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https://www.readbyqxmd.com/read/28926486/comorbid-posttraumatic-stress-disorder-and-traumatic-brain-injury-generalization-of-prolonged-exposure-ptsd-treatment-outcomes-to-postconcussive-symptoms-cognition-and-self-efficacy-in-veterans-and-active-duty-service-members
#1
Gregory K Wolf, Gregory J Mauntel, Tracy Kretzmer, Eric Crawford, Christina Thors, Thad Q Strom, Rodney D Vanderploeg
OBJECTIVES: To examine (a) generalization of the effectiveness of prolonged exposure (PE) therapy for posttraumatic stress disorder (PTSD) in improving postconcussive symptoms (PCSs) and other outcomes in military service members and Veterans (VA) with histories of mild to severe traumatic brain injury (TBI), and (b) factors associated with PCS reduction. SETTING: VA polytrauma medical center. PARTICIPANTS: Consecutive referrals for PTSD treatment of Active Duty (n = 17) or Veterans (n = 27) diagnosed with PTSD and TBI (N = 44)...
September 18, 2017: Journal of Head Trauma Rehabilitation
https://www.readbyqxmd.com/read/28925016/wall-object-punching-an-important-but-under-recognized-form-of-nonsuicidal-self-injury
#2
Nathan A Kimbrel, Shaun P Thomas, Terrell A Hicks, Michael A Hertzberg, Carolina P Clancy, Eric B Elbogen, Eric C Meyer, Bryann B DeBeer, Georgina M Gross, Paul J Silvia, Sandra B Morissette, Kim L Gratz, Patrick S Calhoun, Jean C Beckham
The present research investigated wall/object punching as a form of nonsuicidal self-injury (NSSI) among 1,143 veterans seeking treatment for posttraumatic stress disorder (PTSD). Wall/object punching was remarkably common in this sample (43%), and its inclusion in the definition of NSSI increased estimated prevalence of recent NSSI by 14%. As expected, wall/object punching was strongly associated with other traditional forms of NSSI, post-NSSI relief, and suicide ideation. Male veterans and veterans with PTSD were significantly more likely to engage in wall/object punching than female veterans and veterans without PTSD...
September 19, 2017: Suicide & Life-threatening Behavior
https://www.readbyqxmd.com/read/28917088/depression-anxiety-ptsd-and-comorbidity-in-perinatal-women-in-turkey-a-longitudinal-population-based-study
#3
Pelin Dikmen-Yildiz, Susan Ayers, Louise Phillips
OBJECTIVE: (a) to assess prevalence of depression, anxiety and post-traumatic stress disorder (PTSD) and their comorbidity among women during the perinatal period (b) to examine course of those disorders from pregnancy to 6 months postpartum (c) to determine the rates of new-onset cases at 4-6 weeks and 6 months postpartum. DESIGN: A longitudinal population-based study in which participants completed psychosocial measures of depression, anxiety and PTSD in pregnancy (n = 950), 4-6 weeks (n = 858) and 6 months (n = 829) after birth...
September 6, 2017: Midwifery
https://www.readbyqxmd.com/read/28912423/the-chinese-herbal-formula-free-and-easy-wanderer-ameliorates-oxidative-stress-through-keap1-nrf2-ho-1-pathway
#4
Chunlan Hong, Jingming Cao, Ching-Fen Wu, Onat Kadioglu, Anja Schüffler, Ulrich Kauhl, Sabine M Klauck, Till Opatz, Eckhard Thines, Norbert W Paul, Thomas Efferth
Posttraumatic stress disorder (PTSD) gains a lot of attention due to high prevalence and strong psychological upset, but the etiology remains undefined and effective treatment is quite limited. Growing studies demonstrated the involvement of oxidative stress in various psychiatry diseases, suggesting anti-oxidation therapy might be a strategy for PTSD treatment. Free and Easy Wanderer (FAEW) is a poly-herbal drug clinically used in China for hundreds of years in the treatment of psychiatric disorder. We hypothesized that FAEW exerts clinical effects through the activity against oxidative stress with fluoxetine as antidepressant control drug...
September 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28903795/rapid-triage-of-mental-health-risk-in-emergency-medical-workers-findings-from-typhoon-haiyan
#5
Lauren Sylwanowicz, Merritt Schreiber, Craig Anderson, Carlos Primero D Gundran, Emelie Santamaria, Jaifred Christian F Lopez
OBJECTIVE: To determine the ability of a novel responder mental health self-triage system to predict post-traumatic stress disorder (PTSD) in emergency medical responders after a disaster. METHODS: Participants in this study responded to Typhoon Haiyan, which struck the Philippines in November 2013. They completed the Psychological Simple Triage and Rapid Treatment (PsySTART) responder triage tool, the PTSD Checklist (PCL-5) and the Patient Health Questionnaire-8 (PHQ-8) shortly after responding to this disaster...
September 14, 2017: Disaster Medicine and Public Health Preparedness
https://www.readbyqxmd.com/read/28900387/social-isolation-in-early-versus-late-adolescent-mice-is-associated-with-persistent-behavioral-deficits-that-can-be-improved-by-neurosteroid-based-treatment
#6
Andrea Locci, Philippe Geoffroy, Michel Miesch, Ayikoe-Guy Mensah-Nyagan, Graziano Pinna
Early trauma and stress exposure during a critical period of life may increase the risk of major depressive disorder (MDD) and post-traumatic stress disorder (PTSD) in adulthood. The first-choice treatment for MDD and PTSD are selective serotonin reuptake inhibitor (SSRI) antidepressants. Unfortunately, half of MDD and PTSD patients show resistance to the therapeutic effects of these drugs and more efficient treatments are essential. Both MDD and PTSD patients present reduced levels of allopregnanolone (Allo), a potent endogenous positive allosteric modulator of GABA action at GABAA receptors which are normalized by SSRIs in treatment responders...
2017: Frontiers in Cellular Neuroscience
https://www.readbyqxmd.com/read/28893336/problematic-internet-use-in-gamblers-impact-on-clinical-and-cognitive-measures
#7
Samuel R Chamberlain, Sarah A Redden, Eric Leppink, Jon E Grant
OBJECTIVE: Gambling is a commonplace phenomenon, existing along a continuum from occasional gambling to functionally impairing gambling disorder. The internet may act as a conduit for some gambling behaviors. The impact of problematic internet use on clinical and cognitive features relevant to gambling has received little research attention. METHODS: A total of 206 adults aged 18-30 years who gamble at least five times per year were recruited from the general community and undertook detailed clinical and cognitive assessments...
September 12, 2017: CNS Spectrums
https://www.readbyqxmd.com/read/28893331/diminished-medial-prefrontal-cortex-activation-during-the-recollection-of-stressful-events-is-an-acquired-characteristic-of-ptsd
#8
M K Dahlgren, L M Laifer, M B VanElzakker, R Offringa, K C Hughes, L K Staples-Bradley, S J Dubois, N B Lasko, C A Hinojosa, S P Orr, R K Pitman, L M Shin
BACKGROUND: Previous research has shown relatively diminished medial prefrontal cortex activation and heightened psychophysiological responses during the recollection of personal events in post-traumatic stress disorder (PTSD), but the origin of these abnormalities is unknown. Twin studies provide the opportunity to determine whether such abnormalities reflect familial vulnerabilities, result from trauma exposure, or are acquired characteristics of PTSD. METHODS: In this case-control twin study, 26 male identical twin pairs (12 PTSD; 14 non-PTSD) discordant for PTSD and combat exposure recalled and imagined trauma-unrelated stressful and neutral life events using a standard script-driven imagery paradigm during functional magnetic resonance imaging and concurrent skin conductance measurement...
September 12, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28892066/effects-of-vagus-nerve-stimulation-on-extinction-of-conditioned-fear-and-post-traumatic-stress-disorder-symptoms-in-rats
#9
L J Noble, I J Gonzalez, V B Meruva, K A Callahan, B D Belfort, K R Ramanathan, E Meyers, M P Kilgard, R L Rennaker, C K McIntyre
Exposure-based therapies help patients with post-traumatic stress disorder (PTSD) to extinguish conditioned fear of trauma reminders. However, controlled laboratory studies indicate that PTSD patients do not extinguish conditioned fear as well as healthy controls, and exposure therapy has high failure and dropout rates. The present study examined whether vagus nerve stimulation (VNS) augments extinction of conditioned fear and attenuates PTSD-like symptoms in an animal model of PTSD. To model PTSD, rats were subjected to a single prolonged stress (SPS) protocol, which consisted of restraint, forced swim, loss of consciousness, and 1 week of social isolation...
August 22, 2017: Translational Psychiatry
https://www.readbyqxmd.com/read/28891785/attachment-style-moderates-effects-of-fkbp5-polymorphisms-and-childhood-abuse-on-posttraumatic-stress-symptoms-results-from-the-national-health-and-resilience-in-veterans-study
#10
Amanda J F Tamman, Lauren M Sippel, Shizhong Han, Yuval Neria, John H Krystal, Steven M Southwick, Joel Gelernter, Robert H Pietrzak
OBJECTIVES: To determine the main and interactive effects of four FKBP5 polymorphisms (rs9296158, rs3800373, rs1360780, and rs9470080), childhood abuse, and attachment style in predicting severity of PTSD symptoms in two independent, nationally representative samples of U.S. military veterans. METHODS: Data were analyzed from two independent samples of European American (EA) U.S. military veterans who participated in the National Health and Resilience in Veterans Study (N = 1,585 and 577 respectively)...
September 11, 2017: World Journal of Biological Psychiatry
https://www.readbyqxmd.com/read/28890702/a-pilot-study-of-the-effects-of-mindfulness-based-stress-reduction-on-post-traumatic-stress-disorder-symptoms-and-brain-response-to-traumatic-reminders-of-combat-in-operation-enduring-freedom-operation-iraqi-freedom-combat-veterans-with-post-traumatic-stress
#11
James Douglas Bremner, Sanskriti Mishra, Carolina Campanella, Majid Shah, Nicole Kasher, Sarah Evans, Negar Fani, Amit Jasvant Shah, Collin Reiff, Lori L Davis, Viola Vaccarino, James Carmody
OBJECTIVE: Brain imaging studies in patients with post-traumatic stress disorder (PTSD) have implicated a circuitry of brain regions including the medial prefrontal cortex, amygdala, hippocampus, parietal cortex, and insula. Pharmacological treatment studies have shown a reversal of medial prefrontal deficits in response to traumatic reminders. Mindfulness-based stress reduction (MBSR) is a promising non-pharmacologic approach to the treatment of anxiety and pain disorders. The purpose of this study was to assess the effects of MBSR on PTSD symptoms and brain response to traumatic reminders measured with positron-emission tomography (PET) in Operation Enduring Freedom/Operation Iraqi Freedom (OEF/OIF) combat veterans with PTSD...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/28888982/disrupting-nnos-psd-95-coupling-in-the-hippocampal-dentate-gyrus-promotes-extinction-memory-retrieval
#12
Jun Li, Zhou Han, Bo Cao, Cheng-Yun Cai, Yu-Hui Lin, Fei Li, Hai-Ying Wu, Lei Chang, Chun-Xia Luo, Dong-Ya Zhu
Granule cells in the dentate gyrus regenerate constantly in adult hippocampus and then integrate into neural circuits in the hippocampus thereby providing the neural basis for learning and memory. Promoting the neurogenesis in the hippocampus facilitates learning and memory such as spatial learning, object identification, and extinction learning. The interaction between neuronal nitric oxide synthase (nNOS) and postsynaptic density protein-95 (PSD-95) is reported to negatively regulate neurogenesis in brain, so we hypothesized that disrupting this interaction might facilitate the neurogenesis in the dentate gyrus (DG) and thus enhance the extinction memory retrieval of fear learning...
September 6, 2017: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/28886591/predictors-of-early-dropout-in-treatment-for-gambling-disorder-the-role-of-personality-disorders-and-clinical-syndromes
#13
G Maniaci, C La Cascia, F Picone, A Lipari, C Cannizzaro, D La Barbera
Several treatment options for gambling disorder (GD) have been tested in recent years; however dropout levels still remain high. This study aims to evaluate whether the presence of psychiatric comorbidities predicts treatment outcome according to Millon's evolutionary theory, following a six-month therapy for GD. The role of severity, duration of the disorder, typology of gambling (mainly online or offline) and pharmacological treatment were also analysed. The recruitment included 194 pathological gamblers (PGs) to be compared with 78 healthy controls (HCs)...
August 5, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28886114/delivery-of-mental-health-treatment-to-combat-veterans-with-psychiatric-diagnoses-and-tbi-histories
#14
Shannon R Miles, Juliette M Harik, Natalie E Hundt, Joseph Mignogna, Nicholas J Pastorek, Karin E Thompson, Jessica S Freshour, Hong J Yu, Jeffrey A Cully
Traumatic brain injury (TBI) and mental health (MH) disorders are prevalent in combat veterans returning from Afghanistan and/or Iraq (hereafter referred to as returning veterans). Accurate estimates of service utilization for veterans with and without TBI exposure (referred to as TBI history) are imperative in order to provide high quality healthcare to returning veterans. We examined associations between TBI history and MH service utilization in a subsample of returning veterans who were newly diagnosed with posttraumatic stress disorder (PTSD), depression, and/or anxiety in the 2010 fiscal year (N = 55,458)...
2017: PloS One
https://www.readbyqxmd.com/read/28885946/the-association-between-service-members-participation-in-humanitarian-aid-and-disaster-relief-and-mental-health-symptoms-and-treatments
#15
Yeong Kim, Nilam Patel, Glen Diehl, Patrick Richard
INTRODUCTION: There is a scarcity of research establishing a relationship between mental illness and the U.S. military service members who participate in the field of military humanitarian assistance/disaster relief (HA/DR). One of the few studies in this area showed that participation in military HA/DR was not associated with depressive symptoms, however, the study was limited by sample size. This study examined (1) the relationship between participation in military HA/DR and mental health symptoms and military stress and (2) the relationship between HA/DR and mental health treatment and therapy...
September 2017: Military Medicine
https://www.readbyqxmd.com/read/28885931/impact-of-engagement-in-exercise-on-sleep-quality-among-veterans-with-posttraumatic-stress-disorder-symptoms
#16
Jeane Bosch, Terri L Weaver, Thomas C Neylan, Ellen Herbst, Shannon E McCaslin
BACKGROUND: Exercise has beneficial effects for physical health outcomes and has also been shown to reduce the severity of psychological health symptoms. Recent studies have shown a potentially positive impact of exercise on posttraumatic stress disorder (PTSD). Prominent among those with PTSD, sleep disturbance and nightmares are among the top three PTSD symptoms commonly reported by treatment-seeking Veterans. Regular physical exercise has been consistently associated with better sleep...
September 2017: Military Medicine
https://www.readbyqxmd.com/read/28885864/examining-trauma-and-readiness-to-change-among-women-in-a-community-re-entry-program
#17
Michael Killian, Andrea N Cimino, Natasha S Mendoza, Randy Shively, Kami Kunz
BACKGROUND: Posttraumatic stress disorder (PTSD) and co-occurring substance use disorders (SUDs) are common among women who are incarcerated. OBJECTIVE: The purpose of this study was to examine the relationship between trauma and readiness to change substance use behaviors. METHODS: This study used data from 103 participants enrolled in a residential re-entry program for women with SUDs and trauma history. Women reporting clinically elevated Trauma Symptom Inventory (TSI) subscale scores were compared to those without elevated scores on the University of Rhode Island Change Assessment (URICA) readiness to change instrument...
September 8, 2017: Substance Use & Misuse
https://www.readbyqxmd.com/read/28880607/mind-body-therapy-for-military-veterans-with-post-traumatic-stress-disorder-a-systematic-review
#18
Robin E Cushing, Kathryn L Braun
OBJECTIVE: About a third of service members returning from post-9/11 deployment in Afghanistan and Iraq report combat-related mental health conditions, but many do not seek conventional treatment. Mind-body therapies have been offered as alternative approaches to decreasing post-traumatic stress disorder (PTSD), but no review of studies with veterans of post-9/11 operations was found. The objective of this study was to fill that gap. DESIGN: A systematic literature review was conducted following the preferred items for systematic reviews and meta-analyses (PRISMA) guidelines...
September 7, 2017: Journal of Alternative and Complementary Medicine: Research on Paradigm, Practice, and Policy
https://www.readbyqxmd.com/read/28878718/errors-in-the-2017-apa-clinical-practice-guideline-for-the-treatment-of-ptsd-what-the-data-actually-says
#19
REVIEW
Sarah K Dominguez, Christopher W Lee
The American Psychological Association (APA) Practice Guidelines for the Treatment of Posttraumatic Stress Disorder (PTSD) concluded that there was strong evidence for cognitive behavioral therapy (CBT), cognitive processing therapy (CPT), cognitive therapy (CT), and exposure therapy yet weak evidence for eye movement desensitization and reprocessing (EMDR). This is despite the findings from an associated systematic review which concluded that EMDR leads to loss of PTSD diagnosis and symptom reduction. Depression symptoms were also found to improve more with EMDR than control conditions...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28878711/parental-factors-associated-with-child-post-traumatic-stress-following-injury-a-consideration-of-intervention-targets
#20
REVIEW
Anna E Wise, Douglas L Delahanty
Post-traumatic stress disorder (PTSD) symptoms are relatively common following pediatric traumatic injury and are related to poor long-term child outcomes. However, due to concerns regarding the efficacy of early child preventive interventions, and difficulty intervening with injured and medicated children soon after the event, it is not feasible to provide early psychological interventions to children exposed to traumatic injury. Parental PTSD symptoms and reactions to the child's traumatic injury impact child outcomes and provide potential targets for early intervention to reduce child symptom development without involving the child...
2017: Frontiers in Psychology
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