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Stroke prognosis

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https://www.readbyqxmd.com/read/27905390/-pr%C3%B0-gnosis-of-motor-function-recovery-in-ischemic-stroke-using-diffusion-tensor-mri
#1
M Yu Maksimova, T A Popova, R N Konovalov
AIM: To identify factors of motor recovery in ischemic stroke (IS) using diffusion tensor imaging (DTI). MATERIAL AND METHODS: Forty-seven patients with IS were studied within 1-2, 7-8, 14-15, 20-21 days after stroke. The fractional anisotropy (FA) values of the pyramidal tract were measured in the posterior limb of the internal capsule, cerebral peduncle and pons. Relative values of FA (rFA) ratio (rFA=FA affected side/FA unaffected side) were assessed as well...
2016: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://www.readbyqxmd.com/read/27904159/copeptin-as-a-biomarker-for-prediction-of-prognosis-of-acute-ischemic-stroke-and-transient-ischemic-attack-a-meta-analysis
#2
Qian Xu, Yunfan Tian, Hao Peng, Hongmei Li
This meta-analysis aimed to investigate the predictive effect of copeptin as a biomarker for the prognosis of acute ischemic stroke and transient ischemic attack. Electronic databases including PubMed, Medline, EMBASE, Web of Science and Cochrane Central were searched for studies assessing the association of copeptin level on admission with prognosis of acute ischemic stroke and transient ischemic attack. The Newcastle-Ottawa Quality assessment scale for cohort study was used to evaluate quality. A total of 1976 acute ischemic stroke patients from 6 studies were included, and 59% of patients were male...
December 1, 2016: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://www.readbyqxmd.com/read/27903337/-risk-factors-for-perioperative-stroke-in-aged-patients-undergoing-nonneurologic-and-noncardiovascular-surgery
#3
B L Jiang, L Yao, Y Feng, J H Liu
Objective: To assess the incidence, risk factors, and outcomes of perioperative stroke in aged patients undergoing nonneurologic and noncardiovascular surgery. Methods: A total of 21 419 in-patients who were older than 65 years undergoing nonneurologic and noncardiovascular surgery in Peking University People's Hospital from January 2010 to May 2016 were retrospectively recruited in this study.The patients were divided into two groups: patients with perioperative stroke were allocated in stroke group, and the other patients were in the non-stroke group...
November 22, 2016: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/27901117/sex-specific-association-between-uric-acid-and-outcomes-after-acute-ischemic-stroke-a-prospective-study-from-catis-trial
#4
Li-Hua Chen, Chongke Zhong, Tan Xu, Tian Xu, Yanbo Peng, Aili Wang, Jinchao Wang, Hao Peng, Qunwei Li, Zhong Ju, Deqin Geng, Jintao Zhang, Yongqiu Li, Yonghong Zhang, Jiang He
The relationship between serum uric acid (UA) and outcomes after acute ischemic stroke remains debatable in human studies, and the sex effect on this association has yet to be explored. Here, we investigated these associations in a prospective study from the China Antihypertensive Trial in Acute Ischemic Stroke. Baseline UA levels were measured in 3284 acute ischemic stroke patients. Primary outcome was defined as a combination of death and major disability (modified Rankin Scale score ≥3) at 3 months. UA levels were significantly higher in men than women (310...
November 30, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27899755/association-of-oxidized-low-density-lipoprotein-with-prognosis-of-stroke-and-stroke-subtypes
#5
Anxin Wang, Yuling Yang, Zhaoping Su, Wei Yue, Hongjun Hao, Lijie Ren, Yongjun Wang, Yibin Cao, Yilong Wang
BACKGROUND AND PURPOSE: The association between oxidized low-density lipoprotein (oxLDL) and the long-term prognosis of stroke is unclear. The aim of this study is to investigate whether oxLDL levels contribute to the prognosis of stroke and stroke subtypes. METHODS: All patients with ischemic stroke were recruited from the SOS-Stroke (Study of Oxidative Stress in Patients With Acute Ischemic Stroke) and classified into 5 different subtypes, according to the TOAST criteria (Trial of Org 10172 in Acute Stroke Treatment)...
November 29, 2016: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/27896904/contrast-induced-encephalopathy-following-cardiac-catheterization
#6
Roberto Spina, Neil Simon, Romesh Markus, David Wm Muller, Krishna Kathir
OBJECTIVES: To describe the epidemiology, pathophysiology, clinical presentation, and management of contrast-induced encephalopathy (CIE) following cardiac catheterization. BACKGROUND: CIE is an acute, reversible neurological disturbance directly attributable to the intra-arterial administration of iodinated contrast medium. METHODS: The PubMed database was searched and all cases in the literature were retrieved and reviewed. RESULTS: 52 reports of CIE following cardiac catheterization were found...
November 29, 2016: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/27896146/determination-of-functional-prognosis-in-hospitalized-patients-following-an-intensive-care-admission
#7
Natália A Ferreira, Agnaldo José Lopes, Arthur S Ferreira, George Ntoumenopoulos, Jerffesson Dias, Fernando S Guimaraes
AIM: To investigate the factors associated with the functional progress of hospitalized patients following an intensive care admission. METHODS: Retrospective study including data from a cohort of 198 hospitalized patients following an intensive care admission and not requiring mechanical ventilation in a single tertiary referral hospital. A generalized linear model was used to identify the main effects of clinical and demographic variables on the outcomes of functionality (KATZ Index of Independence in Activities of Daily Living) and muscle strength (MRC Scale)...
November 4, 2016: World Journal of Critical Care Medicine
https://www.readbyqxmd.com/read/27891240/differences-in-the-clinical-manifestations-and-short-term-prognosis-of-acute-cerebral-infarction-after-exposure-to-agent-orange
#8
SangWoo Han, Inha Hwang, Seung Min Kim, Young Soon Yang, SangWon Ha, Jeong Ho Han, Tae Hwan Park
BACKGROUND: Agent Orange (AO) is the code name for one of the herbicides and defoliants used in the Vietnam War. Studies conducted thus far show a significant correlation between AO and the occurrence of cardiovascular diseases. But there is little data on the association between AO and stroke, and limited studies have targeted patient groups exposed to AO. METHOD: Bohun medical center Institutional Review Board (IRB) approved the study. (ID: 341) We studied patients with acute ischemic stroke within 7 days of onset in VHS medical center and 4 other general hospitals...
2016: Annals of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/27890440/three-month-outcomes-are-poor-in-stroke-patients-with-cancer-despite-acute-stroke-treatment
#9
Shawna Cutting, Meagan Wettengel, James J Conners, Bichun Ouyang, Katharina Busl
INTRODUCTION: Stroke risk is increased in cancer patients. Prognosis in these patients is poor, with higher in-hospital mortality and increased subsequent mortality. However, data on stroke in cancer patients are limited, specifically regarding acute stroke treatment and functional outcomes. We aim to determine the functional outcomes of cancer patients admitted with acute stroke. MATERIALS AND METHODS: We retrospectively reviewed patients carrying a diagnosis of cancer who were admitted with acute ischemic stroke between March 2013 and February 2016...
November 24, 2016: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/27889950/retinopathy-a-sign-of-cerebral-small-vessel-disease-in-diabetes
#10
Toshitaka Umemura, Takahiko Kawamura
Cardio-cerebrovascular disease greatly influences the prognosis of diabetic patients. Silent lacunar infarcts, white matter lesions (WMLs), and cerebral microbleeds are magnetic resonance imaging (MRI) markers of cerebral small vessel disease (SVD) and as they are associated with stroke and dementia, prevention of their incidence and progression is important in clinical practice. The findings of previous autopsy and clinical studies suggest that lacunar infarcts are more prevalent in diabetic patients. On the other hand, the findings of studies on an association between diabetes and WMLs have been inconsistent...
November 27, 2016: Journal of Diabetes Investigation
https://www.readbyqxmd.com/read/27883210/rationale-and-design-of-the-bayes-interatrial-block-and-yearly-events-registry
#11
Manuel Martínez-Sellés, Adrian Baranchuk, Roberto Elosua, Antonio Bayés de Luna
The prevalence of interatrial block (IAB) is high in the elderly, particularly in those with heart disease. Despite this high prevalence-and the association of IAB with the risk of atrial fibrillation (AF), stroke, and cognitive decline-little information exists about the prognosis of older patients with IAB. P-wave duration and morphology are associated with risk of developing AF, stroke, and cognitive decline in elderly patients with structural heart disease. The aim of the Interatrial Block and Yearly Events (BAYES) registry is to assess the impact of IAB on the risk of AF and stroke during 3 years of follow-up...
November 24, 2016: Clinical Cardiology
https://www.readbyqxmd.com/read/27881850/relationship-between-asymptomatic-intra-cranial-lesions-and-brachial-ankle-pulse-wave-velocity-in-coronary-artery-disease-patients-without-stroke
#12
Noriaki Tabata, Daisuke Sueta, Takayoshi Yamashita, Daisuke Utsunomiya, Yuichiro Arima, Eiichiro Yamamoto, Kenichi Tsujita, Sunao Kojima, Koichi Kaikita, Seiji Hokimoto
Little is known about the significance of asymptomatic intra-cranial lesions (ICL) identified by brain MRI in coronary artery disease (CAD) patients. Silent cerebral lesions are suggested to be associated with arterial stiffness in healthy subjects. We investigated whether subclinical ICL are associated with arterial stiffness and the prognosis in CAD patients without medical history of cerebrovascular diseases. We recruited CAD patients who required percutaneous coronary intervention (PCI), did not meet exclusion criteria, and agreed with MRI before PCI...
November 24, 2016: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://www.readbyqxmd.com/read/27881568/incident-type-2-myocardial-infarction-in-a-cohort-of-patients-undergoing-coronary-or-peripheral-arterial-angiography
#13
Hanna K Gaggin, Yuyin Liu, Asya Lyass, Roland R van Kimmenade, Shweta R Motiwala, Noreen Kelly, Aditi Mallick, Parul U Gandhi, Nasrien E Ibrahim, Mandy Simon, Anju Bhardwaj, Arianna Belcher, Jamie E Harisiades, Joseph M Massaro, Ralph B D'Agostino, James L Januzzi
BACKGROUND: -Despite growing recognition of Type 2 myocardial infarction (T2MI; related to supply-demand mismatch), little is known about its risk factors or its association with outcome. METHODS: -A single center cohort of patients undergoing coronary or peripheral angiography with or without intervention was prospectively enrolled and followed for incident type 1 and T2MI, as well as major adverse cardiovascular events (MACE, a composite of all-cause death, non-fatal MI, heart failure, stroke, transient ischemic attack, peripheral arterial complication and cardiac arrhythmia)...
November 21, 2016: Circulation
https://www.readbyqxmd.com/read/27878869/effects-of-percutaneous-endoscopic-gastrostomy-on-survival-of-patients-in-a-persistent-vegetative-state-after-stroke
#14
Kunpeng Wu, Ying Chen, Caihong Yan, Zhijia Huang, Deming Wang, Peigen Gui, Juan Bao
AIMS AND OBJECTIVES: The aim of this study is to assess the effect of percutaneous endoscopic gastrostomy (PEG) on short- and long-term survival of patients in a persistent vegetative state (PVS) after stroke, and determine the relevant prognostic factors. BACKGROUND: Stroke may lead to a PVS, and the effect of PEG on survival of stroke patients in a PVS remains unclear. DESIGN: Prospective study. METHODS: A total of 97 stroke patients in a PVS hospitalized from January 2009 to December 2011 at the Second Hospital, University of South China, were assessed in this study...
November 22, 2016: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/27875347/severe-low-gradient-aortic-stenosis-with-preserved-ventricular-function-should-it-be-treated
#15
Giuseppe Di Pasquale, Gloria Vassilikì Coutsoumbas, Silvia Zagnoni
Exists a group of patients with small AVA (<0,6 cm/m), and normal LVEF (≥50%) who display a low transvalvular flow (LF) [index stroke volume (SVi)<35 ml/m2] and/or low transvalvular gradient (LG). This condition is called severe paradoxical aortic stenosis (SAO) LFLG. In many studies this condition was associated to increased mortality both with medical therapy and with surgical intervention. Crucial is define correctly the diagnostical criteria of this condition. Indeed there are several specific anatomical and functional characteristics useful in differentiating paradoxical severe aortic stenosis from the other forms of aortic stenosis...
November 19, 2016: Journal of Cardiovascular Medicine
https://www.readbyqxmd.com/read/27873227/the-relationship-between-aortic-root-size-and-hypertension-an-unsolved-conundrum
#16
Giuseppe Mulè, Emilio Nardi, Massimiliano Morreale, Antonella Castiglia, Giulio Geraci, Dario Altieri, Valentina Cacciatore, Margherita Schillaci, Francesco Vaccaro, Santina Cottone
Thoracic aortic aneurysms rupture and dissection are among the most devastating vascular diseases, being characterized by elevated mortality, despite improvements in diagnostic imaging and surgical techniques.An increased aortic root diameter (ARD) represents the main risk factor for thoracic aortic dissection and rupture and for aortic valve regurgitation.Even though arterial hypertension is commonly regarded as a predisposing condition for the development of thoracic aorta aneurysms, the role of blood pressure (BP) as determinant of aortic root enlargement is still controversial...
November 22, 2016: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/27869334/prediction-of-long-term-prognosis-by-heteroplasmy-levels-of-the-m-3243a-g-mutation-in-patients-with-the-mitochondrial-encephalomyopathy-lactic-acidosis-and-stroke-like-episodes-syndrome
#17
A Fayssoil, P Laforêt, W Bougouin, C Jardel, A Lombès, H M Bécane, N Berber, T Stojkovic, A Béhin, B Eymard, D Duboc, K Wahbi
BACKGROUND AND PURPOSE: Our aim was to determine the prognostic value of urine and blood heteroplasmy in patients with the m.3243A>G mutation. METHODS: Adults with the m.3243A>G mutation referred to our institution between January 2000 and May 2014 were retrospectively included. The relationship between their baseline clinical characteristics, their mutation load in urine and blood, and major adverse events (MAEs) during follow-up, defined as medical complications requiring a hospitalization or complicated by death, was studied...
November 21, 2016: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/27867302/current-and-emerging-uses-of-statins-in-clinical-therapeutics-a-review
#18
REVIEW
Jonathan T Davies, Spencer F Delfino, Chad E Feinberg, Meghan F Johnson, Veronica L Nappi, Joshua T Olinger, Anthony P Schwab, Hollie I Swanson
Statins, a class of cholesterol-lowering medications that inhibit 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase, are commonly administered to treat atherosclerotic cardiovascular disease. Statin use may expand considerably given its potential for treating an array of cholesterol-independent diseases. However, the lack of conclusive evidence supporting these emerging therapeutic uses of statins brings to the fore a number of unanswered questions including uncertainties regarding patient-to-patient variability in response to statins, the most appropriate statin to be used for the desired effect, and the efficacy of statins in treating cholesterol-independent diseases...
2016: Lipid Insights
https://www.readbyqxmd.com/read/27865637/increased-risk-of-mortality-after-lower-extremity-bypass-in-individuals-with-acute-kidney-injury-in-the-vascular-quality-initiative
#19
Erica Flores, Juan Pablo Lewinger, Vincent L Rowe, Karen Woo, Fred A Weaver, David Shavelle, Leonardo Clavijo, Parveen K Garg
OBJECTIVE: The development of acute kidney injury (AKI) and its effect on prognosis after lower extremity bypass (LEB) surgery have not been well described. We determined risk factors associated with AKI in patients undergoing infrainguinal LEB surgery and whether individuals with AKI are at increased risk for cardiovascular events and mortality. METHODS: Data for 12,907 operations entered in the Vascular Quality Initiative (VQI) registry from January 2012 through April 2015 were retrospectively reviewed...
November 16, 2016: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/27864581/prognostic-value-of-diffusion-weighted-imaging-dwi-apparent-diffusion-coefficient-adc-in-patients-with-hyperacute-cerebral-infarction-receiving-rt-pa-intravenous-thrombolytic-therapy
#20
Hai-Jing Sui, Cheng-Gong Yan, Zhen-Guo Zhao, Qing-Ke Bai
BACKGROUND The aim of this study was to investigate the potential value of apparent diffusion coefficient (ADC) of diffusion-weighted imaging (DWI) in the prognosis of patients with hyperacute cerebral infarction (HCI) receiving intravenous thrombolytic therapy with recombinant tissue plasminogen activator (rt-PA). MATERIAL AND METHODS From June 2012 to June 2015, 58 cases of HCI (<6 h) undergoing rt-PA intravenous thrombolytic therapy (thrombolysis group) and 70 cases of HCI (<6 h) undergoing conventional antiplatelet and anticoagulant therapy (control group) in the same period were collected...
November 19, 2016: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
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