breast Radiotherapy (START) pilot, A and B trials randomised women with early breast cancer to schedules of 2.67-3.3 Gy versus 2.0 Gy fractions (control)...
November 15, 2017: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/29153367/real-time-two-dimensional-shear-wave-elastography-for-liver-stiffness-in-children-interobserver-variation-and-effect-of-breathing-technique
#19
Hee Mang Yoon, Young Ah Cho, Jeong Rye Kim, Seung Soo Lee, Ah Young Jung, Jin Seong Lee, Seak Hee Oh, Kyung Mo Kim
OBJECTIVES: To evaluate interobserver variation and to assess the effect of the breathing technique on liver stiffness (LS) measurement using real-time two-dimensional shear-wave elastography (2D-SWE) in children. METHODS: Patients who underwent real-time 2D-SWE by two operators (group 1) and patients who underwent real-time 2D-SWE by one operator using the free-breathing and breath-holding techniques (group 2) were included. In group 1, interobserver agreement was assessed using the intraclass correlation coefficient (ICC) and the 95% limits-of-agreement was analyzed to evaluate the maximum change in the LS values based on Bland-Altman analysis...
December 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/29153362/in-vivo-assessment-of-placental-elasticity-in-intrauterine-growth-restriction-by-shear-wave-elastography
#20
Hatice Arioz Habibi, Ebru Alici Davutoglu, Sedat Giray Kandemirli, Mine Aslan, Aysegul Ozel, Ayse Kalyoncu Ucar, Pinar Zeytun, Riza Madazli, Ibrahim Adaletli
PURPOSE: In this study, we evaluated the placental elasticity in vivo by shear-wave elastography in pregnant women under follow-up for intrauterine growth restriction (IUGR) and compared the elasticity values to normal pregnancies. MATERIAL AND METHODS: This prospective study included 42 pregnant women with a possible diagnosis of intrauterine growth restriction based on obstetrical grayscale and Doppler ultrasonography and 42 women with a normal pregnancy during the 2nd and 3rd trimester...
December 2017: European Journal of Radiology
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