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https://www.readbyqxmd.com/read/29912223/-ten-questions-about-pericardial-effusion
#1
Massimo Imazio, George Lazaros, Antonio Brucato
Although a new or worsening pericardial effusion is a diagnostic criterion for pericarditis, in clinical practice the presence of pericardial effusion does not necessarily imply the evidence of pericarditis. Up to 40-50% of cases of pericarditis do not show the presence of pericardial effusion (dry pericarditis). The clinician should first evaluate any related symptoms and signs (symptomatic vs asymptomatic), its size and hemodynamic impact, then rule out pericarditis and the presence of an underlying disease (e...
June 2018: Giornale Italiano di Cardiologia
https://www.readbyqxmd.com/read/29911052/is-iodine-excess-associated-with-increased-incidence-of-hypothyroidism
#2
Subramanian Kannan, Sudha Rathna Prabhu, Shriraam Mahadevan
No abstract text is available yet for this article.
March 2018: Indian Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29911045/congenital-hypothyroidism-screening-in-term-neonates-using-umbilical-cord-blood-tsh-values
#3
Ravi Bhatia, Dinesh Rajwaniya
Congenital hypothyroidism remains one of the most common preventable causes of mental retardation among children. Screening for congenital hypothyroidism remains one of the most cost-effective tools to prevent mental retardation in the population. Umbilical cord blood thyroid-stimulating hormone (TSH) levels remain an attractive and a practical step for screening for congenital hypothyroidism. The aims of this study were as follows: (1) to find normative values of cord blood TSH for the study group and (2) to use cord blood TSH levels as a marker for screening of congenital hypothyroidism...
March 2018: Indian Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29911035/subclinical-hypothyroidism-and-cardiac-risk-lessons-from-a-south-indian-population-study
#4
Sashi Niranjan Nair, Harish Kumar, Manoj Raveendran, V Usha Menon
Introduction: The benefits of treating subclinical hypothyroidism are currently under debate, prevention of adverse cardiac events purporting to be one of the main benefits. The effect of subclinical hypothyroidism on the cardiovascular health of the Indian sub-population is largely unknown. This study was designed to examine these effects and to help guide treatment of this disorder. Methods: A cross-sectional adult population survey was carried out in urban coastal area of central Kerala...
March 2018: Indian Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29910183/rhabdomyolysis-in-a-patient-complicated-with-hypopituitarism-and-multiple-organ-dysfunction-syndrome-and-the-literature-review
#5
Chuan Zhou, Shichao Lai, Yong Xie, Shu Zhang, Yiping Lu
INTRODUCTION: Muscular symptoms, including stiffness, myalgia, cramps, and fatigue, are present in the majority of the patients with hypopituitarism, adrenal insufficiency and hypothyroidism, but rhabdomyolysis, the rapid breakdown of skeletal muscle, is a rare manifestation. In most patients who develop rhabdomyolysis, precipitating factors, such as strenuous exercise or use of lipid-lowering drugs, can be identified. CASE REPORT: We report the case of a 23-year-old male with primary hypopituitarism who developed acute renal impairment (AKI) with rhabdomyolysis after strenuous physical activity (push-ups)...
June 7, 2018: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29910160/influence-of-thyroid-peroxidase-antibodies-on-tsh-levels-of-pregnant-women-and-maternal-fetal-complications
#6
Paula Fernández Martínez, Rocío Aguado García, David Emilio Barajas Galindo, Ana Hernández Moreno, Mirian Alejo Ramos, Sara García Arias, María D Ballesteros Pomar, Isidoro Manuel Cano Rodríguez
INTRODUCTION: During pregnancy, thyroid peroxidase (TPO) antibodies may increase the risk of developing subclinical hypothyroidism (SCH). Both conditions appear to be associated to maternal-fetal complications. The objectives of this study were to analyze if a relationship exists between TSH and TPO levels during pregnancy and the potential effects on gestational and perinatal complications, and to assess whether detectable, but not positive, TPO levels have an impact on development of gestational SCH...
June 14, 2018: Endocrinología, Diabetes y Nutrición
https://www.readbyqxmd.com/read/29910159/nivolumab-induced-thyroid-dysfunction-in-patients-with-lung-cancer
#7
Ana M Ramos-Levi, Jacobo Rogado, Jose Miguel Sanchez-Torres, Ramón Colomer, Mónica Marazuela
BACKGROUND: Nivolumab is an anti-cancer monoclonal antibody that inhibits PD1 and modulates T-cell response. It has been shown to significantly improve survival in several types of cancer, but clinical trials have also reported an increased risk of developing immune-related adverse events (IRAEs). Endocrine IRAEs may be particularly relevant. OBJECTIVE: To comprehensively evaluate the clinical presentation of endocrine IRAEs in patients with lung cancer treated with nivolumab...
June 14, 2018: Endocrinología, Diabetes y Nutrición
https://www.readbyqxmd.com/read/29908479/incident-thyroid-disease-in-female-spouses-of-private-pesticide-applicators
#8
Srishti Shrestha, Christine G Parks, Whitney S Goldner, Freya Kamel, David M Umbach, Mary H Ward, Catherine C Lerro, Stella Koutros, Jonathan N Hofmann, Laura E Beane Freeman, Dale P Sandler
BACKGROUND: Little is known about modifiable risk factors for thyroid disease. Several pesticides have been implicated in thyroid disruption, but clinical implications are not clear. OBJECTIVE: We assessed associations between pesticide use and other farm exposures and incident hypothyroidism and hyperthyroidism in female spouses of farmers in the Agricultural Health Study (AHS). METHODS: We used Cox proportional hazards models to estimate hazard ratios (HR) and 95% confidence intervals for risk of thyroid disease in 24,092 spouses who completed at least one follow-up questionnaire...
June 13, 2018: Environment International
https://www.readbyqxmd.com/read/29906034/schmidt%C3%A2-s-syndrome-a-difficult-diagnosis-in-the-latin-american-context
#9
Claudia Barreda-Velit, Rodrigo Salcedo-Pereda, Jesús Ticona
Background: Schmidt’s syndrome, also known as poliglandular autoimmune syndrome type 2, is a rare disease that has a prevalence between 1.5-4.5 cases per 100 000 inhabitants. The diagnosis consists in the concomitant presentation of Addison disease, autoimmune thyroid disease and other autoimmune endocrinological conditions. The aim of this paper is to describe a case of Schmidt’s syndrome in the peruvian context and to analyze the difficulties in the diagnosis. Clinical case: We present the case of a 43-year-old woman that presents to the emergency room with headache, nausea, vomits and a “syncope episode”...
March 2018: Revista Médica del Instituto Mexicano del Seguro Social
https://www.readbyqxmd.com/read/29904593/case-report-pulmonary-and-liver-sarcoidosis-suspected-of-metastasis
#10
Behnam Jafari, Gholamabas Sabz, Elahe Masnavi, Roghaye Panahi, Saeid Jokar, Amrollah Roozbehi, Sajad Hasanzadeh
Introduction : Sarcoidosis is a granulomatous disease with unknown cause that can vary from an asymptomatic condition. Almost half of the patients with sarcoidosis have no symptoms. In this article, we describe a sarcoidosis patient with lung and liver engagement; it may be confused with metastasis. Case report : A 39-year-old man, known as hypothyroidism who had come to the emergency ward with dyspnea and coughing after exposure to detergents in a closed environment A 39-year-old man, known as hypothyroidism who had come to the emergency ward with dyspnea and coughing after exposure to detergents in a closed environment...
2018: F1000Research
https://www.readbyqxmd.com/read/29903225/-status-of-lactating-women-s-iodine-nutrition-and-thyroid-function-in-different-iodine-nutrition-level-of-children-in-gansu-province
#11
Yugui Dou, Yanling Wang, Wei Sun, Yongqin Cao, Xiaonan Zhu, Jing Zheng
OBJECTIVE: To assess the iodine nutrition and thyroid function of lactatingwomen in different iodine nutrition level of children in Gansu Province, and provide a scientific basis for iodine supplementation. METHODS: Liangzhou district( the median urinary iodine was greater than or equal to 300 g/L), Linze county( the median urinary iodine was from 200 to 299 g/L) and Huating county( the median urinary iodine was from100 to 199 g/L) were selected according to 8-10 years old children urinary iodine in2009...
January 2018: Wei Sheng Yan Jiu, Journal of Hygiene Research
https://www.readbyqxmd.com/read/29902156/hypertriglyceridemia-thalassemia-syndrome
#12
Mili Jain, Wahid Ali, Brijendra Bahadur Singh, Nishant Verma, Ashutosh Kumar
BACKGROUND: Hypertriglyceridemia thalassemia syndrome is a rare entity with an unknown pathogenetic link. CASE PRESENTATION: We report a case of an 8-month-old female with thalassemia major and increased triglyceride (TG) levels. The clinical features were as in classical thalassemia except for a white discoloration of the plasma. After exclusion of familial triglyceridemia and secondary causes (hypothyroidism, nephrotic syndrome, drugs etc.), a diagnosis of hypertriglyceridemia thalassemia syndrome was made...
June 14, 2018: Journal of Pediatric Endocrinology & Metabolism: JPEM
https://www.readbyqxmd.com/read/29900922/a-systematic-analysis-on-possibility-of-water-fluoridation-causing-hypothyroidism
#13
REVIEW
Nallan C S K Chaitanya, P Karunakar, Neeharika Satya Jyothi Allam, M Hima Priya, B Alekhya, Shaguftha Nauseen
Background: Community water fluoridation is widely used worldwide and its role in preventive dental health care is well established. However, there is sufficient evidence of the ill effects of excessive fluoride content in water, causing skeletal and dental fluorosis. Alongside, there was also extraskeletal and dental manifestations of excessive fluorides reported. They include the effect on thyroid function, but the literature regarding this is sparse. Aim: The present systematic review aims to analyze the data from controlled studies about the effect of fluoride on thyroid function...
May 2018: Indian Journal of Dental Research: Official Publication of Indian Society for Dental Research
https://www.readbyqxmd.com/read/29897016/the-impact-of-hypothyroidism-and-heart-failure-on-hospitalization-risk
#14
Kevin Ro, Alexander D Yuen, Lin Du, Clarissa C Ro, Christian D Seger, Michael W Yeh, Angela M Leung, Connie M Rhee
BACKGROUND: Prior studies suggest that the relationship between hypothyroidism and mortality is dependent on underlying cardiovascular risk. Little is known about the association of hypothyroidism with hospitalization risk, and how these associations are modified by cardiovascular status. METHODS: We examined the association of thyroid status, defined by serum thyrotropin (TSH), with hospitalization risk among patients who received care from a large university-based tertiary care center over 1990-2015...
June 13, 2018: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/29896988/influence-of-hypothyroidism-on-testicular-mitochondrial-oxidative-stress-by-activating-the-p38-mitogen-activated-protein-kinase-and-c-jun-nh-2-terminal-kinase-signaling-pathways-in-rats
#15
X-R Chang, Y-L Yao, D Wang, H-T Ma, P-H Gou, C-Y Li, J-L Wang
Thyroid hormone deficiency can impair testicular function. However, knowledge of the effects of mitogen-activated protein kinase (MAPK) pathways on testicular mitochondrial oxidative damage induced by hypothyroidism is still rudimentary. This study aims to explore the possible mechanisms of testicular mitochondrial oxidative damage in hypothyroidism rats. Wistar male rats were randomly divided into control (C), low- (L), and high-hypothyroidism (H) groups (1 ml/100 g body weights (BWs)/day 0, 0.001% and 0.1% propylthiouracil, respectively) by intragastric gavage for 60 days...
January 1, 2018: Human & Experimental Toxicology
https://www.readbyqxmd.com/read/29896255/therapeutic-effects-of-acupuncture-with-mok-a-polyherbal-medicine-on-ptu-induced-hypothyroidism-in-rats
#16
Ji Hye Hwang, Hyo Won Jung, Seok Yong Kang, An Na Kang, Jun Nan Ma, Xiang Long Meng, Min Sub Hwang, Yong-Ki Park
Acupuncture with MOK, a polyherbal medicine (MOK pharmacopuncture), has been used for the treatment of thyroid syndromes including hypothyroidism and hyperthyroidism in traditional Korean medicine. The present study investigated the effect of MOK pharmacopuncture on hypothyroidism and the mechanism underlying its antioxidation and immune regulation effects. Hypothyroidism was induced in Sprague-Dawley rats by subcutaneous injection of Propylthiouracil (PTU; 10 mg/kg) once daily for 4 weeks. MOK was administered by acupuncture on the acupoints around the thyroid gland of PTU-induced hypothyroidism rats once daily for 2 weeks following hypothyroidism induction...
July 2018: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29895366/effect-of-maternal-and-neonatal-factors-on-neonatal-thyroid-stimulating-hormone-results-from-a-population-based-prospective-cohort-study-in-china
#17
Yixin Zhang, Cong Du, Wei Wang, Wen Chen, Ping Shao, Chongdan Wang, Junhong Leng, Jun Shen, Long Tan, Wanqi Zhang
OBJECTIVE: Neonatal TSH screening is effective in detecting congenital hypothyroidism and estimating iodine status in a given population, but various factors influence TSH levels. The aim of this study was to evaluate the effect of maternal and neonatal factors on neonatal TSH levels. DESIGN AND SETTING: Data were obtained from an ongoing prospective cohort study. A total of 988 pregnant women and their newborn infants participated in the study from April 2015 to May 2017 at Tianjin Maternal and Child Health Center and Tanggu Maternity Hospital in Tianjin, China...
September 2018: Journal of Trace Elements in Medicine and Biology
https://www.readbyqxmd.com/read/29893484/clinical-utility-of-endocrine-markers-predicting-myocardial-siderosis-in-transfusion-dependent-thalassemia-major
#18
Lubaina Ehsan, Mariam Rashid, Najveen Alvi, Khadija Awais, Omair Nadeem, Aleezay Asghar, Fatimah Sajjad, Malika Fatima, Asim Qidwai, Shabneez Hussain, Erum Hasan, Nick Brown, Sadaf Altaf, Babar Hasan, Salman Kirmani
BACKGROUND: Endocrinopathy due to iron overload is the most common morbidity whereas myocardial siderosis causing toxic cardiomyopathy is the leading cause of mortality among patients with transfusion dependent thalassemia major (TDTM). If detected early, this can be treated with aggressive chelation. T2* cardiac magnetic resonance imaging (CMR) guided chelation protocols are now the gold standard but have limited availability in low and middle-income countries. We hypothesized that markers of endocrine dysfunction would correlate with T2* CMR and can be used to predict the severity of myocardial siderosis and guide chelation therapy...
June 12, 2018: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/29893010/prevalence-of-thyroid-dysfunction-in-a-large-southern-european-population-analysis-of-modulatory-factors-the-apna-study
#19
Silvia Santos Palacios, María Llavero Valero, Antonio Brugos-Larumbe, Juan José Díez, Francisco Guillén-Grima, Juan C Galofré
CONTEXT: To study the prevalence of thyroid dysfunction in a very large unselected population. OBJECTIVE: To determine the prevalence of abnormal thyroid function and evaluate potential modulatory factors. DESIGN AND SETTING: The Estudio de Atención Primaria de Navarra, The APNA Study, is a cross-sectional study conducted in northern Spain. It involved 303,883 people, of 20 years of age and older, who live in the Navarra region. Participants are covered by the public healthcare system and medical records are digitalized...
June 12, 2018: Clinical Endocrinology
https://www.readbyqxmd.com/read/29892820/protocols-for-studying-how-thyroid-hormone-receptors-trigger-adaptive-thermogenesis-in-mice
#20
Karine Gauthier
The ability of thyroid hormone T3 to stimulate energy expenditure and regulate different aspects of whole body metabolism has been recognized for over a 100 years. Indeed in 1895 Adolf Magnus Levy was already describing the influence of the thyroid on setting the basal metabolic rate. Now it has been well characterized that the level of circulating T3 is correlated with energy expenditure both in humans and in rodent models (Mullur et al., Physiol Rev 94:355-382, 2014; Silva, Thyroid 5:481-492, 1995). Hypothyroidism and hyperthyroidism are respectively associated with low and high energy expenditure leading to high and low body mass index...
2018: Methods in Molecular Biology
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