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https://www.readbyqxmd.com/read/29348073/rate-of-switch-from-bipolar-depression-into-mania-after-morning-light-therapy-a-historical-review
#1
REVIEW
Francesco Benedetti
Light therapy (LT) is efficacious for bipolar depression with effect sizes equivalent to those in antidepressant pharmacotherapy trials. Patients with bipolar disorder (BD) show a 15-40% rate of manic switches during antidepressant drug treatment. The rate of manic switches during LT has never been estimated. We searched all the literature studies reporting effects of antidepressant LT in BD. 41 studies described 799 patients with BD treated with antidepressant LT, from among which 7 (0.9%) switched into mania and 11 (1...
January 9, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29343947/patient-preferences-for-important-attributes-of-bipolar-depression-treatments-a-discrete-choice-experiment
#2
Daisy Ng-Mak, Jiat-Ling Poon, Laurie Roberts, Leah Kleinman, Dennis A Revicki, Krithika Rajagopalan
Purpose: The purpose of this study was to assess patient preferences regarding pharmacological treatment attributes for bipolar depression using a discrete choice experiment (DCE). Methods: Adult members of an Internet survey panel with a self-reported diagnosis of bipolar depression were invited via e-mail to participate in a web-based DCE survey. Participants were asked to choose between hypothetical medication alternatives defined by attributes and levels that were varied systematically...
2018: Patient Preference and Adherence
https://www.readbyqxmd.com/read/29342846/mental-health-and-drivers-of-need-in-emergent-and-non-emergent-emergency-department-ed-use-do-living-location-and-non-emergent-care-sources-matter
#3
Moira C McManus, Robert J Cramer, Maureen Boshier, Muge Akpinar-Elci, Bonnie Van Lunen
Emergency department (ED) utilization has increased due to factors such as admissions for mental health conditions, including suicide and self-harm. We investigate direct and moderating influences on non-emergent ED utilization through the Behavioral Model of Health Services Use. Through logistic regression, we examined correlates of ED use via 2014 New York State Department of Health Statewide Planning and Research Cooperative System outpatient data. Consistent with the primary hypothesis, mental health admissions were associated with emergent use across models, with only a slight decrease in effect size in rural living locations...
January 13, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29339689/atherogenic-index-of-plasma-as-a-cardiovascular-risk-marker-in-manic-depressive-and-euthymic-stages-of-bipolar-disorder
#4
Tevfik Kalelioğlu, Pelin Ünalan, Burcu Kök, Şule Sözen, Özge Yüksel, Mustafa Akkuş, Refik Cihnioğlu, Nesrin Karamustafalıoğlu
OBJECTIVE: Individuals with bipolar disorder (BD) frequently suffer from cardiovascular disease (CVD), and it is a leading cause of mortality. Clinicians use routine laboratory tests, including a lipid profile, to predict cardiovascular risk. In addition, a particular lipid ratio, the atherogenic index of plasma (AIP), is a sensitive, new parameter that can be used to assess highrisk groups. To our knowledge, this is the first study evaluating cardiovascular risk via AIP in different stages of BD...
January 2018: Türk Kardiyoloji Derneği Arşivi: Türk Kardiyoloji Derneğinin Yayın Organıdır
https://www.readbyqxmd.com/read/29329041/thiol-disulphide-homeostasis-in-bipolar-disorder
#5
Gamze Erzin, Vahap Ozan Kotan, Canan Topçuoğlu, Güven Özkaya, Özcan Erel, Rabia Nazik Yüksel, Emre Ürer, Makbule Çiğdem Aydemir, Erol Göka
Bipolar disorder (BD) patients have increased oxidative stress, which can disturb thiol/disulphide homeostasis, causing disulphide formation. The aim of the study is to investigate dynamic thiol/disulphide (SH/SS) homeostasis in BD patients, which is a novel evaluation method of oxidative status. Ninety-four BD patients (50 in the manic episode and 44 in remission) and 44 healthy controls were included in the study. Blood serum native thiol (SH) and total thiol (ToSH) concentrations were measured in a paired test...
January 2, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29327316/-diagnosis-differential-diagnosis-and-therapy-of-substance-use-disorders-in-general-hospital-general-section
#6
REVIEW
Anton Schmick, Josef Jenewein, Sönke Böttger
Substance use disorders are becoming an increasingly significant problem in general hospitals and hence play a key role in consultation- and liaison psychiatry. Diverse psychotropic effects of various substances mimic psychiatric disorders. An alcohol intoxication can present depressive or manic symptoms, a cannabis delirium can present as a psychosis while stimulants use can suggest the diagnosis of an anxiety disorder. Obtaining dual diagnoses by identifying substance-induced and non-substance-induced psychopathologies is clinically challenging...
January 11, 2018: Neuropsychiatrie: Klinik, Diagnostik, Therapie und Rehabilitation
https://www.readbyqxmd.com/read/29322397/overlapping-and-distinct-neural-metabolic-patterns-related-to-impulsivity-and-hypomania-in-parkinson-s-disease
#7
Frank Schwartz, Masoud Tahmasian, Franziska Maier, Luisa Rochhausen, Kim L Schnorrenberg, Fateme Samea, Joseph Seemiller, Mojtaba Zarei, Christian Sorg, Alexander Drzezga, Lars Timmermann, Thomas D Meyer, Thilo van Eimeren, Carsten Eggers
Impulsivity and hypomania are common non-motor features in Parkinson's disease (PD). The aim of this study was to find the overlapping and distinct neural correlates of these symptoms in PD. Symptoms of impulsivity and hypomania were assessed in 24 PD patients using the Barratt Impulsiveness Scale (BIS-11) and Self-Report Manic Inventory (SRMI), respectively. In addition, fluorodeoxyglucose positron emission tomography (FDG-PET) imaging for each individual was performed. We conducted two separate multiple regression analyses for BIS-11 and SRMI scores with FDG-PET data to identify the brain regions that are associated with both impulsivity and hypomania scores, as well as those exclusive to each symptom...
January 10, 2018: Brain Imaging and Behavior
https://www.readbyqxmd.com/read/29321714/cavum-vergae-liability-and-steroid-treatment-manic-episode-brain-imaging-findings-and-clinical-follow-up-of-a-systemic-lupus-erythematosus-case
#8
Emre Misir, İbrahim Tolga Binbay, Bilge Targitay, Hidayet Ece Arat, Gerçek Can, Köksal Alptekin
Systemic lupus erythematosus (SLE) or Lupus is a chronic and idiopathic autoimmune connective tissue disease that involves several organs and organ systems. SLE may lead to a group of psychiatric manifestations, including delirium, anxiety disorders, cognitive dysfunction, mood disorders, and psychosis, which are caused by organic or non-organic factors. In addition, it is thought that the most common cause of neuropsychiatric lupus is corticosteroid use; central nervous system involvement and inflammatory processes also have an important role in the development of psychiatric manifestations...
December 2017: Noro Psikiyatri Arsivi
https://www.readbyqxmd.com/read/29318722/tailoring-treatment-dose-according-to-severity-of-manic-symptoms
#9
Chantal Henry
No abstract text is available yet for this article.
January 10, 2018: Bipolar Disorders
https://www.readbyqxmd.com/read/29316081/alterations-of-the-cerebellum-and-basal-ganglia-in-bipolar-disorder-mood-states-detected-by-quantitative-t1%C3%AF-mapping
#10
Casey P Johnson, Gary E Christensen, Jess G Fiedorowicz, Merry Mani, Joseph J Shaffer, Vincent A Magnotta, John A Wemmie
OBJECTIVES: Quantitative mapping of T1 relaxation in the rotating frame (T1ρ) is a magnetic resonance imaging technique sensitive to pH and other cellular and microstructural factors, and is a potentially valuable tool for identifying brain alterations in bipolar disorder. Recently, this technique identified differences in the cerebellum and cerebral white matter of euthymic patients vs healthy controls that were consistent with reduced pH in these regions, suggesting an underlying metabolic abnormality...
January 7, 2018: Bipolar Disorders
https://www.readbyqxmd.com/read/29314557/assessment-of-cognitive-functions-in-bipolar-i-disorder-a-1-year-naturalistic-follow-up-study
#11
Rajesh Sagar, Anamika Sahu, Raman Deep Pattanayak, Biswadip Chatterjee
OBJECTIVE: Available findings from cross-sectional studies have demonstrated cognitive impairments in bipolar I disorder (BD-I) during various phases of illness. However, very little is known about the longitudinal course of these cognitive impairments. The purpose of the study was to explore the longitudinal pattern of changes in cognitive functioning of BD-I patients. METHODS: A total of 129 BD-I subjects (manic, depressed and euthymic groups) and 49 healthy controls were recruited using predefined selection criteria...
January 4, 2018: Bipolar Disorders
https://www.readbyqxmd.com/read/29310066/is-recurrence-in-major-depressive-disorder-related-to-bipolarity-and-mixed-features-results-from-the-bridge-ii-mix-study
#12
Lorenzo Mazzarini, Georgios D Kotzalidis, Daria Piacentino, Salvatore Rizzato, Jules Angst, Jean-Michel Azorin, Charles L Bowden, Sergey Mosolov, Allan H Young, Eduard Vieta, Paolo Girardi, Giulio Perugi
BACKGROUND: Current classifications separate Bipolar (BD) from Major Depressive Disorder (MDD) based on polarity rather than recurrence. We aimed to determine bipolar/mixed feature frequency in a large MDD multinational sample with (High-Rec) and without (Low-Rec) >3 recurrences, comparing the two subsamples. METHODS: We measured frequency of bipolarity/hypomanic features during current depressive episodes (MDEs) in 2347 MDD patients from the BRIDGE-II-mix database, comparing High-Rec with Low-Rec...
January 2, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29309958/no-differences-in-manic-like-behaviors-between-voluntary-ethanol-and-water-drinking-in-lateral-hypothalamic-kindled-lhk-alcohol-preferring-rats
#13
Noha Abdel Gawad, Khalid Mohamed, Doo-Sup Choi, Osama A Abulseoud
This study investigates phenotypic differences of manic-like behaviors during voluntary ethanol (vs. water) intake in alcohol preferring (P) rats, using the lateral hypothalamus kindled (LHK) rat mania model. Alcohol preferring (P) rats exhibited classic manic-like behaviors during kindling and the post-kindling intervals in all coded behaviors (p < 0.0001), lending further validity to the lateral hypothalamus kindled rat as a useful model to study mania. However, there was no significant phenotypic difference between alcohol and water drinking alcohol preferring (P) rats...
January 2, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29308715/exploring-the-relationship-between-vitamin-d-and-mania-correlations-between-serum-vitamin-d-levels-and-disease-activity
#14
Neslihan Altunsoy, Rabia Nazik Yüksel, Merve Cingi Yirun, Ayşegül Kılıçarslan, Çiğdem Aydemir
BACKGROUND: Several studies suggest an association between hypovitaminosis D and mood disorders including major depressive disorder, seasonal affective disorder and premenstrual dysphoric disorder. On the other hand, there is not enough study about acute manic episode and hypovitaminosis D. This data insufficient zone led us to study on whether vitamin D deficiency is associated with acute manic episode and has an impact on disease activity Methods: Thirty-one patients with bipolar disorder in remission, 26 patients with acute manic episode and 40 healthy controls with no major psychopathology were recruited in this study...
January 7, 2018: Nordic Journal of Psychiatry
https://www.readbyqxmd.com/read/29306692/neurocognitive-features-in-clinical-subgroups-of-bipolar-disorder-a-meta-analysis
#15
REVIEW
Emre Bora
OBJECTIVE: There is a significant cognitive heterogeneity in bipolar disorder (BD). The aim of this systematic review was to examine the potential distinctive neuropsychological of features of clinical subgroups of BD. A literature search investigating cognitive differences between potential subtypes of BD was conducted. METHODS: It was possible to conduct a meta-analysis of studies investigating the relationship between cognitive deficits and subgroups of DSM-IV BD (type I (BD-I) and type II (BD-II)), subgroups based on history of psychosis (PBD and NPBD)...
December 29, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29303955/reward-dysfunction-in-the-manic-spectrum-unable-to-win-the-use-of-biographical-information-to-refine-neurobiological-modeling
#16
David A Kahn
OBJECTIVE: The manic spectrum is thought to be characterized by a hypersensitive biobehavioral reward system, the behavioral activation system. Evidence for this framework comes from questionnaire-based, self-report data collected in cross-sectional and prospective studies of mania, mania in remission, and proneness to hypomania, and from functional neuroimaging investigations of brain reward circuit activity during incentivized choice protocols. Although heightened reward anticipation is consistently documented, the status of later goal attainment activity, hedonic responses, and satiety reactions is less clear...
November 2017: Journal of Psychiatric Practice
https://www.readbyqxmd.com/read/29303954/reward-dysfunction-in-the-manic-spectrum-unable-to-win-the-use-of-biographical-information-to-refine-neurobiological-modeling
#17
John F Gottlieb
OBJECTIVE: The manic spectrum is thought to be characterized by a hypersensitive biobehavioral reward system, the behavioral activation system. Evidence for this framework comes from questionnaire-based, self-report data collected in cross-sectional and prospective studies of mania, mania in remission, and proneness to hypomania, and from functional neuroimaging investigations of brain reward circuit activity during incentivized choice protocols. Although heightened reward anticipation is consistently documented, the status of later goal attainment activity, hedonic responses, and satiety reactions is less clear...
November 2017: Journal of Psychiatric Practice
https://www.readbyqxmd.com/read/29291581/analysis-on-speech-signal-features-of-manic-patients
#18
Jing Zhang, Zhongde Pan, Chao Gui, Ting Xue, Yezhe Lin, Jie Zhu, Donghong Cui
Given the lack of effective biological markers for early diagnosis of bipolar mania, and the tendency for voice fluctuation during transition between mood states, this study aimed to investigate the speech features of manic patients to identify a potential set of biomarkers for diagnosis of bipolar mania. 30 manic patients and 30 healthy controls were recruited and their corresponding speech features were collected during natural dialogue using the Automatic Voice Collecting System. Bech-Rafaelsdn Mania Rating Scale (BRMS) and Clinical impression rating scale (CGI) were used to assess illness...
December 22, 2017: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/29290022/omega-3-fatty-acids-supplementation-with-lithium-and-aripiprazole-for-improving-the-balance-of-circulating-hormones-and-brain-neurotransmitters-in-manic-mice-model
#19
Pandiyan Arunagiri, Elumalai Balamurugan, Murugesan Saravanakumar, Mackraj Irene
The present study was designed to evaluate the combined effect of lithium and aripiprazole supplemented with omega-3 fatty acids in methylphenidate (MPD)-induced manic mice. Swiss albino mice were administered with MPD or saline for 14 days, and based on changes in behavioral activities animals were treated with lithium, aripiprazole, and omega-3 fatty acids from the 8th day. Behavioral patterns were analyzed by video tracking. Thyroxine, follicle-stimulating hormone (FSH), luteinizing hormone (LH), and testosterone levels were assayed in serum using ELISA kits...
December 30, 2017: Naunyn-Schmiedeberg's Archives of Pharmacology
https://www.readbyqxmd.com/read/29289701/dopamine-transporter-knockdown-mice-in-the-behavioral-pattern-monitor-a-robust-reproducible-model-for-mania-relevant-behaviors
#20
Molly A Kwiatkowski, Gerhard Hellemann, Catherine A Sugar, Zackary A Cope, Arpi Minassian, William Perry, Mark A Geyer, Jared W Young
Efforts to replicate results from both basic and clinical models have highlighted problems with reproducibility in science. In psychiatry, reproducibility issues are compounded because the complex behavioral syndromes make many disorders challenging to model. We develop translatable tasks that quantitatively measure psychiatry-relevant behaviors across species. The behavioral pattern monitor (BPM) was designed to analyze exploratory behaviors, which are altered in patients with bipolar disorder (BD), especially during mania episodes...
December 28, 2017: Pharmacology, Biochemistry, and Behavior
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