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https://www.readbyqxmd.com/read/29768114/differences-in-contraceptive-discontinuation-among-black-and-white-women-evidence-from-the-contraceptive-choice-project
#1
Jenifer E Allsworth, Gina M Secura, Olufemi O Ajibade, Jeffrey F Peipert
OBJECTIVE: We sought to evaluate whether differences in rates of contraceptive discontinuation exist among black and white women receiving contraceptive counseling and no-cost contraception among users of long-acting reversible contraceptive (LARC; intrauterine devices or subdermal implant) and non-LARC (oral contraceptive pills, contraceptive vaginal ring, patch, or injection) methods. MATERIALS AND METHODS: We analyzed data from a prospective cohort study of 7546 non-Hispanic black and white women who participated in the Contraceptive CHOICE Project...
May 2018: Journal of Women's Health
https://www.readbyqxmd.com/read/29704897/occurrence-of-anembryonic-pregnancy-with-use-of-levonorgestrel-subdermal-implant-jadelle%C3%A2-a-case-report
#2
Jude Moutchia-Suh, Dave-King Moutourou Mouemba, Calypse Asangbe Ngwasiri
BACKGROUND: Progestin-only subdermal implants are one of the most effective contraceptive methods. Anembryonic pregnancy is not reported as a possible outcome in cases of contraceptive failure of these products. We present a rare case of anembryonic pregnancy occurring in a woman with levonorgestrel-releasing implant (JADELLE®). CASE PRESENTATION: A 31-year-old Cameroonian (black African) housewife with a JADELLE® implant for 13 months, consulted at our hospital for a 1-month history of pelvic pain, prolonged menstrual bleeding, and spotting...
April 29, 2018: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/29702080/continuation-of-long-acting-reversible-contraceptives-among-medicaid-patients
#3
Max J Romano, Patryce Toye, Loral Patchen
OBJECTIVE: Our objective was to compare continuation and complication rates of subdermal etonogestrel implants and intrauterine devices (IUDs) using Medicaid insurance claims. STUDY DESIGN: We performed a retrospective cohort study using insurance claims data for 15- to 44-year-old subjects receiving implants or IUDs from 2012 to 2015 in a Medicaid managed care organization in Washington, DC, and Maryland. We performed a planned Kaplan-Meier survival analysis for long-acting reversible contraceptive (LARC) continuation, defined as the absence of a claim for LARC removal, during periods of continuous insurance plan enrollment...
April 24, 2018: Contraception
https://www.readbyqxmd.com/read/29684326/12-month-discontinuation-rates-of-levonorgestrel-intrauterine-system-13-5mg-and-subdermal-etonogestrel-implant-in-adult-women-a-retrospective-claims-database-analysis
#4
Amy Law, Laura Liao, Jay Lin, Avin Yaldo, Richard Lynen
OBJECTIVE: To investigate the 12-month discontinuation rates of levonorgestrel intrauterine system 13.5mg (LNG-IUS 13.5) and subdermal etonogestrel (ENG) implant in the US. STUDY DESIGN: We identified adult women (18-44years) who had an insertion of LNG-IUS 13.5 or ENG implant from the MarketScan Commercial claims database (7/1/2013-9/30/2014). Women were required to have 12months of continuous insurance coverage prior to the insertion (baseline) and at least 12-months after (follow-up)...
April 20, 2018: Contraception
https://www.readbyqxmd.com/read/29610715/complications-of-subcutaneous-contraception-a-review
#5
REVIEW
Rebecca C Ramdhan, Emily Simonds, Charlotte Wilson, Marios Loukas, Rod J Oskouian, R Shane Tubbs
Over 62 million women in the United States are of childbearing age and 60% of them use contraception. Subcutaneous contraceptives include implantable contraceptives and subcutaneous injections. Implantable contraception involves subdermal time-release of synthetic progestin, which allows for several years of continuous, highly effective contraception. Its main effects are inhibition of ovulation and thickening of the cervical mucus. Many complications have been associated with subcutaneous contraception, including menstrual disturbances, headache, weight gain, acne, dizziness, mood disturbances, nausea, lower abdominal pain, hair loss, loss of libido, pain at the implant site, neuropathy, and follicular cysts...
January 31, 2018: Curēus
https://www.readbyqxmd.com/read/29595351/treatment-and-prevention-of-hiv-infection-with-long-acting-antiretrovirals
#6
Laura Benítez-Gutiérrez, Vicente Soriano, Silvia Requena, Ana Arias, Pablo Barreiro, Carmen de Mendoza
Current antiretroviral therapy allows to achieve and sustain maximal suppression of HIV replication in most treated patients. As result, the life expectancy of HIV-infected persons has improved dramatically and is nowadays similar to that of the HIV-negative population. However, oral antiretrovirals have to be taken daily and indefinitely to avoid resumption of HIV replication and selection of drug resistance. Unfortunately, drug adherence is often suboptimal and tends to decline over time. Areas covered: New drugs, formulations and delivery systems are being developed for extended-release of antiretrovirals...
May 2018: Expert Review of Clinical Pharmacology
https://www.readbyqxmd.com/read/29579732/development-validation-and-utilization-of-a-highly-sensitive-lc-ms-ms-method-for-quantification-of-levonorgestrel-released-from-a-subdermal-implant-in-human-plasma
#7
Lauren R Cirrincione, Sujan Dilly Penchala, Kimberly K Scarsi, Anthony T Podany, Lee C Winchester, David J Back, Saye H Khoo, Courtney V Fletcher, Marco Siccardi, Laura J Else
Levonorgestrel (LNG) is a synthetic progestin that is available in oral contraceptive tablets, a subdermal implant, and an intrauterine system for contraception. LNG pharmacokinetics are a pivotal determinant of contraceptive efficacy and essential in assessing drug-drug interactions influencing LNG exposure following different routes of LNG administration. A highly sensitive LC-MS/MS method was developed and validated to quantify levonorgestrel in human plasma. Liquid-liquid extraction was utilized with a sample volume of 500 μL to extract levonorgestrel from plasma...
March 12, 2018: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/29574095/changes-in-uptake-and-cost-of-long-acting-reversible-contraceptive-devices-following-the-introduction-of-a-new-low-cost-levonorgestrel-iud-in-utah-s-title-x-clinics-a-retrospective-review
#8
Lauryn P Roth, Jessica N Sanders, Rebecca G Simmons, Holly Bullock, Elizabeth Jacobson, David K Turok
OBJECTIVE: To assess changes in long-acting reversible contraceptive (LARC) method uptake at Utah's Title X clinics before and after introduction of a new, low-cost levonorgestrel (LNG) 52mg IUD (Liletta®). STUDY DESIGN: We conducted a retrospective medical record review of LARC visits occurring at seven Title-X family planning clinics in Utah before the introduction of the low-cost LNG IUD (pre-introduction period: 01/01/2014-04/30/2015) and after (post-introduction period: 05/01/2015-03/31/2016)...
March 21, 2018: Contraception
https://www.readbyqxmd.com/read/29553853/influence-of-age-on-tolerability-safety-and-effectiveness-of-subdermal-contraceptive-implants
#9
Esther López Del Cerro, Carolina Serrano Diana, Ana María Castillo Cañadas, Esteban González Mirasol, Francisco García Santos, María Teresa Gómez García, Gaspar González de Merlo
The use of long-acting contraceptive methods is on the rise. The aim of this study was to describe the main variables (effectiveness, tolerability, menstrual bleeding) associated with the use of subdermal contraceptive implants and to investigate the influence of age on these variables. This was a descriptive, retrospective, observational study of 221 cases of contraceptive implants inserted at a Spanish hospital between 2006 and 2015. The mean age of implant users was 31.2 ± 7.5 years. Effectiveness was 100% and good tolerability was recorded for 86...
March 19, 2018: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/29530358/case-report-embolization-of-a-contraceptive-implant-into-the-pulmonary-vasculature-in-an-adolescent-female
#10
Gabriel T Gao, William Binder
Nexplanon is a long-acting 4cm radio-opaque rod shaped contraceptive device implanted in the subdermal layer of the inner, upper arm. Complications from implantation are uncommon and mostly local and minor, including infection at the implantation site with resulting cellulitis or abscess, hematoma, abnormal scar formation, or local damage to nerves and blood vessels. Intravascular insertion is estimated to be at 1.3 per million Nexplanon implants, and migration and embolization is a rare complication of this device...
March 3, 2018: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29522414/psychophysical-evaluation-of-subdermal-electrical-stimulation-in-relation-to-prosthesis-sensory-feedback
#11
Bo Geng, Jian Dong, Winnie Jensen, Strahinja Dosen, Dario Farina, Ernest Nlandu Kamavuako
This paper evaluated the psychophysical properties of subdermal electrical stimulation to investigate its feasibility in providing sensory feedback for limb prostheses. The detection threshold (DT), pain threshold (PT), just noticeable difference (JND), as well as the elicited sensation quality, comfort, intensity, and location were assessed in 16 healthy volunteers during stimulation of the ventral and dorsal forearm with subdermal electrodes. Moreover, the results were compared with those obtained from transcutaneous electrical stimulation...
March 2018: IEEE Transactions on Neural Systems and Rehabilitation Engineering
https://www.readbyqxmd.com/read/29500162/safety-quality-and-acceptability-of-contraceptive-subdermal-implant-provision-by-community-health-extension-workers-versus-nurses-and-midwives-in-nigeria-protocol-for-a-quasi-experimental-noninferiority-study
#12
Kate Reiss, Suzanne Penfold, Olalere Alabi, Moazzam Ali, Kristen Hopkins, Thoai Dinh Ngo, Kingsley Odogwu, Megan Douthwaite, Onoriode Ezire, Uko Udoh, Effiom Effiom, Erik S Munroe
BACKGROUND: As part of its Family Planning 2020 commitment, the Nigerian government is aiming for a contraceptive prevalence rate of 36% by 2018, and in 2014, approved a policy to allow community health extension workers (CHEWs), in addition to doctors, nurses, and midwives, to provide contraceptive subdermal implants. There is a lack of rigorous evidence on the safety of long-acting reversible contraceptive provision, such as implants, among lower cadres of health providers. OBJECTIVE: This study aimed to compare implant provision by CHEWs versus nurses and midwives up to 14 days post insertion...
March 2, 2018: JMIR Research Protocols
https://www.readbyqxmd.com/read/29496297/the-relationship-between-progestin-hormonal-contraception-and-depression-a-systematic-review
#13
REVIEW
Brett L Worly, Tamar L Gur, Jonathan Schaffir
OBJECTIVE: We performed a systematic review to look for an association between progestin-only contraception and depression. METHODS: We searched PubMed, Ovid and Web of Science for English-language articles including progestin-only contraception and depression from database inception to September 2016. We evaluated study quality with the procedures guiding reviews for the United States Preventive Services Task Force and the Cochrane Risk of Bias Tools. We included studies that evaluated progestin-only contraception and depression, focusing on externally validated depression measures...
February 20, 2018: Contraception
https://www.readbyqxmd.com/read/29409943/pediatricians-knowledge-and-practices-related-to-long-acting-reversible-contraceptives-for-adolescent-girls
#14
Risa L Fridy, Sofya Maslyanskaya, Sylvia Lim, Susan M Coupey
STUDY OBJECTIVE: A 2014 American Academy of Pediatrics (AAP) policy statement identified long-acting reversible contraceptives (LARCs) as first-line choices for adolescents, but pediatricians' current knowledge and practices about intrauterine devices (IUDs) and subdermal contraceptive implants (Implants) is unknown. We aimed to characterize pediatricians' knowledge and practices about LARCs for adolescents. DESIGN, SETTING, AND PARTICIPANTS: Cross-sectional online survey emailed to a convenience sample of AAP member pediatricians in New York, Utah, Illinois, and Kansas in 2015 and 2016...
February 1, 2018: Journal of Pediatric and Adolescent Gynecology
https://www.readbyqxmd.com/read/29399422/lessons-learnt-from-the-introduction-of-the-contraceptive-implant-in-south-africa
#15
M Pleaner, C Morroni, J Smit, N Lince-Deroche, M Chersich, S Mullick, D Pillay, M Makua, H Rees
In 2014, South Africa (SA) introduced the subdermal contraceptive implant with the aim of expanding the contraceptive method mix and availability of long-acting reversible methods in the public sector. Three years on, concerns have been raised about the decline in uptake, early implant removals and challenges in service delivery. This article explores the lessons learnt from the introduction of contraceptive technologies elsewhere and applies these to the SA context. Drawing on the World Health Organization’s conceptual framework for the introduction of new contraceptive methods, and subsequent literature on the topic, lessons are classified into six cross-cutting themes...
October 1, 2017: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
https://www.readbyqxmd.com/read/29397799/gaps-in-monitoring-systems-for-implanon-nxt-services-in-south-africa-an-assessment-of-12-facilities-in-two-districts
#16
D Pillay, C Morroni, M Pleaner, O Adeogba, M Chersich, N Naidoo, S Mullick, H Rees
Background. Implanon NXT, a long-acting subdermal contraceptive implant, was introduced in South Africa (SA) in early 2014 as part of an expanded contraceptive method mix. After initial high levels of uptake, reports emerged of frequent early removals and declines in use. Monitoring of progress and challenges in implant service delivery could identify aspects of the programme that require strengthening. Objectives. To assess data management and record keeping within implant services at primary care facilities...
October 1, 2017: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
https://www.readbyqxmd.com/read/29397681/uptake-and-early-removals-of-implanon-nxt-in-south-africa-perceptions-and-attitudes-of-healthcare-workers
#17
O Adeagbo, S Mullick, D Pillay, M Chersich, C Morroni, N Naidoo, M Pleaner, H Rees
Background. The South African (SA) government introduced Implanon NXT, a long-acting subdermal contraceptive implant, in 2014 to expand contraceptive choice. Following an initial high uptake, its use declined considerably amid reports of early removals and frequent side-effects. We examine providers’ perceptions of training and attitudes towards Implanon NXT, as well as their views on the causes of early removals and the impact on the implant service. Objective. To assess healthcare providers’ perceptions and attitudes towards implant services in SA...
October 1, 2017: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
https://www.readbyqxmd.com/read/29310336/removal-of-a-subdermal-contraceptive-implant-implanon-nxt-that-migrated-to-the-axilla-by-c-arm-guidance-a-case-report-and-review-of-the-literature
#18
REVIEW
Ji Ung Park, Han Sol Bae, Seung Mi Lee, Jaehoon Bae, Jeong Woo Park
RATIONALE: To report the distant migration of a subdermal contraceptive implant and to suggest that C arm-guided technique is one of the feasible options for removal of the device migrated to the axilla. PATIENT CONCERNS: A 41-year-old multipara with tingling sensation in the left axilla was referred for removal of an Implanon NXT which could not be palpated by physical examination or detected by ultrasound scanning. Finally, the device was detected by computed tomography and found migrating to the left axilla...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29309985/peripheral-nerve-injury-associated-with-a-subdermal-contraceptive-implant-illustrative-cases-and-systematic-review-of-literature
#19
REVIEW
Pierre Laumonerie, Laurent Blasco, Meagan E Tibbo, Olivier Leclair, Panagiotis Kerezoudis, Elodie Chantalat, Pierre Mansat
BACKGROUND: Despite demonstrable safety and efficacy of subdermal contraceptive implants (SCIs), both insertion and removal of SCIs in the arm have been associated with neurovascular complications. The aim of this study was to investigate type and prognosis of nerve injuries associated with SCIs. METHODS: We performed a comprehensive search of 4 electronic databases for studies pertaining to patients with nerve injury and concurrent SCI. Studies published between January 1987 and June 2017 were included...
March 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29215509/interval-female-sterilization
#20
REVIEW
Gretchen S Stuart, Shanthi S Ramesh
Female sterilization is relied on by nearly one in three women aged 35-44 years in the United States. Sterilization procedures are among the most common procedures that obstetrician-gynecologists perform. The most frequent sterilization procedures include postpartum tubal ligation, laparoscopic tubal disruption or salpingectomy, and hysteroscopic tubal occlusion. The informed consent process for sterilization is crucial and requires shared decision-making between the patient and the health care provider. Counseling should include the specific risks and benefits of the specific surgical approaches...
January 2018: Obstetrics and Gynecology
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