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Keywords Clinical exercise physiology d...

Clinical exercise physiology diabetes

https://read.qxmd.com/read/38527395/relationship-of-microvascular-complications-and-healthy-lifestyle-with-all-cause-and-cardiovascular-mortality-in-women-compared-with-men-with-type-2-diabetes
#1
JOURNAL ARTICLE
Yu-Jie Liu, Fu-Rong Li, Wen-Wen Han, Yan Liu, Yu Liu, Jia-Min Wang, Meng-Yuan Miao, Jie-Qiong Lyu, Zhong-Xiao Wan, Li-Qiang Qin, Guo-Chong Chen
BACKGROUND: Sex differences exist in the prevalence of microvascular disease (MVD) and healthy-lifestyle adherence. Whether MVD and healthy lifestyles are associated with mortality risk similarly for women and men who have type 2 diabetes mellitus (T2DM) remains unknown. METHODS: The present study included 9992 women and 15,860 men with T2DM from the UK Biobank. MVDs included retinopathy, peripheral neuropathy, and chronic kidney disease. Healthy lifestyle factors consisted of ideal BMI, nonsmoking, healthy diet, regular exercise, and appropriate sleep duration...
March 20, 2024: Clinical Nutrition
https://read.qxmd.com/read/38481537/self-care-practices-and-the-associated-socio-demographic-variables-of-persons-with-type-2-diabetes-mellitus-t2dm-in-southeast-nigeria
#2
JOURNAL ARTICLE
Christiana Nkiru Okafor, Uchenna Prosper Okonkwo, Kenneth Umezulike Ani, Ethel Ogoemeka Onuora, Mathew Nwokike, Jane Turyasingura Byabagambi, Munezero Tamu JohnBosco, Valence Mfitumukiza, Mercy Chinenye Nwankwo, Alex Tumusiime
OBJECTIVE: The study was aimed at assessing the self-care practices and the associated socio-demographic variables of persons with T2DM in South East, Nigeria. METHODOLOGY: A cross-sectional study involving 382 persons with T2DM proportionately selected from 4 tertiary health institutions in South Eastern, Nigeria. Data was collected using the Summary of Diabetes Self-Care Activities (SDSCA) and a researcher-developed questionnaire. The questionnaire was administered to persons with T2DM who attended a diabetic outpatient clinic...
2024: Nutrition and Metabolic Insights
https://read.qxmd.com/read/38445084/a-streamlined-multidisciplinary-metabolic-clinic-in-psychiatric-recovery-service-a-pilot-study
#3
JOURNAL ARTICLE
Kelvin Cy Leung, Bianca Bakr, Cindy Chung, Mayuri Parmar, James Elhindi, Vlasios Brakoulias
BACKGROUND: The metabolic syndrome (MetS) is a collection of risk factors for cardiovascular disease and type-2 diabetes, that includes central obesity, hypertension, hyperglycaemia and dyslipidaemia. An audit indicated inadequate MetS screening in an Australian psychiatric recovery service. OBJECTIVES: We aimed to improve MetS screening, identification and intervention by offering streamlined lifestyle education, clinical reviews and discharge planning. This pilot program prioritized holistic, culturally-sensitive, patient-centric, and trauma-informed approaches to enhance metabolic health outcomes...
2024: Frontiers in Psychiatry
https://read.qxmd.com/read/38397994/hypoglycemia-unawareness-a-review-on-pathophysiology-and-clinical-implications
#4
REVIEW
Laura Hölzen, Bernd Schultes, Sebastian M Meyhöfer, Svenja Meyhöfer
Hypoglycemia is a particular problem in people with diabetes while it can also occur in other clinical circumstances. Hypoglycemia unawareness describes a condition in which autonomic and neuroglycopenic symptoms of hypoglycemia decrease and hence are hardly perceivable. A failure to recognize hypoglycemia in time can lead to unconsciousness, seizure, and even death. The risk factors include intensive glycemic control, prior episodes of severe hypoglycemia, long duration of diabetes, alcohol consumption, exercise, renal failure, and sepsis...
February 8, 2024: Biomedicines
https://read.qxmd.com/read/38367172/mapping-lifestyle-interventions-for-gestational-diabetes-prevention-a-scoping-review
#5
REVIEW
Armando Peña, Alison M Miller, Angela G Campbell, Richard J Holden, Christina M Scifres
PURPOSE OF REVIEW: The purpose of this study was to conduct a scoping review to map intervention, sample, and physiologic measurement characteristics of lifestyle interventions for gestational diabetes mellitus (GDM) prevention. RECENT FINDINGS: A total of 19 studies met selection criteria from 405 articles screened (PubMed, Web of Science). No studies were US-based (47% multi-site), and all were delivered in clinical settings. The most targeted nutrition components were low carbohydrate intake (sugar rich foods/added sugars, low glycemic index), low fat intake (mainly low-fat meat, dairy, and saturated fat), and increased fruits and vegetables...
February 17, 2024: Current Diabetes Reports
https://read.qxmd.com/read/38309688/resolution-of-inflammation-in-chronic-disease-via-restoration-of-the-heat-shock-response-hsr
#6
REVIEW
Helena Trevisan Schroeder, Carlos Henrique De Lemos Muller, Thiago Gomes Heck, Mauricio Krause, Paulo Ivo Homem de Bittencourt
Effective resolution of inflammation via the heat shock response (HSR) is pivotal in averting the transition to chronic inflammatory states. This transition characterizes a spectrum of debilitating conditions, including insulin resistance, obesity, type 2 diabetes, nonalcoholic fatty liver disease, and cardiovascular ailments. This manuscript explores a range of physiological, pharmacological, and nutraceutical interventions aimed at reinstating the HSR in the context of chronic low-grade inflammation, as well as protocols to assess the HSR...
February 2024: Cell Stress & Chaperones
https://read.qxmd.com/read/38263540/postprandial-glucose-management-strategies-in-type-1-diabetes-current-approaches-and-prospects-with-precision-medicine-and-artificial-intelligence
#7
REVIEW
Adnan Jafar, Melissa-Rosina Pasqua
Postprandial glucose control can be challenging for individuals with type 1 diabetes, and this can be attributed to many factors, including suboptimal therapy parameters (carbohydrate ratios, correction factors, basal doses) because of physiological changes, meal macronutrients and engagement in postprandial physical activity. This narrative review aims to examine the current postprandial glucose-management strategies tested in clinical trials, including adjusting therapy settings, bolusing for meal macronutrients, adjusting pre-exercise and postexercise meal boluses for postprandial physical activity, and other therapeutic options, for individuals on open-loop and closed-loop therapies...
January 23, 2024: Diabetes, Obesity & Metabolism
https://read.qxmd.com/read/38238647/feasibility-and-preliminary-efficacy-of-different-intensities-of-functional-training-in-elderly-type-2-diabetes-patients-with-cognitive-impairment-a-pilot-randomised-controlled-trial
#8
JOURNAL ARTICLE
Majid Mardaniyan Ghahfarrokhi, Hossein Shirvani, Mostafa Rahimi, Behzad Bazgir, Alireza Shamsadini, Vahid Sobhani
BACKGROUND: Aging and type-2 diabetes (T2D) are the most important risk factors for cognitive impairment and Alzheimer's disease. Exercise training is an effective, safe, and practical intervention in improving glucose metabolism, physical function, and cognitive disorders. This pilot study investigated the feasibility and preliminary efficacy of high-intensity low-volume (HIFT) vs. low-intensity high-volume (LIFT) functional training in elderly T2D patients with cognitive impairment...
January 18, 2024: BMC Geriatrics
https://read.qxmd.com/read/38201893/sarcopenia-and-diabetes-a-detrimental-liaison-of-advancing-age
#9
REVIEW
Giuseppe Lisco, Olga Eugenia Disoteo, Anna De Tullio, Vincenzo De Geronimo, Vito Angelo Giagulli, Fabio Monzani, Emilio Jirillo, Renato Cozzi, Edoardo Guastamacchia, Giovanni De Pergola, Vincenzo Triggiani
Sarcopenia is an age-related clinical complaint characterized by the progressive deterioration of skeletal muscle mass and strength over time. Type 2 diabetes (T2D) is associated with faster and more relevant skeletal muscle impairment. Both conditions influence each other, leading to negative consequences on glycemic control, cardiovascular risk, general health status, risk of falls, frailty, overall quality of life, and mortality. PubMed/Medline, Scopus, Web of Science, and Google Scholar were searched for research articles, scientific reports, observational studies, clinical trials, narrative and systematic reviews, and meta-analyses to review the evidence on the pathophysiology of di-abetes-induced sarcopenia, its relevance in terms of glucose control and diabetes-related outcomes, and diagnostic and therapeutic challenges...
December 25, 2023: Nutrients
https://read.qxmd.com/read/38140280/weight-management-during-pregnancy-and-the-postpartum-period-in-women-with-gestational-diabetes-mellitus-a-systematic-review-and-summary-of-current-evidence-and-recommendations
#10
REVIEW
Jing Huang, Yi Wu, Hua Li, Hangyu Cui, Qi Zhang, Tianxue Long, Yiyun Zhang, Mingzi Li
BACKGROUND: Weight management during pregnancy and the postpartum period is an important strategy that can be utilized to reduce the risk of short- and long-term complications in women with gestational diabetes mellitus (GDM). We conducted a systematic review to assess and synthesize evidence and recommendations on weight management during pregnancy and the postpartum period in women with GDM to provide evidence-based clinical guidance. METHODS: Nine databases and eighteen websites were searched for clinical decisions, guidelines, recommended practices, evidence summaries, expert consensus, and systematic reviews...
December 6, 2023: Nutrients
https://read.qxmd.com/read/38112970/effects-of-exercise-metformin-and-combination-treatments-on-type-2-diabetic-mellitus-induced-muscle-atrophy-in-db-db-mice-crosstalk-between-autophagy-and-the-proteasome
#11
JOURNAL ARTICLE
Mengqi Xiang, Xinmeng Yuan, Nianyun Zhang, Liumei Zhang, Yuting Liu, Jingjing Liu, Yaran Gao, Ye Xu, Wen Sun, Qiang Tang, Yuan Zhang, Jiao Lu
Both exercise and metformin are common effective clinical treatments of type 2 diabetic mellitus. This study investigated the functional role of exercise, metformin, and combination treatment on type 2 diabetic mellitus-induced muscle atrophy. In this experiment, a total of 10 BKS mice were set as the control group. A total of 40 BKS-db/db mice were randomly divided into the control group (db/db); the exercise intervention group (db/db + Ex), which ran on a treadmill at 7-12 m/min, 30-40 min/day, 5 days/week; the metformin administration group (db/db + Met), which was administered 300 mg/kg of metformin solution by gavage daily; and the exercise combined with metformin administration group (db/db + Ex + Met)...
February 2024: Journal of Physiology and Biochemistry
https://read.qxmd.com/read/38109711/a-very-low-carbohydrate-diet-for-minimising-blood-glucose-excursions-during-ultra-endurance-open-water-swimming-in-type-1-diabetes-a-case-report
#12
JOURNAL ARTICLE
Shania Smee, Rebecca Johnson, Amy Rush, Raymond J Davey
Carbohydrate-restricted diets are used by people with type 1 diabetes (T1D) to help manage their condition. However, the impact of this strategy on blood glucose responses to exercise is unknown. This study describes the nutritional strategies of an athlete with T1D, who follows a very-low-carbohydrate diet to manage her condition during an ultra-endurance open-water swimming event. The athlete completed the 19.7km distance in 6-hours 43-minutes. She experienced minimal disruptions to glycaemia, reduced need for supplemental carbohydrate, and no episodes of symptomatic hypoglycaemia...
December 18, 2023: Applied Physiology Nutrition and Metabolism
https://read.qxmd.com/read/38074329/association-between-cluster-of-differentiation-36-cd36-and-adipose-tissue-lipolysis-during-exercise-training-a-systematic-review
#13
El Mokhtar El Ouali, Laurent Bosquet, Boutaina Elgharbaoui, Fatiha Laziri, Ismail Laher, Anthony C Hackney, Azeddine Ibrahimi, Bouchra Taib, Sanae El Harane, Katja Weiss, Beat Knechtle, Abdelhalem Mesfioui, Hassane Zouhal
Fatty acid translocase (FAT/CD36) is a transmembrane glycoprotein belonging to the scavenger class B receptor family and is encoded by the cluster of differentiation 36 (CD36) gene. This receptor has a high affinity for fatty acids and is involved in lipid metabolism. An abundance of FAT/CD36 during exercise occurs in mitochondria and solitary muscles. As such, we aimed to systematically review the evidence for the relationship FAT/CD36 and adipose tissue lipolysis during exercise training. Five electronic databases were selected for literature searches until June 2022: PubMed, Web of Science, Scopus, science direct, and Google Scholar...
2023: Frontiers in Physiology
https://read.qxmd.com/read/38052023/comparison-of-10-%C3%A3-1-minute-high-intensity-interval-training-hiit-versus-4-%C3%A3-4-minute-hiit-on-glucose-control-and-variability-in-females-with-type-2-diabetes
#14
JOURNAL ARTICLE
Alexis Marcotte-Chénard, Renaud Tremblay, Lara Deslauriers, Pedro Miguel Geraldes, Mathieu Gayda, Demetra Christou, Warner Mampuya, Jonathan P Little, Eléonor Riesco
Two high-intensity interval training (HIIT) regimens are often used in research and clinical settings. Yet there has been no direct comparison to determine if one can improve glucose control and variability to a greater extent in individuals with type 2 diabetes (T2D). Fourteen older females with T2D participated in a semi-randomized control trial where HIIT10 (10×1-minute intervals at 90% heart rate max; HRmax) and HIIT4 (4×4-minute intervals at 90% of HRmax) were compared to a control condition (CON; no exercise)...
December 5, 2023: Applied Physiology Nutrition and Metabolism
https://read.qxmd.com/read/38050866/glucose-metabolism-and-autonomic-function-in-healthy-individuals-and-patients-with-type-2-diabetes-mellitus-at-rest-and-during-exercise
#15
JOURNAL ARTICLE
Takuto Hamaoka, Urs A Leuenberger, Rachel C Drew, Matthew Murray, Cheryl Blaha, Jonathan Carter Luck, Lawrence I Sinoway, Jian Cui
Autonomic dysfunction is a common complication of type 2 diabetes mellitus (T2DM). However, the character of dysfunction varies in different reports. Differences in measurement methodology and complications might have influenced the inconsistent results. We sought to evaluate comprehensively the relationship between abnormal glucose metabolism and autonomic function at rest and the response to exercise in healthy individuals and T2DM patients. We hypothesized that both sympathetic and parasympathetic indices would decrease with the progression of abnormal glucose metabolism in individuals with few complications related to high sympathetic tone...
December 5, 2023: Experimental Physiology
https://read.qxmd.com/read/37942418/a-pilot-retrospective-study-of-a-physician-directed-and-genomics-based-model-for-precision-lifestyle-medicine
#16
JOURNAL ARTICLE
Michael Mallin, Jane Hall, Maria Herlihy, Eduard J Gelman, Michael B Stone
Precision lifestyle medicine is a relatively new field in primary care, based on the hypothesis that genetic predispositions influence an individual's response to specific interventions such as diet, exercise, and prescription medications. Despite the increase in commercially available genomic testing, few studies have investigated effects of a physician-directed program to optimize chronic disease using genomics-based precision medicine. We performed an pilot, observational cohort study to evaluate effects of the Wild Health program, a physician and health coach service offering genomics-based lifestyle and medical interventions, on biomarkers indicative of chronic disease...
2023: Frontiers in Medicine
https://read.qxmd.com/read/37908123/multivariable-automated-insulin-delivery-system-for-handling-planned-and-spontaneous-physical-activities
#17
JOURNAL ARTICLE
Mohammad Reza Askari, Mohammad Ahmadasas, Andrew Shahidehpour, Mudassir Rashid, Laurie Quinn, Minsun Park, Ali Cinar
BACKGROUND: Hybrid closed-loop control of glucose levels in people with type 1 diabetes mellitus (T1D) is limited by the requirements on users to manually announce physical activity (PA) and meals to the artificial pancreas system. Multivariable automated insulin delivery (mvAID) systems that can handle unannounced PAs and meals without any manual announcements by the user can improve glycemic control by modulating insulin dosing in response to the occurrence and intensity of spontaneous physical activities...
November 2023: Journal of Diabetes Science and Technology
https://read.qxmd.com/read/37902107/consumption-of-sucralose-and-acesulfame-potassium-containing-diet-soda-alters-the-relative-abundance-of-microbial-taxa-at-the-species-level-findings-of-two-pilot-studies
#18
JOURNAL ARTICLE
Allison C Sylvetsky, Rebecca A Clement, Nathaniel Stearrett, Najy T Issa, Fiona J Dore, Raja Mazumder, Charles Hadley King, Monica J Hubal, Peter J Walter, Hongyi Cai, Sabyasachi Sen, Kristina I Rother, Keith A Crandall
Sucralose and acesulfame-potassium consumption alters gut microbiota in rodents, with unclear effects in humans. We examined effects of three-times daily sucralose- and acesulfame-potassium-containing diet soda consumption for 1 ( n  = 17) or 8 ( n  = 8) weeks on gut microbiota composition in young adults. After 8 weeks of diet soda consumption, the relative abundance of Proteobacteria, specifically Enterobacteriaceae , increased; and, increased abundance of two Proteobacteria taxa was also observed after 1 week of diet soda consumption compared with sparkling water...
October 30, 2023: Applied Physiology Nutrition and Metabolism
https://read.qxmd.com/read/37892656/therapeutic-exercise-intervention-using-vibration-platforms-for-glycemic-control-in-type-2-diabetes-a-pilot-study
#19
JOURNAL ARTICLE
Juan Fabregat-Fernández, Vicente Rodríguez-Pérez, Rocío Llamas-Ramos, Ana Felicitas López-Rodríguez, Jesús Seco-Calvo, Inés Llamas-Ramos
Diabetes generates a great impact on society, as well as a concern for health professionals due to its high and increasing prevalence; there are several studies that demonstrate the effectiveness of vibration platforms and their benefits at a physiological level. The aim of this study will be to analyze the decrease in glycosylated hemoglobin and glycemia levels after the use of whole-body vibration platforms and the possible inclusion of this therapeutic option within the usual treatments. This is a double-blind, randomized controlled trial with parallel group design in a 1:1 ratio...
October 14, 2023: Journal of Clinical Medicine
https://read.qxmd.com/read/37862820/sodium-glucose-co-transporter-2-inhibitors-and-sarcopenia-a%C3%A2-controversy-that-must-be-solved
#20
REVIEW
Baris Afsar, Rengin Elsurer Afsar
Diabetes mellitus is a risk factor for muscle loss and sarcopenia. Sodium-glucose co-transporter 2 inhibitors (SGLT2i) or "gliflozins" are one of the newest anti-hyperglycemic drugs. They reduce blood glucose levels by inhibiting renal glucose reabsorption in the early proximal convoluted tubule. Various randomized trials showed that SGLT2i have cardio-protective and reno-protective action. SGLT2i also affect body composition. They usually decrease body fat percentage, visceral and subcutaneous adipose tissue...
December 2023: Clinical Nutrition
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