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https://www.readbyqxmd.com/read/28306707/severity-of-illness-index-for-surgical-departments-in-a-cuban-hospital-a-revalidation-study
#1
Amadys Armas-Bencomo, Teddy Osmin Tamargo-Barbeito, Edelberto Fuentes-Valdés, Rosa Eugenia Jiménez-Paneque
INTRODUCTION: In the context of the evaluation of hospital services, the incorporation of severity indices allows an essential control variable for performance comparisons in time and space through risk adjustment. The severity index for surgical services was developed in 1999 and validated as a general index for surgical services. Sixteen years later the hospital context is different in many ways and a revalidation was considered necessary to guarantee its current usefulness. OBJECTIVE: To evaluate the validity and reliability of the surgical services severity index to warrant its reasonable use under current conditions...
March 8, 2017: Medwave
https://www.readbyqxmd.com/read/28274186/cochlear-implantation-under-local-anaesthesia-our-experience-and-a-validated-patient-satisfaction-questionnaire
#2
Sandeep G Mistry, Simon Carr, Jane Martin, David R Strachan, Christopher H Raine, Georgios Fyrmpas
OBJECTIVES: Cochlear implantation (CI) under local anaesthetic (LA) has previously been shown to be a successful and safe option for a specific group of patients (e.g. elderly and significant co-morbidity). We aim to discuss our practice and obtain qualitative information about patient experience from our cohort of patients at the Yorkshire Auditory Implant Service (YAIS). METHODS: Retrospective chart review to include demographics, co-morbidities and physiological parameters were recorded and used to calculate P-POSSUM (Portsmouth Physiological and Operative Severity Score for the enumeration of Mortality and Morbidity) scores...
March 9, 2017: Cochlear Implants International
https://www.readbyqxmd.com/read/28256396/adjusted-hospital-outcomes-of-abdominal-aortic-aneurysm-surgery-reported-in-the-dutch-surgical-aneurysm-audit
#3
N Lijftogt, A C Vahl, E D Wilschut, B H P Elsman, S Amodio, E W van Zwet, V J Leijdekkers, M W J M Wouters, J F Hamming
OBJECTIVE/BACKGROUND: The Dutch Surgical Aneurysm Audit (DSAA) is mandatory for all patients with primary abdominal aortic aneurysms (AAAs) in the Netherlands. The aims are to present the observed outcomes of AAA surgery against the predicted outcomes by means of V-POSSUM (Vascular-Physiological and Operative Severity Score for the enUmeration of Mortality and Morbidity). Adjusted mortality was calculated by the original and re-estimated V(physiology)-POSSUM for hospital comparisons. METHODS: All patients operated on from January 2013 to December 2014 were included for analysis...
February 28, 2017: European Journal of Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/28250670/portsmouth-physiological-and-operative-severity-score-for-the-enumeration-of-mortality-and-morbidity-scoring-system-in-general-surgical-practice-and-identifying-risk-factors-for-poor-outcome
#4
Ashish Tyagi, Nitin Nagpal, D S Sidhu, Amandeep Singh, Anjali Tyagi
BACKGROUND: Estimation of the outcome is paramount in disease stratification and subsequent management in severely ill surgical patients. Risk scoring helps us quantify the prospects of adverse outcome in a patient. Portsmouth-Physiological and Operative Severity Score for the Enumeration of Mortality and Morbidity (P-POSSUM) the world over has proved itself as a worthy scoring system and the present study was done to evaluate the feasibility of P-POSSUM as a risk scoring system as a tool in efficacious prediction of mortality and morbidity in our demographic profile...
January 2017: Journal of Natural Science, Biology, and Medicine
https://www.readbyqxmd.com/read/28247055/camp-dependent-secretagogues-stimulate-the-nahco3-cotransporter-in-the-villous-epithelium-of-the-brushtail-possum-trichosurus-vulpecula
#5
Pin-Chun Chao, A Grant Butt
In the ileum of the brushtail possum, Trichosurus vulpecula, fluid secretion appears to be driven by electrogenic HCO3(-) secretion. Consistent with this, the cystic fibrosis transmembrane conductance regulator is expressed in the apical membrane of the ileal epithelial cells and the pancreatic or secretory variant of the NaHCO3 cotransporter in the basolateral membrane. This suggests that in the possum ileum, electrogenic HCO3(-) secretion is driven by basolateral NaHCO3 cotransporter (NBC) activity. To determine if the NBC contributes to HCO3(-) secretion in the possum ileum, intracellular pH (pHi) measurements in isolated villi were used to demonstrate NBC activity in the ileal epithelial cells and investigate the effect of cAMP-dependent secretagogues...
February 28, 2017: Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology
https://www.readbyqxmd.com/read/28243006/audit-of-preoperative-fluid-resuscitation-in-perforation-peritonitis-patients-using-physiological-and-operative-severity-score-for-enumeration-of-mortality-and-morbidity
#6
Sunil Kumar
CONTEXT: Debate continues regarding fluid (crystalloid vs. colloid) of choice for resuscitation. Physiological and Operative Severity Score for enUmeration of Mortality and Morbidity (POSSUM) may be used to compare the benefits of preoperative fluid resuscitation with crystalloids and colloids in peritonitis patients. AIMS: The aim of this study is to compare crystalloid and colloid for preoperative resuscitation using morbidity, mortality, length of hospital stay (LOS), and time taken to resuscitate as the outcome parameters...
January 2017: Journal of Emergencies, Trauma, and Shock
https://www.readbyqxmd.com/read/28226343/-diagnosis-and-risk-assessment-of-postoperative-complications-of-gastric-cancer-in-japan-and-korea
#7
Xiang Hu, Chi Zhang
Radical surgery of gastric cancer (D2 lymph node dissection) as the standard operation is widely used in clinical practice and satisfactory prognosis can be obtained in patients who receive radical gastrectomy. But surgical invasion can cause high morbidity of complications and mortality. The data of large-scale evidence-based medical clinical trials and large databases in Japan and Korea showed that anastomotic leakage, pancreatic leakage and abdominal abscess were the most common complications after gastrectomy, and the morbidity of complication was about 20% and mortality was about 1%...
February 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/28209138/using-whole-genome-sequencing-to-investigate-transmission-in-a-multi-host-system-bovine-tuberculosis-in-new-zealand
#8
Joseph Crispell, Ruth N Zadoks, Simon R Harris, Brent Paterson, Desmond M Collins, Geoffrey W de-Lisle, Paul Livingstone, Mark A Neill, Roman Biek, Samantha J Lycett, Rowland R Kao, Marian Price-Carter
BACKGROUND: Bovine tuberculosis (bTB), caused by Mycobacterium bovis, is an important livestock disease raising public health and economic concerns around the world. In New Zealand, a number of wildlife species are implicated in the spread and persistence of bTB in cattle populations, most notably the brushtail possum (Trichosurus vulpecula). Whole Genome Sequenced (WGS) M. bovis isolates sourced from infected cattle and wildlife across New Zealand were analysed. Bayesian phylogenetic analyses were conducted to estimate the substitution rate of the sampled population and investigate the role of wildlife...
February 16, 2017: BMC Genomics
https://www.readbyqxmd.com/read/28194619/how-herbivore-browsing-strategy-affects-whole-plant-photosynthetic-capacity
#9
E Penelope Holland, Julie Mugford, Rachelle N Binny, Alex James
If a browse damage index indicates that a tree has been 50% browsed by herbivores, does this mean half the leaves are entirely eaten or are all the leaves half eaten? Were the affected leaves old or young? Large or small? In sunshine or shade? Understanding what effect browsing will have on the photosynthetic capacity and the plant's survival ability clearly requires a greater understanding of browsing strategy across the canopy than can be given by a single index value. We developed stochastic models of leaf production, growth and consumption using data from kamahi (Weinmannia racemosa) trees in New Zealand which have been browsed by possums (Trichosurus vulpecula), to ascertain which of six feasible browsing strategies possums are most likely to be employing...
February 13, 2017: Bulletin of Mathematical Biology
https://www.readbyqxmd.com/read/28173840/morphological-and-molecular-description-of-ixodes-woyliei-n-sp-ixodidae-with-consideration-for-co-extinction-with-its-critically-endangered-marsupial-host
#10
Amanda Ash, Aileen Elliot, Stephanie Godfrey, Halina Burmej, Mohammad Yazid Abdad, Amy Northover, Adrian Wayne, Keith Morris, Peta Clode, Alan Lymbery, R C Andrew Thompson
BACKGROUND: Taxonomic identification of ticks obtained during a longitudinal survey of the critically endangered marsupial, Bettongia penicillata Gray, 1837 (woylie, brush-tailed bettong) revealed a new species of Ixodes Latrielle, 1795. Here we provide morphological data for the female and nymphal life stages of this novel species (Ixodes woyliei n. sp.), in combination with molecular characterisation using the mitochondrial cytochrome c oxidase subunit 1 gene (cox1). In addition, molecular characterisation was conducted on several described Ixodes species and used to provide phylogenetic context...
February 7, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/28133047/-risk-evaluation-and-prognostic-prediction-of-colorectal-cancer-in-elderly-patients-over-80-years-of-age
#11
Shinji Ohki, Koji Kase, Shun Chida, Suguru Hayase, Shotaro Fujita, Tomoyuki Monma, Masashi Takawa, Koji Kono, Toru Ohtake, Seiichi Takenoshita
This study aimed to investigate risk factors and prognosis ofcolorectal cancer in patients over 80 years ofage. Surgical risk was evaluated by colorectal POSSUM(CR-POSSUM)and prognosis by Glasgow prognostic score(GPS). The analysis included 56 patients aged over 80 years with colorectal cancer during 2002-2012. Mean operation time, blood loss, and period ofhospitalization were 130 min, 111 mL, and 19.9 days, respectively. Postoperative complications occurred in 26 patients (46.4%; complications group). The 5-year overall survival rate for patients with complication scores above 2 was 51...
November 2016: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/28128541/fenestrated-and-chimney-endovascular-aneurysm-repair-versus-open-surgery-for-complex-abdominal-aortic-aneurysms
#12
Vicente A Sala-Almonacil, José M Zaragozá-García, Mauricio Ramírez-Montoya, Vicente Molina-Nácher, Inmaculada Martínez-Perelló, Francisco J Gómez-Palonés
BACKGROUND: Many patients with complex abdominal aortic aneurysms are unfit for open repair. New endovascular technologies and bailout techniques are being used for managing those complex anatomies. The purpose of this study is to compare the results obtained with advanced endovascular aneurysm repair techniques (fenestrated and chimney endografts) to those obtained with open repair for the treatment of complex abdominal aortic aneurysms not anatomically suitable for standard endovascular exclusion (infrarenal neck <10 mm, juxtarenal, suprarenal and Crawford's type IV thoracoabdominal aneurysms)...
January 27, 2017: Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/28121984/improving-the-design-of-a-conservation-reserve-for-a-critically-endangered-species
#13
Chris Taylor, Natasha Cadenhead, David B Lindenmayer, Brendan A Wintle
Setting aside protected areas is a key strategy for tackling biodiversity loss. Reserve effectiveness depends on the extent to which protected areas capture both known occurrences and areas likely to support the species. We assessed the effectiveness of the existing reserve network for Leadbeater's Possum (Gymnobelideus leadbeateri) and other forest-dependent species, and compared the existing reserve system to a set of plausible reserve expansion options based on area targets implied in a recent Population Viability Analysis (PVA)...
2017: PloS One
https://www.readbyqxmd.com/read/28053107/domain-organization-and-evolution-of-the-highly-divergent-5-coding-region-of-genomes-of-arteriviruses-including-the-novel-possum-nidovirus
#14
Anastasia Gulyaeva, Magdalena Dunowska, Erik Hoogendoorn, Julia Giles, Dmitry Samborskiy, Alexander E Gorbalenya
In five experimentally characterized arterivirus species, the 5'-end genome coding region encodes the most divergent nonstructural proteins (nsp's), nsp1 and nsp2, which include papain-like proteases (PLPs) and other poorly characterized domains. These are involved in regulation of transcription, polyprotein processing, and virus-host interaction. Here we present results of a bioinformatics analysis of this region of 14 arterivirus species, including that of the most distantly related virus, wobbly possum disease virus (WPDV), determined by a modified 5' rapid amplification of cDNA ends (RACE) protocol...
March 15, 2017: Journal of Virology
https://www.readbyqxmd.com/read/28012389/valuing-conservation-benefits-of-disease-control-in-wildlife-a-choice-experiment-approach-to-bovine-tuberculosis-management-in-new-zealand-s-native-forests
#15
Peter Tait, Caroline Saunders, Graham Nugent, Paul Rutherford
We assess the non-monetary environmental benefits that accrue incidentally in New Zealand (NZ) from pest management conducted primarily to control an animal disease, bovine tuberculosis (TB). TB is an infectious disease that is one of the world's most serious animal health problems and, in many parts of the developing world, still a major mortality risk for humans. The incidence of TB in New Zealand (NZ) farmed livestock has been reduced progressively over the last 20 years, largely due to extensive and sustained population control of the main wildlife reservoir of disease, the introduced brushtail possum...
March 15, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28003671/observational-study-to-assess-and-predict-serious-adverse-events-after-major-surgery
#16
Kyoko Shiozaki, Hiroshi Morimatsu, Takashi Matsusaki, Tatsuo Iwasaki
Many patients suffer from postoperative serious adverse events (SAEs). Here we sought to determine the incidence of SAEs, assess the accuracy of currently used scoring systems in predicting postoperative SAEs, and determine whether a combination of scoring systems would better predict postoperative SAEs. We prospectively evaluated patients who underwent major surgery. We calculated 4 scores: American Society of Anesthesiologists physical status (ASA-PS) score, the Charlson Score, the POSSUM (Physiological and Operative Severity Score for the enUmeration of Mortality and morbidity) score, and the Surgical Apgar Score (SAS)...
December 2016: Acta Medica Okayama
https://www.readbyqxmd.com/read/27999663/implementation-of-goal-directed-fluid-therapy-during-hip-revision-arthroplasty-a-matched-cohort-study
#17
Marit Habicher, Felix Balzer, Viktor Mezger, Jennifer Niclas, Michael Müller, Carsten Perka, Michael Krämer, Michael Sander
BACKGROUND: Several randomized controlled trials (RCTs) have demonstrated that intraoperative goal-directed fluid therapy (GDFT) can decrease postsurgical complications in patients undergoing major abdominal surgery. However, very few studies have demonstrated the value of goal-directed therapy (GDT) in patients undergoing orthopaedic surgery and confirmed it is as useful in real-life conditions. Therefore, we initiated a GDFT implementation programme in patients undergoing hip revision arthroplasty in order to assess its effects on postoperative complications (e...
2016: Perioperative Medicine
https://www.readbyqxmd.com/read/27974672/long-term-outcomes-and-propensity-score-matching-analysis-rectal-cancer-resection-for-patients-with-elevated-preoperative-risk
#18
Hao Feng, Tobias S Schiergens, Zhi-Hai Mao, Jingkun Zhao, Xiaohui Shen, Ai-Guo Lu, Wolfgang E Thasler
BACKGROUND: It is still controversial about the treatment strategy for rectal cancer patients with elevated operative risk and elder rectal cancer patients. METHODS: This study presented a retrospective single center experience in rectal cancer proctectomy for high operative risk patients. High operative risk patient was defined as Cr-POSSUM > 5% combined with associated risk factors. 220 in 1477 consecutive patients met the inclusion criteria. RESULTS: 132 patients were selected (66:66) after propensity score matching...
December 9, 2016: Oncotarget
https://www.readbyqxmd.com/read/27927910/validation-of-various-parasite-detection-tests-for-use-in-the-australian-marsupials-quenda-isoodon-obesulus-and-brushtail-possums-trichosurus-vulpecula
#19
Alison E Hillman, Amanda L Ash, Amanda R Kristancic, Aileen D Elliot, Alan J Lymbery, Ian D Robertson, R C Andrew Thompson
We aimed to validate the use of 1) the modified agglutination test and a polymerase chain reaction (PCR) protocol in detecting Toxoplasma gondii infection in quenda ( Isoodon obesulus) and brushtail possums ( Trichosurus vulpecula); 2) immunofluorescence microscopy of feces and a PCR and sequencing protocol in detecting Giardia spp. infection in quenda; and 3) a fecal flotation protocol in detecting gastrointestinal helminth infections of quenda. Quenda and brushtail possum carcasses, and samples from trapped quenda, were tested with 2 parasite detection tests per parasite, and results were modeled using Bayesian latent class analysis to estimate test sensitivity and specificity...
January 2017: Journal of Veterinary Diagnostic Investigation
https://www.readbyqxmd.com/read/27918150/seroprevalence-and-risk-factors-for-leptospira-seropositivity-in-beef-cattle-sheep-and-deer-farmers-in-new-zealand
#20
J M Sanhueza, C Heuer, P R Wilson, J Benschop, J M Collins-Emerson
Leptospirosis is a global zoonosis that in New Zealand affects primarily people occupationally exposed to livestock. The objective of this study was to estimate the seroprevalence of five Leptospira serovars in farmers working on cattle, sheep and deer farms that had the serological status of animals previously assessed and to identify risk factors for farmer seropositivity. A total of 178 farmers from 127 properties participated in the study. Blood samples were tested using the microscopic agglutination test (MAT) for the presence of antibodies to Leptospira...
December 5, 2016: Zoonoses and Public Health
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