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https://www.readbyqxmd.com/read/29777228/effects-of-clomiphene-citrate-on-male-obesity-associated-hypogonadism-a-randomized-double-blind-placebo-controlled-study
#1
Andressa Heimbecher Soares, Nidia Celeste Horie, Lucas Augusto Piccinin Chiang, Bruno Caramelli, Mariana Gomes Matheus, Alexandre Holthausen Campos, Luciana Cavalheiro Marti, Fernanda Agostini Rocha, Marcio C Mancini, Elaine Maria Frade Costa, Cintia Cercato
BACKGROUND: Obesity causes secondary hypogonadism (HG) in men. Standard testosterone (T) replacement therapy improves metabolic parameters but leads to infertility. OBJECTIVE: To evaluate clomiphene citrate (CC) treatment of adult men with male obesity-associated secondary hypogonadism (MOSH). DESIGN: Single-center, randomized, double-blind, placebo-controlled trial. PARTICIPANTS: Seventy-eight men aged 36.5 ± 7...
May 17, 2018: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/29773856/hyperbaric-oxygen-can-induce-angiogenesis-and-recover-erectile-function
#2
Amir Hadanny, Erez Lang, Laurian Copel, Oshra Meir, Yair Bechor, Gregory Fishlev, Jacob Bergan, Amnon Zisman, Shai Efrati
Erectile dysfunction (ED) is caused by microvascular or macrovascular insufficiency in the majority of patients. Recent studies have shown that hyperbaric oxygen therapy (HBOT) can induce angiogenesis in different body organs. The effect of HBOT on the non-surgery-related ED has not been investigated yet. The aim of the current study was to evaluate the effects of HBOT on sexual function and penile vascular bed in non-surgical ED patients. A prospective analysis of patients suffering from chronic ED treated with 40 daily HBOT sessions...
May 18, 2018: International Journal of Impotence Research
https://www.readbyqxmd.com/read/29765930/effect-of-fennel-on-the-health-status-of-menopausal-women-a-systematic-and-meta-analysis
#3
Talat Khadivzadeh, Mona Najaf Najafi, Leila Kargarfard, Masumeh Ghazanfarpour, Fatemeh Rajab Dizavandi, Imaneh Khorsand
Objectives: The aim of the present study is the systematic and critical investigation of the effectiveness of fennel on the climacteric symptoms among menopausal females. Methods: A search of the trials studying the effect of fennel on menopausal females was conducted in 2017 using the MEDLINE and Scopus databases and the Cochrane Library with the following keywords: fennel, Foeniculum vulgare , and menopause. Results: Fennel combined with officinalis is more effective in the attenuating of sleep disorders compared to Citalopram...
April 2018: Journal of Menopausal Medicine
https://www.readbyqxmd.com/read/29757572/comparison-of-the-kelly-s-plication-and-tot-simultaneously-with-vaginal-hysterectomy-on-the-incontinence-and-sexual-functions
#4
Neslihan Bayramoglu Tepe, Omer Bayrak, Huseyin Caglayan Ozcan, Mete Gurol Ugur, Ilker Seckiner
PURPOSE: To compare the effect of vaginal hysterectomy-anterior/posterior colporrhaphy with Kelly's plication(VH-KP), versus vaginal hysterectomy-anterior/posterior colporrhaphy-transobturator tape(VH-TOT) surgeries on incontinence, quality of life, and sexual functions in patients with pelvic organ prolapse(POP), and concurrent obvious stress urinary incontinence(SUI). MATERIALS AND METHODS: Between 2013 and 2017, fifty patients treated with VH-KP(n = 25), and VH-TOT(n = 25) due to POP and SUI, were evaluated prospective consecutively...
May 5, 2018: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/29757454/non-pharmacological-interventions-for-treating-chronic-prostatitis-chronic-pelvic-pain-syndrome
#5
REVIEW
Juan Va Franco, Tarek Turk, Jae Hung Jung, Yu-Tian Xiao, Stanislav Iakhno, Virginia Garrote, Valeria Vietto
BACKGROUND: Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a common disorder in which the two main clinical features are pelvic pain and lower urinary tract symptoms. There are currently many approaches for its management, using both pharmacological and non-pharmacological interventions. The National Institute of Health - Chronic Prostatitis Symptom Index (NIH-CPSI) score is a validated measure commonly used to measure CP/CPPS symptoms. OBJECTIVES: To assess the effects of non-pharmacological therapies for chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS)...
May 12, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29757096/when-solving-dyspareunia-is-not-enough-to-restore-sexual-function-in-women-with-deep-infiltrating-endometriosis-treated-with-dienogest
#6
João Paulo Leonardo-Pinto, Cristina Laguna Benetti-Pinto, Daniela Angerame Yela
OBJECTIVE: The aim of the study was evaluated dyspareunia and sexual function (SF) in women with deep endometriosis treated with Dienogest for 12 months. METHODS: Prospective cohort study set in University of Campinas, Brazil, including thirty women with sonographic diagnosis of deep endometriosis and sexual dysfunction treated with 2░mg/daily Dienogest for 12 months. SF parameters were assessed by Female Sexual Function Index (FSFI) before and after the treatment and dyspareunia was quantified through Visual Analogic Scale(VAS) during the follow ups performed every 3 months...
May 14, 2018: Journal of Sex & Marital Therapy
https://www.readbyqxmd.com/read/29755571/plasma-oxytocin-level-and-sexual-dysfunction-in-depressed-women-treated-by-either-fluoxetine-or-citalopram-a-pilot-clinical-trial
#7
Mohammad Abbasinazari, Mona Heidari-Kord, Azadeh Mazaheri-Meybodi, Azadeh Eshraghi, Nima Bayati
Sexual dysfunction is a common cause of selective serotonin reuptake inhibitor (SSRI) withdrawal. Various studies indicate that decreased oxytocin is involved as a mechanism of delayed ejaculation induced by SSRIs. The aim of the present pilot study was to evaluate and compare sexual dysfunction and oxytocin levels in women being treated with either fluoxetine or citalopram. Thirty-nine women with the diagnosis of major depressive disorder were enrolled in the study. A baseline blood sample was collected and each participant was given either fluoxetine 20 mg/d or citalopram 20 mg/d...
2018: Iranian Journal of Pharmaceutical Research: IJPR
https://www.readbyqxmd.com/read/29753801/a-comparative-study-between-2-different-grafts-used-as-patches-after-plaque-incision-and-inflatable-penile-prosthesis-implantation-for-end-stage-peyronie-s-disease
#8
Marco Falcone, Mirko Preto, Carlo Ceruti, Massimiliano Timpano, Giulio Garaffa, Omidreza Sedigh, Mattia Sibona, Marco Oderda, Paolo Gontero, Luigi Rolle
BACKGROUND: Although many grafts have been used for plaque incision with grafting (PIG) and penile prosthesis (PP) implantation, there is no evidence that favors 1 specific graft over another. AIM: To compare fibrin-coated collagen fleece (TachoSil; Baxter International, Deerfield, IL, USA) with porcine small intestinal submucosa (SIS; Cook Biotech, West Lafayette, IN, USA) as grafts. METHODS: From January 2007 to January 2015, 60 non-randomized consecutive patients affected by end-stage Peyronie disease underwent PIG and PP implantation (AMS 700CX; Boston Scientific, Marlborough, MA, USA)...
May 9, 2018: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/29753799/predictors-of-erectile-function-normalization-in-men-with-erectile-dysfunction-treated-with-placebo
#9
John P Mulhall, Martin Carlsson, Vera Stecher, Li-Jung Tseng
BACKGROUND: Clinical study and practice data have shown sildenafil improves sexual function in men with erectile dysfunction (ED). However, some men treated with placebo in double-blind, placebo-controlled sildenafil studies also report improved erectile function as measured by International Index of Erectile Function (IIEF)-Erectile Function Domain (EFD) scores. AIM: This analysis estimated the relationship between post-baseline IIEF-EFD scores and demographic variables, including co-morbidities, in men with ED receiving placebo in flexible-dose sildenafil studies...
May 9, 2018: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/29753213/onabotulinumtoxina-detrusor-injection-improves-female-sexual-function-in-women-with-overactive-bladder-wet-syndrome
#10
Matteo Balzarro, Emanuele Rubilotta, Andrea Braga, Silvia Bassi, Tania Processali, Walter Artibani, Maurizio Serati
OBJECTIVES: The correlation between changes in sexual function and improvements in LUTD in patients treated with OnabotulinumtoxinA (onaBoNT-A) detrusor injection is unclear and limited only to women with neurogenic OAB. The aim of this study was to evaluate the impact of OnabotulinumtoxinA (onaBoNT-A) injection on sexual function in women undergoing this treatment for idiopathic wet overactive bladder (OAB). STUDY DESIGN: This is a pilot three-center observational study including women affected by idiopathic wet overactive bladder refractory to standard conservative treatments and underwent onaBoNT-A injection...
May 5, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29751956/relation-of-postexercise-reduction-of-arterial-blood-pressure-and-erectile-dysfunction-in-patients-with-coronary-heart-disease
#11
Dariusz Kałka, Jana Gebala, Lesław Rusiecki, Ryszard Smoliński, Jakub Dulanowski, Małgorzata Rusiecka, Anna Biełous-Wilk, Witold Pilecki, Krzysztof Womperski, Romuald Zdrojowy
Penile erection is a hemodynamic process consisting of 2 synchronized components in which the first (active) requires proper vascular endothelium functioning, whereas the second one (passive) is based on a veno-occlusive mechanism. Antihypertensive treatment reduces the passive component, often leading to the development of erectile dysfunction (ED), but lifestyle modifications can improve the sexual functioning. The study aimed to evaluate the association between blood pressure (BP) reduction caused by cardiovascular training and the intensity of ED in men with coronary heart disease...
April 18, 2018: American Journal of Cardiology
https://www.readbyqxmd.com/read/29751592/does-type-1-diabetes-modify-sexuality-and-mood-of-women-and-men
#12
Ewelina Bak, Czeslaw Marcisz, Sylwia Krzeminska, Dorota Dobrzyn-Matusiak, Agnieszka Foltyn, Agnieszka Drosdzol-Cop
BACKGROUND: Sexual disorders occurring in women and men with type 1 diabetes have not been sufficiently investigated and described until now. This study attempts to evaluate sexuality in women and men. METHODS: Altogether, the study comprised 115 patients with type 1 diabetes and 105 healthy people constituting the control group. All the studied persons underwent survey studies determining sexuality using the Female Sexual Function Index (FSFI-19) in women and the International Index of Erectile Function (IIEF-15) in men, and the occurrence of depression using the Beck Depression Inventory...
May 11, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29746287/sexual-functioning-in-hyperprolactinemic-patients-treated-with-cabergoline-or-bromocriptine
#13
Robert Krysiak, Bogusław Okopień
BACKGROUND: Elevated prolactin levels were found to be associated with impaired sexuality. STUDY QUESTION: The aim of the study was to compare the impact of bromocriptine and cabergoline on sexual functioning in both genders. STUDY DESIGN: The study enrolled 39 young women and 18 young men receiving bromocriptine treatment. In 19 women and 8 men, because of poor tolerance, bromocriptine was replaced with cabergoline, whereas the remaining ones continued bromocriptine treatment...
May 1, 2018: American Journal of Therapeutics
https://www.readbyqxmd.com/read/29732206/patient-experience-after-transperineal-template-prostate-biopsy-compared-to-prior-transrectal-ultrasound-guided-prostate-biopsy
#14
Nikita R Bhatt, Kieran Breen, Usman M Haroon, Muhammad Akram, Hugh D Flood, Subhasis K Giri
Introduction: Transperineal template prostate biopsy (TTPB) is reported to have higher cancer detection and lower complication rate compared to transrectal ultrasound guided prostate biopsy (TRUSPB).However, there is no report of the same patient's experience with both types of biopsy.To compare the patient reported experience in the same cohort of patients who underwent both TRUSPB and TTPB, using validated questionnaires. Material and methods: We retrospectively utilised the Patient Reported Outcome Methods (PROM) tool validated for TRUSPB and the International Index of Erectile Function (IIEF-5) questionnaire to collect longitudinal data at follow-up in the same cohort of patients who underwent both TTPB and TRUSPB between January 2015 and February 2016...
2018: Central European Journal of Urology
https://www.readbyqxmd.com/read/29730645/sexual-function-is-an-indicator-of-central-arterial-stiffness-and-arterial-stiffness-gradient-in-japanese-adult-men
#15
Hiroshi Kumagai, Toru Yoshikawa, Kanae Myoenzono, Keisei Kosaki, Nobuhiko Akazawa, Zempo-Miyaki Asako, Takehiko Tsujimoto, Tetsuhiro Kidokoro, Kiyoji Tanaka, Seiji Maeda
BACKGROUND: As arterial stiffness increases in the absence of subjective symptoms, a personal indicator that reflects increased risk of cardiovascular disease is necessary. Penile erection is regulated by vascular function, and atherosclerosis affects the penile artery earlier than it affects the coronary and carotid arteries. Therefore, we hypothesized that deterioration of erectile function could be a marker of increased risk for cardiovascular disease. To test our hypothesis, we assessed erectile function and arterial stiffness in a cross-sectional study...
May 5, 2018: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29730199/sexual-function-in-a-nationwide-cohort-of-2260-testicular-cancer-survivors-after-17-years-follow-up
#16
Mikkel Bandak, Jakob Lauritsen, Christoffer Johansen, Michael Kreiberg, Julie Wang Skøtt, Mads Agerbaek, Niels V Holm, Gedske Daugaard
PURPOSE: Evidence on the long-term impact of testicular cancer (TC) treatment on sexual function is not clear. The aim was to estimate the effect of TC treatment on the risk of sexual dysfunction in long-term testicular cancer survivors. MATERIALS AND METHODS: We conducted a cross-sectional study of 2260 long-term TC survivors (median follow-up 17 years (IQR 12-24 years)) treated with orchiectomy alone (surveillance) (n=1098), bleomycin, etoposide, cisplatin (BEP) (BEP alone or BEP with post chemotherapy retroperitoneal surgery (n=788), abdominal radiotherapy (RT) (n=300), and more than one line of treatment (MTOL) (n=74)...
May 3, 2018: Journal of Urology
https://www.readbyqxmd.com/read/29727543/-efficacy-and-safety-of-traditional-chinese-medicine-combined-with-sildenafil-in-the-treatment-of-ed-in-chinese-men%C3%AF-a-real-world-study
#17
Jun Guo, De-Gui Chang, Lei Chen, Bin Ou-Yang, Rui Zhang, Qiang Geng, Chao Yu, Fu Wang, Qing-He Gao, Guo-Jin Yu, Xiu-Ju Zhang
Objective: To make a real-world study on the efficacy and safety of traditional Chinese medicine (TCM) combined with sildenafil in the treatment of erectile dysfunction (ED) that failed to respond to TCM medication. METHODS: This study included 1 038 ED patients with the International Index of Erectile Function-5 (IIEF-5) scores ≤21 and improvement <30% after 4 weeks of TCM medication, differentially diagnosed with kidney-yang or kidney-yin deficiency syndrome...
October 2017: Zhonghua Nan Ke Xue, National Journal of Andrology
https://www.readbyqxmd.com/read/29727536/-obstructive-sleep-apnea-affects-the-sexual-function-of-the-male-patient
#18
Kang-Lun Jiang, Wei Qian, Zhi-Qiang Lin, Lin Zhao, Shu Shao, Asad Iqbal Muhammad
Objective: To explore the factors influencing the sexual function of the male patients with obstructive sleep apnea (OSA). METHODS: Using Arizona Sexual Experience Scale (ASEX) and Epworth Sleepiness Scale (ESS), we conducted a questionnaire investigation among 81 male patients with OSA aged 40.5 ± 8.6 years and 35 healthy volunteers aged 38.8 ± 10 years. According to the sex drive (SD) score in ASEX, we divided the OSA patients into an SD reduction group (SD score = 4, n = 32) and a non-SD reduction group (SD score <4, n = 49), compared the clinical data and polysomnographic (PSG) indexes, and analyzed the factors influencing SD by evaluating the association of the PSG indexes with the SD score...
October 2017: Zhonghua Nan Ke Xue, National Journal of Andrology
https://www.readbyqxmd.com/read/29726916/treatment-to-external-labia-and-vaginal-canal-with-co2-laser-for-symptoms-of-vulvovaginal-atrophy-in-postmenopausal-women
#19
Julene B Samuels, Martin A Garcia
Background: Increasingly, women have sought alternatives to traditional options (lubricants, estrogen products, and hormone replacement therapy) for unwelcome vaginal changes of menopause. Objectives: This study evaluated whether a series of three monthly fractional CO2 laser treatments significantly improves and maintains vaginal health indices of elasticity, fluid volume, pH level, epithelial integrity, and moisture. Self-reported symptoms of vaginal atrophy were also measured...
April 13, 2018: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/29725284/sexual-dysfunction-prevalence-in-a-group-of-pre-and-postmenopausal-mexican-women
#20
Sebastián Carranza-Lira, Flor de Durazno Casillas Núñez
Introduction: To determine the prevalence of sexual dysfunction in pre and postmenopausal women. Material and methods: A cross-sectional, descriptive, comparative study was done in climacteric women from 40 to 59 years of age. Female sexual function was evaluated with the female sexual function index (FSFI) on the day of consultation. The comparison between pre and postmenopausal women and between those with or without sexual dysfunction was done with Mann Whitney U test, χ2 , and Spearman's correlation analysis was done...
March 2018: Przeglad Menopauzalny, Menopause Review
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