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https://www.readbyqxmd.com/read/28734184/an-empirical-review-of-potential-mediators-and-mechanisms-of-prolonged-exposure-therapy
#1
REVIEW
Andrew A Cooper, Erin G Clifton, Norah C Feeny
Prolonged exposure (PE) is an empirically-supported treatment for posttraumatic stress disorder (PTSD), but the precise mechanism(s) by which PE promotes symptom change are not well established. Understanding how PE works is critical to improving clinical outcomes, advancing dissemination efforts, and enhancing transdiagnostic models of psychopathology. However, mechanisms research conducted in clinical treatment settings is complex, and findings may be difficult to interpret without appropriate context. This is the first review of potential mechanisms of PE to provide such context, by rigorously evaluating empirical findings in line with essential criteria for effective research on mechanisms (or mediators)...
July 11, 2017: Clinical Psychology Review
https://www.readbyqxmd.com/read/28732289/effects-of-psychotherapies-for-posttraumatic-stress-disorder-on-sleep-disturbances-results-from-a-randomized-clinical-trial
#2
Elizabeth Woodward, Ann Hackmann, Jennifer Wild, Nick Grey, David M Clark, Anke Ehlers
The effectiveness and mechanisms of psychotherapies for posttraumatic stress disorder (PTSD) in treating sleep problems is of interest. This study compared the effects of a trauma-focused and a non-trauma-focused psychotherapy on sleep, to investigate whether 1) sleep improves with psychotherapy for PTSD; 2) the degree of sleep improvement depends on whether the intervention is trauma or nontrauma-focused; 3) the memory-updating procedure in cognitive therapy for PTSD (CT-PTSD) is associated with sleep improvements; 4) initial sleep duration affects PTSD treatment outcome; and 5) which symptom changes are associated with sleep duration improvements...
July 8, 2017: Behaviour Research and Therapy
https://www.readbyqxmd.com/read/28728642/a-latent-profile-analysis-of-aggression-and-victimization-across-relationship-types-among-veterans-who-use-substances
#3
RaeAnn E Anderson, Erin E Bonar, Maureen A Walton, Jason E Goldstick, Sheila A M Rauch, Quyen M Epstein-Ngo, Stephen T Chermack
OBJECTIVE: This study examined patterns of violence victimization and aggression in both intimate partner and nonpartner relationships among U.S. military veterans using latent profile analysis to identify subtypes of violence involvement. METHOD: Participants were 839 substance use treatment-seeking veterans (93% male) from a large Veterans Affairs Medical Center who completed screening measures for a randomized controlled trial. RESULTS: Past-year violence involvement, including both intimate partner violence (IPV) and nonpartner violence (NPV), was common in the sample, although NPV occurred at somewhat higher rates...
July 2017: Journal of Studies on Alcohol and Drugs
https://www.readbyqxmd.com/read/28728063/factors-associated-with-non-return-to-work-in-the-severely-injured-victims-3-years-after-a-road-accident-a-prospective-study
#4
C Pélissier, E Fort, L Fontana, B Charbotel, M Hours
Road accidents may impact victims' physical and/or mental health and socio-occupational life, particularly the capacity to return to work. The purpose of our study is to assess modifiable medical and socio-occupational factors of non-return to work in the severely injured 3 years after a road accident. Among1,168 road accidents casualties in the Rhône administrative Département of France followed for five years, 141 of the 222 severely injured (Maximal Abbreviated Injury Scale ≥ 3) aged more than 16 years who were in work at the time of the accident, reported whether they had returned to work in the 3 years following the accident...
July 17, 2017: Accident; Analysis and Prevention
https://www.readbyqxmd.com/read/28726440/ptsd-symptoms-predict-outcome-in-trauma-informed-treatment-of-intimate-partner-aggression
#5
Suzannah K Creech, Alexandra Macdonald, Justin K Benzer, Gina M Poole, Christopher M Murphy, Casey T Taft
OBJECTIVE: This study sought to extend findings from a randomized controlled trial of the Strength at Home Men's Program (SAH-M) for intimate partner aggression (IPA) in military veterans by examining the impact of pretreatment posttraumatic stress disorder (PTSD) symptoms on treatment efficacy, and by examining new data on postintervention follow-up for individuals who received SAH-M after completing the enhanced treatment as usual (ETAU) wait-list control condition. METHOD: Using data from 125 male veterans who attended the SAH-M program immediately after an intake assessment or after waiting 6-month in the ETAU condition, this study used generalized linear modeling to examine predictors of physical and psychological IPA over a 9-month period of time...
July 20, 2017: Journal of Consulting and Clinical Psychology
https://www.readbyqxmd.com/read/28717512/trauma-related-emotions-and-radical-acceptance-in-dialectical-behavior-therapy-for-posttraumatic-stress-disorder-after-childhood-sexual-abuse
#6
Nora Görg, Kathlen Priebe, Jan R Böhnke, Regina Steil, Anne S Dyer, Nikolaus Kleindienst
BACKGROUND: Posttraumatic Stress Disorder (PTSD) related to childhood sexual abuse (CSA) is often associated with a wide range of trauma-related aversive emotions such as fear, disgust, sadness, shame, guilt, and anger. Intense experience of aversive emotions in particular has been linked to higher psychopathology in trauma survivors. Most established psychosocial treatments aim to reduce avoidance of trauma-related memories and associated emotions. Interventions based on Dialectical Behavior Therapy (DBT) also foster radical acceptance of the traumatic event...
2017: Borderline Personality Disorder and Emotion Dysregulation
https://www.readbyqxmd.com/read/28716937/altered-metabotropic-glutamate-receptor-5-markers-in-ptsd-in-vivo-and-postmortem-evidence
#7
Sophie E Holmes, Matthew J Girgenti, Margaret T Davis, Robert H Pietrzak, Nicole DellaGioia, Nabeel Nabulsi, David Matuskey, Steven Southwick, Ronald S Duman, Richard E Carson, John H Krystal, Irina Esterlis
Posttraumatic stress disorder (PTSD) is a prevalent and highly disabling disorder, but there is currently no targeted pharmacological treatment for it. Dysfunction of the glutamate system has been implicated in trauma and stress psychopathology, resulting in a growing interest in modulation of the glutamate system for the treatment of PTSD. Specifically, the metabotropic glutamate receptor 5 (mGluR5) represents a promising treatment target. We used [(18)F]FPEB, a radioligand that binds to the mGluR5, and positron emission tomography (PET) to quantify in vivo mGluR5 availability in human PTSD vs...
July 17, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28715908/ptsd-psychotherapy-outcome-predicted-by-brain-activation-during-emotional-reactivity-and-regulation
#8
Gregory A Fonzo, Madeleine S Goodkind, Desmond J Oathes, Yevgeniya V Zaiko, Meredith Harvey, Kathy K Peng, M Elizabeth Weiss, Allison L Thompson, Sanno E Zack, Steven E Lindley, Bruce A Arnow, Booil Jo, James J Gross, Barbara O Rothbaum, Amit Etkin
OBJECTIVE: Exposure therapy is an effective treatment for posttraumatic stress disorder (PTSD), but many patients do not respond. Brain functions governing treatment outcome are not well characterized. The authors examined brain systems relevant to emotional reactivity and regulation, constructs that are thought to be central to PTSD and exposure therapy effects, to identify the functional traits of individuals most likely to benefit from treatment. METHOD: Individuals with PTSD underwent functional MRI (fMRI) while completing three tasks assessing emotional reactivity and regulation...
July 18, 2017: American Journal of Psychiatry
https://www.readbyqxmd.com/read/28715907/selective-effects-of-psychotherapy-on-frontopolar-cortical-function-in-ptsd
#9
Gregory A Fonzo, Madeleine S Goodkind, Desmond J Oathes, Yevgeniya V Zaiko, Meredith Harvey, Kathy K Peng, M Elizabeth Weiss, Allison L Thompson, Sanno E Zack, Colleen E Mills-Finnerty, Benjamin M Rosenberg, Raleigh Edelstein, Rachael N Wright, Carena A Kole, Steven E Lindley, Bruce A Arnow, Booil Jo, James J Gross, Barbara O Rothbaum, Amit Etkin
OBJECTIVE: Exposure therapy is an effective treatment for posttraumatic stress disorder (PTSD), but a comprehensive, emotion-focused perspective on how psychotherapy affects brain function is lacking. The authors assessed changes in brain function after prolonged exposure therapy across three emotional reactivity and regulation paradigms. METHOD: Individuals with PTSD underwent functional MRI (fMRI) at rest and while completing three tasks assessing emotional reactivity and regulation...
July 18, 2017: American Journal of Psychiatry
https://www.readbyqxmd.com/read/28714723/the-implementation-and-testing-of-a-referral-management-system-to-address-barriers-to-treatment-seeking-among-primary-care-veterans-with-ptsd
#10
Kyle Possemato, Emily M Johnson, Laura O Wray, Brad Webster, Tracy Stecker
Primary care (PC) patients have low rates of engagement in evidence-based psychotherapy for PTSD due to a variety of patient- and system-level barriers. We conducted a hybrid effectiveness-implementation study of a referral management system, called coordinated and alternative pathway to engagement (CAPE), to address barriers to receiving evidence-based treatment for PTSD. CAPE included the delivery of 1 session of cognitive-behavioral therapy (CBT) within PC to identify and change treatment-seeking beliefs, phone contacts to assist veterans in attending appointments, and PC staff trainings on how to implement clinical practice guidelines for PTSD in PC...
July 17, 2017: Psychological Services
https://www.readbyqxmd.com/read/28713032/psychosocial-rehabilitation-after-war-trauma-with-adaptive-disclosure-design-and-rationale-of-a-comparative-efficacy-trial
#11
Julie D Yeterian, Danielle S Berke, Brett T Litz
BACKGROUND: Posttraumatic stress disorder (PTSD) from warzone exposure is associated with chronic and disabling social and occupational problems. However, functional impairment is rarely assessed or targeted directly in PTSD treatments, which instead focus on symptom reduction. Trauma-related contributors to diminished functioning, including guilt, shame, and anger resulting from morally compromising or loss-based war experiences, are also underemphasized. The goal of this clinical trial is to fill a substantial gap in the treatment of military-related PTSD by testing a modified Adaptive Disclosure (AD) therapy for war-related PTSD stemming from moral injury and traumatic loss focused on improving psychosocial functioning AD...
July 14, 2017: Contemporary Clinical Trials
https://www.readbyqxmd.com/read/28712041/nightmares-in-the-general-population-identifying-potential-causal-factors
#12
Stephanie Rek, Bryony Sheaves, Daniel Freeman
BACKGROUND: Nightmares are inherently distressing, prevent restorative sleep, and are associated with a number of psychiatric problems, but have rarely been the subject of empirical study. Negative affect, linked to stressful events, is generally considered the key trigger of nightmares; hence nightmares have most often been considered in the context of post-traumatic stress disorder (PTSD). However, many individuals with heightened negative affect do not have nightmares. The objective of this study was to identify mechanistically plausible factors, beyond negative affect, that may explain why individuals experience nightmares...
July 15, 2017: Social Psychiatry and Psychiatric Epidemiology
https://www.readbyqxmd.com/read/28711797/symptom-severity-and-disability-in-psychiatric-disorders-the-u-s-collaborative-psychiatric-epidemiology-survey
#13
R García-Velázquez, M Jokela, T H Rosenström
BACKGROUND: While most psychiatric diagnoses are based on simple counts of symptoms, some symptoms may be sign of a more severe mental syndrome than others. This calls for validated estimates of the relative severity specific symptoms imply within a disorder. We focused on four diagnostic disorders: Manic Episode (ME), Major Depressive Episode (MDE), Post-traumatic Stress Disorder (PTSD) and Generalized Anxiety Disorder (GAD). Symptom-specific severity parameters were estimated, and validated by examining their association with levels of self-reported disability in daily activities over and above the number of symptoms...
July 8, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28711610/night-eating-among-veterans-with-obesity
#14
Lindsey M Dorflinger, Christopher B Ruser, Robin M Masheb
The obesity rate is higher among veterans than the general population, yet few studies have examined their eating behaviors, and none have examined the presence of night eating and related comorbidities. This study examines night eating syndrome (NES) among veterans seeking weight management treatment, and relationships between NES and weight, insomnia, disordered eating, and psychological variables. The sample consisted of 110 veterans referred to a weight management program at VA Connecticut Healthcare System...
July 12, 2017: Appetite
https://www.readbyqxmd.com/read/28708415/assessing-the-effectiveness-of-yoga-as-a-complementary-and-alternative-treatment-for-post-traumatic-stress-disorder-a-review-and-synthesis
#15
Nicole A Sciarrino, Christian DeLucia, Kaitlin O'Brien, Kristen McAdams
OBJECTIVES: Posttraumatic stress disorder (PTSD) is a debilitating condition that affects many who have experienced trauma. In addition to skills-focused treatments, exposure-based treatments, cognitive therapy, combination treatments, and EMDR, a number of alternative treatments for PTSD have emerged in recent years. The search for alternative treatments is justified based on the empirical observation that a large percentage of individuals fail to benefit optimally from existing treatments (e...
July 14, 2017: Journal of Alternative and Complementary Medicine: Research on Paradigm, Practice, and Policy
https://www.readbyqxmd.com/read/28703951/secondary-prevention-of-chronic-ptsd-by-early-and-short-term-administration-of-escitalopram-a-prospective-randomized-placebo-controlled-double-blind-trial
#16
Joseph Zohar, Leah Fostick, Alzabeta Juven-Wetzler, Zeev Kaplan, Hadar Shalev, Gavriel Schreiber, Natalie Miroshnik, Arieh Y Shalev, Dan J Stein, Soraya Seedat, Sharain Suliman, Ehud Klein
OBJECTIVE: Prospective studies have not identified a viable pharmacologic strategy for secondary prevention of posttraumatic stress disorder (PTSD). The authors examined whether preventive intervention via early and short-term administration of a selective serotonin reuptake inhibitor (SSRI), within 1 month of exposure to a traumatic event (before diagnosis of PTSD could be made), may reduce the severity of PTSD symptoms according to DSM-IV at 13 months' follow-up. METHODS: Over 25,000 screening calls to patients referred to an emergency department for a traumatic event performed between June 2006 and December 2008 yielded 353 participants who were recruited within the month following a traumatic event ...
July 11, 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/28701969/feasibility-and-efficacy-of-prolonged-exposure-for-ptsd-among-individuals-with-a-psychotic-spectrum-disorder
#17
Anouk L Grubaugh, Kimberly Veronee, Charles Ellis, Wilson Brown, Rebecca G Knapp
Objective: Few empirical studies have examined the feasibility of trauma-focused treatment among individuals with schizophrenia. This lack of research is important given the substantial overlap of trauma exposure and subsequent PTSD with psychotic spectrum disorders, and the potential for PTSD to complicate the course and prognosis of schizophrenia and other variants of severe mental illness. Method: As part of a larger study, 14 veterans with a psychotic spectrum disorder were enrolled to receive prolonged exposure (PE) for PTSD within a single arm open trial study design...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28699778/neurofeedback-as-an-adjunct-therapy-for-treatment-of-chronic-post-traumatic-stress-disorder-related-to-refugee-trauma-and-torture-experiences-two-case-studies
#18
Mirjana Askovic, Anna J Watters, Jorge Aroche, Anthony W F Harris
OBJECTIVE: The objective of this study was to describe the use of neurofeedback for refugee-related chronic post-traumatic stress disorder (PTSD) in two case studies. METHODS: We describe the assessment and application of neurofeedback integrated into the treatment of two clients with chronic PTSD. We include details of our treatment schedule, symptoms and quantitative electrophysiological data for each case. Results All clients achieved significant reduction in symptoms of PTSD and improvement in daily functioning post-neurofeedback therapy...
July 1, 2017: Australasian Psychiatry: Bulletin of Royal Australian and New Zealand College of Psychiatrists
https://www.readbyqxmd.com/read/28699663/posttraumatic-stress-symptoms-and-alcohol-related-outcomes-among-municipal-firefighters
#19
Joe Tomaka, Dejan Magoc, Stormy M Morales-Monks, Anabel C Reyes
This study examined levels of posttraumatic stress symptoms (PTSS) and relationships between PTSS and alcohol-related outcomes in a near census of municipal firefighters. The study also assessed substance-use coping and drinking to cope as potential mediators of such outcomes. Firefighters (N = 740) completed measures that assessed PTSS, alcohol risk behaviors, alcohol problems, drinking motives, and coping with stress. Results showed that 32.4% of firefighters reported significant levels of PTSS using National Center for PTSD (2014) screening cutoff scores...
July 12, 2017: Journal of Traumatic Stress
https://www.readbyqxmd.com/read/28699083/a-therapy-system-for-post-traumatic-stress-disorder-using-a-virtual-agent-and-virtual-storytelling-to-reconstruct-traumatic-memories
#20
Myrthe L Tielman, Mark A Neerincx, Rafael Bidarra, Ben Kybartas, Willem-Paul Brinkman
Although post-traumatic stress disorder (PTSD) is well treatable, many people do not get the desired treatment due to barriers to care (such as stigma and cost). This paper presents a system that bridges this gap by enabling patients to follow therapy at home. A therapist is only involved remotely, to monitor progress and serve as a safety net. With this system, patients can recollect their memories in a digital diary and recreate them in a 3D WorldBuilder. Throughout the therapy, a virtual agent is present to inform and guide patients through the sessions, employing an ontology-based question module for recollecting traumatic memories to further elicit a detailed memory recollection...
August 2017: Journal of Medical Systems
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