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Exercise therapy obesity

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https://www.readbyqxmd.com/read/28421456/filling-the-void-a-review-of-intragastric-balloons-for-obesity
#1
REVIEW
Patrick Laing, Tuan Pham, Linda Jo Taylor, John Fang
Endoscopic bariatric therapies are predicted to become much more widely used in North America for obese patients who are not candidates for bariatric surgery. Of all the endoscopic bariatric therapies, intragastric balloons (IGBs) have the greatest amount of clinical experience and published data supporting their use. Three IGBs are FDA approved and are now commercially available in the USA (Orbera, ReShape Duo, and Obalon) with others likely soon to follow. They are generally indicated for patients whose BMI ranges from 30 to 40 mg/kg(2) and who have failed to lose weight with diet and exercise...
April 18, 2017: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/28411021/improvement-in-cardiovascular-risk-in-women-after-bariatric-surgery-as-measured-by-carotid-intima-media-thickness-comparison-of-sleeve-gastrectomy-versus-gastric-bypass
#2
Jesús M Gómez-Martin, Enrique Aracil, Julio Galindo, Héctor F Escobar-Morreale, José A Balsa, José I Botella-Carretero
BACKGROUND: Bariatric surgery may diminish cardiovascular risk (CVR) and its associated mortality. However, studies that compare these effects with different techniques are scarce. OBJECTIVE: To evaluate the changes in CVR as estimated by carotid intima-media thickness (IMT) after obesity surgery in women with high CVR as defined by the presence of metabolic syndrome. SETTING: Academic hospital. METHODS: We studied 40 severely obese women, of whom 20 received laparoscopic Roux en Y gastric bypass (RYGB) and 20 received sleeve gastrectomy (SG)...
February 3, 2017: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/28392856/impact-of-physical-activity-in-cardiovascular-and-musculoskeletal-health-can-motion-be-medicine
#3
REVIEW
Gannon L Curtis, Morad Chughtai, Anton Khlopas, Jared M Newman, Rafay Khan, Shervin Shaffiy, Ali Nadhim, Anil Bhave, Michael A Mont
Physical activity is a well-known therapeutic tool for various types of medical conditions, including vasculopathic diseases such as coronary artery disease, stroke, type 2 diabetes, and obesity. Additionally, increased physical activity has been proposed as a therapy to improve musculoskeletal health; however, there are conflicting reports about physical activity potentially leading to degenerative musculoskeletal disease, especially osteoarthritis (OA). Additionally, although physical activity is known to have its benefits, it is unclear as to what amount of physical activity is the most advantageous...
May 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/28377392/effects-of-testosterone-and-evoked-resistance-exercise-after-spinal-cord-injury-terex-sci-study-protocol-for-a-randomised-controlled-trial
#4
Ashraf S Gorgey, Refka E Khalil, Ranjodh Gill, Laura C O'Brien, Timothy Lavis, Teodoro Castillo, David X Cifu, Jeannie Savas, Rehan Khan, Christopher Cardozo, Edward J Lesnefsky, David R Gater, Robert A Adler
INTRODUCTION: Individuals with spinal cord injury (SCI) are at a lifelong risk of obesity and chronic metabolic disorders including insulin resistance and dyslipidemia. Within a few weeks of injury, there is a significant decline in whole body fat-free mass, particularly lower extremity skeletal muscle mass, and subsequent increase in fat mass (FM). This is accompanied by a decrease in anabolic hormones including testosterone. Testosterone replacement therapy (TRT) has been shown to increase skeletal muscle mass and improve metabolic profile...
April 4, 2017: BMJ Open
https://www.readbyqxmd.com/read/28366674/effects-of-high-intensity-interval-training-on-people-living-with-type-2-diabetes-a-narrative-review
#5
REVIEW
Shohn G Wormgoor, Lance C Dalleck, Caryn Zinn, Nigel K Harris
People with type 2 diabetes typically present with comorbidities, such as elevated blood pressure, high cholesterol, high blood glucose, obesity and decreased fitness, all contributive to increased risk for cardiovascular complications. Determination of effective exercise modalities for the management of such complications is important. One such modality is high-intensity interval training (HIIT). To conduct the review, PubMed and EBSCOHost databases were searched through June 1, 2016, for all HIIT intervention studies conducted in people living with type 2 diabetes...
March 30, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28366413/adverse-effects-of-female-obesity-and-interaction-with-race-on-reproductive-potential
#6
REVIEW
Barbara Luke
Across the reproductive spectrum, obesity is associated with greater risks for adverse health outcomes, including higher rates of infertility, subfertility, early pregnancy loss, fetal deaths and stillbirths, congenital anomalies, and pregnancy complications. The excess reproductive morbidity associated with obesity may increase with longer duration, making the current trends among children and young adults particularly critical in terms of their future reproductive potential. Obese women have a lower chance of pregnancy following in vitro fertilization (IVF), require higher dosages of gonadotropins, and have reduced rates of implantation, clinical intrauterine gestation, and live birth rates and increased rates of pregnancy loss, as well as greater risks for prematurity and preeclampsia even when stratified by plurality...
April 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/28359235/halving-your-cake-and-eating-it-too-a-case-based-discussion-and-review-of-metabolic-rehabilitation-for-obese-adults-with-diabetes
#7
R Bishay, N Kormas
BACKGROUND: The global epidemic of obesity will see normal weight adults constituting a mere one-third of the global population by 2025. Although appetite and weight are regulated by a complex integration of neurological, endocrine and gastrointestinal feedback mechanisms, there is a constant interaction between psychological state, physical impairment, presence of comorbid chronic disease and medications. METHODS: We discuss two cases and reveal a practical approach to investigating and managing patients with obesity and diabetes in the 'real world'...
March 29, 2017: Current Diabetes Reviews
https://www.readbyqxmd.com/read/28357467/-ulcers-in-obesity-associated-chronic-venous-insufficiency
#8
L Scholl, M Dörler, M Stücker
BACKGROUND: Chronic venous insufficiency is a frequently occurring disease consisting of a characteristic symptom complex and ulcerations. Normally, varicose veins with reflux or obstruction can be found. However, these symptoms have also been described in obese people and are considered functional chronic venous insufficiency. The aim of this work was to present patients with ulceration in obesity-associated chronic venous insufficiency and to describe typical features of ulceration in obese people...
March 29, 2017: Der Hautarzt; Zeitschrift Für Dermatologie, Venerologie, und Verwandte Gebiete
https://www.readbyqxmd.com/read/28344345/gastric-bypass-surgery-with-exercise-alters-plasma-micrornas-that-predict-improvements-in-cardiometabolic-risk
#9
Y O Nunez Lopez, P M Coen, B H Goodpaster, A A Seyhan
BACKGROUND/OBJECTIVES: Roux-en-Y gastric bypass (RYGB) surgery improves insulin sensitivity (SI) and β-cell function in obese non-diabetic subjects. Exercise also improves SI and may be an effective adjunct therapy to RYGB surgery. However, the mechanisms by which exercise or weight loss improve peripheral SI after RYGB surgery are unclear. We hypothesized that microRNAs (miRNAs) mediate at least some of the regulatory processes driving such mechanisms. Consequently, this work aimed at profiling plasma miRNAs in participants of the Physical Activity Following Surgery Induced Weight Loss study (clinicaltrials...
April 25, 2017: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/28301325/circulating-mirnas-as-biomarkers-of-gait-speed-responses-to-aerobic-exercise-training-in-obese-older-adults
#10
Tan Zhang, Tina E Brinkley, Keqin Liu, Xin Feng, Anthony P Marsh, Stephen Kritchevsky, Xiaobo Zhou, Barbara J Nicklas
Gait speed is a useful predictor of adverse outcomes, including incident mobility disability and mortality in older adults. While aerobic exercise training (AEX) is generally an effective therapy to improve gait speed, individual responses are highly variable. Circulating microRNAs (miRNAs) may contribute to inter-individual changes in gait speed with AEX. We examined whether plasma miRNAs are associated with gait speed changes (dGaitSp) in 33 obese older adults (age: 69.3±3.6 years, BMI: 34.0±3.1 kg/m(2), 85% white, 73% women) who performed treadmill walking, 4 days/week for 5 months...
March 15, 2017: Aging
https://www.readbyqxmd.com/read/28290830/-efficacy-of-home-based-exercise-training-and-adherence-to-therapy-in-patients-after-coronary-artery-bypass-grafting
#11
S A Pomeshkina, E B Loktionova, N V Arkhipova, O L Barbarash
AIM: to assess efficacy of home-based exercise training (HBET) at outpatient stage of cardiac rehabilitation and its impact on adherence to treatment in patients after coronary artery bypass grafting (CABG). MATERIAL AND METHODS: In 1 month after CABG 112 male patients (after completion of rehabilitation program in the sanatorium) were distributed to 3 groups with comparable demographic, clinical, and functional parameters: group 1 - patients fulfilling supervised cycling training program (SCTP), group 2 - patients subjected to home-based exercise training (HBET) with defined walking sessions (WS), and the control group of usual care without exercise training...
January 2017: Kardiologiia
https://www.readbyqxmd.com/read/28270444/alpha-linolenic-acid-supplementation-and-exercise-training-reveal-independent-and-additive-responses-on-hepatic-lipid-accumulation-in-obese-rats
#12
Paula M Miotto, Meaghan Horbatuk, Ross Proudfoot, Sarthak Matravadia, Marica Bakovic, Adrian Chabowski, Graham P Holloway
Alpha-linolenic acid (ALA) supplementation or exercise training can independently prevent hepatic lipid accumulation and reduced insulin signaling, however, this may occur through different mechanisms-of-action. In the current study, obese Zucker rats displayed decreased phospholipid (PL) content in association with hepatic lipid abundance, and therefore, we examined whether ALA and exercise training would prevent these abnormalities differently to reveal additive effects on the liver. To achieve this aim, obese Zucker rats were fed control diet alone or supplemented with ALA, and were sedentary or exercise trained for 4 weeks (C-Sed, ALA-Sed, C-Ex, ALA-Ex)...
March 7, 2017: American Journal of Physiology. Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28269449/implantable-gastric-electric-stimulator-with-automatic-daily-activity-compliance-reporting
#13
Eri Takami, Javier J Sanchez, Rose Province, Antonio J Torres
In order for any obesity therapy to be successful real behavior change by the individual is required. We present an implantable obesity therapy that combines gastric electrical stimulation for satiety with onboard sensors that provide self-monitoring for the patient and compliance reporting to the clinician. An algorithm for processing data from the onboard three axis accelerometer for use in physical activity monitoring was developed and validated. Four obese patients participated in a study where self-reported sleep and exercise was compared with the events detected by the implanted system, and two commercially available, wearable activity monitors...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28239482/aggressive-clinical-approach-to-obesity-improves-metabolic-and-clinical-outcomes-and-can-prevent-bariatric-surgery-a-single-center-experience
#14
Flavio A Cadegiani, Gustavo C Diniz, Gabriella Alves
BACKGROUND: The number of bariatric procedures has exponentially increased in the past decade, as a result of the lack of successful clinical weight-loss interventions. The main reasons for the failure of clinical obesity management are: (1) anti-obesity medications are administered as monotherapies (or pre-combined drugs); (2) lack of combination between pharmacotherapy and non-pharmacological modalities; (3) short duration of pharmacotherapy for obesity; (4) lack of weight-loss maintenance strategies; (5) misunderstanding of the complex pathophysiology of obesity; and (6) underprescription of anti-obesity medications...
2017: BMC Obesity
https://www.readbyqxmd.com/read/28227695/implantable-gastric-electric-stimulator-with-automatic-daily-activity-compliance-reporting
#15
Eri Takami, Javier J Sanchez, Rose Province, Antonio J Torres, Eri Takami, Javier J Sanchez, Rose Province, Antonio J Torres, Eri Takami, Javier J Sanchez, Antonio J Torres, Rose Province
In order for any obesity therapy to be successful real behavior change by the individual is required. We present an implantable obesity therapy that combines gastric electrical stimulation for satiety with onboard sensors that provide self-monitoring for the patient and compliance reporting to the clinician. An algorithm for processing data from the onboard three axis accelerometer for use in physical activity monitoring was developed and validated. Four obese patients participated in a study where self-reported sleep and exercise was compared with the events detected by the implanted system, and two commercially available, wearable activity monitors...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28209386/dietary-therapy-in-heart-failure-with-preserved-ejection-fraction-and-or-left-ventricular-diastolic-dysfunction-in-patients-with-metabolic-syndrome
#16
REVIEW
Helene von Bibra, Alexander Ströhle, Martin St John Sutton, Nicolai Worm
BACKGROUND: Heart failure is an ongoing epidemic of left ventricular (LV) dilatation and/or dysfunction due to the increasing prevalence of predisposing risk factors such as age, physical inactivity, (abdominal) obesity, and type-2-diabetes. Approximately half of these patients have diastolic heart failure (HFpEF). The prognosis of HFpEF is comparable to that of systolic heart failure, but without any known effective treatment. DIASTOLIC DYSFUNCTION: A biomathematically corrected diagnostic approach is presented that quantifies diastolic dysfunction via the predominant age dependency of LV diastolic function and unmasks (metabolic) risk factors, that are independent of age and, therefore, potential targets for therapy...
May 1, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28163315/effects-of-topical-capsaicin-combined-with-moderate-exercise-on-insulin-resistance-body-weight-and-oxidative-stress-in-hypoestrogenic-obese-rats
#17
J M L Medina-Contreras, J Colado-Velázquez, N L Gómez-Viquez, P Mailloux-Salinas, I Perez-Torres, A Aranda-Fraustro, K Carvajal, G Bravo
BACKGROUND: Hypoestrogenic women are one of the most vulnerable groups for the development of obesity and its complications. Capsaicin and exercise have demonstrated to reduce body weight and to improve insulin sensitivity in different animal models, but it is unknown whether their combination could be useful in hypoestrogenic obese females. METHODS: We investigated whether topical capsaicin, exercise or their combination had better therapeutic effects in an obesity-hypoestrogenism model...
February 6, 2017: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/28163011/aerobic-endurance-training-improves-nonalcoholic-fatty-liver-disease-nafld-features-via-mir-33-dependent-autophagy-induction-in-high-fat-diet-fed-mice
#18
Parvin Ghareghani, Mehrnoosh Shanaki, Saeideh Ahmadi, Ali Reza Khoshdel, Neda Rezvan, Reza Meshkani, Maryam Delfan, Sattar Gorgani-Firuzjaee
Due to changes in life style, obesity and obesity related complication such as insulin resistance, type 2 diabetes and non-alcoholic fatty liver disease caused worldwide health problems. Regular exercise has been frequently prescribed to combat metabolic complication of obesity but its molecular mechanism has not been fully illustrated. We investigated molecular mechanism of lipid lowering effect of exercise training in high fat diet fed mice by focusing on miR-33 expression and autophagy pathway. 24 mice were assigned to normal chow (NC) (n=8), high-fat diet (HFD) (n=16) group and subjected to NC and HFD for 13-weeks...
February 2, 2017: Obesity Research & Clinical Practice
https://www.readbyqxmd.com/read/28155616/crosstalk-between-oxidative-and-nitrosative-stress-and-arterial-stiffness
#19
Ioana Mozos, Constantin Tudor Luca
Arterial stiffness, the expression of reduced arterial elasticity, is an effective predictor of cardiovascular disorders. Oxidative stress is an imbalance between exposure to toxic reactive oxygen species (ROS) and antioxidant systems. The increase in reactive nitrogen species (RNS) is termed nitrosative stress. We review the main mechanisms and products linking arterial stiffness with oxidative and nitrosative stress in several disorders, focusing on recent experimental and clinical data, and the mechanisms explaining benefits of antioxidant therapy...
February 1, 2017: Current Vascular Pharmacology
https://www.readbyqxmd.com/read/28150485/obesity-and-cardiovascular-diseases
#20
Sergey Kachur, Carl J Lavie, Alban de Schutter, Richard V Milani, Hector O Ventura
Obesity is increasingly more common in postindustrial societies, and the burden of childhood obesity is increasing. The major effects of obesity on cardiovascular (CV) health are mediated through the risk of metabolic syndrome (insulin-resistance, dyslipidemia, and hypertension), such that an absence of these risk factors in obese individuals may not be associated with increased mortality risk. In individuals already diagnosed with chronic CV disease (CVD), the overweight and class I obese have significant associations with improved survival...
June 2017: Minerva Medica
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