keyword
https://read.qxmd.com/read/38650473/exploring-conventional-and-emerging-dehydration-technologies-for-slurry-liquid-food-matrices-and-their-impact-on-porosity-of-powders-a-comprehensive-review
#1
JOURNAL ARTICLE
Afroza Sultana, Sara Aghajanzadeh, Bruno Thibault, Cristina Ratti, Seddik Khalloufi
The contribution of dehydration to the growing market of food powders from slurry/liquid matrices is inevitable. To overcome the challenges posed by conventional drying technologies, several innovative approaches have emerged. However, industrial implementation is limited due to insufficient information on the best-suited drying technologies for targeted products. Therefore, this review aimed to compare various conventional and emerging dehydration technologies (such as active freeze, supercritical, agitated thin-film, and vortex chamber drying) based on their fundamental principles, potential applications, and limitations...
May 2024: Comprehensive Reviews in Food Science and Food Safety
https://read.qxmd.com/read/38650048/falling-and-rising-in-the-vortex-of-cancer-children-s-adaptation-with-cancer-a-qualitative-study
#2
JOURNAL ARTICLE
Fatemeh Sepahvand, Fatemeh Valizadeh, Kimia Karami, Babak Abdolkarimi, Fatemeh Ghasemi
BACKGROUND: Cancer is a considerable health problem worldwide and the second leading cause of death in children. It has many physical, psychological, and social consequences for children and their families. The ability to adapt to cancer plays a vital role in the recovery and quality of life of affected children. This study aimed to explain the adaptation of children with cancer to their disease. METHODS: This qualitative study adopted the directed content analysis approach based on the Roy nursing model...
April 22, 2024: BMC Psychology
https://read.qxmd.com/read/38648958/cli-a-new-protocol-for-the-isolation-of-lactic-acid-bacteria-from-complex-plant-samples
#3
JOURNAL ARTICLE
Mariannys Chavez, Sharon Viscardi, María José Ruiz, Eulàlia Sans-Serramitjana, Paola Durán
Lactic Acid Bacteria (LAB) are predominantly probiotic microorganisms and the most are Generally Recognized As Safe (GRAS). LAB inhabit in the human gut ecosystem and are largely found in fermented foods and silage. In the last decades, LAB have also has been found in plant microbiota as a new class of microbes with probiotic activity to plants. For this reason, today the scientific interest in the study and isolation of LAB for agronomic application has increased. However, isolation protocols from complex samples such as plant tissues are scarce and inefficient...
April 20, 2024: Journal of Microbiological Methods
https://read.qxmd.com/read/38647954/enhancing-mesenchymal-stem-cells-cultivated-on-microcarriers-in-spinner-flasks-via-impeller-design-optimization-for-aggregated-suspensions
#4
JOURNAL ARTICLE
Botao Zhang, Qiaohui Lu, Gance Dai, Yi Zhou, Qian Ye, Yan Zhou, Wen-Song Tan
During the ex vivo expansion of umbilical cord-derived mesenchymal stem cells (hUCMSCs) in a stirred tank bioreactor, the formation of cell-microcarrier aggregates significantly affects cell proliferation and physiological activity, making it difficult to meet the quantity and quality requirements for in vitro research and clinical applications. In this study, computational fluid dynamic (CFD) simulations were used to investigate the effect of an impeller structure in a commercial spinner flask on flow field structure, aggregate formation, and cellular physiological activity...
December 3, 2023: Bioresources and Bioprocessing
https://read.qxmd.com/read/38647365/ultralow-strain-induced-emergent-polarization-structures-in-a-flexible-freestanding-batio-3-membrane
#5
JOURNAL ARTICLE
Jie Wang, Zhen Liu, Qixiang Wang, Fang Nie, Yanan Chen, Gang Tian, Hong Fang, Bin He, Jinrui Guo, Limei Zheng, Changjian Li, Weiming Lü, Shishen Yan
The engineering of ferroic orders, which involves the evolution of atomic structure and local ferroic configuration in the development of next-generation electronic devices. Until now, diverse polarization structures and topological domains are obtained in ferroelectric thin films or heterostructures, and the polarization switching and subsequent domain nucleation are found to be more conducive to building energy-efficient and multifunctional polarization structures. In this work, a continuous and periodic strain in a flexible freestanding BaTiO3 membrane to achieve a zigzag morphology is introduced...
April 22, 2024: Advanced Science (Weinheim, Baden-Wurttemberg, Germany)
https://read.qxmd.com/read/38647257/paraxial-and-ray-approximations-of-acoustic-vortex-beams
#6
JOURNAL ARTICLE
Chirag A Gokani, Michael R Haberman, Mark F Hamilton
A compact analytical solution obtained in the paraxial approximation is used to investigate focused and unfocused vortex beams radiated by a source with a Gaussian amplitude distribution. Comparisons with solutions of the Helmholtz equation are conducted to determine bounds on the parameter space in which the paraxial approximation is accurate. A linear relation is obtained for the dependence of the vortex ring radius on the topological charge, characterized by its orbital number, in the far field of an unfocused beam and in the focal plane of a focused beam...
April 1, 2024: Journal of the Acoustical Society of America
https://read.qxmd.com/read/38646761/construction-of-yield-loss-indicators-for-cold-vortex-light-temperature-water-combined-stress-during-the-flowering-period-of-rice-in-northeast-china
#7
JOURNAL ARTICLE
Jia-Jia Lyu, Zheng Chu, Bai-Chao Li, Li-Juan Gong, Bao-Cai Zhou, Dan Liu, Dong-Ni Wang, Li-Xia Jiang
The construction of a yield loss evaluation index for the cold vortex type light-temperature-water composite adversity during rice flowering period in Northeast China is important for elucidating the impacts of cold vortex type composite disasters on rice yield loss in middle and high latitude areas. Moreover, it can provide meteorological support to ensure safe production of high-quality japonica rice in China and contribute to regional disaster reduction and efficiency improvement. By combining growth period data, meteorological data, and yield data, we delineated and constructed the composite stress occurrence index of cold vortex type light-temperature-water at the flowering stage of japonica...
March 18, 2024: Ying Yong Sheng Tai Xue Bao, the Journal of Applied Ecology
https://read.qxmd.com/read/38645321/laser-beam-self-focusing-in-silicon-at-an-absorbed-wavelength-by-a-vortex-beam-in-the-same-wavelength
#8
JOURNAL ARTICLE
Nadav Shabairou, Zeev Zalevsky, Moshe Sinvani
In this research, we present a novel approach to achieving super-resolution in silicon using the plasma dispersion effect (PDE) that temporarily controls the complex refractive index of matter. By employing a laser vortex pump beam, which is absorbed in the silicon, we can shape the complex refractive index as a gradient index (GRIN) lens, enabling the focusing of a laser probe beam within the material. Our study introduces a single beam at a wavelength of 775 nm for both the pump and the probe beams, offering tunable focusing capabilities and the potential to attain higher spatial resolution...
April 16, 2024: ACS Omega
https://read.qxmd.com/read/38639114/elucidating-structural-configuration-of-lipid-assemblies-for-mrna-delivery-systems
#9
JOURNAL ARTICLE
Hyunhyuk Tae, Soohyun Park, Li Yang Tan, Chungmo Yang, Yong-An Lee, Younghwan Choe, Torsten Wüstefeld, Sangyong Jung, Nam-Joon Cho
The development of mRNA delivery systems utilizing lipid-based assemblies holds immense potential for precise control of gene expression and targeted therapeutic interventions. Despite advancements in lipid-based gene delivery systems, a critical knowledge gap remains in understanding how the biophysical characteristics of lipid assemblies and mRNA complexes influence these systems. Herein, we investigate the biophysical properties of cationic liposomes and their role in shaping mRNA lipoplexes by comparing various fabrication methods...
April 19, 2024: ACS Nano
https://read.qxmd.com/read/38637571/exciton-polariton-condensation-from-bound-states-in-the-continuum-at-room-temperature
#10
JOURNAL ARTICLE
Xianxin Wu, Shuai Zhang, Jiepeng Song, Xinyi Deng, Wenna Du, Xin Zeng, Yuyang Zhang, Zhiyong Zhang, Yuzhong Chen, Yubin Wang, Chuanxiu Jiang, Yangguang Zhong, Bo Wu, Zhuoya Zhu, Yin Liang, Qing Zhang, Qihua Xiong, Xinfeng Liu
Exciton-polaritons (polaritons) resulting from the strong exciton-photon interaction stimulates the development of novel low-threshold coherent light sources to circumvent the ever-increasing energy demands of optical communications1-3 . Polaritons from bound states in the continuum (BICs) are promising for Bose-Einstein condensation owing to their theoretically infinite quality factors, which provide prolonged lifetimes and benefit the polariton accumulations4-7 . However, BIC polariton condensation remains limited to cryogenic temperatures ascribed to the small exciton binding energies of conventional material platforms...
April 18, 2024: Nature Communications
https://read.qxmd.com/read/38637308/enhanced-photo-excitation-and-angular-momentum-imprint-of-gray-excitons-in-wse-2-monolayers-by-spin-orbit-coupled-vector-vortex-beams
#11
JOURNAL ARTICLE
Oscar Javier Gomez Sanchez, Guan-Hao Peng, Wei-Hua Li, Ching-Hung Shih, Chao-Hsin Chien, Shun-Jen Cheng
A light beam can be spatially structured in the complex amplitude to possess orbital angular momentum (OAM), which introduces an extra degree of freedom alongside the intrinsic spin angular momentum (SAM) associated with circular polarization. Furthermore, superimposing two such twisted light (TL) beams with distinct SAM and OAM produces a vector vortex beam (VVB) in nonseparable states where not only complex amplitude but also polarization is spatially structured and entangled with each other. In addition to the nonseparability, the SAM and OAM in a VVB are intrinsically coupled by the optical spin-orbit interaction and constitute the profound spin-orbit physics in photonics...
April 18, 2024: ACS Nano
https://read.qxmd.com/read/38636134/development-of-dispersive-solid-phase-extraction-based-on-magnetic-metal-organic-framework-for-the-extraction-of-sunitinib-in-biological-samples-and-its-determination-by-high-performance-liquid-chromatography-tandem-mass-spectrometry
#12
JOURNAL ARTICLE
Mandana Hassani Nouriyeh, Mohammad Reza Afshar Mogaddam, Mahboob Nemati, Mir Ali Farajzadeh, Aysa Abbasalizadeh, Ali Shahedi Hojghan
Herein, a simple, sensitive, and reliable dispersive solid phase extraction was reported for the efficient extraction of sunitinib from biological samples. To facilitate the extraction of the desired analyte from urine and plasma samples, magnetic MIL-101Cr (NH2 ) @SiO2 @ NiFe2 O4 was synthesized by a hydrothermal method and applied as an effective sorbent during the extraction process. After adsorption of the drug using 10 mg of MIL-101Cr (NH2 ) @ SiO2 @ NiFe2 O4 nanoparticles through vortexing (1 min), the sorbent was separatedfrom the sample solution using a magnet...
March 29, 2024: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://read.qxmd.com/read/38634601/shear-induced-nonequilibrium-patterns-in-lipid-bilayer-membranes-exhibiting-phase-separation
#13
JOURNAL ARTICLE
Tsutomu Hamada, Shino Mizuno, Hiroyuki Kitahata
The nonequilibrium dynamics of a fluid lipid membrane under external stimuli is an important issue that spans disciplines such as soft matter, biophysical chemistry, and interface science. This study investigated the dynamic response of lipid vesicles with order-disorder phase separation, which mimics a plasma membrane heterogeneity, to shear flow. Lipid vesicles were immobilized in a microfluidic chamber, and shear-induced nonequilibrium patterns on the membrane surface were observed by an optical microscope...
April 18, 2024: Langmuir: the ACS Journal of Surfaces and Colloids
https://read.qxmd.com/read/38634061/pretreatment-and-analysis-techniques-development-of-tkis-in-biological-samples-for-pharmacokinetic-studies-and-therapeutic-drug-monitoring
#14
REVIEW
Lan Chen, Yuan Zhang, Yi-Xin Zhang, Wei-Lai Wang, De-Mei Sun, Peng-Yun Li, Xue-Song Feng, Yue Tan
Tyrosine kinase inhibitors (TKIs) have emerged as the first-line small molecule drugs in many cancer therapies, exerting their effects by impeding aberrant cell growth and proliferation through the modulation of tyrosine kinase-mediated signaling pathways. However, there exists a substantial inter-individual variability in the concentrations of certain TKIs and their metabolites, which may render patients with compromised immune function susceptible to diverse infections despite receiving theoretically efficacious anticancer treatments, alongside other potential side effects or adverse reactions...
April 2024: Journal of Pharmaceutical Analysis
https://read.qxmd.com/read/38633472/adding-vortexing-to-the-maki-technique-provides-no-benefit-for-the-diagnosis-of-catheter-colonization-or-catheter-related-bacteremia
#15
JOURNAL ARTICLE
Leonardo Lorente, Maria Lecuona Fernandez, Adriana González-Mesa, Judith Oliveras-Roura, Cristina Rosado, Pablo Cabrera, Emma Casal, Alejandro Jiménez, María Luisa Mora, Ana Madueño
BACKGROUND: A previous study compared vortexing and Maki techniques for the diagnosis of catheter-related bloodstream infection (CRBSI), and concluded that vortexing was not superior to Maki method. AIM: To determine whether the combined use of vortexing and Maki techniques provides profitability versus the Maki technique for the diagnosis of catheter tip colonization (CTC) and CRBSI. METHODS: Observational and prospective study carried out in an Intensive Care Unit...
March 9, 2024: World Journal of Critical Care Medicine
https://read.qxmd.com/read/38632791/quantum-states-resembling-classical-periodic-trajectories-in-mesoscopic-elliptic-billiards
#16
JOURNAL ARTICLE
Jesús G Riestra, Julio C Gutiérrez-Vega
A quantum wave function with localization on classical periodic orbits in a mesoscopic elliptic billiard has been achieved by appropriately superposing nearly degenerate eigenstates expressed as products of Mathieu functions. We analyze and discuss the rotational and librational regimes of motion in the elliptic billiard. Simplified line equations corresponding to the classical trajectories can be extracted from the quantum state as an integral equation involving angular Mathieu functions. The phase factors appearing in the integrals are connected to the classical initial positions and velocity components...
March 2024: Physical Review. E
https://read.qxmd.com/read/38630812/topology-guided-polar-ordering-of-collective-cell-migration
#17
JOURNAL ARTICLE
Emma Lång, Anna Lång, Pernille Blicher, Torbjørn Rognes, Paul Gunnar Dommersnes, Stig Ove Bøe
The ability of epithelial monolayers to self-organize into a dynamic polarized state, where cells migrate in a uniform direction, is essential for tissue regeneration, development, and tumor progression. However, the mechanisms governing long-range polar ordering of motility direction in biological tissues remain unclear. Here, we investigate the self-organizing behavior of quiescent epithelial monolayers that transit to a dynamic state with long-range polar order upon growth factor exposure. We demonstrate that the heightened self-propelled activity of monolayer cells leads to formation of vortex-antivortex pairs that undergo sequential annihilation, ultimately driving the spread of long-range polar order throughout the system...
April 19, 2024: Science Advances
https://read.qxmd.com/read/38629261/imaging-of-voltage-controlled-switching-of-magnetization-in-highly-magnetostrictive-epitaxial-fe-ga-microstructures
#18
JOURNAL ARTICLE
Maite Goiriena, Zhuyun Xiao, Rachel Steinhardt, Victor Estrada, Nobumichi Tamura, Rajesh V Chopdekar, Alpha T N'Diaye, Abdon Sepúlveda, Darrell G Schlom, Rob N Candler, Jeffrey Bokor
The magnetoelectric behavior of epitaxial Fe-Ga microstructures on top of a (001)-oriented PMN-PT piezoelectric substrate is imaged with magnetic X-ray microscopy. Additionally, the micron-scale strain distribution in PMN-PT is characterized by X-ray microdiffraction and examined with respect to the results of the Fe-Ga magnetoelectric switching. The magnetic reorientation of Fe-Ga is found to be strongly correlated with size, shape, and crystallographic orientation of the microstructures. In the case of square-shaped structures, size dictates the influence of the strain distribution on both the initialization of the ground state and on the magnetic reorientation during application of voltage...
April 17, 2024: Nanoscale
https://read.qxmd.com/read/38627648/detecting-androgen-receptor-ar-ar-variant-7-ar-v7-prostate-specific-membrane-antigen-psma-and-prostate-specific-antigen-psa-gene-expression-in-ctcs-and-plasma-exosome-derived-cfrna-in-patients-with-metastatic-castration-resistant-prostate-cancer-mcrpc-by-integrating
#19
JOURNAL ARTICLE
Haiyan E Liu, Meghah Vuppalapaty, Christian R Hoerner, Colin P Bergstrom, Michael Chiu, Clementine Lemaire, James Che, Amanpreet Kaur, Adam Dimmick, Sean Liu, Thomas J Metzner, Menna Araya, Steve Crouse, Markus Sprenger-Haussels, Martin Schlumpberger, John T Leppert, Siegfried Hauch, Elodie Sollier, Alice C Fan
BACKGROUND: Therapies for metastatic castration-resistant prostate cancer (mCRPC) include targeting the androgen receptor (AR) with androgen receptor inhibitors (ARIs) and prostate-specific membrane antigen (PSMA). Having the ability to detect AR, AR splice variant 7 (AR-V7), or PSMA in circulating tumor cells (CTCs) or circulating exosomal cell-free RNA (cfRNA) could be helpful to guide selection of the appropriate therapy for each individual patient. The Vortex Biosciences VTX-1 system is a label-free CTC isolation system that enables the detection of the expression of multiple genes in both CTCs and exosomal cfRNA from the same blood sample in patients with mCRPC...
April 16, 2024: BMC Cancer
https://read.qxmd.com/read/38627252/selective-sparse-sampling-of-water-droplets-in-oil-with-acoustic-tweezers
#20
JOURNAL ARTICLE
Siying Lin, Antoine Riaud, Jia Zhou
In microfluidics, water droplets are often used as independent biochemical microreactor units, enabling the implementation of massively parallel screening assays where only a few of the reacting water droplets yield a positive result. However, sampling the product of these few successful reactions is an unsolved challenge. One possible solution is to use acoustic tweezers, which are lab-free, easily miniaturized, and biocompatible manipulation tools, and existing acoustic tweezers manipulating particles or cells, and water droplet manipulation in oil with an acoustic tweezer is absent...
April 16, 2024: ACS Sensors
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