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https://www.readbyqxmd.com/read/28529704/towards-a-systems-approach-for-chronic-diseases-based-on-health-state-modeling
#1
Michael Rebhan
Rising pressure from chronic diseases means that we need to learn how to deal with challenges at a different level, including the use of systems approaches that better connect across fragments, such as disciplines, stakeholders, institutions, and technologies. By learning from progress in leading areas of health innovation (including oncology and AIDS), as well as complementary indications (Alzheimer's disease), I try to extract the most enabling innovation paradigms, and discuss their extension to additional areas of application within a systems approach...
2017: F1000Research
https://www.readbyqxmd.com/read/28526620/evidence-for-cortical-structural-plasticity-in-humans-after-a-day-of-waking-and-sleep-deprivation
#2
Torbjørn Elvsåshagen, Nathalia Zak, Linn B Norbom, Per Ø Pedersen, Sophia H Quraishi, Atle Bjørnerud, Dag Alnæs, Nhat Trung Doan, Ulrik F Malt, Inge R Groote, Lars T Westlye
Sleep is an evolutionarily conserved process required for human health and functioning. Insufficient sleep causes impairments across cognitive domains, and sleep deprivation can have rapid antidepressive effects in mood disorders. However, the neurobiological effects of waking and sleep are not well understood. Recently, animal studies indicated that waking and sleep are associated with substantial cortical structural plasticity. Here, we hypothesized that structural plasticity can be observed after a day of waking and sleep deprivation in the human cerebral cortex...
May 16, 2017: NeuroImage
https://www.readbyqxmd.com/read/28525924/institutional-review-board-training-when-patients-and-community-members-are-engaged-as-researchers
#3
John M Westfall, Linda Zittleman, Maret Felzien, Marc Ringel, Alison Lakin, Don Nease
Background.: Patient engagement efforts often rely on a participatory research approach, which means engaging patients and community members in all aspects of research. As research team members, they require familiarity with the principles of human subject protection, privacy, and institutional review boards (IRB). However, the time required for individual IRB training may be a barrier to engaging community members in participatory research. As more community members participated in research, the State Networks of Colorado Practices and Partners (SNOCAP) was faced with finding a balance between including community members as part of the research team and the significant time commitment and institutional requirements for human subjects research oversight...
June 1, 2017: Family Practice
https://www.readbyqxmd.com/read/28525320/sexual-and-reproductive-health-priorities-of-adolescent-girls-in-lagos-nigeria-findings-from-free-listing-interviews
#4
Juliet Iwelunmor, Sarah Blackstone, Ucheoma Nwaozuru, Donaldson Conserve, Patricia Iwelunmor, John E Ehiri
Background Adolescent girls in Nigeria experience a disproportionately high burden of sexual and reproductive health disparities that affect their well-being. Yet, little is known about adolescent girls' own unique perspectives of the sexual and reproductive health challenges they face, and possible solutions to these challenges. Aims To explore top sexual and reproductive health concerns of female adolescents in Nigeria and their perceptions regarding potential solutions to these issues. Methods Eighty adolescent girls attending two public secondary schools in Lagos, Nigeria completed individual free-listing interviews...
May 17, 2017: International Journal of Adolescent Medicine and Health
https://www.readbyqxmd.com/read/28521751/an-integrated-intervention-to-reduce-intimate-partner-violence-and-psychological-distress-with-refugees-in-low-resource-settings-study-protocol-for-the-nguvu-cluster-randomized-trial
#5
Wietse A Tol, M Claire Greene, Samuel Likindikoki, Lusia Misinzo, Peter Ventevogel, Ann G Bonz, Judith K Bass, Jessie K K Mbwambo
BACKGROUND: Intimate partner violence (IPV) is a critical public health and human rights concern globally, including for refugee women in low-resource settings. Little is known about effective interventions for this population. IPV and psychological distress have a bi-directional relationship, indicating the potential benefit of a structured psychological component as part of efforts to reduce IPV for women currently in violent relationships. METHODS: This protocol describes a cluster randomized controlled trial aimed at evaluating an 8-session integrated psychological and advocacy intervention (Nguvu) with female adult survivors of past-year IPV displaying moderate to severe psychological distress...
May 18, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28513865/diagnosis-of-tuberculosis-in-hiv-co-infected-individuals-current-status-challenges-and-opportunities-for-the-future
#6
REVIEW
P Méndez-Samperio
Tuberculosis (TB) remains one of the most important causes of death amongst people co-infected with human immunodeficiency virus (HIV). The diagnosis of TB remains challenging in HIV co-infected individuals, due to a high frequency of smear-negative disease and high rates of extrapulmonary TB. Accurate, ease of use, and rapid diagnosis of active TB is critical to the World Health Organization (WHO) End TB Strategy by 2050. Traditional laboratory techniques do not provide rapid and accurate results to effectively manage HIV co-infected patients...
May 17, 2017: Scandinavian Journal of Immunology
https://www.readbyqxmd.com/read/28512076/considering-the-public-in-public-health-popular-resistance-to-the-smallpox-eradication-programme-in-india
#7
Luke Juran, Jennifer Trivedi, Korine N Kolivras
Public health initiatives, including large-scale vaccination and disease eradication programmes, regularly pit the rights of the individual against broader benefits to society. At times, the public resists such initiatives, with the World Health Organisation's Smallpox Eradication Programme (SEP) in India being a case in point. Here, we critically investigate resistance to smallpox vaccines in India and argue that while the SEP successfully eradicated a global killer; individuals were stripped of human rights through coercion, forcible vaccination and quarantine...
April 2017: Indian Journal of Medical Ethics
https://www.readbyqxmd.com/read/28504041/book-review-disordered-personalities-and-crime-an-analysis-of-the-history-of-moral-insanity-mental-illness-human-rights-and-the-law-mental-health-and-the-criminal-justice-system-a-social-work-perspective-handbook-of-secure-care-and-secure-lives-the-meaning
#8
https://www.readbyqxmd.com/read/28499386/gender-equality-and-human-rights-approaches-to-female-genital-mutilation-a-review-of-international-human-rights-norms-and-standards
#9
REVIEW
Rajat Khosla, Joya Banerjee, Doris Chou, Lale Say, Susana T Fried
Two hundred million girls and women in the world are estimated to have undergone female genital mutilation (FGM), and another 15 million girls are at risk of experiencing it by 2020 in high prevalence countries (UNICEF, 2016. Female genital mutilation/cutting: a global concern. 2016). Despite decades of concerted efforts to eradicate or abandon the practice, and the increased need for clear guidance on the treatment and care of women who have undergone FGM, present efforts have not yet been able to effectively curb the number of women and girls subjected to this practice (UNICEF...
May 12, 2017: Reproductive Health
https://www.readbyqxmd.com/read/28497581/what-could-cognitive-capital-mean-for-china-s-children
#10
Douglas J Noble, Kathryn Martin, Lisa Qin, Pia Britto, Margo O'sullivan, Jillian Popkins, Ron Pouwels, Robert W Scherpbier, Rana Flowers
Cognitive capital is an emerging paradigm that captures the criticality of investing in children whilst neural proliferation and development of brain architecture are at their peak. Distinct from financial capital, cognitive capital represents investment in future human potential from interventions in nutrition, health, education, child protection, and social welfare systems that optimize brain development. The return on investment is significant given the plasticity of the developing brain in response to positive stimuli...
May 12, 2017: PsyCh Journal
https://www.readbyqxmd.com/read/28496954/sexual-risk-behaviors-constructed-in-iranian-women-s-life-with-substance-use-disorders-a-new-implication-of-human-ecological-theory
#11
Mansoureh Jamshidimanesh, Seyed Abbas Mousavi, Effat Merghati-Khoei, Mohammad Hassan Emamian, Afsaneh Keramat
BACKGROUND: Drug abuse is one of the important variables influencing protective sexual behavior. The objective of this study was to explore how risky sexual behaviors develop in drug abusing women using human ecological theory. METHODS: In this study, we used a descriptive exploratory approach. The participants were 32 drug abusing women from two of the selected drop-in centers (DICs) in south Tehran, Iran, where we could have access to a vast number of female drug users...
July 2016: Addiction & Health
https://www.readbyqxmd.com/read/28495549/a-blind-spot-on-the-global-mental-health-map-a-scoping-review-of-25-years-development-of-mental-health-care-for-people-with-severe-mental-illnesses-in-central-and-eastern-europe
#12
REVIEW
Petr Winkler, Dzmitry Krupchanka, Tessa Roberts, Lucie Kondratova, Vendula Machů, Cyril Höschl, Norman Sartorius, Robert Van Voren, Oleg Aizberg, Istvan Bitter, Arlinda Cerga-Pashoja, Azra Deljkovic, Naim Fanaj, Arunas Germanavicius, Hristo Hinkov, Aram Hovsepyan, Fuad N Ismayilov, Sladana Strkalj Ivezic, Marek Jarema, Vesna Jordanova, Selma Kukić, Nino Makhashvili, Brigita Novak Šarotar, Oksana Plevachuk, Daria Smirnova, Bogdan Ioan Voinescu, Jelena Vrublevska, Graham Thornicroft
Just over 25 years have passed since the major sociopolitical changes in central and eastern Europe; our aim was to map and analyse the development of mental health-care practice for people with severe mental illnesses in this region since then. A scoping review was complemented by an expert survey in 24 countries. Mental health-care practice in the region differs greatly across as well as within individual countries. National policies often exist but reforms remain mostly in the realm of aspiration. Services are predominantly based in psychiatric hospitals...
May 8, 2017: Lancet Psychiatry
https://www.readbyqxmd.com/read/28493602/avenacosides-metabolism-and-potential-use-as-exposure-biomarkers-of-oat-intake
#13
Pei Wang, Junli Yang, Aaron Yerke, Shengmin Sang
SCOPE: Exposure biomarkers used for objective estimation of whole-grain (WG) intake are essential for epidemiologic studies of WG consumption, however, up to now, no exposure biomarkers were developed for WG oat intake. This study investigates the potential of oat unique components, Avenacoside-B (AVE-B) and -A (AVE-A), as exposure biomarkers of oat intake. METHODS AND RESULTS: An in vivo study performed in mice and an in vitro batch fecalfermentation study were used to investigate the potential metabolic routes of AVE-B and -A...
May 11, 2017: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/28492117/biobanks-in-south-africa-a-global-perspective-on-privacy-and-confidentiality
#14
Riaan Rheeder
The Universal Declaration of Bioethics and Human Rights (UDBHR) of the United Nations Educational, Scientific and Cultural Organization (UNESCO) was adopted unanimously in 2005 by the world community as a universal guideline, according to which members of the global community were accountable to each other. Research results from UNESCO show that the UDBHR has had little or no impact in South Africa (SA). The primary objective of this article is to promote awareness of the UDBHR in SA and Africa by focusing on Article 9 of the Declaration, which accepts the right to privacy and confidentiality...
April 25, 2017: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
https://www.readbyqxmd.com/read/28489278/growth-of-indoor-fungi-on-gypsum
#15
Frank J J Segers, Karel A van Laarhoven, Han A B Wösten, Jan Dijksterhuis
AIMS: To have a better understanding of fungal growth on gypsum building materials to prevent indoor fungal growth. METHODS AND RESULTS: Gypsum is acquired by mining or as a by-product of flue-gas desulfurization or treatment of phosphate ore for the production of fertilizer. Natural gypsum, flue-gas gypsum, and phosphogypsum therefore have different mineral compositions. Here, growth of fungi on these types of gypsum was assessed. Conidia of the indoor fungi Aspergillus niger, Cladosporium halotolerans, and Penicillium rubens were inoculated and observed using microscopic techniques including low temperature scanning electron microscopy (Cryo-SEM)...
May 10, 2017: Journal of Applied Microbiology
https://www.readbyqxmd.com/read/28488805/breastfeeding-considerations-for-mothers-of-infants-with-neonatal-abstinence-syndrome
#16
Amy P Holmes, Holly N Schmidlin, Eliana N Kurzum
Breastfeeding offers many benefits to both mother and baby. Breastfeeding is generally recommended for mothers of infants with neonatal abstinence syndrome (NAS) unless some associated risk outweighs the benefits. Evidence indicates that infants with NAS who receive human milk require less pharmacologic treatment and have shorter hospital lengths of stay. Perhaps the greatest barrier to breastfeeding for women with opioid dependence is the inaccurate and inconsistent information they receive from different sources, including health care professionals...
May 10, 2017: Pharmacotherapy
https://www.readbyqxmd.com/read/28487305/a-rohingya-refugee-s-journey-in-australia-and-the-barriers-to-accessing-healthcare
#17
Manasi Jiwrajka, Ahmad Mahmoud, Maneeta Uppal
Australia's processing of some asylum seekers on offshore detention centres has recently been brought to light by human rights organisation. While the internal politics of resettling refugees may be complex, Australia remains in the top five countries for resettlement per capita. However, these refugees remain a vulnerable patient population after immigrating. Refugee women, an understudied group, in particular experience higher adverse health outcomes.In this case report, we follow the medical journey of KB, a 38-year-old Rohingya refugee diagnosed with type 2 diabetes mellitus-the crux of all her health issues...
May 9, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28480969/epidemiological-and-genetic-analysis-concerning-the-non-enterovirus-71-and-non-coxsackievirus-a16-causative-agents-related-to-hand-foot-and-mouth-disease-in-anyang-city-henan-province-china-from-2011-to-2015
#18
Yang Li, Honghong Bao, Xiangping Zhang, Mingqiang Zhai, Xiaobing Bao, Demin Wang, Shuanhu Zhang
Enterovirus 71 (EV-A71) and coxsackievirus A16 (CV-A16) are major pathogens of hand, foot and mouth disease (HFMD) and have been associated with consecutive outbreaks of HFMD in China over the past years. Although several other human enteroviruses (HEVs) have also acted as causative agents of HFMD, published information on their roles in the prevalence of HFMD is limited. This study was conducted to reveal the characteristics of the pathogenic spectrum and molecular epidemiology of the non-EV-71 and non-CV-A16 HEVs in Anyang City, which is located in north-central China and has a population of 5 million...
May 8, 2017: Journal of Medical Virology
https://www.readbyqxmd.com/read/28477409/alma-ata-to-berlin-diabetes-prevention-and-treatment-to-achieve-healthy-living
#19
S Kalra, T Lauritzen, T Sharmanov, Z Akanov, F Al Awadi, A K Das, C Espinosa López, G Medea, P Oh, Y Samoilova, M Shestakova, P Netto, X Cos, M Farghaly, X Du
The 1978 Declaration of Alma-Ata [1], issued at the International Conference on Primary Health Care*, held at Alma-Ata, Kazakhstan (former Soviet Union), is a landmark in public health. By stating that health is a fundamental human right, the declaration promoted interest and action in the field of public health, specifically primary health care. While it highlighted maternal child health and infectious disease control, it also clearly addressed chronic illness care, the availability of appropriate pharmaceuticals, and the need for preventive, curative and rehabilitative services...
May 6, 2017: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/28476445/characteristic-patterns-of-normal-meridian-acupoint-temperature
#20
Han-Ning Wei, Li-Ping Jiang, Bin Xiong, Si Zhou, Lan Yu, Yan-Mei Huang, Dao-Guang Liu, Wei Ling, Xin-Nan Song, Xiao-Xi Zhang, Hai-Lu Zhao
BACKGROUND: Body temperature is an important indicator of health and illness. However, a single temperature measurement is not always reliable. Such measurements can be made using meridians, which are energy channels with acupoints being the nodes. To date, there is no published reference of meridian acupoint temperatures applicable to human health, and there is no clear digitalized indicator that could be utilized to evaluate human health by way of meridian acupoints up to now. METHODS: Our study recruited 100 healthy medical college students for the measurement of acupoint temperature...
May 2, 2017: Journal of the Chinese Medical Association: JCMA
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