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https://www.readbyqxmd.com/read/29666821/probiotics-for-the-control-of-helminth-zoonosis
#1
REVIEW
Abadi Amare Reda
This paper is a comprehensive, concise, and an up to date review about probiotics effect and mechanisms against helminth infections of zoonotic importance. Zoonoses are diseases that can be transmitted from animals to humans in a reversible way. Despite zoonotic helminth diseases being still a challenge to the public health and the agriculture industries globally, they were still neglected in both human and veterinary medicine. Moreover, the increasing emergence of anthelmintic drug resistance constitutes failures of most disease control strategies, alarming for a quest to new alternative control approaches...
2018: Journal of Veterinary Medicine
https://www.readbyqxmd.com/read/29660159/cannabis-and-anti-cancer-drugs-societal-usage-and-expected-pharmacological-interactions-a-review
#2
REVIEW
Régis Bouquié, Guillaume Deslandes, Hélène Mazaré, Marion Cogné, Julien Mahé, Matthieu Grégoire, Pascale Jolliet
Cannabis is a plant that has been used for centuries to relieve a wide range of symptoms. Since the 1960s, interest in medical research into this plant has grown steadily. Already very popular for recreational use, a growing number of consumers not accustomed to using cannabis for psychoactive purposes, have begun to use it as an alternative or complement to mainstream pharmaceutical medicines. The principal unsubstantiated or "social" uses of cannabis are based mainly on data that is at best controversial, but usually not scientifically proven...
April 16, 2018: Fundamental & Clinical Pharmacology
https://www.readbyqxmd.com/read/29653250/pluripotent-stem-cell-based-therapy-for-parkinson-s-disease-current-status-and-future-prospects
#3
REVIEW
Kai-C Sonntag, Bin Song, Nayeon Lee, Jin Hyuk Jung, Young Cha, Pierre Leblanc, Carolyn Neff, Sek Won Kong, Bob S Carter, Jeffrey Schweitzer, Kwang-Soo Kim
Parkinson's disease (PD) is one of the most common neurodegenerative disorders, which affects about 0.3% of the general population. As the population in the developed world ages, this creates an escalating burden on society both in economic terms and in quality of life for these patients and for the families that support them. Although currently available pharmacological or surgical treatments may significantly improve the quality of life of many patients with PD, these are symptomatic treatments that do not slow or stop the progressive course of the disease...
April 10, 2018: Progress in Neurobiology
https://www.readbyqxmd.com/read/29653249/directing-neuronal-cell-fate-in-vitro-achievements-and-challenges
#4
REVIEW
R J M Riemens, D L van den Hove, M Esteller, R Delgado-Morales
Human pluripotent stem cell (PSC) technology and direct somatic cell reprogramming have opened up a promising new avenue in the field of neuroscience. These recent advances allow researchers to obtain virtually any cell type found in the human brain, making it possible to produce and study functional neurons in laboratory conditions for both scientific and medical purposes. Although distinct approaches have shown to be successful in directing neuronal cell fate in vitro, their refinement and optimization, as well as the search for alternative approaches, remains necessary to help realize the full potential of the eventually derived neuronal populations...
April 10, 2018: Progress in Neurobiology
https://www.readbyqxmd.com/read/29650893/-towards-development-of-innovative-cancer-therapies-trans-omics-approach
#5
Reika Kawabata-Iwakawa, Masahiko Nishiyama
Comprehensive genomic and transcriptome analyses using next-generation sequencing(NGS)analysis has lead a discovery of a variety of novel driver gene mutations and new therapeutic targets for cancer patients, and has remarkably improved outcome of the patients through the development novel molecular targeting drugs. Even so, in so-called intractable or refractory cancers, those "druggable"alterations common to the diseases are rarely found due to the high diversity of the tumor. Furthermore, most of molecular target therapy is known to acquire the resistance to the drug by means of multiple factors such as up-regulation of the partially inhibited pathway, mutation of the target, activation of alternative pathways, histological translocation, and oncogene de-addiction...
March 2018: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29623836/microbial-biofilm-and-quorum-sensing-inhibition-endowment-of-medicinal-plants-to-combat-multidrug-resistant-bacteria
#6
Dinesh Kumar Mehta, Rina Das
Continued emergence and spread of multidrug- resistant bacteria behooved the development of alternative treatment strategies, including antimicrobial drugs. A hopeful approach is to target cell-to-cell communications, commonly known as quorum-sensing (QS) and microbial biofilm formation. Quorum Sensing is machinery used by bacteria to determine their physiological behavior and coordinate gene expression based on the cell to cell signaling. Many physiological functions of bacteria are controlled by quorum sensings such as virulence, motility, sporulation, luminescence, and biofilm formation...
April 5, 2018: Current Drug Targets
https://www.readbyqxmd.com/read/29623808/alternative-medicine-in-north-america-a-christian-pastoral-response
#7
E Janet Warren
Complementary and Alternative Medicine is popular among North Americans. However, there are many areas of concern, both scientific and spiritual, about its appropriate use. Those involved in pastoral care may be consulted for advice and therefore should be knowledgeable about Complementary and Alternative Medicine. This paper reviews and evaluates it from a Christian perspective, and offers suggestions for a pastoral response.
March 2018: Journal of Pastoral Care & Counseling: JPCC
https://www.readbyqxmd.com/read/29622824/traditional-medicines-and-alternative-practice-in-the-management-of-prostate-diseases-in-southern-ghana
#8
Mathew Y Kyei, George O Klufio, Ali Ayamba, Sherif Mohammed
Objective: This study was aimed at identifying Ghanaian traditional medicines used for the management of prostate diseases and their constituents. Reviews of studies conducted on them are also presented. Methodology: This was a prospective study. Traditional Medicine samples from consecutive patients with either lower urinary symptoms (LUTS) presenting at the Urology Unit of the Korle Bu Teaching Hospital (KBTH) in Accra from January 2015 to June 2016 and had a prior treatment with traditional medicines, had the samples retrieved...
September 2017: Ghana Medical Journal
https://www.readbyqxmd.com/read/29619627/new-advances-in-acute-postoperative-pain-management
#9
REVIEW
Sukanya Mitra, Daniel Carlyle, Gopal Kodumudi, Vijay Kodumudi, Nalini Vadivelu
PURPOSE OF REVIEW: Postoperative pain remains one of the most common challenges following inpatient and outpatient surgeries. With our advances in modern medicine, pain following surgical procedures still remains a challenge, though significant accomplishments have been made over the past few decades. This article highlights some of the promising new advances and approaches in postoperative pain management. RECENT FINDINGS: Over the last decade, Enhanced Recovery after Surgery (ERAS) pathways and protocols are becoming the benchmark standards for enhancing postoperative recovery...
April 4, 2018: Current Pain and Headache Reports
https://www.readbyqxmd.com/read/29619575/the-evidence-for-the-role-of-nutraceuticals-in-the-management-of-pediatric-migraine-a-review
#10
REVIEW
Serena L Orr
PURPOSE OF REVIEW: Nutraceuticals are a form of complementary and alternative medicine that is commonly used by children and adolescents with migraine. In this review, observational studies, randomized controlled trials, systematic reviews, and meta-analyses on the efficacy and safety of single compound nutraceuticals for the management of migraine in children and adolescents were identified through a literature search of MEDLINE, Embase, and EBM Reviews-Cochrane Central Register of Controlled Trials...
April 4, 2018: Current Pain and Headache Reports
https://www.readbyqxmd.com/read/29619352/complementary-and-alternative-medicines-and-patients-with-breast-cancer-a-case-of-mortality-and-systematic-review-of-patterns-of-use-in-patients-with-breast-cancer
#11
REVIEW
Grayson A Roumeliotis, Genevieve Dostaler, Kirsty U Boyd
Background: The use of complementary and alternative medicines (CAMs) is common among women being treated for breast cancer. A recent mortality associated with CAM at our center precipitated a systematic review of the Cochrane, EMBASE, and PubMed databases to identify English manuscripts including "CAM" and "breast cancer." Methods: Papers included for review were selected based on predefined inclusion and exclusion criteria. The primary outcome was the use of CAM by women with breast cancer...
November 2017: Plastic Surgery
https://www.readbyqxmd.com/read/29611474/glycosides-from-medicinal-plants-as-potential-anticancer-agents-emerging-trends-towards-future-drugs
#12
Haroon Khan, Mina Saeedi, Seyed Mohammad Nabavi, Mohammad S Mubarak, Anupam Bishayee
BACKGROUND: Cancer continues to be a global burden, despite the advancement of various technological and pharmaceutical improvements over the past two decades. Methods for treating cancer include surgery, radiotherapy and chemotherapy in addition to other specialized techniques. On the other hand, medicinal plants have been traditionally employed either as the complementary medicine or dietary agents in the treatment and management of cancer. Medicinal plants are a rich source of secondary metabolites with interesting biological and pharmacological activities...
April 3, 2018: Current Medicinal Chemistry
https://www.readbyqxmd.com/read/29609928/complementary-and-alternative-medicine-utilisation-for-the-management-of-acute-respiratory-tract-infection-in-children-a-systematic-review
#13
REVIEW
S Lucas, M Leach, S Kumar
INTRODUCTION: As many as one in two children across the globe use complementary and alternative medicine (CAM) to manage a health condition. Despite the high prevalence of use, there is still limited information on the types of CAM used in children, particularly for the management of one of the most common childhood health complaints - acute respiratory tract infection (ARTI). This systematic review was undertaken to address this knowledge gap. METHODS: Eligible studies reporting the use of CAM in children with ARTI were identified using a targeted search of seven electronic databases and the grey literature...
April 2018: Complementary Therapies in Medicine
https://www.readbyqxmd.com/read/29609927/complementary-and-alternative-medicine-for-rheumatic-diseases-a-systematic-review-of-randomized-controlled-trials
#14
REVIEW
Jie Kie Phang, Yu Heng Kwan, Hendra Goh, Victoria Ie Ching Tan, Julian Thumboo, Truls Østbye, Warren Fong
OBJECTIVES: To summarize all good quality randomized controlled trials (RCTs) using complementary and alternative medicine (CAM) interventions in patients with rheumatic diseases. METHODS: A systematic literature review guided by the Preferred Reporting Items for Systematic review and Meta-Analysis (PRISMA) was performed. We excluded non-English language articles and abstract-only publications. Due to the large number of RCTs identified, we only include "good quality" RCTs with Jadad score of five...
April 2018: Complementary Therapies in Medicine
https://www.readbyqxmd.com/read/29609592/a-systematic-review-of-health-status-health-seeking-behaviour-and-healthcare-utilisation-of-low-socioeconomic-status-populations-in-urban-singapore
#15
REVIEW
Catherine Qiu Hua Chan, Kheng Hock Lee, Lian Leng Low
INTRODUCTION: It is well-established that low socioeconomic status (SES) influences one's health status, morbidity and mortality. Housing type has been used as an indicator of SES and social determinant of health in some studies. In Singapore, home ownership is among the highest in the world. Citizens who have no other housing options are offered heavily subsidised rental housings. Residents staying in such rental housings are characterised by low socioeconomic status. Our aim is to review studies on the association between staying in public rental housing in Singapore and health status...
April 2, 2018: International Journal for Equity in Health
https://www.readbyqxmd.com/read/29601622/a-systematic-review-of-topical-finasteride-in-the-treatment-of-androgenetic-alopecia-in-men-and-women
#16
Sung Won Lee, Margit Juhasz, Pezhman Mobasher, Chloe Ekelem, Natasha Atanaskova Mesinkovska
INTRODUCTION: Currently, only topical minoxidil (MNX) and oral finasteride (FNS) are approved by the Food and Drug Administration (FDA) and the European Medicines Agency (EMA) for the treatment of androgenetic alopecia. Although FNS is efficacious for hair regrowth, its systemic use is associated with side effects limiting long-term utilization. Exploring topical FNS as an alternative treatment regimen may prove promising. METHODS: A search was conducted to identify studies regarding human in vivo topical FNS treatment efficacy including clinically relevant case reports, randomized controlled trials (RCTs), and prospective studies...
April 1, 2018: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/29596299/a-narrative-review-on-contrast-enhanced-ultrasound-in-aortic-endograft-endoleak-surveillance
#17
Sriharsha Gummadi, John R Eisenbrey, Andrej Lyshchik
Endovascular repair of abdominal aortic aneurysms have been performed successfully since 1991. However, 20% to 50% of these patients may develop an endoleak or continued aneurysmal sac expansion or perfusion despite stent graft coverage. Current recommendations suggest lifelong surveillance with computed tomographic angiography (CTA) at least 1 month after intervention and yearly after that. In select patients with a stable aneurysm sac on computed tomography performed 1 year after treatment, future screening could be performed with ultrasonography...
March 29, 2018: Ultrasound Quarterly
https://www.readbyqxmd.com/read/29595103/application-of-medicinal-plants-as-a-source-for-therapeutic-agents-against-streptococcus-pyogenes-infections
#18
Adil Mohd, H P Vasantha Rupasinghe
Streptococcus pyogenes, a major human pathogen, causes a wide variety of invasive systemic infections such as acute pharyngitis, skin and soft-tissue infections, especially necrotizing fasciitis. This Gram-positive bacterium has an ability to form mature biofilm and this sessile lifestyle plays an important role in S. pyogenes pathogenicity. The virulence of these bacteria is further strengthened by its ability to communicate within the micro-colonies through quorum sensing. Most treatments are now aimed at either elimination of this bacterium or suppression of its virulence...
March 29, 2018: Current Drug Metabolism
https://www.readbyqxmd.com/read/29594358/production-of-l-valine-from-metabolically-engineered-corynebacterium-glutamicum
#19
REVIEW
Xiaoyuan Wang, Hailing Zhang, Peter J Quinn
L-Valine is one of the three branched-chain amino acids (valine, leucine, and isoleucine) essential for animal health and important in metabolism; therefore, it is widely added in the products of food, medicine, and feed. L-Valine is predominantly produced through microbial fermentation, and the production efficiency largely depends on the quality of microorganisms. In recent years, continuing efforts have been made in revealing the mechanisms and regulation of L-valine biosynthesis in Corynebacterium glutamicum, the most utilitarian bacterium for amino acid production...
March 29, 2018: Applied Microbiology and Biotechnology
https://www.readbyqxmd.com/read/29590247/what-do-cochrane-systematic-reviews-say-about-non-surgical-interventions-for-urinary-incontinence-in-women
#20
Anderson Adriano Leal Freitas da Costa, Igor Martins Vasconcellos, Rafael Leite Pacheco, Zsuzsanna Ilona Katalin de Jármy Di Bella, Rachel Riera
BACKGROUND: Urinary incontinence is a highly prevalent condition that impacts self-esteem and overall quality of life. Many non-surgical treatment options are available, ranging from pharmacological approaches to pelvic exercises. We aimed to summarize the available evidence regarding these non-surgical interventions. DESIGN AND SETTING: Review of systematic reviews, conducted in the Discipline of Evidence-Based Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo (EPM-UNIFESP)...
January 2018: São Paulo Medical Journal, Revista Paulista de Medicina
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