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https://www.readbyqxmd.com/read/29688127/the-feasibility-of-a-randomised-controlled-trial-to-compare-the-cost-effectiveness-of-palliative-cardiology-or-usual-care-in-people-with-advanced-heart-failure-two-exploratory-prospective-cohorts
#1
Miriam J Johnson, Paula McSkimming, Alex McConnachie, Claudia Geue, Yvonne Millerick, Andrew Briggs, Karen Hogg
BACKGROUND: The effectiveness of cardiology-led palliative care is unknown; we have insufficient information to conduct a full trial. AIM: To assess the feasibility (recruitment/retention, data quality, variability/sample size estimation, safety) of a clinical trial of palliative cardiology effectiveness. DESIGN: Non-randomised feasibility. SETTING/PARTICIPANTS: Unmatched symptomatic heart failure patients on optimal cardiac treatment from (1) cardiology-led palliative service (caring together group) and (2) heart failure liaison service (usual care group)...
April 1, 2018: Palliative Medicine
https://www.readbyqxmd.com/read/29684370/analytical-validation-and-investigation-on-reference-intervals-of-aldosterone-and-renin-in-chinese-han-population-by-using-fully-automated-chemiluminescence-immunoassays
#2
Lingyan Deng, Zhigang Xiong, Huijun Li, Xiaomei Lei, Liming Cheng
BACKGROUND: The aldosterone/renin ratio (ARR) is recommended to screen for primary aldosteronism (PA) in hypertension. We estimated fully automated chemiluminescence immunoassays (CLIA) for plasma aldosterone concentrations (PAC) and plasma direct renin concentrations (PRC) and investigated their reference intervals in Chinese Han population. METHODS: PAC and PRC were measured on a fully automated analyzer (LIAISON XL, DiaSorin, Italy). Performance characteristics were estimated according to CLSI proved guidelines...
April 20, 2018: Clinical Biochemistry
https://www.readbyqxmd.com/read/29677859/re-evaluation-and-establishment-of-a-ward-based-geriatric-liaison-service-for-older-urological-surgical-patients-proactive-care-of-older-people-undergoing-surgery-pops-urology
#3
https://www.readbyqxmd.com/read/29673969/rgd-cadherins-and-%C3%AE-2%C3%AE-1-integrin-in-cancer-metastasis-a-dangerous-liaison
#4
REVIEW
J Ignacio Casal, Rubén A Bartolomé
We propose a new cadherin family classification comprising epithelial cadherins (cadherin 17 [CDH17], cadherin 16, VE-cadherin, cadherin 6 and cadherin 20) containing RGD motifs within their sequences. Expression of some RGD cadherins is associated with aggressive forms of cancer during the late stages of metastasis, and CDH17 and VE-cadherin have emerged as critical actors in cancer metastasis. After binding to α2β1 integrin, these cadherins promote integrin β1 activation, and thereby cell adhesion, invasion and proliferation, in liver and lung metastasis...
April 16, 2018: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/29671085/-gerontopsychosomatic-consultation-liaison-service-in-inpatient-acute-geriatrics-effects-of-trust-and-support-on-patient-nurse-interaction
#5
REVIEW
Reinhard Lindner
BACKGROUND: Geriatric and psychosomatic medicine follow a biopsychosocial paradigm. Despite this similar "Menschenbild" in general, collaboration between geriatrics and psychosomatics is still rare. OBJECTIVES: This comparative interventional study aims to find possible effects of psychosomatic work in geriatrics on the interaction between patients and nursing staff and contentment of patients with treatment in general. MATERIAL AND METHODS: In the period of one year 238 geriatric patients (return rate 22...
April 18, 2018: Zeitschrift Für Gerontologie und Geriatrie
https://www.readbyqxmd.com/read/29664856/practice-patterns-and-performance-in-u-s-fracture-liaison-programs-an-analysis-of-32-000-patients-from-the-own-the-bone-program
#6
Douglas R Dirschl, Hani Rustom
BACKGROUND: We are not aware of any previous investigation assessing a national cohort of patients enrolled in a fracture liaison service (FLS) program in an open health-care system to ascertain prevalent practice patterns. The objective of this investigation was to determine, in a geographically diverse group of centers in a single FLS program, the percentage of patients for whom anti-osteoporosis treatment was recommended or started as well as to identify associations between patient and fracture variables and the likelihood of treatment being recommended...
April 18, 2018: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/29660206/detection-of-in-vivo-hepatitis-b-virus-surface-antigen-mutations-a-comparison-of-four-routine-screening-assays
#7
M Gencay, A Seffner, S Pabinger, J Gautier, P Gohl, M Weizenegger, D Neofytos, R Batrla, A Woeste, H S Kim, G Westergaard, C Reinsch, E Brill, P T T Thuy, B H Hoang, M Sonderup, C W Spearman, G Brancaccio, M Fasano, G B Gaeta, T Santantonio, W E Kaminski
An important requirement for a state-of-the-art hepatitis B surface antigen (HBsAg) screening assay is reliable detection of mutated HBsAg. Currently, there is a striking shortage of data regarding the detection rates of in vivo HBsAg mutations for these clinically important assays. Therefore, we compared the detection rates of four commercial HBsAg screening assays using a global cohort of 1553 patients from four continents with known HBV genotypes. These samples, which represent the broadest spectrum of known and novel HBsAg major hydrophilic region (MHR) mutations to date, were analyzed for the presence of HBsAg using the Roche Elecsys® HBsAg II Qualitative, Siemens ADVIA Centaur XP HBsAg II, Abbott Architect HBsAg Qualitative II, and DiaSorin Liaison® HBsAg Qualitative assays, respectively...
April 16, 2018: Journal of Viral Hepatitis
https://www.readbyqxmd.com/read/29652954/-time-to-change-the-graduate-postgraduate-liaison-in-chilean-medical-education-reflections-about-a-double-certification-as-physician-and-doctor-in-medical-sciences
#8
Miguel Concha M
In the last 150 years, scientific research has produced extraordinary discoveries in Medicine and there is no doubt that research will continue contributing substantially in the future but there is no the same conviction regarding how to provision such capacities in medical graduates. In Chile, the Faculties of Medicine created several doctorate programs in Medical Sciences (Ph.D.) to strengthen medical research. However, the low number of physicians who apply to these programs is a caveat. These programs provide the advanced third-cycle competencies expected by students aspiring for an excellence research certification and their incorporation into academia...
December 2017: Revista Médica de Chile
https://www.readbyqxmd.com/read/29651059/aesthetic-possibilities-in-removable-prosthodontics-part-3-photometric-tooth-selection-tooth-setting-try-in-fitting-reviewing-and-trouble-shooting
#9
J N Besford, A F Sutton
This final article in a series of three on producing complete dentures which the patient considers attractive, describes selecting the denture teeth, setting the front teeth at the chairside, the try-in visits, processing, fitting and reviewing the dentures. The role of the patient as captain of the ship, the dental nurse as the patient's support and liaison officer, and the clinician as the first technical officer is outlined. The use of immediate replay video technology in allowing a patient to see what the trial denture really looks like is described...
April 13, 2018: British Dental Journal
https://www.readbyqxmd.com/read/29616714/clinical-profile-of-inpatients-referred-to-a-consultation-liaison-psychiatry-service-an-observational-study-assessing-changes-over-a-10-yearperiod
#10
Roberto Sánchez-González, Eva Baillès-Lázaro, Anna Bastidas-Salvadó, Anna Lligoña, Sandra Herranz-Villanueva, Víctor Pérez-Solá, Luis Pintor-Pérez
OBJECTIVE: Previous research has described the characteristics of Consultation-liaison psychiatry (CLP) services over one or more years. The aim of this paper was to examine the patterns of a large sample of patients receiving CLP service over a 10-year-period (2005–2014) and to determine the possible changes over time of the clinical practice. The sample size of our study, the duration of the observation period and the application of standardized operating procedures for acquiring and coding data, will provide more robust evidence than has been reported by most similar studies published in the last years...
March 2018: Actas Españolas de Psiquiatría
https://www.readbyqxmd.com/read/29609858/undetectable-high-density-lipoprotein-cholesterol-in-acute-malaria
#11
Ana Rakovac Tisdall, Vivion Edward Francis Crowley, Martin Andrew Crook
We report the case of a 39-year-old West African man in whom high-density lipoprotein cholesterol (HDL-C) was identified as undetectable at <0.08 mmol/L. Total cholesterol in the same sample was 2.85 mmol/L; triglycerides were only mildly elevated at 2.32 mmol/L. He was admitted with a 2-week history of polydipsia, polyuria, weight loss and hyperpyrexia. Dual malarial infection with Plasmodium ovale and falciparum was identified and attributed to a recent trip to Nigeria without chemoprophylaxis. Also, he was diagnosed with diabetes mellitus with random hyperglycemia of 39 mmol/L but no ketonemia...
March 9, 2018: Journal of Clinical Lipidology
https://www.readbyqxmd.com/read/29606330/characterization-of-disability-following-traumatic-through-knee-and-transfemoral-amputations
#12
David J Tennent, Elizabeth M Polfer, Nicole M Sgromolo, Chad A Krueger, Benjamin K Potter
INTRODUCTION: The purpose of this study is to characterize through knee and transfemoral amputations following severe traumatic injuries. METHODS: A retrospective review of all transfemoral and through knee amputations sustained by United States military service members from 1 October 2001 to 30 July 2011 was conducted. Data from the Department of Defense Trauma Registry, the Armed Forces Health Longitudinal Technology Application, inpatient medical records and the Physical Evaluation Board Liaison Offices were queried in order to obtain characteristics related to injury sustained, demographics, treatment, and disability/mental health outcome data...
March 27, 2018: Injury
https://www.readbyqxmd.com/read/29605113/disuse-osteopenia-following-leg-fracture-in-postmenopausal-women-implications-for-hip-fracture-risk-and-fracture-liaison-services
#13
S J Hopkins, A D Toms, M Brown, A Appleboam, K M Knapp
INTRODUCTION: Disuse osteopenia is a known consequence of reduced weight-bearing and has been demonstrated at the hip following leg injury but has not been specifically studied in postmenopausal women. METHOD: Bilateral DXA (GE Lunar Prodigy) bone mineral density (BMD) measurements were taken at the neck of femur (NOF), total hip region (TH) and lumbar spine in postmenopausal female groups comprising controls (N = 43), new leg fractures (#<3wks) (N = 9), and participants who had sustained a leg fracture more than one year previously (#>1yr) (N = 24)...
May 2018: Radiography
https://www.readbyqxmd.com/read/29600747/the-effectiveness-of-a-hospital-based-school-liaison-program-a-comparative-study-of-parental-perception-of-school-supports-for-children-with-pediatric-cancer-and-neurofibromatosis-type-1
#14
Lisa Northman, Marybeth Morris, Caitlyn Loucas, Sarah Ross, Anna C Muriel, Dongjing Guo, Wendy B London, Peter Manley, Nicole J Ullrich
Childhood survivors of central nervous system (CNS) cancers (defined as cancers whose diagnosis or treatment affect the CNS) are at increased risk for educational related difficulties, as are children affected by neurofibromatosis type 1. This study evaluated the effectiveness of and satisfaction with a model of psychoeducation, consultation, and advocacy provided by a School Liaison Program (SLP) for families and schools of children with CNS-involved cancers compared with a control group of parents of children with a diagnosis of neurofibromatosis type 1 who did not receive school-based services...
March 1, 2018: Journal of Pediatric Oncology Nursing: Official Journal of the Association of Pediatric Oncology Nurses
https://www.readbyqxmd.com/read/29582041/psychostimulant-related-health-service-demand-in-an-inner-city-hospital-2012-2015
#15
Alon Faingold, Kirsten Morley, Bethany White, Emily Walker, Paul Haber
OBJECTIVE: To analyse routinely collected data from a hospital database of drug health consultation-liaison (CL) assessments. We aimed to investigate changes in psychostimulant-related health service demand in an inner-city hospital to inform the development of locally appropriate models of care. METHODS: We used de-identified drug health CL service data from 2012 to 2015. Psychostimulant-related consultations and admissions were compared with opioid-related consultations and admissions over time, by sex and by ward type (medical units, mental health units or emergency department)...
March 15, 2018: Public Health Research & Practice
https://www.readbyqxmd.com/read/29580705/-consultation-liaison-addiction-medicine-tools-and-specificities
#16
P Poloméni, G Cleirec, C Icard, A Ramos, B Rolland
Since the 1970s, the concept of "consultation/liaison (CL) psychiatry" has pertained to specialized mobile teams which meet inpatients hospitalized in non-psychiatric settings to offer them on-the-spot psychiatric assessment, treatment, and, if needed, adequate referral. Since the birth of CL psychiatry, a long set of theoretical books and articles has aimed at integrating CL psychiatry into the wider scope of psychosomatic medicine. In the year 2000, a circular issued by the Health Ministry defined the organization of "CL addiction services" in France...
March 23, 2018: L'Encéphale
https://www.readbyqxmd.com/read/29566192/vitamin-d-status-and-functional-health-outcomes-in-children-aged-2-8-y-a-6-mo-vitamin-d-randomized-controlled-trial
#17
Neil R Brett, Colleen A Parks, Paula Lavery, Sherry Agellon, Catherine A Vanstone, Martin Kaufmann, Glenville Jones, Jonathon L Maguire, Frank Rauch, Hope A Weiler
Background: Most Canadian children do not meet the recommended dietary intake for vitamin D. Objectives: The aims were to test how much vitamin D from food is needed to maintain a healthy serum 25-hydroxyvitamin D3 [25(OH)D3] status from fall to spring in young children and to examine musculoskeletal outcomes. Design: Healthy children aged 2-8 y (n = 51) living in Montreal, Canada, were randomly assigned to 1 of 2 dietary vitamin D groups (control or intervention to reach 400 IU/d by using vitamin D-fortified foods) for 6 mo, starting October 2014...
March 1, 2018: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29564859/-effects-of-an-interdisciplinary-care-program-on-improving-the-return-to-treatment-rate-among-cancer-patients
#18
Mei-Chun Chen, Wan-Yu Chen, Wan-Yu Tsui, Guey-Ling Chang, Ming-Ying Hong
BACKGROUND & PROBLEMS: The return-to-treatment rate is an important indicator of treatment outcome and care effectiveness in cancer patients. The return-to-treatment rates for patients at National Taiwan University Hospital (NTUH) in 2011 and 2012 were 38.5% and 33.3%, respectively. In order to improve the quality of care that is provided to patients, we reviewed NTUH's current clinical case management protocols for handling patients who refused treatment and then identified and resolved the potential problems in these protocols...
April 2018: Hu Li za Zhi the Journal of Nursing
https://www.readbyqxmd.com/read/29564162/evaluation-of-a-health-system-strengthening-initiative-in-the-zambian-prison-system
#19
Stephanie M Topp, Anjali Sharma, Clement N Moonga, Chisele Chileshe, George Magwende, German Henostroza
Introduction: In 2013, the Zambian Correctional Service (ZCS) partnered with the Centre for Infectious Disease Research in Zambia on the Zambian Prisons Health System Strengthening project, seeking to tackle structural, organisational and cultural weaknesses within the prison health system. We present findings from a nested evaluation of the project impact on high, mid-level and facility-level health governance and health service arrangements in the Zambian Correctional Service. Methods: Mixed methods were used, including document review, indepth interviews with ministry (11) and prison facility (6) officials, focus group discussions (12) with male and female inmates in six of the eleven intervention prisons, and participant observation during project workshops and meetings...
2018: BMJ Global Health
https://www.readbyqxmd.com/read/29562010/nurse-liaison-a-strategy-for-counter-referral
#20
Ester do Nascimento Ribas, Elizabeth Bernardino, Liliana Muller Larocca, Paulo Poli Neto, Gisele Knop Aued, Camilla Pinheiro Cristaldi da Silva
OBJECTIVE: to identify the profile of the counter-referred patients by the "nurse liaison" and to describe the experience of the professionals who participated in the project. METHOD: intervention research, with twelve nursing nurses from a hospital and an Emergency Care Unit, and 26 nurses from Primary Health Care. Data were obtained through questionnaires and counter-referral forms. RESULTS: Out of 43 counter-referred individuals, 62...
2018: Revista Brasileira de Enfermagem
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