keyword
MENU ▼
Read by QxMD icon Read
search

Cart

keyword
https://www.readbyqxmd.com/read/28343024/sex-estimation-with-the-total-area-of-the-proximal-femur-a-densitometric-approach
#1
Francisco Curate, Anabela Albuquerque, Izilda Ferreira, Eugénia Cunha
The estimation of sex is a central step to establish the biological profile of an anonymous skeletal individual. Imaging techniques, including bone densitometry, have been used to evaluate sex in remains incompletely skeletonized. In this paper, we present a technique for sex estimation using the total area (TA) of the proximal femur, a two-dimensional areal measurement determined through densitometry. TA was acquired from a training sample (112 females; 112 males) from the Coimbra Identified Skeletal Collection (University of Coimbra, Portugal)...
March 8, 2017: Forensic Science International
https://www.readbyqxmd.com/read/28335737/cytomegalovirus-infection-in-hiv-infected-versus-non-infected-infants-and-hiv-disease-progression-in-cytomegalovirus-infected-versus-non-infected-infants-early-treated-with-cart-in-the-anrs-12140-pediacam-study-in-cameroon
#2
Anfumbom K W Kfutwah, Paul Alain T Ngoupo, Casimir Ledoux Sofeu, Francis Ateba Ndongo, Georgette Guemkam, Suzie Tetang Ndiang, Félicité Owona, Ida Calixte Penda, Patrice Tchendjou, Christine Rouzioux, Josiane Warszawski, Albert Faye, Mathurin Cyrille Tejiokem
BACKGROUND: The outcome of CMV/HIV co-infection in infants treated early with combined antiretroviral therapy (cART) in resource-limited settings has not been described. We aimed to estimate the prevalence and identify factors associated with early CMV infection in HIV-infected and non-infected infants included in a study in Cameroon, and to compare HIV disease progression and survival after 1 year of early cART, following infants' CMV status. METHODS: HIV-infected infants followed from birth or from HIV diagnosis before 7 months old and HIV-uninfected infants born to HIV-infected or uninfected mothers were tested for CMV at a median age of 4...
March 23, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28327462/neurocognitive-dysfunction-in-hiv-infected-youth-investigating-the-relationship-with-immune-activation
#3
Allison Ross Eckard, Julia C Rosebush, Mary Ann O'Riordan, Chanda C Graves, Ashley Alexander, Anita K Grover, S Thera Lee, Jakob G Habib, Joshua H Ruff, Ann Chahroudi, Grace A McComsey
BACKGROUND: HIV-infected individuals are at increased risk of neurocognitive impairment compared to the general population. Studies suggest that, despite combination antiretroviral therapy (cART), HIV infection causes immune activation which results in neural damage; however, few data exist in HIV-infected youth. METHODS: HIV-infected youth 8-26 years old on cART with virologic suppression were prospectively enrolled along with healthy controls. Neurocognitive performance was assessed by age-appropriate Wechsler Intelligence Scales...
March 22, 2017: Antiviral Therapy
https://www.readbyqxmd.com/read/28325171/pregnancy-and-neonatal-outcomes-among-a-cohort-of-hiv-infected-women-in-a-large-italian-teaching-hospital-a-30-year-retrospective-study
#4
S Grignolo, R Agnello, D Gerbaldo, C Gotta, C Alicino, F Del Puente, L Taramasso, B Bruzzone, C Gustavino, S Trasino, A DE Maria, G Icardi, C Viscoli, A DI Biagio
The primary study objective was to investigate three decades from 1985 to 2014 of changes in pregnancies among HIV-infected women. The secondary objective was to assess risk factors associated with preterm delivery and severe small-for-gestational-age (SGA) infants in HIV-infected women. A retrospective review of deliveries among pregnant HIV-infected women at the University of Genoa and IRCCS San Martino-IST in Genoa between 1985 and 2014 was performed. Univariate and multivariable analyses were used to study the variables associated with neonatal outcomes...
March 22, 2017: Epidemiology and Infection
https://www.readbyqxmd.com/read/28320569/a-new-method-to-predict-hospital-mortality-in-severe-community-acquired-pneumonia
#5
Xin Wang, Jianlong Jiao, Rongwei Wei, Yongli Feng, Xiuqin Ma, Yuan Li, Yue Du
BACKGROUND & AIMS: The aim of this study is to develop a new method that is able to accurately predict the 28day hospital mortality in patients with severe community acquired pneumonia (SCAP) at an early stage. METHODS: We selected 37,348 SCAP patients in ICU from 173 hospitals during 2011.1-2013.12. The predictive factors for 28day hospital mortality were evaluated retrospectively. All cases underwent intensive care, blood routine, blood biochemical tests and arterial blood gas analysis...
March 17, 2017: European Journal of Internal Medicine
https://www.readbyqxmd.com/read/28319476/anesthesia-in-patients-with-infectious-disease-caused-by-multi-drug-resistant-bacteria
#6
Sharon Einav, Yonit Wiener-Well
PURPOSE OF REVIEW: Up to 50% of specific bacterial strains in healthcare admission facilities are multidrug-resistant organisms (MDROs). Involvement of anesthesiologists in management of patients carrying/at risk of carrying MDROs may decrease transmission in the Operating Room (OR). RECENT FINDINGS: Anesthesiologists, their work area and tools have all been implicated in MDRO outbreaks. Causes include contamination of external ventilation circuits and noncontribution of filters to prevention, inappropriate decontamination procedures for nondisposable equipment (e...
March 17, 2017: Current Opinion in Anaesthesiology
https://www.readbyqxmd.com/read/28319324/future-of-robotic-surgery-in-urology
#7
Jens J Rassweiler, Riccardo Autorino, Jan Klein, Alex Mottrie, Ali Serdar Goezen, Jens-Uwe Stolzenburg, Koon H Rha, Marc Schurr, Jihad Kaouk, Vipul Patel, Prokar Dasgupta, Evangelos Liatsikos
OBJECTIVES: To provide a comprehensive overview of the current status and future perspectives in the field of robotic systems for urologic surgery. MATERIALS AND METHODS: A non-systematic literature review was performed by using PubMed / Medline search electronic engines. Existing patents for robotic devices were researched using the Google search machine. Findings were critically analyzed also by taking into account personal experience of the authors. RESULTS: Relevant patents of the first generation of the da Vinci platform will expire in 2019...
March 20, 2017: BJU International
https://www.readbyqxmd.com/read/28314964/increased-intake-of-energy-dense-diet-and-negative-energy-balance-in-a-mouse-model-of-chronic-psychosocial-defeat
#8
Roberto Coccurello, Adele Romano, Giacomo Giacovazzo, Bianca Tempesta, Marco Fiore, Anna Maria Giudetti, Ilaria Marrocco, Fabio Altieri, Anna Moles, Silvana Gaetani
PURPOSE: Chronic exposure to stress may represent a risk factor for developing metabolic and eating disorders, mostly driven by the overconsumption of easily accessible energy-dense palatable food, although the mechanisms involved remain still unclear. In this study, we used an ethologically oriented murine model of chronic stress caused by chronic psychosocial defeat (CPD) to investigate the effects of unrestricted access to a palatable high fat diet (HFD) on food intake, body weight, energy homeostasis, and expression of different brain neuropeptides...
March 17, 2017: European Journal of Nutrition
https://www.readbyqxmd.com/read/28303692/combined-radial-tibial-access-strategy-and-radial-tibial-reverse-cart-in-a-patient-with-aortobifemoral-graft-and-complex-superficial-femoral-artery-occlusion
#9
Elias B Hanna, Davey L Prout
We present the case of a patient with a history of aortobifemoral grafting who presented with left lower extremity ischemic rest pain. Aortofemoral angiography was performed through a left radial access and showed a long, calcified total occlusion of the left superficial femoral artery (SFA) and a subtotal popliteal occlusion. The popliteal artery and SFA were crossed retrogradely through a 4-Fr anterior tibial access; the retrograde devices went subintimally and did not reenter at the common femoral level...
March 17, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28302596/estimating-accuracy-at-exercise-intensities-a-comparative-study-of-self-monitoring-heart-rate-and-physical-activity-wearable-devices
#10
Erin E Dooley, Natalie M Golaszewski, John B Bartholomew
BACKGROUND: Physical activity tracking wearable devices have emerged as an increasingly popular method for consumers to assess their daily activity and calories expended. However, whether these wearable devices are valid at different levels of exercise intensity is unknown. OBJECTIVE: The objective of this study was to examine heart rate (HR) and energy expenditure (EE) validity of 3 popular wrist-worn activity monitors at different exercise intensities. METHODS: A total of 62 participants (females: 58%, 36/62; nonwhite: 47% [13/62 Hispanic, 8/62 Asian, 7/62 black/ African American, 1/62 other]) wore the Apple Watch, Fitbit Charge HR, and Garmin Forerunner 225...
March 16, 2017: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/28302065/lamivudine-dolutegravir-dual-therapy-in-hiv-infected-virologically-suppressed-patients
#11
Franco Maggiolo, Roberto Gulminetti, Layla Pagnucco, Margherita Digaetano, Simone Benatti, Daniela Valenti, Annapaola Callegaro, Diego Ripamonti, Cristina Mussini
BACKGROUND: Little is known about the applicability of dual treatments based on integrase inhibitors. We explored the combination of lamivudine + dolutegravir as an option when switching from standard cART in virologically suppressed patients. METHODS: In this prospective cohort we enrolled patients previously switched to 3TC + DTG who were 18 years or older, with no previous resistance mutations to the used drugs, having a HIV-RNA <50 copies/ml for 6 months or longer, negative for HBsAg and on a stable (>6 months) cART...
March 16, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28302019/the-breakthroughs-in-cancer-immune-checkpoint-based-therapy-a-review-of-development-in-immune-checkpoint-study-and-its-application
#12
Yao Huang, Dong Liang, Jingfeng Liu, Jinhua Zeng, Yongyi Zeng
Recently, immunotherapy has attracted more attentions to fight cancer due to its selectivity, long lasting effects, and demonstrated better overall survival and tolerance, when compared to patients treated with conventional chemotherapy or radiotherapy alone. The anti-tumor response of patient with cancer is improved either by increasing the effector cell number, the production of soluble mediators, or by modulating the host's immune checkpoint. Over the last decades, many new approaches in immunotherapy have been developed, such as immune checkpoint inhibitors, chimeric antigen receptor T cells (CART), specific T-cell -receptor T cells (TCRT) and cancer vaccine, some of which has been approved by FDA to treat several cancer types...
March 15, 2017: Combinatorial Chemistry & High Throughput Screening
https://www.readbyqxmd.com/read/28300671/the-effect-of-cart-on-pituitary-hormones-release-from-cultured-pituitary-cells-harvested-from-fasted-and-fed-ad-libitum-male-rats
#13
M Chmielowska, B Baranowska, E Wolinska-Witort, L Martynska, M Kalisz, A Litwiniuk, W Bik
Cocaine and Amphetamine-Regulated Transcript (CART) is widely expressed in the central nervous system and in several endocrine organs. CART is an important factor in the regulation of energy homeostasis. The aim of the study was to assess the role of CART in physiological response of pituitary cells in a course of starvation. The pituitary cells harvested from starved and fed ad libitum male rats were cultured for 48h and treated with: 0.1nM, 1nM, 10nM or 100nM doses of CART. The medium was collected after 60min and stored at -70°C until samples were further assayed for: LH, FSH, PRL, GH, TSH and ACTH...
March 11, 2017: Peptides
https://www.readbyqxmd.com/read/28298195/role-of-systemic-inflammation-scores-for-prediction-of-clinical-outcomes-in-patients-treated-with-atazanavir-not-boosted-by-ritonavir-in-the-italian-master-cohort
#14
Maria Concetta Postorino, Mattia Prosperi, Emanuele Focà, Eugenia Quiros-Roldan, Elisa Di Filippo, Franco Maggiolo, Alberto Borghetti, Nicoletta Ladisa, Massimo Di Pietro, Andrea Gori, Laura Sighinolfi, Angelo Pan, Nicola Mazzini, Carlo Torti
BACKGROUND: Atazanavir (ATV) not boosted by ritonavir (uATV) has been frequently used in the past for switching combination antiretroviral therapy (cART). However, the clinical outcomes and predictors of such strategy are unknown. METHODS: An observational study was carried out on the Italian MASTER, selecting HIV infected patients on cART switching to an uATV-containing regimen. Baseline was set as the last visit before uATV initiation. In the primary analysis, a composite clinical end-point was defined as the first occurring of any condition among: liver, cardiovascular, kidney, diabetes, non AIDS related cancer or death events...
March 15, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28296911/longitudinal-dynamics-of-the-hiv-specific-b-cell-response-during-intermittent-treatment-of-primary-hiv-infection
#15
Godelieve J de Bree, Adam K Wheatley, Rebecca M Lynch, Madhu Prabhakaran, Marlous L Grijsen, Jan M Prins, Stephen D Schmidt, Richard A Koup, John R Mascola, Adrian B McDermott
BACKGROUND: Neutralizing antibodies develop in natural HIV-1 infection. Their development often takes several years and may rely on chronic virus exposure. At the same time recent studies show that treatment early in infection may provide opportunities for immune preservation. However, it is unknown how intermittent treatment in early infection affects development of the humoral immune response over time. We investigate the effect of cART in early HIV infection on the properties of the memory B cell compartment following 6 months of cART or in the absence of treatment...
2017: PloS One
https://www.readbyqxmd.com/read/28293774/hiv-associated-neurodegeneration-and-neuroimmunity-multivoxel-mr-spectroscopy-study-in-drug-na%C3%A3-ve-and-treated-patients
#16
Jasmina Boban, Dusko Kozic, Vesna Turkulov, Jelena Ostojic, Robert Semnic, Dajana Lendak, Snezana Brkic
OBJECTIVES: The aim of this study was to test neurobiochemical changes in normal appearing brain tissue in HIV+ patients receiving and not receiving combined antiretroviral therapy (cART) and healthy controls, using multivoxel MR spectroscopy (mvMRS). METHODS: We performed long- and short-echo 3D mvMRS in 110 neuroasymptomatic subjects (32 HIV+ subjects on cART, 28 HIV+ therapy-naïve subjects and 50 healthy controls) on a 3T MR scanner, targeting frontal and parietal supracallosal subcortical and deep white matter and cingulate gyrus (NAA/Cr, Cho/Cr and mI/Cr ratios were analysed)...
March 14, 2017: European Radiology
https://www.readbyqxmd.com/read/28290053/targeting-cancer-stem-cells-by-using-chimeric-antigen-receptor-modified-t-cells-a-potential-and-curable-approach-for-cancer-treatment
#17
REVIEW
Yelei Guo, Kaichao Feng, Yao Wang, Weidong Han
Cancer stem cells (CSCs), a subpopulation of tumor cells, have self-renewal and multi-lineage differentiation abilities that play an important role in cancer initiation, maintenance, and metastasis. An accumulation of evidence indicates that CSCs can cause conventional therapy failure and cancer recurrence because of their treatment resistance and self-regeneration characteristics. Therefore, approaches that specifically and efficiently eliminate CSCs to achieve a durable clinical response are urgently needed...
March 13, 2017: Protein & Cell
https://www.readbyqxmd.com/read/28287204/-biliary-and-kidney-lithiasis-during-treatment-with-daclatasvir-sofosbuvir-ribavirin-and-atazanavir-ritonavir-abacavir-lamivudine-in-an-hiv-hcv-genotype-4-infected-patient-a-case-report
#18
Andrea Vavassori, Paola Lanza, Ilaria Izzo, Salvatore Casari, Silvia Odolini, Serena Zaltron, Elena Festa, Francesco Castelli
New Direct-acting Antiviral Agents (DAA)-based anti-HCV therapies currently provide extraordinary opportunities to cure patients. Drug-drug interactions are however a real challenge during treatment. In particular, in HIV-infected patients in cART, DAA choice is limited by such interactions, which can result both in reduced efficacy and toxicity. We report the case of a HIV-infected patient on cART with atazanavir/ritonavir/abacavir/lamivudine, who presented kidney and biliary lithiasis, the latter treated with endoscopic retrograde cholangiopancreatography and endoscopic biliary sphincterotomy, after beginning anti-HCV treatment with daclatasvir/sofosbuvir/ribavirin...
February 2017: Recenti Progressi in Medicina
https://www.readbyqxmd.com/read/28284222/teriflunomide-and-monomethylfumarate-target-hiv-induced-neuroinflammation-and-neurotoxicity
#19
Björn Ambrosius, Simon Faissner, Kirsten Guse, Marec von Lehe, Thomas Grunwald, Ralf Gold, Bastian Grewe, Andrew Chan
HIV-associated neurocognitive disorders (HAND) affect about 50% of infected patients despite combined antiretroviral therapy (cART). Ongoing compartmentalized inflammation mediated by microglia which are activated by HIV-infected monocytes has been postulated to contribute to neurotoxicity independent from viral replication. Here, we investigated effects of teriflunomide and monomethylfumarate on monocyte/microglial activation and neurotoxicity. Human monocytoid cells (U937) transduced with a minimal HIV-Vector were co-cultured with human microglial cells (HMC3)...
March 11, 2017: Journal of Neuroinflammation
https://www.readbyqxmd.com/read/28282247/effect-of-tenofovir-disoproxil-fumarate-on-incidence-of-chronic-kidney-disease-and-rate-of-estimated-glomerular-filtration-rate-decrement-in-hiv-1-infected-treatment-na%C3%A3-ve-asian-patients-results-from-12-year-observational-cohort
#20
Soichiro Suzuki, Takeshi Nishijima, Yohei Kawasaki, Takuma Kurosawa, Yoshikazu Mutoh, Yoshimi Kikuchi, Hiroyuki Gatanaga, Shinichi Oka
Little evidence is available for the incidence of chronic kidney disease (CKD) and rate of estimated glomerular filtration rate (eGFR) decrement among Asians with low body weight who are susceptible to tenofovir disoproxil fumarate (TDF) nephrotoxicity. In this 12-year observational cohort in Tokyo, we examined 1383 treatment-naïve HIV-1-infected Asians [720 started TDF-containing (TDF group) and 663 started non-TDF-containing (control) combination antiretroviral therapy (cART)]. The CKD incidence was calculated, and the effect of TDF use on CKD development was estimated using logistic regression...
March 2017: AIDS Patient Care and STDs
keyword
keyword
20241
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"