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https://www.readbyqxmd.com/read/28343313/spontaneous-cervical-intradural-disc-herniation-presenting-with-brown-s%C3%A3-quard-and-horner-s-syndrome-lesson-learned-from-a-very-unique-case
#1
Irene Baudracco, Gordan Grahovac, Vittorio M Russo
PURPOSE: Cervical spontaneous intradural disc herniation (IDH) is an extremely rare condition. We describe a unique case of a patient presenting with a Brown-Séquard syndrome (BSS) and Horner's syndrome (HS). This study aimed to report an unusual case of spontaneous cervical intradural disc herniation that presented with Horner's and Brown-Séquard syndrome (BSS) and discuss difficulties in preoperative diagnosis and treatment difficulties of intradural cervical disc. METHODS: Notes and images review, and analysis of the relevant literature...
March 25, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28343269/neophobia-is-negatively-related-to-reversal-learning-ability-in-females-of-a-generalist-bird-of-prey-the-chimango-caracara-milvago-chimango
#2
Jorgelina María Guido, Laura Marina Biondi, Aldo Ivan Vasallo, Rubén Nestor Muzio
In an ever-changing environment, the ability to adapt choices to new conditions is essential for daily living and ultimately, for survival. Behavioural flexibility allows animals to maximise survival and reproduction in novel settings by adjusting their behaviour based on specific information and feedback acquired in their current environments. However, a growing body of evidence indicates that an individual's personality type can limit the extent to which the individual might behave flexibly, by influencing the way an individual pays attention to novelty and how much information it collects and stores, which in turn affects the individual's decision-making and learning process...
March 25, 2017: Animal Cognition
https://www.readbyqxmd.com/read/28342851/site-specific-photocoupling-of-pbpa-mutated-scfv-antibodies-for-use-in-affinity-proteomics
#3
Mattias Brofelth, Lars Wagner Städe, Anna Isinger Ekstrand, Linn Petersson Edfeldt, Rebeka Kovačič, Thorbjørn Terndrup Nielsen, Kim Lambertsen Larsen, Laurent Duroux, Christer Wingren
Recombinant antibody libraries can provide a source of renewable and high-performing binders tailored for use in affinity proteomics. In this context, the process of generating site-specific 1:1 tagging/functionalization and/or orientated surface immobilization of antibodies has, however, proved to be challenging. Hence, novel ways of generating such engineered antibodies for use in affinity proteomics could have a major impact on array performance. In this study, we have further tailored the design of human recombinant scFv antibodies for site-specific photocoupling through the use of an unnatural amino acid (UAA) and the Dock'n'Flash technology...
March 22, 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/28342716/immediate-postpartum-intrauterine-device-and-implant-program-outcomes-a-prospective-analysis
#4
Jennifer L Eggebroten, Jessica N Sanders, David K Turok
BACKGROUND: In-hospital placement of intrauterine devices (IUD) and contraceptive implants following vaginal and cesarean delivery is increasingly popular and responds to maternal motivation for highly effective postpartum contraception. Immediate postpartum IUD insertion is associated with higher expulsion than interval placement, but emerging evidence suggests that the LNG IUD may have a higher expulsion rate than the Cu IUD. OBJECTIVE: This study evaluated in-hospital provision, expulsion and six month continuation of immediate postpartum copper T380 IUDs (Cu IUD), levonorgestrel (LNG) IUDs, and contraceptive implants...
March 22, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28342675/the-digital-heart-manual-a-pilot-study-of-an-innovative-cardiac-rehabilitation-programme-developed-for-and-with-users
#5
C Deighan, L Michalova, C Pagliari, J Elliott, L Taylor, H Ranaldi
OBJECTIVE: Patients are seeking greater choice and flexibility in how they engage with self-management programmes. While digital innovations offer opportunities to deliver supportive interventions to patients undergoing cardiac rehabilitation little is known about how accessible, useful and acceptable they are for this group. This project developed a digital version of a leading evidenced cardiac rehabilitation programme, the Heart Manual (HM). The prototype was developed and evaluated iteratively in collaboration with end users...
March 10, 2017: Patient Education and Counseling
https://www.readbyqxmd.com/read/28342434/-mothers-talk-part-unless-told-of-voluntary-abortion
#6
José Manuel Hernández Garre, Isabel María Aznar Mula, Paloma Echevarría Pérez
The aim of the study was to investigate the experiences linked to the post-abortion syndrome in mothers who have had a voluntary abortion. A phenomenological qualitative approach to collect the experiences of mothers who had voluntarily interrupted their pregnancy was used. The research technique was the semistructured interviews with women who had contacted different association's help of the Murcia region for support after experiencing symptoms consistent with post-abortion syndrome. The testimonies show feminist or utilitarian arguments to justify the decision to abort, they talk about a system, to some extent, mercantilist that has no real intention of giving real life choices...
January 2017: Cuadernos de Bioética: Revista Oficial de la Asociación Española de Bioética y Ética Médica
https://www.readbyqxmd.com/read/28340500/advanced-practice-registered-nurses-and-long-acting-reversible-contraception
#7
Patricia J Kelly, An-Lin Cheng, Kimberly Carlson, Jacki Witt
INTRODUCTION: Advanced practice registered nurses (APRNs) are in an excellent position to address the high rates of unintended pregnancy in the United States by providing long-acting reversible contraceptives (LARCs). These methods are significant in their effectiveness in preventing pregnancy in individual women and in having population-level effects on unintended pregnancy. The aim of this study was to learn more about APRN practices around long-acting reversible contraception and influences on those practices...
March 24, 2017: Journal of Midwifery & Women's Health
https://www.readbyqxmd.com/read/28340454/pea-cultivar-and-wheat-residues-affect-carbon-nitrogen-dynamics-in-pea-triticale-intercropping-a-microcosms-approach
#8
Antonella Scalise, Valentini A Pappa, Antonio Gelsomino, Robert M Rees
The underlying mechanisms by which legume cultivars contribute to nitrous oxide (N2O) generation are poorly understood. The aim of the present study was to explore the effects of two pea cultivars (Zero4 and Nitouche) intercropped with triticale, with or without wheat (Triticum aestivum) residues incorporation, on soil C and N dynamics, on bacterial community structure and their links with N2O emissions. Monocrops and bare soil (no plant) treatments were used as an additional control in order to account for the level of mineralisation between treatments...
March 21, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28340375/repetitive-tms-in-right-sensorimotor-areas-affects-the-selection-and-completion-of-contralateral-movements
#9
Maria Gutierrez-Herrera, Styrmir Saevarsson, Thomas Huber, Joachim Hermsdörfer, Waltraud Stadler
Although the existence of directional motor deficits (DMD) associated with movement planning and/or execution seems to be widely recognized, neglect and single cell studies examining their neuroanatomical foundation have produced contradictory and inconclusive findings. The present study assessed the occurrence of DMD following the application of repetitive transcranial magnetic stimulation (rTMS) over two regions, as commonly reported in the neglect literature, namely the right middle frontal gyrus (rMFG) and the right angular gyrus (rAG)...
February 24, 2017: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
https://www.readbyqxmd.com/read/28340311/early-clinical-efficacy-comparison-study-of-gamma3-nail-percutaneous-compression-plate-pccp-and-femoral-head-replacement-fhr-treatment-on-senile-unstable-intertrochanteric-fractures
#10
Shaofeng Yang, Yanan Liu, Tongqi Yang, Jun Zou, Huilin Yang
PURPOSE: This study aimed to analyze the early clinical efficacy of Gamma 3 nail, percutaneous compression plate (PCCP) and femoral head replacement (FHR) treatments on senile unstable intertrochanteric fractures. MATERIALS AND METHODS: Totally 116 patients were included to perform an retrospective study, which involved analysis of the operation time, intraoperative blood loss, and hemoglobin reduction on the first postoperative day compared with preoperative levels, fracture gap, neck shaft angle and tip apex distance on the first postoperative X-ray, hospital stay, time from surgery to mobilization, Harris hip scores and Barthel index six months after operation, and complications postoperative meanwhile were evaluated respectively among three groups...
February 10, 2017: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/28340103/diagnosis-to-ablation-time-as-a-predictor-of-success-early-choice-for-pulmonary-vein-isolation-and-long-term-outcome-in-atrial-fibrillation-results-from-the-middelheim-pvi-registry
#11
Y De Greef, B Schwagten, G B Chierchia, C de Asmundis, D Stockman, I Buysschaert
Aims: The aim of the study is to define long-term outcome of pulmonary vein isolation (PVI) in atrial fibrillation (AF) and to determine whether time window between AF diagnosis and PVI affects outcome. Methods and results: Consecutive AF patients undergoing PVI (2006-14) were followed for 5 years. Primary outcome was clinical success, defined as freedom of documented AF without anti-arrhythmic drugs respecting a 1-month blanking period. A 1000 patients were included (age 60 ± 10 years, CHA2DS2-VASc score 1 ± 1)...
March 2, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28340057/long-term-outcome-of-pulmonary-vein-isolation-in-patients-with-paroxysmal-atrial-fibrillation-and-brugada-syndrome
#12
Giacomo Mugnai, Burak Hünük, Erwin Ströker, Diego Ruggiero, Hugo Enrique Coutino-Moreno, Ken Takarada, Valentina De Regibus, Rajin Choudhury, Juan Pablo Abugattas de Torres, Darragh Moran, Saverio Iacopino, Pasquale Filannino, Giulio Conte, Juan Sieira, Jan Poelaert, Stefan Beckers, Pedro Brugada, Carlo de Asmundis, Gian-Battista Chierchia
Aims: The therapeutical management of atrial fibrillation (AF) in the setting of Brugada syndrome (BS) might be challenging as many antiarrhythmic drugs (AADs) with sodium channel blocking properties might lead to to the development of ventricular arrhythmias. This study sought to evaluate the clinical outcome in a consecutive series of patients with BS having undergone pulmonary vein (PV) isolation by means of radiofrequency (RF) or cryoballoon (CB) ablation and the efficacy of catheter ablation for preventing inappropriate interventions delivered by implantable cardioverter defibrillators (ICD) on a 3-year follow up...
March 9, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28339990/detecting-thresholds-for-bitter-umami-and-sweet-tastants-in-broiler-chicken-using-a-2-choice-test-method
#13
Shira L Cheled-Shoval, Naama Reicher, Masha Y Niv, Zehava Uni
The sense of taste has a key role in nutrient sensing and food intake in animals. A standardized and simple method for determination of tastant-detection thresholds is required for chemosensory research in poultry. We established a 24-h, 2-alternative, forced-choice solution-consumption method and applied it to measure detection thresholds for 3 G-protein-coupled receptor-mediated taste modalities-bitter, sweet, and umami-in chicken. Four parameters were used to determine a significant response: 1) tastant-solution consumption; 2) water (tasteless) consumption; 3) total consumption (tastant and water together); 4) ratio of tastant consumption to total consumption...
March 2, 2017: Poultry Science
https://www.readbyqxmd.com/read/28339860/outcomes-with-single-coil-versus-dual-coil-implantable-cardioverter-defibrillators-a-meta-analysis
#14
Nicholas Sunderland, Amit Kaura, Francis Murgatroyd, Para Dhillon, Paul A Scott
Aims: Dual-coil implantable cardioverter defibrillator (ICD) leads have traditionally been used over single-coil leads due to concerns regarding high defibrillation thresholds (DFT) and consequent poor shock efficacy. However, accumulating evidence suggests that this position may be unfounded and that dual-coil leads may also be associated with higher complication rates during lead extraction. This meta-analysis collates data comparing dual- and single-coil ICD leads. Methods and results: Electronic databases were systematically searched for randomized controlled trials (RCT) and non-randomized studies comparing single-coil and dual-coil leads...
February 27, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28339680/operations-management-in-distribution-networks-within-a-smart-city-framework
#15
Raffaele Cerulli, Renata Paola Dameri, Anna Sciomachen
This article studies a vehicle routing problem with environmental constraints that are motivated by the requirements for sustainable urban transport. The empirical research presents a fleet planning problem that takes into consideration both minimum cost vehicle routes and minimum pollution. The problem is formulated as a mixed integer linear programming model and experimentally validated using data collected from a real situation: a grocery company delivering goods ordered via e-channels to customers spread in the urban and metropolitan area of Genoa smart city...
February 20, 2017: Mathematical Medicine and Biology: a Journal of the IMA
https://www.readbyqxmd.com/read/28339580/the-integration-of-orthodontic-miniscrews-under-mechanical-loading-a-pre-clinical-study-in-rabbit
#16
B Giuliano Maino, Alberto Di Blasio, Davide Spadoni, Francesca Ravanetti, Carlo Galli, Antonio Cacchioli, Christos Katsaros, Mauro Gandolfini
Introduction: Orthodontic miniscrews are an increasingly popular choice to achieve absolute anchorage. The temporary use of miniscrews and their recent introduction have limited the debate over the biological aspect of the materials to that of the surface that permeates the field of dental implants. The aim of the present study was to investigate the integration of grade 5 titanium mini-implants with machined or sand blasted acid etched surface (SAE) under mechanical load in a rabbit tibia model of implant integration...
January 18, 2017: European Journal of Orthodontics
https://www.readbyqxmd.com/read/28339493/timely-meta-analysis-on-the-efficacy-of-adoptive-immunotherapy-for-hepatocellular-carcinoma-patients-after-curative-therapy
#17
Han-Yue Mo, Ying-Yang Liao, Xue-Mei You, Alessandro Cucchetti, Bao-Hong Yuan, Ru-Hong Li, Jian-Hong Zhong, Le-Qun Li
AIMS: The role of adoptive immunotherapy (AIT) for patients with hepatocellular carcinoma (HCC) who have received curative therapy is still not well illustrated. This timely meta-analysis aims to update the current evidence on efficacy and safety of AIT for patients with HCC who have received curative therapy. METHODS: We searched PubMed, EMBASE, Scopus and the Cochrane Library Through January 2017 for relevant studies. Mortality and tumor recurrence were compared between patients with or without adjuvant AIT...
2017: PloS One
https://www.readbyqxmd.com/read/28339339/use-of-dietary-supplements-improved-diet-quality-but-not-cardiovascular-and-nutritional-biomarkers-in-socioeconomically-diverse-african-american-and-white-adults
#18
Marie Fanelli Kuczmarski, May A Beydoun, Emily Stave Shupe, Ryan T Pohlig, Alan B Zonderman, Michele K Evans
Knowledge of the contribution of supplements to overall nutritional health is limited. The research objectives were to describe motivations for use of dietary supplements by African Americans and Whites examined in the Healthy Aging in Neighborhoods of Diversity across the Life Span (HANDLS) study and to determine if supplements provided beneficial effects to micronutrient diet quality and nutritional and cardiovascular biomarkers. The majority of the HANDLS study population were smokers, overweight or obese, and self-reported their health as poor to good...
March 24, 2017: Journal of Nutrition in Gerontology and Geriatrics
https://www.readbyqxmd.com/read/28339327/raising-public-awareness-of-clinical-trials-development-of-messages-for-a-national-health-communication-campaign
#19
Holly A Massett, David M Dilts, Robert Bailey, Jennifer Berktold, Rebecca Ledsky, Nancy L Atkinson, Grace Mishkin, Andrea Denicoff, Rose Mary Padberg, Marin P Allen, Karen Silver, Kelli Carrington, Lenora E Johnson
Clinical trials are essential for developing new and effective treatments and improving patient quality of life; however, many trials cannot answer their primary research questions because they fall short of their recruitment goals. This article reports the results of formative research conducted in two populations, the public and primary care physicians, to identify messages that may raise awareness and increase interest in clinical trials and be used in a national communication campaign. Results suggested that participants were primarily motivated to participate in clinical trials out of a self-interest to help themselves first...
March 24, 2017: Journal of Health Communication
https://www.readbyqxmd.com/read/28338913/assessing-the-impact-of-unmeasured-confounding-for-binary-outcomes-using-confounding-functions
#20
Jessica Kasza, Rory Wolfe, Tibor Schuster
A critical assumption of causal inference is that of no unmeasured confounding: for estimated exposure effects to have valid causal interpretations, a sufficient set of predictors of exposure and outcome must be adequately measured and correctly included in the respective inference model(s). In an observational study setting, this assumption will often be unsatisfied, and the potential impact of unmeasured confounding on effect estimates should be investigated. The confounding function approach allows the impact of unmeasured confounding on estimates to be assessed, where unmeasured confounding may be due to unmeasured confounders and/or biases such as collider bias or information bias...
March 3, 2017: International Journal of Epidemiology
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