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https://www.readbyqxmd.com/read/28537937/dexmedetomidine-the-new-all-in-one-drug-in-paediatric-anaesthesia
#1
Cedric E Sottas, Brian J Anderson
PURPOSE OF REVIEW: Dexmedetomidine is a drug with sedative, anxiolytic, sympatholytic and analgesic properties, which is finding widespread practice in paediatric anaesthesia and related practices. The present review summarizes its pharmacology and current experience with the drug. RECENT FINDINGS: Dexmedetomidine is proving useful in many diverse areas in paediatric anaesthesia where its sedative properties are useful for premedication, fibreoptic intubation and radiologic procedures...
May 22, 2017: Current Opinion in Anaesthesiology
https://www.readbyqxmd.com/read/28535206/clinical-exome-sequencing-reports-current-informatics-practice-and-future-opportunities
#2
Rajeswari Swaminathan, Yungui Huang, Caroline Astbury, Sara Fitzgerald-Butt, Katherine Miller, Justin Cole, Christopher Bartlett, Simon Lin
The increased adoption of clinical whole exome sequencing (WES) has improved the diagnostic yield for patients with complex genetic conditions. However, the informatics practice for handling information contained in whole exome reports is still in its infancy, as evidenced by the lack of a common vocabulary within clinical sequencing reports generated across genetic laboratories. Genetic testing results are mostly transmitted using portable document format, which can make secondary analysis and data extraction challenging...
May 23, 2017: Journal of the American Medical Informatics Association: JAMIA
https://www.readbyqxmd.com/read/28533102/real-time-electronic-dashboard-technology-and-its-use-to-improve-pediatric-radiology-workflow
#3
REVIEW
Randheer Shailam, Ariel Botwin, Markus Stout, Michael S Gee
The purpose of our study was to create a real-time electronic dashboard in the pediatric radiology reading room providing a visual display of updated information regarding scheduled and in-progress radiology examinations that could help radiologists to improve clinical workflow and efficiency. To accomplish this, a script was set up to automatically send real-time HL7 messages from the radiology information system (Epic Systems, Verona, WI) to an Iguana Interface engine, with relevant data regarding examinations stored in an SQL Server database for visual display on the dashboard...
March 19, 2017: Current Problems in Diagnostic Radiology
https://www.readbyqxmd.com/read/28532210/the-linear-nonthreshold-lnt-model-as-used-in-radiation-protection-an-ncrp-update
#4
John D Boice
Purpose/Objective(s): The linear non-threshold (LNT) model has been used in radiation protection for over 40 years and has been hotly debated! It relies heavily on human epidemiology, with support from radiobiology. The scientific underpinnings include NCRP Report No. 136 ("Evaluation of the Linear-Nonthreshold Dose-Response Model for Ionizing Radiation"), UNSCEAR 2000, ICRP Publication 99 (2004) and the National Academies BEIR VII Report (NRC 2006). NCRP Scientific Committee 1-25 is reviewing recent epidemiologic studies focusing on dose-response models, including threshold, and the relevance to radiation protection...
May 23, 2017: International Journal of Radiation Biology
https://www.readbyqxmd.com/read/28527052/action-mechanisms-of-onabotulinum-toxin-a-hints-for-selection-of-eligible-patients
#5
Carlo Lovati, Luca Giani
In the past few decades, the so-feared botulinum toxin has conversely acquired the role of a ever more versatile therapeutic substance, used in an increasing number of pathological situations, including chronic headache and more precisely in the prophylaxis of chronic migraine. The medical use of botulinum toxin allowed to better understand its multiple mechanisms of action. Investigations about the pathophysiology of primary and secondary headaches has shown a series of common biological elements that frequently are also targets of the action of botulinum toxin...
May 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28526512/privacy-trainee-rights-and-accountability-in-radiology-education
#6
REVIEW
Cory M Pfeifer
RATIONALE AND OBJECTIVES: Academic radiologists commonly hold multiple simultaneous roles within the landscape of physician training. This paper analyzes theoretical scenarios describing relationships between medical students, residents, and physician educators in radiology. MATERIALS AND METHODS: The scenarios presented involve medical student supervision, radiology resident recruitment, and resident termination with respect to relevant ethical, regulatory, and legal considerations...
March 28, 2017: Academic Radiology
https://www.readbyqxmd.com/read/28523491/-practical-radiation-protection-of-the-patient-in-radiological-diagnostics
#7
REVIEW
M Fiebich
BACKGROUND: The use of radiation protection equipment can reduce the radiation exposure of patients. OBJECTIVES: The aim was to show which patient shields should be used for the different types of examination. METHODS: The results of multiple studies were compiled and analyzed and recommendations made for the use of patient shields. The absolute dose values and the protective effect were considered. RESULTS: Radiological protection should be used in many investigations; particularly in the case of CT investigations, a reasonable dose reduction potential exists due to the higher radiation dose...
May 18, 2017: Der Radiologe
https://www.readbyqxmd.com/read/28522667/baseline-survey-of-the-neuroradiology-work-environment-in-the-united-states-with-reported-trends-in-clinical-work-nonclinical-work-perceptions-of-trainees-and-burnout-metrics
#8
J Y Chen, F J Lexa
BACKGROUND AND PURPOSE: Neuroradiologists have faced continuously increasing clinical workloads. Our aim was to establish and report a baseline survey of the current neuroradiology work environment in the United States and of experiential changes in recent years. MATERIALS AND METHODS: A voluntary survey was sent to practicing and out-of-training members of the American Society of Neuroradiology in the United States. Selected measures included workday volume and length, burnout symptoms, participation in academic and practice-building duties; effects on perceived interpretation quality, communication of abnormal results, and consideration of early retirement or career changes, among others...
May 18, 2017: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/28516963/the-endoscopic-evaluation-of-the-oral-phase-of-swallowing-oral-fees-o-fees-a-pilot-study-of-the-clinical-use-of-a-new-procedure
#9
D Farneti, B Fattori, L Bastiani
Oral FEES (O-FEES) is an endoscopic procedure conceived to directly visualise the oral phase of swallowing. In the perspective of clinical use, the feasibility, safety and acceptability of O-FEES has been evaluated. Subsequently, the procedure was compared with the radiological gold standard. The acceptability of O-FEES was compared to that of FEES using a 10 point questionnaire submitted to a sample of 52 outpatients complaining of swallowing disorders. Repeated measure analysis of variance (rm-ANOVA) models were used to test the mean difference of acceptability in the same subjects after FEES and O-FEES...
June 2017: Acta Otorhinolaryngologica Italica
https://www.readbyqxmd.com/read/28515591/the-current-status-of-pediatric-radiology-in-india-a-conference-based-survey
#10
Jacob Therakathu, Vikas K Yadav, Shyamkumar N Keshava, Sridhar Gibikote, Govind B Chavan, Manohar Shroff
INTRODUCTION: Like most other developing countries, India has a large proportion of children among its population. However, the facilities for adequate treatment of this large population is inadequate. The development of pediatric radiology as a subspecialty is still at an infant stage in India. The goal of our study was to assess the awareness about the current status of pediatric radiology in India. MATERIALS AND METHODS: A questionnaire was handed over to all attendees of a pediatric radiology conference to assess their opinion regarding the adequacy of pediatric training and practice in India...
January 2017: Indian Journal of Radiology & Imaging
https://www.readbyqxmd.com/read/28515041/multidisciplinary-evaluation-of-interstitial-lung-diseases-current-insights-number-1-in-the-series-radiology-edited-by-nicola-sverzellati-and-sujal-desai
#11
Simon L F Walsh
Multidisciplinary team (MDT) diagnosis is regarded as the diagnostic reference standard for interstitial lung disease (ILD). Several studies have reported that MDT diagnosis is associated with higher levels of diagnostic confidence and better interobserver agreement when compared to the individual components of the MDT in isolation. Although this recommendation is widely accepted, no guideline statement specifies what constitutes an MDT meeting and how its participants should govern it. Furthermore, the precise role of an MDT meeting in the setting of ILD may vary from one group to another...
June 30, 2017: European Respiratory Review: An Official Journal of the European Respiratory Society
https://www.readbyqxmd.com/read/28514641/mapping-workforce-configuration-and-operational-models-in-australian-emergency-departments-a-national-survey
#12
Glenn Gardner, Anne Gardner, Sandy Middleton, Julie Considine, Gerard Fitzgerald, Luke Christofis, Anna Doubrovsky, Margaret Adams, Jane O'Connell
Objective Hospital emergency departments (ED) in Australia and internationally have been experiencing increased demand, resulting in reduced hospital quality, impaired access and adverse health outcomes. Effective evaluation of new ED service models and their effect on outcomes is reliant on baseline measures of the staffing configuration and organisational characteristics of the EDs being studied. The aim of the present study was to comprehensively measure these variables in Australian EDs.Methods Australian hospital EDs with 24-h medical and nursing cover were identified and invited to participate in the study...
May 18, 2017: Australian Health Review: a Publication of the Australian Hospital Association
https://www.readbyqxmd.com/read/28514219/science-to-practice-killing-dormant-cells-is-targeting-autophagy-the-key-to-complete-tumor-response-in-transarterial-chemoembolization
#13
Lynn Jeanette Savic, Julius Chapiro, Jean-François Geschwind
In this issue of Radiology, Gade et al ( 1 ) describe a unique mechanism of hepatocellular carcinoma (HCC) cells for surviving ischemia induced by transarterial embolization (TAE)/transarterial chemoembolization (TACE) in a state of cell cycle arrest-a function that may serve as a defensive shield against conventional chemotherapeutic agents. This finding adds to our knowledge and establishes a previously poorly understood mechanism of chemoresistance in HCC. As the Achilles heel in terms of this process, a concurrent upregulation of autophagic flux as an adaptive response to TAE-like ischemia was found by the authors...
June 2017: Radiology
https://www.readbyqxmd.com/read/28510805/interventional-radiology-in-iatrogenic-ureteral-leaks-case-series-and-literature-review
#14
Claudia Trombatore, Giuseppe Giordano, Vincenzo Magnano San Lio
Iatrogenic ureteral injuries are a dramatic complication in medical practice. Nowadays there are no universal guidelines for their management. The aim of our study was to evaluate the feasibility of the percutaneous treatment in restoring ureteral integrity in 19 patients that came to our attention. In each case retrograde stenting failed and patients were candidates for re-surgery. Our strategy consists of two phases. The first step is the nephrostomy that allows an external urinary diversion putting dry the damaged ureteral segment...
May 16, 2017: La Radiologia Medica
https://www.readbyqxmd.com/read/28508184/nationwide-cross-sectional-adherence-to-mammography-screening-guidelines-national-behavioral-risk-factor-surveillance-system-survey-results
#15
Anand Narayan, Alexander Fischer, Zihe Zhang, Ryan Woods, Elizabeth Morris, Susan Harvey
PURPOSE: Varying recommendations about breast cancer screening have generated much confusion about when and how often to undergo mammography screening, yet there is limited population-based data about the extent to which patients adhere to various mammographic screening guidelines in practice. Our purpose was to evaluate population-based adherence to mammographic screening using criteria from major guideline-producing organizations. METHODS: Women aged 40-74 in the 2014 Behavioral Risk Factor Surveillance System survey were included...
May 15, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28506452/performing-nuclear-medicine-examinations-in-pregnant-women
#16
REVIEW
Paolo Zanotti-Fregonara, Elif Hindie
The number of nuclear medicine examinations performed worldwide has been steadily increasing over the last few years. By consequence, an ever increasing number of pregnant women are likely to be exposed to radioisotopes. The range of doses encountered in nuclear medicine practice is well below the threshold for deterministic effects, such as embryonic death, birth defects or mental retardation. According to the linear no-threshold hypothesis, however, stochastic effects (e.g. an increased risk of cancer) remain possible even at this dose range...
May 11, 2017: Physica Medica: PM
https://www.readbyqxmd.com/read/28505478/dose-assessment-in-environmental-radiological-protection-state-of-the-art-and-perspectives
#17
REVIEW
Karolina Stark, José M Goméz-Ros, Jordi Vives I Batlle, Elisabeth Lindbo Hansen, Karine Beaugelin-Seiller, Lawrence A Kapustka, Michael D Wood, Clare Bradshaw, Almudena Real, Corynne McGuire, Thomas G Hinton
Exposure to radiation is a potential hazard to humans and the environment. The Fukushima accident reminded the world of the importance of a reliable risk management system that incorporates the dose received from radiation exposures. The dose to humans from exposure to radiation can be quantified using a well-defined system; its environmental equivalent, however, is still in a developmental state. Additionally, the results of several papers published over the last decade have been criticized because of poor dosimetry...
May 12, 2017: Journal of Environmental Radioactivity
https://www.readbyqxmd.com/read/28504572/screening-mammography-for-women-in-their-40s-the-potential-impact-of-the-american-cancer-society-and-u-s-preventive-services-task-force-breast-cancer-screening-recommendations
#18
Jenifer A Pitman, Geraldine B McGinty, Rohan R Soman, Michele B Drotman, Melissa B Reichman, Elizabeth Kagan Arleo
OBJECTIVE: The purpose of this study was to review screening mammograms obtained in one practice with the primary endpoint of determining the rate of detection of breast cancer and associated prognostic features in women 40-44 and 45-49 years old. MATERIALS AND METHODS: The retrospective cohort study included women in their 40s with breast cancer detected at screening from June 2014 through May 2016. The focus was on cancer detection rate, pathologic findings, and risk factors...
May 15, 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28503293/historical-influence-on-the-practice-of-chiropractic-radiology-part-ii-thematic-analysis-on-the-opinions-of-diplomates-of-the-american-chiropractic-college-of-radiology-about-the-future
#19
Kenneth J Young
BACKGROUND: Over the past 20 years, various authors have addressed the question of the future of chiropractic. Most were positive about the future, with some advocating evidence-based practice and integration with mainstream healthcare, some advocating continued separation with an emphasis on subluxation-based care or the traditional/historical paradigm of chiropractic, and some calling for tolerance and unity. No papers were found specifically inquiring about the future of chiropractic radiology...
2017: Chiropractic & Manual Therapies
https://www.readbyqxmd.com/read/28503292/historical-influence-on-the-practice-of-chiropractic-radiology-part-i-a-survey-of-diplomates-of-the-american-chiropractic-college-of-radiology
#20
Kenneth J Young
BACKGROUND: It is known that not all chiropractors follow mainstream guidelines on the use of diagnostic ionising radiation. Various reasons have been discussed in the literature, including using radiography to screen for congenital anomalies, to perform postural analysis, to search for contraindications to spinal manipulation, and to document chiropractic subluxations, i.e., tiny anatomical displacements of vertebrae thought to affect nerves and health. The visualisation of subluxations was the reason chiropractic first adopted the x-ray in 1910...
2017: Chiropractic & Manual Therapies
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