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https://www.readbyqxmd.com/read/28324641/preparation-of-a-non-woven-poly-%C3%AE%C2%B5-caprolactone-fabric-with-partially-embedded-apatite-surface-for-bone-tissue-engineering-applications-by-partial-surface-melting-of-poly-%C3%AE%C2%B5-caprolactone-fibers
#1
In Ae Kim, Sang-Hoon Rhee
This paper describes a novel method for the preparation of a biodegradable non-woven poly(ε-caprolactone) fabric with a partially-embedded apatite surface designed for application as a scaffold material for bone tissue engineering. The non-woven poly(ε-caprolactone) fabric was generated by the electro-spinning technique and then apatite was coated in simulated body fluid after coating the PVA solution containing CaCl2 ·2H2 O. The apatite crystals were partially- or fully-embedded into the thermoplastic poly(ε-caprolactone) fibers by controlling the degree of poly(ε-caprolactone) fiber surface melting in a convection oven...
March 21, 2017: Journal of Biomedical Materials Research. Part A
https://www.readbyqxmd.com/read/28283718/measuring-transdermal-glucose-levels-in-neonates-by-passive-diffusion-an-in-vitro-porcine-skin-model
#2
Cristina Tiangco, Abhay Andar, Juliana Quarterman, Xudong Ge, Fortunato Sevilla, Govind Rao, Audra Stinchcomb, Annette Bunge, Leah Tolosa
Current glucose monitoring techniques for neonates rely heavily on blood glucose monitors which require intermittent blood collection through skin-penetrating pricks on the heel or fingers. This procedure is painful and often not clinically conducive, which presents a need for a noninvasive method for monitoring glucose in neonates. Our motivation for this study was to develop an in vitro method for measuring passive diffusion of glucose in premature neonatal skin using a porcine skin model. Such a model will allow us to initially test new devices for noninvasive glucose monitoring without having to do in vivo testing of newborns...
March 10, 2017: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/28278501/standardization-of-an-in-vitro-model-for-evaluating-the-bioavailability-of-topically-applied-compounds-on-damaged-skin-application-to-sunscreen-analysis
#3
Carine Jacques-Jamin, Corinne Jeanjean-Miquel, Anaïs Domergue, Sandrine Bessou-Touya, Hélène Duplan
BACKGROUND: Information is lacking on the dermal penetration of topically applied formulations on in vitro skin models, under conditions where the stratum corneum (SC) is damaged. Therefore, we have developed a standardized in vitro barrier-disrupted skin model using tape stripping. METHODS: Different tape stripping conditions were evaluated using histology, transepidermal water loss, infrared densitometry, and caffeine absorption. RESULTS: The effects of tape stripping were comparable using pig and human skin...
March 10, 2017: Skin Pharmacology and Physiology
https://www.readbyqxmd.com/read/28277705/the-role-of-social-closeness-during-tape-stripping-to-facilitate-skin-barrier-recovery-preliminary-findings
#4
Hayley Robinson, Abhimati Ravikulan, Urs M Nater, Nadine Skoluda, Paul Jarrett, Elizabeth Broadbent
OBJECTIVE: Social support is known to reduce the negative effects of stress on health, but there is mixed evidence for the effects of social support on wound healing. This study aimed to investigate whether undergoing a task designed to promote social closeness with a fellow participant and being paired with that person during a tape-stripping procedure could reduce stress and improve skin barrier recovery compared to going through tape stripping alone. METHOD: Seventy-two healthy adults were randomized to either a social closeness condition where participants completed a relationship-building task and tape stripping in pairs or a control condition where they completed tape stripping alone...
March 9, 2017: Health Psychology: Official Journal of the Division of Health Psychology, American Psychological Association
https://www.readbyqxmd.com/read/28246113/disseminated-cysticercosis-incidentally-diagnosed-in-a-patient-of-fracture-shaft-of-femur
#5
Noora Saeed, Aaliya Ehsan, Shaista M Vasenwala
Cysticercosis is caused by the larval form of Taenia solium tape worm, cysticercus cellulose. The life cycle of T. solium consists of 2 host, the definite host is a man who harbours the adult forms of the worm in the intestine, while the intermediate host is the pig, where the larval form (cysticercus cellulose) is found in the skeletal muscle. Cysticercosis develops when human beings incidentally become the intermediate host and the eggs mature within their small intestine. The route of entry of the eggs into the human intestine may occur through autoinfection or by ingestion of contaminated food or water...
February 28, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28240727/under-pressure-the-utility-of-spacers-in-univalved-fiberglass-casts
#6
Kevin Kleis, John A Schlechter, Joshua D Doan, Christine L Farnsworth, Eric W Edmonds
BACKGROUND: Univalving fiberglass casts after fracture manipulation or extremity surgery reduces the risk of developing compartment syndrome (CS). Previous experiments have demonstrated that univalving decreases intracompartmental pressures (ICPs), but increases the risk for loss of fracture reduction due to altering the mechanical properties of the cast. The purpose of this study was to correlate cast valve width within a univalved cast model to decreasing ICP. METHODS: Saline bags (1 L) were covered with stockinette, Webril, and fiberglass tape then connected to an arterial pressure line monitor...
February 24, 2017: Journal of Pediatric Orthopedics
https://www.readbyqxmd.com/read/28171796/increased-recovery-of-touch-dna-evidence-using-fta-paper-compared-to-conventional-collection-methods
#7
Irina A Kirgiz, Cassandra Calloway
Tape lifting and FTA paper scraping methods were directly compared to traditional double swabbing for collecting touch DNA from car steering wheels (n = 70 cars). Touch DNA was collected from the left or right side of each steering wheel (randomized) using two sterile cotton swabs, while the other side was sampled using water-soluble tape or FTA paper cards. DNA was extracted and quantified in duplicate using qPCR. Quantifiable amounts of DNA were detected for 100% of the samples (n = 140) collected independent of the method...
January 31, 2017: Journal of Forensic and Legal Medicine
https://www.readbyqxmd.com/read/28079363/fluorescence-development-of-latent-fingerprint-with-conjugated-polymer-nanoparticles-in-aqueous-colloidal-solution
#8
Hong Chen, Rong-Liang Ma, Yun Chen, Li-Juan Fan
Poly(p-phenylenevinylene) (PPV) nanoparticles in aqueous colloidal solution have been prepared via a modified Wessling method, with the addition of surfactant. The fluorescent colloidal solution was used as the developing solution to develop the fingerprints on different substrates. The developing process was accomplished simply by immersing the substrates into developing solution and then taking out, followed by rinsing with deionized water. The initial study about the fingerprints on the adhesive tapes showed that the developing solution is very effective in fluorescence development on both fresh and aged visible fingerprints; and such an effect was negligibly affected by treating the fingerprints with water or other organic solvents, whether before developing or after...
January 24, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28067487/investigation-into-pseudo-capacitance-behavior-of-glycoside-containing-hydrogels
#9
Nachiket Raravikar, Andrew Dobos, Eshwaran Narayanan, Taraka Sai Pavan Grandhi, Saurabh Mishra, Kaushal Rege, Michael Goryll
Electrochemical pseudocapacitors are an attractive choice for energy storage applications because they offer higher energy densities than electrostatic or electric double layer capacitors. They also offer higher power densities in shorter durations of time, as compared to batteries. Recent efforts on pseudocapacitors include biocompatible hydrogel electrolytes and transition metal electrodes for implantable energy storage applications. Pseudocapacitive behavior in these devices has been attributed to the redox reactions that occur within the electric double layer, which is formed at the electrode-electrolyte interface...
February 1, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28048019/su-f-t-76-total-skin-electron-therapy-an-end-to-end-examination-of-the-absolute-dosimetry-with-a-rando-phantom
#10
G Cui, J Ha, S Zhou, J Cui, A Shiu
PURPOSE: To examine and validate the absolute dose for total skin electron therapy (TSET) through an end-to-end test with a Rando phantom using optically stimulated luminescent dosimeters (OSLDs) and EBT3 radiochromic films. METHODS: A Varian Trilogy linear accelerator equipped with the special procedure 6 MeV HDTSe- was used to perform TSET irradiations using a modified Stanford 6-dual-field technique. The absolute dose was calibrated using a Markus ion chamber at a reference depth of 1...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046781/su-f-t-93-breast-surface-dose-enhancement-using-a-clinical-prone-breast-board
#11
M Guerra, G Jozsef
PURPOSE: The use of specialized patient set-up devices in radiotherapy, such as prone breast boards, may have unwanted dosimetric effects. The goal of this study was to evaluate the effect of a clinically used prone breast board on skin dose due to buildup. METHODS: GafChromic film (EBT3) was used for dose measurements on the surface of a solid water phantom shaped to mimic the curvature of the breast. We investigated two setup scenarios: the medial field border placed at the medial edge of the board and 1 cm contralaterally from that edge...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28012990/assessment-of-skin-barrier-function-and-biochemical-changes-of-ex-vivo-human-skin-in-response-to-physical-and-chemical-barrier-disruption
#12
Nadine Döge, Araks Avetisyan, Sabrina Hadam, Eva Katharina Barbosa Pfannes, Fiorenza Rancan, Ulrike Blume-Peytavi, Annika Vogt
Topical dermatotherapy is intended to be used on diseased skin. Novel drug delivery systems even address differences between intact and diseased skin underlining the need for pre-clinical assessment of different states of barrier disruption. Herein, we studied how short-term incubation in culture media compared to incubation in humidified chambers affects human skin barrier function and viability. On both models we assessed different types and intensities of physical and chemical barrier disruption methods with regard to structural integrity, biophysical parameters and cytokine levels...
December 21, 2016: European Journal of Pharmaceutics and Biopharmaceutics
https://www.readbyqxmd.com/read/28008987/a-bio-enabled-maximally-mild-layer-by-layer-kapton-surface-modification-approach-for-the-fabrication-of-all-inkjet-printed-flexible-electronic-devices
#13
Yunnan Fang, Jimmy G D Hester, Wenjing Su, Justin H Chow, Suresh K Sitaraman, Manos M Tentzeris
A bio-enabled, environmentally-friendly, and maximally mild layer-by-layer approach has been developed to surface modify inherently hydrophobic Kapton HN substrates to allow for great printability of both water- and organic solvent-based inks thus facilitating the full-inkjet-printing of flexible electronic devices. Different from the traditional Kapton surface modification approaches which are structure-compromising and use harsh conditions to target, and oxidize and/or remove part of, the surface polyimide of Kapton, the present Kapton surface modification approach targeted the surface electric charges borne by its additive particles, and was not only the first to utilize environmentally-friendly clinical biomolecules to build up a thin film of protamine-heparin complex on Kapton, but also the first to be conducted under minimally destructive and maximally mild conditions...
December 23, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27966367/novel-sio2-h2ti2o5%C3%A2-h2o-nanochain-composite-with-high-uv-visible-photocatalytic-activity-for-supertransparent-multifunctional-thin-films
#14
Lin Yao, Junhui He, Tong Li, Tingting Ren
In the current work, a peroxo titanium complex (PTC) solution was used as a novel water-soluble precursor to fabricate H2Ti2O5·H2O and the SiO2/H2Ti2O5·H2O-nanochain composite at low temperature (90-100 °C). The average width of H2Ti2O5·H2O nanochains is 4.5 ± 1.5 nm. Under full-spectrum irradiation, the Si/Ti-nanochain composite showed good UV-visible light absorption and excellent photocatalytic activity, which is 2.8 times that of P25. In the composite, SiO2 not only contributes to the formation of nanochains and improves the catalytic performance of H2Ti2O5·H2O but also reduces the refractive index of the complex...
December 27, 2016: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/27934975/xurography-for-microfluidics-on-a-reactive-solid
#15
Amélie Neuville, Louis Renaud, Thi Thuy Luu, Mona Wetrhus Minde, Espen Jettestuen, Jan Ludvig Vinningland, Aksel Hiorth, Dag Kristian Dysthe
In this paper, we propose a simple method to embed transparent reactive materials in a microfluidic cell, and to observe in situ the dissolution of the material. As an example, we show how to obtain the dissolution rate of a calcite window of optical quality, dissolved in water and hydrochloric acid (HCl). These fluids circulate at controlled flowrates in a channel which is obtained by xurography: double sided tape is cut out with a cutter plotter and placed between the calcite window and a non-reactive support...
December 9, 2016: Lab on a Chip
https://www.readbyqxmd.com/read/27917258/modeling-the-qbo-improvements-resulting-from-higher-model-vertical-resolution
#16
Marvin A Geller, Tiehan Zhou, D Shindell, R Ruedy, I Aleinov, L Nazarenko, N L Tausnev, M Kelley, S Sun, Y Cheng, R D Field, G Faluvegi
Using the NASA Goddard Institute for Space Studies (GISS) climate model, it is shown that with proper choice of the gravity wave momentum flux entering the stratosphere and relatively fine vertical layering of at least 500 m in the upper troposphere-lower stratosphere (UTLS), a realistic stratospheric quasi-biennial oscillation (QBO) is modeled with the proper period, amplitude, and structure down to tropopause levels. It is furthermore shown that the specified gravity wave momentum flux controls the QBO period whereas the width of the gravity wave momentum flux phase speed spectrum controls the QBO amplitude...
September 2016: Journal of Advances in Modeling Earth Systems
https://www.readbyqxmd.com/read/27859284/comparison-of-rehydration-techniques-for-fingerprinting-the-deceased-after-mummification
#17
Chun-Chieh Chen, Chao-Kai Yang, Chun-Yu Chen, Henry C Lee, Sheng-Meng Wang
Postmortem decay causes fingertip decomposition, desiccation, shriveling, and rigidity, reducing the possibility of obtaining sufficiently clear fingerprints for identification. In this study, five rehydration solutions (ammonium hydroxide, sodium carbonate, potassium hydroxide, urea, and warm water) followed by three fingerprint recording methods (photograph, inking roll, and dusting tape) were investigated to process mummified fingertips from an unidentified cadaver. The results show that sodium carbonate treatment is the most effective for minutiae restoration, followed by ammonium hydroxide treatment...
January 2017: Journal of Forensic Sciences
https://www.readbyqxmd.com/read/27846299/hyperglycemia-induces-skin-barrier-dysfunctions-with-impairment-of-epidermal-integrity-in-non-wounded-skin-of-type-1-diabetic-mice
#18
Junko Okano, Hideto Kojima, Miwako Katagi, Takahiko Nakagawa, Yuki Nakae, Tomoya Terashima, Takeshi Kurakane, Mamoru Kubota, Hiroshi Maegawa, Jun Udagawa
Diabetes causes skin complications, including xerosis and foot ulcers. Ulcers complicated by infections exacerbate skin conditions, and in severe cases, limb/toe amputations are required to prevent the development of sepsis. Here, we hypothesize that hyperglycemia induces skin barrier dysfunction with alterations of epidermal integrity. The effects of hyperglycemia on the epidermis were examined in streptozotocin-induced diabetic mice with/without insulin therapy. The results showed that dye leakages were prominent, and transepidermal water loss after tape stripping was exacerbated in diabetic mice...
2016: PloS One
https://www.readbyqxmd.com/read/27842544/experiences-and-perceptions-of-ghanaian-midwives-on-labour-pain-and-religious-beliefs-and-practices-influencing-their-care-of-women-in-labour
#19
Lydia Aziato, Hannah Antwi Ohemeng, Cephas N Omenyo
BACKGROUND: Beliefs surrounding pain during childbirth has biblical foundations that contribute to labour pain being viewed as a natural phenomenon. Contemporary health care promotes evidence-based labour pain management but the faith of the midwife may influence her midwifery practice regarding labour pain management. Therefore this study sought to gain in-depth insight into the experiences and perceptions of midwives regarding labour pain and the religious beliefs and practices influencing their care of women in labour in Ghana...
November 14, 2016: Reproductive Health
https://www.readbyqxmd.com/read/27800639/measurement-of-skin-surface-biomakers-by-transdermal-analyses-patch-following-different-in-vivo-models-of-irritation-a-pilot-study
#20
D Falcone, P Spee, K Salk, M Peppelman, P C M van de Kerkhof, P E J van Erp
BACKGROUND/PURPOSE: FibroTx Transdermal Analyses Patch (TAP) is a novel technology for non-invasive measurements of protein biomarkers on the skin surface, in vivo. The aim of this study was to explore the potential of TAP in detecting skin surface biomarkers following mild perturbations, in vivo, using two experimental models: tape stripping, mimicking acute barrier disruption, and histamine iontophoresis, mimicking acute and local inflammation at minimal skin barrier insult. METHODS: Tape stripping and histamine iontophoresis were performed in two separate experiments on the volar forearm of healthy volunteers (n = 27 and n = 10, respectively)...
November 1, 2016: Skin Research and Technology
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