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https://www.readbyqxmd.com/read/28749192/current-review-of-the-sarqol%C3%A2-a-health-related-quality-of-life-questionnaire-specific-to-sarcopenia
#1
Charlotte Beaudart, Jean-Yves Reginster, Anton Geerinck, Médéa Locquet, Olivier Bruyère
Sarcopenia, defined by a progressive and generalized loss of muscle mass and muscle function, is associated with many harmful clinical consequences. Several studies have reported the impact of sarcopenia on health-related quality of life (HRQoL) using generic quality of life (QoL) questionnaires. The results of these observational studies are quite heterogenous. Indeed, generic tools may not be able to detect subtle effects of sarcopenia on QoL. Recently, a sarcopenia-specific HRQoL questionnaire was developed and validated in a population of sarcopenic subjects to more accurately assess the impact of sarcopenia on QoL...
July 27, 2017: Expert Review of Pharmacoeconomics & Outcomes Research
https://www.readbyqxmd.com/read/28748497/a-large-scale-study-on-the-effects-of-sex-on-gray-matter-asymmetry
#2
Christian Núñez, Constantina Theofanopoulou, Carl Senior, Maria Rosa Cambra, Judith Usall, Christian Stephan-Otto, Gildas Brébion
Research on sex-related brain asymmetries has not yielded consistent results. Despite its importance to further understanding of normal brain development and mental disorders, the field remains relatively unexplored. Here we employ a recently developed asymmetry measure, based on the Dice coefficient, to detect sex-related gray matter asymmetries in a sample of 457 healthy participants (266 men and 191 women) obtained from 5 independent databases. Results show that women's brains are more globally symmetric than men's (p < 0...
July 26, 2017: Brain Structure & Function
https://www.readbyqxmd.com/read/28748485/early-onset-first-episode-psychosis-dimensional-structure-of-symptoms-clinical-subtypes-and-related-neurodevelopmental-markers
#3
Maria Giuseppina Petruzzelli, Lucia Margari, Andrea Bosco, Francesco Craig, Roberto Palumbi, Francesco Margari
Despite the growing interest in a dimensional approach to the assessment of symptoms and clinically relevant phenomena in schizophrenia spectrum disorders, very few studies, to date, have examined the dimensional structure of symptoms in early onset first episode psychosis. In the present study, we assessed a sample of 60 children and adolescents of both sexes with first episode schizophrenia spectrum psychosis. A principal component analysis (PCA) of the Positive and Negative Syndrome Scale (PANSS) was performed and the factors obtained were used to carry out a cluster analysis...
July 26, 2017: European Child & Adolescent Psychiatry
https://www.readbyqxmd.com/read/28748447/cross-modal-working-memory-binding-and-l1-l2-word-learning
#4
Shinmin Wang, Richard J Allen, Shin-Yi Fang, Ping Li
The ability to create temporary binding representations of information from different sources in working memory has recently been found to relate to the development of monolingual word recognition in children. The current study explored this possible relationship in an adult word-learning context. We assessed whether the relationship between cross-modal working memory binding and lexical development would be observed in the learning of associations between unfamiliar spoken words and their semantic referents, and whether it would vary across experimental conditions in first- and second-language word learning...
July 26, 2017: Memory & Cognition
https://www.readbyqxmd.com/read/28748334/effect-of-omega-3-and-6-supplementation-on-language-in-preterm-toddlers-exhibiting-autism-spectrum-disorder-symptoms
#5
Kelly W Sheppard, Kelly M Boone, Barbara Gracious, Mark A Klebanoff, Lynette K Rogers, Joseph Rausch, Christopher Bartlett, Daniel L Coury, Sarah A Keim
Delayed language development may be an early indicator of autism spectrum disorder (ASD). Early intervention is critical for children with ASD, and the present study presents pilot data on a clinical trial of omega-3 and -6 fatty acid supplementation and language development, a secondary trial outcome, in children at risk for ASD. We randomized 31 children to receive an omega-3 and -6 supplement or a placebo for 3 months, and measured their language abilities at baseline and after supplementation. Gesture use, but not word production, increased for children in the treatment group more than children in the placebo group...
July 26, 2017: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/28747931/is-the-national-guideline-clearinghouse-a-trustworthy-source-of-practice-guidelines-for-child-and-youth-anxiety-and-depression
#6
Stephanie Duda, Christine Fahim, Peter Szatmari, Kathryn Bennett
OBJECTIVE: Innovative strategies that facilitate the use of high quality practice guidelines (PG) are needed. Accordingly, repositories designed to simplify access to PGs have been proposed as a critical component of the network of linked interventions needed to drive increased PG implementation. The National Guideline Clearinghouse (NGC) is a free, international online repository. We investigated whether it is a trustworthy source of child and youth anxiety and depression PGs. METHOD: English language PGs published between January 2009 and February 2016 relevant to anxiety or depression in children and adolescents (≤ 18 years of age) were eligible...
July 2017: Journal of the Canadian Academy of Child and Adolescent Psychiatry
https://www.readbyqxmd.com/read/28747870/neural-entrainment-and-sensorimotor-synchronization-to-the-beat-in-children-with-developmental-dyslexia-an-eeg-study
#7
Lincoln J Colling, Hannah L Noble, Usha Goswami
Tapping in time to a metronome beat (hereafter beat synchronization) shows considerable variability in child populations, and individual differences in beat synchronization are reliably related to reading development. Children with developmental dyslexia show impairments in beat synchronization. These impairments may reflect deficiencies in auditory perception of the beat which in turn affect auditory-motor mapping, or may reflect an independent motor deficit. Here, we used a new methodology in EEG based on measuring beat-related steady-state evoked potentials (SS-EPs, Nozaradan et al...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/28747295/motivate-a-pretreatment-web-based-program-to-improve-attendance-at-uk-outpatient-services-among-adults-with-eating-disorders
#8
Sarah Muir, Ciarán Newell, Jess Griffiths, Kathy Walker, Holly Hooper, Sarah Thomas, Peter W Thomas, Jon Arcelus, James Day, Katherine M Appleton
BACKGROUND: In the UK, eating disorders affect upward of 725,000 people per year, and early assessment and treatment are important for patient outcomes. Around a third of adult outpatients in the UK who are referred to specialist eating disorder services do not attend, which could be related to patient factors related to ambivalence, fear, and a lack of confidence about change. This lack of engagement has a negative impact on the quality of life of patients and has implications for service costs...
July 26, 2017: JMIR Research Protocols
https://www.readbyqxmd.com/read/28747158/characteristics-of-disability-in-activity-of-daily-living-in-elderly-people-associated-with-locomotive-disorders
#9
Tsutomu Iwaya, Tokuhide Doi, Atsushi Seichi, Yuichi Hoshino, Toru Ogata, Masami Akai
BACKGROUND: Ageing is associated with a decline of motor function and ability to perform daily activities. Locomotive disorders are one of the major disorders resulting in adverse health condition in elderly people. Concept of Locomotive syndrome (LoS) was proposed to tackle the problems and prolong healthy life expectancy of people with locomotive disorders. To develop intervention strategy for LoS it is mandatory to investigate impairments, functional disabilities which people with locomotive disorder experience and to examine relationships among these parameters...
July 26, 2017: BMC Geriatrics
https://www.readbyqxmd.com/read/28747076/a-global-incremental-development-method-for-a-web-based-prostate-cancer-treatment-decision-aid-and-usability-testing-in-a-dutch-clinical-setting
#10
Maarten Cuypers, Romy Ed Lamers, Paul Jm Kil, Regina The, Klemens Karssen, Lonneke V van de Poll-Franse, Marieke de Vries
Many new decision aids are developed while aspects of existing decision aids could also be useful, leading to a sub-optimal use of resources. To support treatment decision-making in prostate cancer patients, a pre-existing evidence-based Canadian decision aid was adjusted to Dutch clinical setting. After analyses of the original decision aid and routines in Dutch prostate cancer care, adjustments to the decision aid structure and content were made. Subsequent usability testing (N = 11) resulted in 212 comments...
July 1, 2017: Health Informatics Journal
https://www.readbyqxmd.com/read/28746756/de-scenting-extinction-the-promise-of-de-extinction-may-hasten-continuing-extinctions
#11
Claudio Campagna, Daniel Guevara, Bernard Le Boeuf
Among the most egregious and discouraging problems of conservation is the rapidly escalating human-caused species extinction rate. "De-extinction" refers to the application of certain cutting-edge techniques for the supposed recovery of lost species and gives the impression that scientists, enlightened and empowered by the miracles of technology, are coming to the rescue. "De-extinction" is the latest example of a long play of language that has given conservation efforts a tragically false sense of accomplishment and has worsened the conservation crisis...
July 2017: Hastings Center Report
https://www.readbyqxmd.com/read/28745080/improving-understanding-of-trigger-points-and-widespread-pressure-pain-sensitivity-in-tension-type-headache-patients-clinical-implications
#12
César Fernández-De-Las-Peñas, Lars Arendt-Nielsen
The underlying etiology of tension type headache (TTH) is not understood. The current paper highlights the etiologic role of muscle trigger points (TrPs) to the development and maintenance of central sensitization in TTH and its clinical repercussion for proper management of these patients. Areas covered: A literature search on Pub Med for English-language published papers between 1990 and May 2017 to provide the most updated data on the topic was conducted. Current literature suggests that the referred pain elicited by active trigger points (TrPs) contributes to the manifestations of TTH...
July 26, 2017: Expert Review of Neurotherapeutics
https://www.readbyqxmd.com/read/28745018/a-comparison-between-linguistic-skills-and-socio-communicative-abilities-in-williams-syndrome
#13
P Alfieri, D Menghini, L Marotta, L De Peppo, L Ravà, F Salvaguardia, C Varuzza, S Vicari
BACKGROUND: Individuals with Williams syndrome (WS) show a disharmonic linguistic profile with a clear pattern of strengths and weaknesses. Despite their sociable nature, atypical socio-communicative abilities and deficits in communication and relationship with others have been found. AIM: The aim of the present study was to investigate whether linguistic skills (LS) were in line with the pragmatic and social use of language and the cognitive development of 32 individuals with WS (18 boys and 14 girls) with a mean chronological age of 12...
July 26, 2017: Journal of Intellectual Disability Research: JIDR
https://www.readbyqxmd.com/read/28744759/do-verbal-children-with-autism-comprehend-gesture-as-readily-as-typically-developing-children
#14
Nevena Dimitrova, Şeyda Özçalışkan, Lauren B Adamson
Gesture comprehension remains understudied, particularly in children with autism spectrum disorder (ASD) who have difficulties in gesture production. Using a novel gesture comprehension task, Study 1 examined how 2- to 4-year-old typically-developing (TD) children comprehend types of gestures and gesture-speech combinations, and showed better comprehension of deictic gestures and reinforcing gesture-speech combinations than iconic/conventional gestures and supplementary gesture-speech combinations at each age...
July 25, 2017: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/28743322/presentation-of-the-coding-and-assessment-system-for-narratives-of-trauma-casnot-application-in-spanish-battered-women-and-preliminary-analyses
#15
Violeta Fernández-Lansac, María Crespo
This study introduces a new coding system, the Coding and Assessment System for Narratives of Trauma (CASNOT), to analyse several language domains in narratives of autobiographical memories, especially in trauma narratives. The development of the coding system is described. It was applied to assess positive and traumatic/negative narratives in 50 battered women (trauma-exposed group) and 50 nontrauma-exposed women (control group). Three blind raters coded each narrative. Inter-rater reliability analyses were conducted for the CASNOT language categories (multirater Kfree coefficients) and dimensions (intraclass correlation coefficients)...
July 26, 2017: Spanish Journal of Psychology
https://www.readbyqxmd.com/read/28742789/evaluation-of-appropriate-venous-thromboembolism-prophylaxis-in-orthopaedic-trauma-patients-with-symptom-driven-vascular-and-radiographic-studies
#16
Christopher M Domes, Anneliese M Schleyer, James M McQueen, Ronald F Pergamit, Daphne M Beingessner
OBJECTIVE: To evaluate venous thromboembolism (VTE) prophylaxis adherence and effectiveness in orthopaedic trauma patients who had vascular or radiographic studies showing deep vein thromboses (DVTs) or pulmonary emboli (PEs). DESIGN: Retrospective review SETTING:: This study was conducted at a level I trauma center that independently services a 5 state region. The medical records of patients treated surgically between July 2010 and March 2013 were interrogated using a technical tool that electronically captures thrombotic event data from vascular and radiologic imaging studies via natural language processing...
July 24, 2017: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/28742448/psychometric-properties-of-the-thai-internalized-stigma-scale-tis-lch-for-care-home-residents
#17
Suhathai Tosangwarn, Philip Clissett, Holly Blake
OBJECTIVES: Living in a care home is a source of stigma in Thai culture, although there is currently no measurement tool in the Thai language specifically designed to assess internalized stigma in care home residents. The Thai Version of Internalized Stigma of Living in a Care Home (TIS-LCH) scale was developed and tested for its psychometric properties among Thai older residents. METHODS: The Thai version of Internalized Stigma of Mental Health Illness (ISMI) Scale was revised into the TIS-LCH by replacing the word of "mental health illness" to "living in a care home...
July 5, 2017: Clinical Gerontologist
https://www.readbyqxmd.com/read/28742129/treatment-outcomes-of-pre-surgical-infant-orthopedics-in-patients-with-non-syndromic-cleft-lip-and-or-palate-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#18
Hamid Reza Hosseini, Eleftherios G Kaklamanos, Athanasios E Athanasiou
BACKGROUND: Non-syndromic clefts lip and/or palate (CL/P) defects may have manifold significant and detrimental consequences for the affected individuals and their family environment. Although the use of pre-surgical infant orthopedics (PSIO) was introduced as a means to improve management and treatment outcomes, there still remains a controversy. OBJECTIVE: To investigate the effectiveness of PSIO in patients with non-syndromic CL/P and evaluate the quality of the available evidence...
2017: PloS One
https://www.readbyqxmd.com/read/28741757/equivalent-missense-variant-in-the-foxp2-and-foxp1-transcription-factors-causes-distinct-neurodevelopmental-disorders
#19
Elliot Sollis, Pelagia Deriziotis, Hirotomo Saitsu, Noriko Miyake, Naomichi Matsumoto, Mariette J V Hoffer, Claudia A L Ruivenkamp, Mariëlle Alders, Nobuhiko Okamoto, Emilia K Bijlsma, Astrid S Plomp, Simon E Fisher
The closely related paralogues FOXP2 and FOXP1 encode transcription factors with shared functions in the development of many tissues, including the brain. However, while mutations in FOXP2 lead to a speech/language disorder characterized by childhood apraxia of speech (CAS), the clinical profile of FOXP1 variants includes a broader neurodevelopmental phenotype with global developmental delay, intellectual disability and speech/language impairment. Using clinical whole-exome sequencing, we report an identical de novo missense FOXP1 variant identified in three unrelated patients...
July 25, 2017: Human Mutation
https://www.readbyqxmd.com/read/28739559/nurse-moderated-internet-based-support-for-new-mothers-non-inferiority-randomized-controlled-trial
#20
Michael G Sawyer, Christy E Reece, Kerrie Bowering, Debra Jeffs, Alyssa C P Sawyer, Murthy Mittinty, John W Lynch
BACKGROUND: Internet-based interventions moderated by community nurses have the potential to improve support offered to new mothers, many of whom now make extensive use of the Internet to obtain information about infant care. However, evidence from population-based randomized controlled trials is lacking. OBJECTIVE: The aim of this study was to test the non-inferiority of outcomes for mothers and infants who received a clinic-based postnatal health check plus nurse-moderated, Internet-based group support when infants were aged 1-7 months as compared with outcomes for those who received standard care consisting of postnatal home-based support provided by a community nurse...
July 24, 2017: Journal of Medical Internet Research
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