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Spatio-temporal modeling

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https://www.readbyqxmd.com/read/28738263/prenatal-exposure-to-pm2-5-and-birth-weight-a-pooled-analysis-from-three-north-american-longitudinal-pregnancy-cohort-studies
#1
Maria José Rosa, Ashley Pajak, Allan C Just, Perry E Sheffield, Itai Kloog, Joel Schwartz, Brent Coull, Michelle Bosquet Enlow, Andrea A Baccarelli, Kathi Huddleston, John E Niederhuber, Martha María Téllez Rojo, Robert O Wright, Chris Gennings, Rosalind J Wright
A common practice when analyzing multi-site epidemiological data is to include a term for 'site' to account for unmeasured effects at each location. This practice should be carefully considered when site can have complex relationships with important demographic and exposure variables. We leverage data from three longitudinal North American pregnancy cohorts to demonstrate a novel method to assess study heterogeneity and potential combinability of studies for pooled analyses in order to better understand how to consider site in analyses...
July 21, 2017: Environment International
https://www.readbyqxmd.com/read/28738085/a-bayesian-spatio-temporal-model-for-forecasting-anaplasma-species-seroprevalence-in-domestic-dogs-within-the-contiguous-united-states
#2
Yan Liu, Stella C Watson, Jenna R Gettings, Robert B Lund, Shila K Nordone, Michael J Yabsley, Christopher S McMahan
This paper forecasts the 2016 canine Anaplasma spp. seroprevalence in the United States from eight climate, geographic and societal factors. The forecast's construction and an assessment of its performance are described. The forecast is based on a spatial-temporal conditional autoregressive model fitted to over 11 million Anaplasma spp. seroprevalence test results for dogs conducted in the 48 contiguous United States during 2011-2015. The forecast uses county-level data on eight predictive factors, including annual temperature, precipitation, relative humidity, county elevation, forestation coverage, surface water coverage, population density and median household income...
2017: PloS One
https://www.readbyqxmd.com/read/28736751/quantifying-time-varying-cellular-secretions-with-local-linear-models
#3
Jeff M Byers, Joseph A Christodoulides, James B Delehanty, Deepa Raghu, Marc P Raphael
Extracellular protein concentrations and gradients initiate a wide range of cellular responses, such as cell motility, growth, proliferation and death. Understanding inter-cellular communication requires spatio-temporal knowledge of these secreted factors and their causal relationship with cell phenotype. Techniques which can detect cellular secretions in real time are becoming more common but generalizable data analysis methodologies which can quantify concentration from these measurements are still lacking...
July 2017: Heliyon
https://www.readbyqxmd.com/read/28736652/statistical-properties-of-dynamic-speckles-from-flowing-brownian-scatterers-in-the-vicinity-of-the-image-plane-in-optical-coherence-tomography
#4
Ivan Popov, Andrew Weatherbee, I Alex Vitkin
A closed-form analytical expression is obtained for the spatio-temporal correlation function of the scattered radiation detected in fiber-based optical coherence tomography (OCT), assuming a clean optical system arrangement in the OCT sample arm. It is shown that the transverse flow component causes purely translational speckle motion with the predicted speckle velocity 2x higher than the velocity of the flowing particles as would be observed in the image plane under incoherent illumination. It is also shown that both speckle velocity and speckle radius do not depend on the position of the scattering volume relative to the focal plane, hence the derived correlation function is independent of the position of the scattering volume relative to the focal plane...
April 1, 2017: Biomedical Optics Express
https://www.readbyqxmd.com/read/28733770/distinct-and-flexible-rates-of-online-control
#5
John de Grosbois, Luc Tremblay
Elliott et al. (Hum Mov Sci 10:393-418, 1991) proposed a pseudocontinuous model of online control whereby overlapping corrections lead to the appearance of smooth kinematic profiles in the presence of online feedback. More recently, it was also proposed that online control is not a singular process [see Elliott et al. (Psychol Bull 136(6):1023-1044, 2010)]. However, support for contemporary models of online control were based on methodologies that were not designed to be sensitive to different online control sub-processes...
July 21, 2017: Psychological Research
https://www.readbyqxmd.com/read/28729711/an-ecological-and-digital-epidemiology-analysis-on-the-role-of-human-behavior-on-the-2014-chikungunya-outbreak-in-martinique
#6
Benjamin Roche, Béatrice Gaillard, Lucas Léger, Renélise Pélagie-Moutenda, Thomas Sochacki, Bernard Cazelles, Martine Ledrans, Alain Blateau, Didier Fontenille, Manuel Etienne, Frédéric Simard, Marcel Salathé, André Yébakima
Understanding the spatio-temporal dynamics of endemic infections is of critical importance for a deeper understanding of pathogen transmission, and for the design of more efficient public health strategies. However, very few studies in this domain have focused on emerging infections, generating a gap of knowledge that hampers epidemiological response planning. Here, we analyze the case of a Chikungunya outbreak that occurred in Martinique in 2014. Using time series estimates from a network of sentinel practitioners covering the entire island, we first analyze the spatio-temporal dynamics and show that the largest city has served as the epicenter of this epidemic...
July 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28725435/biogeophysical-and-physiological-processes-drive-movement-patterns-in-a-marine-predator
#7
Lucy A Howey, Bradley M Wetherbee, Emily R Tolentino, Mahmood S Shivji
BACKGROUND: Blue sharks (Prionace glauca) are among the most abundant and widely distributed of oceanic elasmobranchs. Millions are taken annually in pelagic longline fisheries and comprise the highest component of auctioned fin weight in the international shark fin trade. Though studies of blue sharks outnumber those of other large pelagic sharks, the species' complicated and sexually segregated life history still confound current understanding of Atlantic movement patterns. Lack of detailed information regarding movement and vertical behavior continues to limit management efforts that require such data for stock assessment and sustainable catch modeling...
2017: Movement Ecology
https://www.readbyqxmd.com/read/28720886/spatio-temporal-variations-of-typhoid-and-paratyphoid-fevers-in-zhejiang-province-china-from-2005-to-2015
#8
Hua Gu, Wenjie Fan, Kui Liu, Shuwen Qin, Xiuyang Li, Jianmin Jiang, Enfu Chen, Yibiao Zhou, Qingwu Jiang
Typhoid and paratyphoid are two common enteric infectious diseases with serious gastrointestinal symptoms. Data was collected of the registered cases in Zhejiang Province from 2005 to 2015. The epidemiological characteristics were investigated and high-risk regions were detected with descriptive epidemiological methods and in-depth spatio-temporal statistics. A sharp decline in the incidences of both diseases was observed. The seasonal patterns were identified with typhoid and paratyphoid, one in summer from May to September was observed from 2005 to 2010 and the other lesser one in spring from January to March only observed from 2005 to 2007...
July 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28716208/spatial-dynamics-of-porcine-epidemic-diarrhea-ped-spread-in-the-southern-kyushu-japan
#9
Yosuke Sasaki, Haruya Toyomaki, Satoshi Sekiguchi, Masuo Sueyoshi, Kohei Makita, Satoshi Otake, Andres Perez, Julio Alvarez
Porcine epidemic diarrhea (PED) was detected for the first time in seven years in Japan in October 2013 in Okinawa Prefecture. By December 2013, PED had spread into Miyazaki and Kagoshima Prefectures in the southern part of Kyushu, one of the regions with the highest farm density in the country. The objective of the study here was to assess the spatial dynamics of PED spread during the 8 months of the epidemic in the southern part of Kyushu between December 2013, the month observed first case in the studied region, and July 2014...
September 1, 2017: Preventive Veterinary Medicine
https://www.readbyqxmd.com/read/28715936/selection-of-gait-parameters-for-differential-diagnostics-of-patients-with-de-novo-parkinson-s-disease
#10
Milica Djurić-Jovičić, Minja Belić, Iva Stanković, Saša Radovanović, Vladimir S Kostić
BACKGROUND: Gait disturbances are an integral part of clinical manifestations of Parkinson's disease (PD), even in the initial stages of the disease. Our goal was to identify the set of spatio-temporal gait parameters that bear the highest relevance for characterizing de novo PD patients. METHODS: Forty patients with de novo PD and forty healthy controls were recorded while walking over an electronic walkway in three different conditions: (1) base walking, (2) walking with an additional motor task, (3) walking with an additional mental task...
July 17, 2017: Neurological Research
https://www.readbyqxmd.com/read/28714698/microrna-intercellular-transfer-and-bioelectrical-regulation-of-model-multicellular-ensembles-by-the-gap-junction-connectivity
#11
Javier Cervera, Salvador Meseguer, Salvador Mafe
We have studied theoretically the microRNA (miRNA) intercellular transfer through voltage-gated gap junctions in terms of a biophysically-grounded system of coupled differential equations. Instead of modeling a specific system, we use a general approach describing the interplay between the genetic mechanisms and the single-cell electric potentials. The dynamics of the multicellular ensemble are simulated under different conditions including spatially-inhomogeneous transcription rates and local intercellular transfer of miRNAs...
July 17, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/28713200/spatio-temporal-precipitation-climatology-over-complex-terrain-using-a-censored-additive-regression-model
#12
Reto Stauffer, Georg J Mayr, Jakob W Messner, Nikolaus Umlauf, Achim Zeileis
Flexible spatio-temporal models are widely used to create reliable and accurate estimates for precipitation climatologies. Most models are based on square root transformed monthly or annual means, where a normal distribution seems to be appropriate. This assumption becomes invalid on a daily time scale as the observations involve large fractions of zero observations and are limited to non-negative values. We develop a novel spatio-temporal model to estimate the full climatological distribution of precipitation on a daily time scale over complex terrain using a left-censored normal distribution...
June 15, 2017: International Journal of Climatology: a Journal of the Royal Meteorological Society
https://www.readbyqxmd.com/read/28712959/associations-between-long-term-exposure-to-air-pollution-glycosylated-hemoglobin-and-diabetes
#13
Trenton Honda, Vivian C Pun, Justin Manjourides, Helen Suh
BACKGROUND: Air pollution exposures have been shown to adversely impact health through a number of biological pathways associated with glucose metabolism. However, few studies have evaluated the associations between air pollution and glycosylated hemoglobin (HbA1c) levels. Further, no studies have evaluated these associations in US populations or investigated whether associations differ in diabetic as compared to non-diabetic populations. To address this knowledge gap, we investigated the associations between airborne fine particulate matter (PM2...
June 26, 2017: International Journal of Hygiene and Environmental Health
https://www.readbyqxmd.com/read/28707354/additive-neurogenesis-supported-by-multiple-stem-cell-populations-mediates-adult-spinal-cord-development-a-spatio-temporal-statistical-mapping-analysis-in-a-teleost-model-of-indeterminate-growth
#14
Ruxandra F Sîrbulescu, Iulian Ilieş, Annette Meyer, Günther K H Zupanc
The knifefish Apteronotus leptorhynchus exhibits indeterminate growth throughout adulthood. This phenomenon extends to the spinal cord, presumably through the continuous addition of new neurons and glial cells. However, little is known about the developmental dynamics of cells added during adult growth. The present work characterizes the structural and functional development of the adult spinal cord in this model organism through a comprehensive quantitative analysis of the spatial and temporal dynamics of new cells at various developmental stages...
July 13, 2017: Developmental Neurobiology
https://www.readbyqxmd.com/read/28707306/current-reinforcement-model-reproduces-center-in-center-vein-trajectory-of-physarum-polycephalum
#15
Dai Akita, Daniel Schenz, Shigeru Kuroda, Katsuhiko Sato, Kei-Ichi Ueda, Toshiyuki Nakagaki
Vein networks span the whole body of the amoeboid organism in the plasmodial slime mould Physarum polycephalum, and the network topology is rearranged within an hour in response to spatio-temporal variations of the environment. It has been reported that this tube morphogenesis is capable of solving mazes, and a mathematical model, named the 'current reinforcement rule', was proposed based on the adaptability of the veins. Although it is known that this model works well for reproducing some key characters of the organism's maze-solving behaviour, one important issue is still open: In the real organism, the thick veins tend to trace the shortest possible route by cutting the corners at the turn of corridors, following a center-in-center trajectory, but it has not yet been examined whether this feature also appears in the mathematical model, using corridors of finite width...
July 13, 2017: Development, Growth & Differentiation
https://www.readbyqxmd.com/read/28704934/functioning-of-fluorescent-proteins-in-aggregates-in-anthozoa-species-and-in-recombinant-artificial-models
#16
Natalia V Povarova, Natalia D Petri, Anna E Blokhina, Alexey M Bogdanov, Nadya G Gurskaya, Konstantin A Lukyanov
Despite great advances in practical applications of fluorescent proteins (FPs), their natural function is poorly understood. FPs display complex spatio-temporal expression patterns in living Anthozoa coral polyps. Here we applied confocal microscopy, specifically, the fluorescence recovery after photobleaching (FRAP) technique to analyze intracellular localization and mobility of endogenous FPs in live tissues. We observed three distinct types of protein distributions in living tissues. One type of distribution, characteristic for Anemonia, Discosoma and Zoanthus, is free, highly mobile cytoplasmic localization...
July 12, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28704700/environmental-exposure-to-pesticides-and-the-risk-of-parkinson-s-disease-in-the-netherlands
#17
Maartje Brouwer, Anke Huss, Marianne van der Mark, Peter C G Nijssen, Wim M Mulleners, Antonetta M G Sas, Teus van Laar, Geert R de Snoo, Hans Kromhout, Roel C H Vermeulen
BACKGROUND: Exposure to pesticides has been linked to Parkinson's disease (PD), although associations between specific pesticides and PD have not been well studied. Residents of rural areas can be exposed through environmental drift and volatilization of agricultural pesticides. OBJECTIVES: Our aim was to investigate the association between lifetime environmental exposure to individual pesticides and the risk of PD, in a national case-control study. METHODS: Environmental exposure to pesticides was estimated using a spatio-temporal model, based on agricultural crops around the residential address...
July 10, 2017: Environment International
https://www.readbyqxmd.com/read/28704632/measuring-memory-and-attention-to-preview-in-motion
#18
Richard J Jagacinski, Gordon M Hammond, Emanuele Rizzi
Objective Use perceptual-motor responses to perturbations to reveal the spatio-temporal detail of memory for the recent past and attention to preview when participants track a winding roadway. Background Memory of the recently passed roadway can be inferred from feedback control models of the participants' manual movement patterns. Similarly, attention to preview of the upcoming roadway can be inferred from feedforward control models of manual movement patterns. Method Perturbation techniques were used to measure these memory and attention functions...
August 2017: Human Factors
https://www.readbyqxmd.com/read/28704417/bayesian-spatio-temporal-modeling-of-mortality-in-relation-to-malaria-incidence-in-western-kenya
#19
Sammy Khagayi, Nyaguara Amek, Godfrey Bigogo, Frank Odhiambo, Penelope Vounatsou
INTRODUCTION: The effect of malaria exposure on mortality using health facility incidence data as a measure of transmission has not been well investigated. Health and demographic surveillance systems (HDSS) routinely capture data on mortality, interventions and other household related indicators, offering a unique platform for estimating and monitoring the incidence-mortality relationship in space and time. METHODS: Mortality data from the HDSS located in Western Kenya collected from 2007 to 2012 and linked to health facility incidence data were analysed using Bayesian spatio-temporal survival models to investigate the relation between mortality (all-cause/malaria-specific) and malaria incidence across all age groups...
2017: PloS One
https://www.readbyqxmd.com/read/28695959/migration-behavior-of-pgcs-and-asymmetrical-gonad-formation-in-pond-smelt-hypomesus-nipponensis
#20
Eisuke Takahashi, Yu Shimizu, Hirotaro Urushibata, Yutaka Kawakami, Katsutoshi Arai, Etsuro Yamaha
In teleost fish, the gonad originates from primordial germ cells (PGCs) and somatic cells. However, it is not clear whether the final gonadal position is determined by anteroposterior and dextrosinistral differentiation of endodermal organs or by the distribution of PGCs. The pond smelt has a transparent body even after hatching, enabling clear observation of PGC distribution and endodermal differentiation. Here, we first examined normal embryonic development to define the spatio-temporal characteristics of our developmental model...
2017: International Journal of Developmental Biology
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