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Child Arthritis

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https://www.readbyqxmd.com/read/29780794/pediatric-scurvy-when-contemporary-eating-habits-bring-back-the-past
#1
Alice Brambilla, Cristina Pizza, Donatella Lasagni, Lucia Lachina, Massimo Resti, Sandra Trapani
Vitamin C deficiency is anecdotal in developed countries, mainly associated with underling clinical morbidities as autism or neurological impairment. Chronic insufficient dietary supply is responsible for vascular fragility and impaired bone formation, resulting in gingival bleeding, petechial lesions, articular and bone pain or limb swelling. Children may present anorexia, irritability, failure to thrive, limping or refusal to walk. Accordingly, pediatric scurvy is frequently misdiagnosed with osteomyelitis, septic arthritis, bone and soft tissue tumor, leukemia, bleeding disorders, and rheumatologic conditions...
2018: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/29773450/acromioclavicular-joint-septic-arthritis-in-an-immunocompetent-child-a-case-report
#2
Saurabh Dutt, Jeetendra Lodhi, Vinod Kumar, Abhishek Kashyap
Septic arthritis of acromioclavicular (AC) joint is a rare entity. It is generally seen in patients who are immunocompromised. Only 15 cases have been reported till now, with only one case series of 6 patients. We report a case of septic arthritis of AC joint in an immunocompetent child. A 9 years old girl presented with history of pain in left shoulder for 4 days associated with fever. No history suggestive of any immunocompromised state was complained. On local examination, a swelling of around 3 cm in diameter was found over left AC joint region with raised local temperature, tenderness on palpation and positive response in fluctuation test...
March 23, 2018: Chinese Journal of Traumatology, Zhonghua Chuang Shang za Zhi
https://www.readbyqxmd.com/read/29766250/juvenile-idiopathic-arthritis-the-role-of-imaging-from-a-rheumatologist-s-perspective
#3
REVIEW
Clara Malattia, Nikolay Tzaribachev, J Merlijn van den Berg, Silvia Magni-Manzoni
Alongside recent advances in treatment strategies for juvenile idiopathic arthritis (JIA), paediatric rheumatologists have taken increasing interest in the use of imaging. Magnetic resonance imaging (MRI) and musculoskeletal ultrasound, by providing more detailed information on disease activity than clinical examination and conventional radiography (CR), have become helpful diagnostic and managerial tools. The growing skeleton, however, with changing appearances over time, is still challenging in the establishment of valid scoring systems for pathological changes...
June 2018: Pediatric Radiology
https://www.readbyqxmd.com/read/29766247/current-status-of-wrist-imaging-in-juvenile-idiopathic-arthritis
#4
REVIEW
Derk Frederik Matthaus Avenarius, Charlotte Nusman, Clara Malattia, Laura Tanturri de Horatio, Karen Rosendahl, Mario Maas, Lil-Sofie Ording Müller
Wrist involvement occurs in about one-quarter of patients diagnosed with juvenile idiopathic arthritis (JIA), increasing to 40% 5 years after diagnosis. The imaging appearances, both for active inflammation and permanent change, differ from those seen in adult rheumatoid arthritis; therefore, a child-specific approach is crucial for correct assessment. In this review article, we provide an update on the current status for imaging wrist JIA, with a focus on evidence-based practice.
June 2018: Pediatric Radiology
https://www.readbyqxmd.com/read/29731173/child-mortality-in-england-compared-with-sweden-a-birth-cohort-study
#5
Ania Zylbersztejn, Ruth Gilbert, Anders Hjern, Linda Wijlaars, Pia Hardelid
BACKGROUND: Child mortality is almost twice as high in England compared with Sweden. We aimed to establish the extent to which adverse birth characteristics and socioeconomic factors explain this difference. METHODS: We developed nationally representative cohorts of singleton livebirths between Jan 1, 2003, and Dec 31, 2012, using the Hospital Episode Statistics in England, and the Swedish Medical Birth Register in Sweden, with longitudinal follow-up from linked hospital admissions and mortality records...
May 3, 2018: Lancet
https://www.readbyqxmd.com/read/29724248/predicting-unfavorable-long-term-outcome-in-juvenile-idiopathic-arthritis-results-from-the-nordic-cohort-study
#6
Veronika Rypdal, Ellen Dalen Arnstad, Kristiina Aalto, Lillemor Berntson, Maria Ekelund, Anders Fasth, Mia Glerup, Troels Herlin, Susan Nielsen, Suvi Peltoniemi, Marek Zak, Marite Rygg, Martin Rypdal, Ellen Nordal
BACKGROUND: The aim was to develop prediction rules that may guide early treatment decisions based on baseline clinical predictors of long-term unfavorable outcome in juvenile idiopathic arthritis (JIA). METHODS: In the Nordic JIA cohort, we assessed baseline disease characteristics as predictors of the following outcomes 8 years after disease onset. Non-achievement of remission off medication according to the preliminary Wallace criteria, functional disability assessed by Childhood Health Assessment Questionnaire (CHAQ) and Physical Summary Score (PhS) of the Child Health Questionnaire, and articular damage assessed by the Juvenile Arthritis Damage Index-Articular (JADI-A)...
May 3, 2018: Arthritis Research & Therapy
https://www.readbyqxmd.com/read/29707409/juvenile-idiopathic-arthritis-associated-with-combined-jp-hht-syndrome-a-novel-phenotype-associated-with-a-novel-variant-in-smad4
#7
Juliet Chhay Bishop, Jacquelyn Francis Britton, Anne M Murphy, Sangeeta Sule, Sally Mitchell, Clifford Takemoto, Joseph M Collaco, Wikrom Karnsakul, Carmelo Cuffari, Edith Dietz, Joann Bodurtha
Juvenile polyposis (JP) syndrome is characterized by multiple hamartomatous polyps of the gastrointestinal tract. Hereditary hemorrhagic telangiectasia (HHT) is a vascular dysplasia characterized by telangiectasia in the skin, mucous membranes, and arteriovenous malformations in other organs. Individuals with JP-HHT syndrome have variable features of both rare disorders, attributed to heterozygous mutations in the SMAD4 gene. Systemic juvenile idiopathic arthritis (JIA) is a severe, chronic disease marked by arthritis and systemic inflammation for which the cause remains unknown...
June 2018: Journal of Pediatric Genetics
https://www.readbyqxmd.com/read/29695255/temporomandibular-joint-arthritis-in-juvenile-idiopathic-arthritis-now-what
#8
REVIEW
Matthew L Stoll, Chung H Kau, Peter D Waite, Randy Q Cron
BACKGROUND: Arthritis involving the temporomandibular joint (TMJ) complicates 40 - 96% of cases of juvenile idiopathic arthritis (JIA), potentially leading to devastating changes to form and function. Optimal evaluation and management of this joint remains a matter of ongoing discussion. METHODS: We performed a PubMed search for all articles with keywords "temporomandibular" and "arthritis", covering the dates 2002 through February 28, 2018. A separate PubMed search was performed for all articles with keywords "temporomandibular joint", "arthritis", and "treatment" covering the same dates...
April 25, 2018: Pediatric Rheumatology Online Journal
https://www.readbyqxmd.com/read/29675757/fetal-methotrexate-syndrome-and-antley-bixler-syndrome-should-not-be-confused
#9
REVIEW
C Richards, Christine M Hall, D Johnson, Amaka C Offiah
Exposure to methotrexate in utero can result in fetal methotrexate syndrome - a condition characterised by prenatal-onset growth retardation, craniosynostosis, dysmorphic facies and multiple limb abnormalities. A literature review was prompted by the findings in a girl who is presented here with full consent from her guardian. She is the third child of unrelated parents and was 4 years old at the time of this report. Her mother took 15 mg methotrexate on two occasions during early pregnancy for juvenile idiopathic arthritis, unaware that she was pregnant...
April 19, 2018: Pediatric Radiology
https://www.readbyqxmd.com/read/29652976/-escherichia-vulneris-etiologic-agent-of-septic-arthritis-in-a-child
#10
Carla Pérez, Paulo Melo, Javier Besomi, Lorena Porte, Jan Paul Wilhelm
Escherichia vulneris is a gram-negative bacillus that belongs to the family Enterobacteriaceae, with a questioned pathogenic role. However, it has been confirmed as the cause of wound infections. We report the case of a 12-year-old girl, previously healthy, with a diagnosis of septic arthritis of the right knee, secondary to a spinal lesion. Escherichia vulneris, an unusual etiology of septic arthritis in children, was isolated in the joint fluid. This case is one of the first cases of septic arthritis due to E...
2018: Revista Chilena de Infectología: órgano Oficial de la Sociedad Chilena de Infectología
https://www.readbyqxmd.com/read/29645010/adding-patient-reported-outcomes-to-a-multisite-registry-to-quantify-quality-of-life-and-experiences-of-disease-and-treatment-for-youth-with-juvenile-idiopathic-arthritis
#11
Elissa R Weitzman, Lauren E Wisk, Parissa K Salimian, Kara M Magane, Fatma Dedeoglu, Aimee O Hersh, Yukiko Kimura, Kenneth D Mandl, Sarah Ringold, Marc Natter
Background: Children with Juvenile Idiopathic Arthritis (JIA) often have poor health-related quality of life (HRQOL) despite advances in treatment. Patient-centered research may shed light on how patient experiences of treatment and disease contribute to HRQOL, pinpointing directions for improving care and enhancing outcomes. Methods: Parent proxies of youth enrolled in the Childhood Arthritis and Rheumatology Research Alliance (CARRA) Registry shared patient-reported outcomes about their child's HRQOL and experiences of disease and treatment burden (pain interference, morning stiffness, history of medication side effects and methotrexate intolerance)...
2018: Journal of patient-reported outcomes
https://www.readbyqxmd.com/read/29643731/childhood-pyogenic-osteomyelitis-in-abakaliki-south-east-nigeria
#12
Njoku Isaac Omoke
Background: Pyogenic osteomyelitis is an important child health problem in developing countries. It is a one-disease state with a spectrum of pathological features and clinical forms ranging from acute to chronic presentation. Its pattern of presentation varies from and within subregions. The aim of this study was to determine the pattern and outcome of childhood pyogenic osteomyelitis in a low-resource environment. Materials and Methods: This was a retrospective study of all the children aged 18 years and under seen with pyogenic osteomyelitis in Federal Teaching Hospital Abakaliki between January 2005 and December 2015...
January 2018: Nigerian Journal of Surgery: Official Publication of the Nigerian Surgical Research Society
https://www.readbyqxmd.com/read/29600940/the-burden-of-systemic-juvenile-idiopathic-arthritis-for-patients-and-caregivers-an-international-survey-and-retrospective-chart-review
#13
Susan Shenoi, Gerd Horneff, Michal Cidon, Athimalaipet V Ramanan, Yukiko Kimura, Pierre Quartier, Ivan Foeldvari, Andrew Zeft, Kathleen G Lomax, Jill Gregson, Tineke Abma, Sarah Campbell-Hill, Jeffrey Weiss, Dony Patel, Nina Marinsek, Nico Wulffraat
OBJECTIVES: To investigate the burden of systemic juvenile idiopathic arthritis (SJIA) on health-related quality of life (HRQOL) and resource use of patients and caregivers (families) on biologic therapy. METHODS: This international study assessed SJIA burden in patients on biologics, using a caregiver questionnaire and retrospective chart review. Validated measures included: Child Health Questionnaire Parent-Form 50 (CHQ-PF50), 36-Item Short-Form Health Survey (SF-36v2) and Work Productivity and Activity Impairment questionnaire: Specific Health Problem (WPAI:SHP)...
March 21, 2018: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/29545432/carpal-synovitis-with-capitate-bone-tuberculosis-in-a-child
#14
André Grenho, Joana Arcângelo, Pedro Jordão, Catarina Gouveia
We present a 10-year-old boy with 2-month duration non-traumatic wrist pain and inflammatory signs. Due to elevated inflammatory markers on blood tests, with an increase in radiocarpal and intercarpal joints synovial fluid and no bony lesions, the patient was submitted to wrist arthrocentesis for the suspicion of septic arthritis. The patient did not improve on conventional treatment, however. An MRI showed synovitis around the carpus and a lytic lesion of the capitate bone due to osteomyelitis. A biopsy was able to identify the causative agent as Mycobacterium tuberculosis , and the patient was treated with antibiotics...
March 15, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29507023/-kingella-kingae-sternoclavicular-osteoarthritis
#15
Sérgio Alves, Lúcia Rodrigues, Mafalda Santos, Diana Moreira
Sternoclavicular arthritis is an unusual osteoarticular infection and can be associated with severe complications. Cases in a paediatric population are infrequently reported, making this approach challenging. Kingella kingae is an agent of increasing recognition in paediatric invasive infections, principally below 2 years of age. A case of K. kingae osteoarthritis in a 17-month-old child is described with a review of the literature.
March 5, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29480358/living-with-juvenile-idiopathic-arthritis-parent-and-physician-perspectives
#16
Shelly Heath-Watson, Sangeeta Sule
This article, co-authored by a parent of a child with juvenile idiopathic arthritis (JIA) and his pediatric rheumatologist, discusses the parent's experience of having a child with JIA from diagnosis through living day-to-day with the disease.
June 2018: Rheumatology and Therapy
https://www.readbyqxmd.com/read/29427642/germline-gain-of-function-myeloid-differentiation-primary-response-gene-88-myd88-mutation-in-a-child-with-severe-arthritis
#17
Keith A Sikora, Joshua R Bennett, Laurens Vyncke, Zuoming Deng, Wanxia Li Tsai, Ewald Pauwels, Gerlinde Layh-Schmitt, April Brundidge, Fatemeh Navid, Kristien J M Zaal, Eric Hanson, Massimo Gadina, Louis M Staudt, Thomas A Griffin, Jan Tavernier, Frank Peelman, Robert A Colbert
No abstract text is available yet for this article.
February 7, 2018: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/29419467/barriers-to-adherence-in-juvenile-idiopathic-arthritis-a-multicenter-collaborative-experience-and-preliminary-results
#18
Leslie A Favier, Janalee Taylor, Kristin Loiselle Rich, Karla B Jones, Sheetal S Vora, Julia G Harris, Beth S Gottlieb, Lisa Robbins, Jamie T Lai, Tzielan Lee, Melanie Kohlheim, Jennifer Gill, Laura Bouslaugh, Angela Young, Nancy Griffin, Esi M Morgan, Avani C Modi
OBJECTIVE: Nonadherence is currently an underrecognized and potentially modifiable obstacle to care in juvenile idiopathic arthritis (JIA). The purpose of our study was to design and implement a standardized approach to identifying adherence barriers for youth with JIA across 7 pediatric rheumatology clinics through the Pediatric Rheumatology Care and Outcomes Improvement Network (PR-COIN) and to assess the frequency of adherence barriers in patients and their caregivers across treatment modalities...
February 1, 2018: Journal of Rheumatology
https://www.readbyqxmd.com/read/29393540/serogroup-y-primary-meningococcal-arthritis-in-a-child
#19
Claudia O'Rourke, Mark Garden, Patrick Joyce, Thomas Pagliaro, Hamish Gray, Kathryn Wilks
No abstract text is available yet for this article.
February 2, 2018: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/29301763/mental-disorder-in-children-with-physical-conditions-a-pilot-study
#20
Alexandra Butler, Ryan J Van Lieshout, Ellen Louise Lipman, Harriet L MacMillan, Andrea Gonzalez, Jan Willem Gorter, Kathy Georgiades, Kathy N Speechley, Michael H Boyle, Mark A Ferro
OBJECTIVES: Methodologically, to assess the feasibility of participant recruitment and retention, as well as missing data in studying mental disorder among children newly diagnosed with chronic physical conditions (ie, multimorbidity). Substantively, to examine the prevalence of multimorbidity, identify sociodemographic correlates and model the influence of multimorbidity on changes in child quality of life and parental psychosocial outcomes over a 6-month follow-up. DESIGN: Prospective pilot study...
January 3, 2018: BMJ Open
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