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Psychiatric pharmacy

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https://www.readbyqxmd.com/read/27905161/the-impact-of-co-morbidity-burden-on-appropriate-implantable-cardioverter-defibrillator-therapy-and-all-cause-mortality-insight-from-danish-nationwide-clinical-registers
#1
Anne Christine Ruwald, Michael Vinther, Gunnar H Gislason, Jens Brock Johansen, Jens Cosedis Nielsen, Helen Høgh Petersen, Sam Riahi, Christian Jons
AIMS: In a nationwide cohort of primary (PP-ICD) and secondary prevention (SP-ICD) implantable cardioverter defibrillator (ICD) patients, we aimed to investigate the association between co-morbidity burden and risk of appropriate ICD therapy and mortality. METHODS AND RESULTS: We identified all patients >18 years, implanted with first-time PP-ICD (n = 1873) or SP-ICD (n = 2461) in Denmark from 2007 to 2012. Co-morbidity was identified in administrative registers of hospitalization and drug prescription from pharmacies...
December 1, 2016: European Journal of Heart Failure
https://www.readbyqxmd.com/read/27832054/epilepsy-among-iraq-and-afghanistan-war-veterans-united-states-2002-2015
#2
Mary Jo Pugh, Anne C Van Cott, Megan Amuan, Christine Baca, Paul Rutecki, Matthew M Zack, Rosemarie Kobau
The age-adjusted prevalence of seizure disorder in United States veterans deployed in Iraq and Afghanistan conflicts (IAV) is 6.1 per 1,000 persons (1), compared with 7.1 to 10 per 1,000 persons in the general population (2,3). Persons with epilepsy are at risk of excess mortality in part because of comorbidity (4). Although patterns of comorbidity have been associated with mortality in IAV (5), the unique contribution of epilepsy to excess mortality in IAV is unknown. A cohort study was developed using inpatient, outpatient, and pharmacy data from the U...
November 11, 2016: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/27783555/integrated-pharmacies-at-community-mental-health-centers-medication-adherence-and-outcomes
#3
W Abel Wright, Jack M Gorman, Melissa Odorzynski, Mark J Peterson, Carol Clayton
BACKGROUND: Patients receiving psychiatric services at community mental health centers (CMHCs) are often prescribed medication that is critical to the treatment of behavioral health conditions, including schizophrenia, bipolar disorder, anxiety, and depression. Previous studies have shown correlation between rates of medication adherence and risk of hospitalization, but potential differences in medication adherence and other outcomes for patients of CMHCs by pharmacy type have not been widely studied...
November 2016: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/27744463/patients-reasons-for-obtaining-psychotropic-medications-without-a-prescription-at-retail-pharmacies-in-central-saudi-arabia
#4
Fahad D Alosaimi, Fay S Alruwais, Fadah A Alanazi, Ghaida A Alabidi, Nadia A Aljomah, Nuha S Alsalameh
OBJECTIVE: To explore the possible causes behind adults seeking psychotropic medications without a prescription; identify the most commonly used psychotropic medications without a prescription; and determine the prevalence of depression and anxiety disorders among adults who used psychotropic medications without a prescription in Riyadh, Kingdom of Saudi Arabia. METHODS: A cross-sectional study was conducted from November 2014 to August 2015. A convenience sample was taken by distributing a self-administered questionnaire among participants who had obtained psychotropic medications without a prescription from retail pharmacies during the 4 weeks prior to study intake in Riyadh, Kingdom of Saudi Arabia...
October 2016: Neurosciences: the Official Journal of the Pan Arab Union of Neurological Sciences
https://www.readbyqxmd.com/read/27708675/uptake-of-the-medscheck-annual-medication-review-service-in-ontario-community-pharmacies-between-2007-and-2013
#5
Lisa Dolovich, Giulia Consiglio, Linda MacKeigan, Lusine Abrahamyan, Petros Pechlivanoglou, Valeria E Rac, Nedzad Pojskic, Elizabeth A Bojarski, Jiandong Su, Murray Krahn, Suzanne M Cadarette
BACKGROUND: MedsCheck Annual (MCA) is an Ontario government-funded medication review service for individuals taking 3 or more prescription medications for chronic conditions. METHODS: This cohort study analyzed linked administrative claims data from April 1, 2007, to March 31, 2013. Trends in MCA claims and recipient characteristics were examined. RESULTS: A total of 1,498,440 Ontarians (55% seniors, 55% female) received an MCA. One-third (36%) had 2 or more MCAs within 6 years...
September 2016: Canadian Pharmacists Journal: CPJ, Revue des Pharmaciens du Canada: RPC
https://www.readbyqxmd.com/read/27686282/electrocardiographic-surveillance-in-a-psychiatric-institution-avoiding-iatrogenic-cardiovascular-death
#6
Cristobal Manuel Rodríguez-Leal, Elena López-Lunar, Jose Manuel Carrascosa-Bernáldez, Rosa Maria Provencio-Arranz
OBJECTIVE: To describe a new initiative developed to optimise patient safety in a mental health setting in order to prevent serious cardiac events. MATERIALS AND METHODS: A longitudinal study of all in-patients admitted at the hospital, comprised of 197 beds distributed among three units, was conducted for 12 months. All admitted patients at the hospital underwent electrocardiogram surveillance, as it was described in our new local guideline for sudden cardiac death prevention...
September 30, 2016: International Journal of Psychiatry in Clinical Practice
https://www.readbyqxmd.com/read/27670738/transforming-health-care-through-interprofessional-graduate-education
#7
Lora Humphrey Beebe, Marian Roman, Hollie Raynor, Dixie Thompson, Shaunta Ray
PURPOSE: We provide an overview of the Recovery-based Interprofessional Distance Education (RIDE) rotation for graduate students in psychiatric mental health (PMH) nursing, pharmacy, nutrition, and exercise physiology, with faculty from the four professions represented. CONCLUSIONS: Interprofessional education can enhance team concepts in these professions and is viewed positively by students and faculty. PRACTICE IMPLICATIONS: Interprofessional learning opportunities prepare graduates to contribute to team-based care...
September 27, 2016: Perspectives in Psychiatric Care
https://www.readbyqxmd.com/read/27555821/pharmacist-remote-review-of-medication-prescriptions-for-appropriateness-in-pediatric-intensive-care-unit
#8
Moran Lazaryan, Ibrahim Abu-Kishk, Noa Rosenfeld-Yehoshua, Sofia Berkovitch, Michal Toledano, Iris Reshef, Tal Kanari, Tomer Ziv-Baran, Matitiahu Berkovitch
BACKGROUND: One aspect of ordering and prescribing medication is the requirement for a trained professional to review medication orders or prescriptions for appropriateness. In practice, this review process is usually performed by a clinical pharmacist. However, in many medical centers there is a shortage of staff and a pharmacist is not always available. OBJECTIVE: To determine whether remote review of medication orders by a pharmacist is a plausible method in a pediatric intensive care unit (PICU)...
2016: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/27356195/managed-care-aspects-of-psoriasis-and-psoriatic-arthritis
#9
Colby Evans
The chronic and systemic nature of psoriasis has a significant impact on direct costs, indirect costs, and patient quality of life. Psoriasis is associated with comorbid conditions that add to the burden of the disease, especially in moderate to severe disease. The total estimated annual healthcare burden of psoriasis may be as high as $35.2 billion, with $12.2 billion in direct costs and $23 billion in indirect costs (attributed to reduced health-related quality of life and lost productivity). These costs vary based on the severity of the disease; pharmacy costs account for the majority of the burden, especially in severe disease...
June 2016: American Journal of Managed Care
https://www.readbyqxmd.com/read/27310244/interprovincial-variation-in-antipsychotic-and-antidepressant-prescriptions-dispensed-in-the-canadian-pediatric-population
#10
Nikita Arora, Sandra Knowles, Tara Gomes, Muhammad M Mamdani, David N Juurlink, Corine Carlisle, Mina Tadrous
OBJECTIVE: Although antidepressants and antipsychotics are valuable medications in the treatment of select psychiatric disorders, there is increasing focus on the balance of risks and benefits of these drugs as prescribed, particularly in the pediatric population. We examined recent national trends and interprovincial variation in dispensing of antipsychotic and antidepressant prescriptions to the Canadian pediatric population. METHOD: We conducted a population-based cross-sectional study of antidepressant and antipsychotic prescriptions dispensed by Canadian pharmacies to the pediatric population (≤18 years) between 2010 and 2013...
May 12, 2016: Canadian Journal of Psychiatry. Revue Canadienne de Psychiatrie
https://www.readbyqxmd.com/read/27147215/visual-hallucinations-associated-with-gabapentin-use
#11
Katelyn A Parsons, Michael E Derkits
PURPOSE: A case of probable gabapentin-induced visual hallucinations in a patient with no psychiatric history is reported. SUMMARY: A 65-year-old white woman with no history of psychiatric conditions arrived at the pharmacy clinic with specific complaints of daytime sleepiness, fatigue, and visual hallucinations that started after coronary artery bypass graft surgery three years prior. After the surgery she began experiencing neuropathic pain in her chest, which was treated with gabapentin...
May 15, 2016: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/27114739/inpatient-resource-use-and-costs-associated-with-switching-from-oral-antipsychotics-to-aripiprazole-once-monthly-for-the-treatment-of-schizophrenia
#12
Michele Wilson, Benjamin Gutierrez, Steve J Offord, Christopher M Blanchette, Anna Eramo, Stephanie Earnshaw, Siddhesh A Kamat
BACKGROUND: Schizophrenia is associated with high direct healthcare costs due to progression of disease and frequent occurrence of relapses. Aripiprazole once-monthly (AOM) has been shown to reduce total psychiatric hospitalizations among patients who switched from oral standard of care (SOC) therapy to AOM in a multicenter, open-label, mirror-image study of patients with schizophrenia. Because of the increasing need to improve patient outcomes while containing costs, it is important to understand the impact of AOM treatment initiation on medical costs associated with psychiatric hospitalizations and antipsychotic pharmacy costs...
2016: Drugs in Context
https://www.readbyqxmd.com/read/27090792/modulation-of-energy-intake-and-expenditure-due-to-habitual-physical-exercise
#13
REVIEW
Matoulek Martin, Slaby Krystof, Radvansky Jiri, Dankova Martina, Vetrovska Renata, Mikes Ondrej, Svacina Stepan, Tuka Vladimir
BACKGROUND: The 20th and 21st centuries are marked by an increase in life expectancy on one hand and on the other hand by the increase of so called civilization diseases. Their share one common trait: the energy metabolism imbalance, with low energy expenditure and high energy uptake. Our age can be viewed as the age of inactivity and wealth. METHODS: The aim of the present review is to highlight the influence of habitual physical activity on energy metabolism and balance...
2016: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/26982632/stimulant-treatment-of-young-people-in-the-united-states
#14
Mark Olfson, Marissa King, Michael Schoenbaum
OBJECTIVE: To describe national stimulant treatment patterns among young people focusing on patient age and prescribing specialty. METHODS: Stimulant prescriptions to patients aged 3-24 were analyzed from the 2008 IMS LifeLink LRx Longitudinal Prescription database (n = 3,147,352), which includes 60% of all U.S. retail pharmacies. A subset of young people from 2009 with service claims (n = 197,654) were also analyzed. Denominators were adjusted to generalize estimates to the U...
August 2016: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/26950309/demographic-and-clinical-predictors-of-high-healthcare-use-in-patients-with-inflammatory-bowel-disease
#15
Benjamin Click, Claudia Ramos Rivers, Ioannis E Koutroubakis, Dmitriy Babichenko, Alyce M Anderson, Jana G Hashash, Michael A Dunn, Marc Schwartz, Jason Swoger, Leonard Baidoo, Arthur Barrie, Miguel Regueiro, David G Binion
BACKGROUND: Inflammatory bowel disease (IBD) is a heterogeneous chronic inflammatory condition requiring significant healthcare expenditure. Subgroups of individuals contribute disproportionately to spending. We aimed to determine demographic and clinical factors predictive of high healthcare expenditures for IBD patients followed over a multiyear period. METHODS: This was a registry analysis using a prospective observational, consented, natural history registry from a tertiary IBD center and associated medical charges, not including pharmacy expenses...
June 2016: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/26894929/serum-ferritin-weight-gain-disruptive-behavior-and-extrapyramidal-symptoms-in-risperidone-treated-youth
#16
Chadi A Calarge, Daryl J Murry, Ekhard E Ziegler, L Eugene Arnold
BACKGROUND: Iron deficiency disrupts dopaminergic signaling in rodents, resulting in cognitive deficits that may be reversed with psychostimulants. In humans, iron deficiency with or without anemia has similarly been found to cause neuropsychological and behavioral impairments. However, the clinical effects of low body iron stores in antipsychotic-treated children have not been examined. METHODS: Medically healthy, 5- to 17-year-old boys treated with risperidone for at least 1 year were enrolled between February 2009 and November 2013 in a multiphase study, examining the skeletal effects of calcium and vitamin D supplementation in risperidone-induced hyperprolactinemia...
June 2016: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/26780201/-evaluation-of-therapeutical-appropriateness-in-psychiatric-treatment-of-schizophrenia-by-integrating-computer-data-records-with-clinical-audit-results
#17
Giuseppina Farina, Enrica Menditto, Gabriella Corea, Sonia Manna, Claudia Pagliaro, Chiara Troncone, Claudio Linguiti, Valentina Orlando, Daria Putignano, Daniele Ugo Tari, Gianfranco Buffardi
AIM: The aim is to evaluate prescriptive patterns of atypical antipsychotic drugs for the treatment of schizophrenia in the LHU Caserta in 2011-2013, and to indicate potentially inappropriate therapy; to plan or schedule corrective/preventive activities to support the continuous improvement of health services. METHODS: Retrospective cohort study, based on integration of health records and clinical audit. The study was performed in the following steps: data retrieval and analysis; comparison of data with international literature; editing of the Diagnostic-Therapeutic Path...
November 2015: Rivista di Psichiatria
https://www.readbyqxmd.com/read/26721613/risk-factors-of-prescription-opioid-overdose-among-colorado-medicaid-beneficiaries
#18
Piyameth Dilokthornsakul, Gina Moore, Jonathan D Campbell, Robert Lodge, Cathy Traugott, Judy Zerzan, Richard Allen, Robert L Page
UNLABELLED: This study aims to determine risk factors of opioid overdose among the Colorado Medicaid population. A retrospective nested case-control study was undertaken. Medicaid beneficiaries who had ≥1 medical claim for an emergency department visit or a hospitalization associated with an opioid overdose from July 2009 to June 2014 were defined as cases. Controls were selected using a nearest neighbor matching without replacement. The matched controls were selected on the basis of age, sex, and opioid prescription...
April 2016: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/26683680/cost-avoidance-and-qualitative-analysis-of-clinical-pharmacy-interventions-by-psychiatric-pharmacy-residents-at-state-psychiatric-facilities
#19
Kristen N Gardner, Lauren A Diefenderfer, Leigh Anne Nelson, Courtney Iuppa, Ellie Elliott, Kalee Kleinhesselink, Debbie Sass, Roger W Sommi
PURPOSE: The cost avoidance and quality of clinical interventions made by postgraduate year 2 (PGY2) psychiatric pharmacy residents are analyzed. METHODS: A retrospective database review of clinical interventions made by PGY2 psychiatric pharmacy residents in two state psychiatric facilities from July 1, 2007 through June 30, 2014, was conducted using a clinical intervention documentation software system. Cost avoidance was calculated by multiplying the mean cost of an adverse drug reaction (ADR) by the probability of an ADR occurring had the intervention not occurred...
January 1, 2016: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/26672504/-research-in-psychopharmacology
#20
Alejandro Ferrero
Research in psychopharmacology began around 1950 with the description of antipsychotic effect of chlorpromazine followed shortly later with the mechanism of action of antidepressants. In these initial phases, pharmacy industry was open to knowledge and made efforts tending to the development to new drugs that showed efficacy and good safety profiles. In parallel development of theories attempting to find the etiology of psychiatric disorders acquired impulse. This review summarizes the new drugs for the treatment of psychiatric disorders currently under development and also presents a short list of the main biomarkers proposed for the diagnosis or the comprehension of the etiopathogeny in Psychiatry...
July 2015: Vertex: Revista Argentina de Psiquiatriá
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