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3D Tomosynthesis

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https://www.readbyqxmd.com/read/29176921/foveated-model-observers-to-predict-human-performance-in-3d-images
#1
Miguel A Lago, Craig K Abbey, Miguel P Eckstein
We evaluate 3D search requires model observers that take into account the peripheral human visual processing (foveated models) to predict human observer performance. We show that two different 3D tasks, free search and location-known detection, influence the relative human visual detectability of two signals of different sizes in synthetic backgrounds mimicking the noise found in 3D digital breast tomosynthesis. One of the signals resembled a microcalcification (a small and bright sphere), while the other one was designed to look like a mass (a larger Gaussian blob)...
February 11, 2017: Proceedings of SPIE
https://www.readbyqxmd.com/read/29066138/evidence-on-synthesized-two-dimensional-mammography-versus-digital-mammography-when-using-tomosynthesis-three-dimensional-mammography-for-population-breast-cancer-screening
#2
REVIEW
Nehmat Houssami
One limitation of using digital breast tomosynthesis (3-dimensional [3D] mammography) technology with conventional (2-dimensional [2D]) mammography for breast cancer (BC) screening is the increased radiation dose from dual acquisitions. To resolve this problem, synthesized 2D (s2D) reconstruction images similar to 2D mammography were developed using tomosynthesis acquisitions. The present review summarizes the evidence for s2D versus digital mammography (2D) when using tomosynthesis (3D) for BC screening to address whether using s2D instead of 2D (alongside 3D) will yield similar detection measures...
September 28, 2017: Clinical Breast Cancer
https://www.readbyqxmd.com/read/29047034/quantitative-volumetric-k-means-cluster-segmentation-of-fibroglandular-tissue-and-skin-in-breast-mri
#3
Anton Niukkanen, Otso Arponen, Aki Nykänen, Amro Masarwah, Anna Sutela, Timo Liimatainen, Ritva Vanninen, Mazen Sudah
Mammographic breast density (MBD) is the most commonly used method to assess the volume of fibroglandular tissue (FGT). However, MRI could provide a clinically feasible and more accurate alternative. There were three aims in this study: (1) to evaluate a clinically feasible method to quantify FGT with MRI, (2) to assess the inter-rater agreement of MRI-based volumetric measurements and (3) to compare them to measurements acquired using digital mammography and 3D tomosynthesis. This retrospective study examined 72 women (mean age 52...
October 18, 2017: Journal of Digital Imaging: the Official Journal of the Society for Computer Applications in Radiology
https://www.readbyqxmd.com/read/28943698/4d-dsa-reconstruction-using-tomosynthesis-projections
#4
Marc Buehler, Jordan M Slagowski, Charles A Mistretta, Charles M Strother, Michael A Speidel
We investigate the use of tomosynthesis in 4D DSA to improve the accuracy of reconstructed vessel time-attenuation curves (TACs). It is hypothesized that a narrow-angle tomosynthesis dataset for each time point can be exploited to reduce artifacts caused by vessel overlap in individual projections. 4D DSA reconstructs time-resolved 3D angiographic volumes from a typical 3D DSA scan consisting of mask and iodine-enhanced C-arm rotations. Tomosynthesis projections are obtained either from a conventional C-arm rotation, or from an inverse geometry scanning-beam digital x-ray (SBDX) system...
February 2017: Proceedings of SPIE
https://www.readbyqxmd.com/read/28943696/automated-3d-coronary-sinus-catheter-detection-using-a-scanning-beam-digital-x-ray-system
#5
David A P Dunkerley, Jordan M Slagowski, Lindsay E Bodart, Michael A Speidel
Scanning-beam digital x-ray (SBDX) is an inverse geometry x-ray fluoroscopy system capable of tomosynthesis-based 3D tracking of catheter electrodes concurrent with fluoroscopic display. To facilitate respiratory motion-compensated 3D catheter tracking, an automated coronary sinus (CS) catheter detection algorithm for SBDX was developed. The technique uses the 3D localization capability of SBDX and prior knowledge of the catheter shape. Candidate groups of points representing the CS catheter are obtained from a 3D shape-constrained search...
February 2017: Proceedings of SPIE
https://www.readbyqxmd.com/read/28901614/investigating-simulation-based-metrics-for-characterizing-linear-iterative-reconstruction-in-digital-breast-tomosynthesis
#6
Sean D Rose, Adrian A Sanchez, Emil Y Sidky, Xiaochuan Pan
PURPOSE: Simulation-based image quality metrics are adapted and investigated for characterizing the parameter dependences of linear iterative image reconstruction for DBT. METHODS: Three metrics based on a 2D DBT simulation are investigated: (1) a root-mean-square-error (RMSE) between the test phantom and reconstructed image, (2) a gradient RMSE where the comparison is made after taking a spatial gradient of both image and phantom, and (3) a region-of-interest (ROI) Hotelling observer (HO) for signal-known-exactly/background-known-exactly (SKE/BKE) and signal-known-exactly/background-known-statistically (SKE/BKS) detection tasks...
September 2017: Medical Physics
https://www.readbyqxmd.com/read/28713173/a-standard-mammography-unit-standard-3d-ultrasound-probe-fusion-prototype-first-results
#7
Rüdiger Schulz-Wendtland, Sebastian M Jud, Peter A Fasching, Arndt Hartmann, Marcus Radicke, Claudia Rauh, Michael Uder, Marius Wunderle, Paul Gass, Hanna Langemann, Matthias W Beckmann, Julius Emons
AIM: The combination of different imaging modalities through the use of fusion devices promises significant diagnostic improvement for breast pathology. The aim of this study was to evaluate image quality and clinical feasibility of a prototype fusion device (fusion prototype) constructed from a standard tomosynthesis mammography unit and a standard 3D ultrasound probe using a new method of breast compression. MATERIALS AND METHODS: Imaging was performed on 5 mastectomy specimens from patients with confirmed DCIS or invasive carcinoma (BI-RADS (™) 6)...
June 2017: Geburtshilfe und Frauenheilkunde
https://www.readbyqxmd.com/read/28665291/the-compressed-breast-during-mammography-and-breast-tomosynthesis-in-vivo-shape-characterization-and-modeling
#8
Alejandro Rodríguez-Ruiz, Greeshma A Agasthya, Ioannis Sechopoulos
To characterize and develop a patient-based 3D model of the compressed breast undergoing mammography and breast tomosynthesis. During this IRB-approved, HIPAA-compliant study, 50 women were recruited to undergo 3D breast surface imaging with structured light (SL) during breast compression, along with simultaneous acquisition of a tomosynthesis image. A pair of SL systems were used to acquire 3D surface images by projecting 24 different patterns onto the compressed breast and capturing their reflection off the breast surface in approximately 12-16 s...
August 7, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28483356/evaluation-of-a-breast-software-model-for-2d-and-3d-x-ray-imaging-studies-of-the-breast
#9
Yanka Baneva, Kristina Bliznakova, Lesley Cockmartin, Stoyko Marinov, Ivan Buliev, Giovanni Mettivier, Hilde Bosmans, Paolo Russo, Nicholas Marshall, Zhivko Bliznakov
INTRODUCTION: In X-ray imaging, test objects reproducing breast anatomy characteristics are realized to optimize issues such as image processing or reconstruction, lesion detection performance, image quality and radiation induced detriment. Recently, a physical phantom with a structured background has been introduced for both 2D mammography and breast tomosynthesis. A software version of this phantom and a few related versions are now available and a comparison between these 3D software phantoms and the physical phantom will be presented...
May 5, 2017: Physica Medica: PM
https://www.readbyqxmd.com/read/28436856/task-based-modeling-of-a-5k-ultra-high-resolution-medical-imaging-system-for-digital-breast-tomosynthesis
#10
Chumin Zhao, Jerzy Kanicki
High-resolution, low-noise X-ray detectors based on CMOS active pixel sensor (APS) technology have demonstrated superior imaging performance for digital breast tomosynthesis (DBT). This paper presents a task-based model for a high-resolution medical imaging system to evaluate its ability to detect simulated microcalcifications and masses as lesions for breast cancer. A 3-D cascaded system analysis for a 50- [Formula: see text] pixel pitch CMOS APS X-ray detector was integrated with an object task function, a medical imaging display model, and the human eye contrast sensitivity function to calculate the detectability index and area under the ROC curve (AUC)...
September 2017: IEEE Transactions on Medical Imaging
https://www.readbyqxmd.com/read/28391808/fully-automated-nipple-detection-in-digital-breast-tomosynthesis
#11
Seung-Hoon Chae, Ji-Wook Jeong, Jang-Hwan Choi, Eun Young Chae, Hak Hee Kim, Young-Wook Choi, Sooyeul Lee
BACKGROUND AND OBJECTIVE: We propose a nipple detection algorithm for use with digital breast tomosynthesis (DBT) images. DBT images have been developed to overcome the weaknesses of 2D mammograms for denser breasts by providing 3D breast images. The nipple location acts as an invaluable landmark in DBT images for aligning the right and left breasts and describing the relative location of any existing lesions. METHODS: Nipples may be visible or invisible in a breast image, and therefore a nipple detection method must be able to detect the nipples for both cases...
May 2017: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/28268510/simplified-computer-aided-detection-scheme-of-microcalcification-clusters-in-digital-breast-tomosynthesis-images
#12
Ji-Wook Jeong, Seung-Hoon Chae, Eun Young Chae, Hak Hee Kim, Young Wook Choi, Sooyeul Lee
A computer-aided detection (CADe) algorithm for clustered microcalcifications (MCs) in reconstructed digital breast tomosynthesis (DBT) images is suggested. The MC-like objects were enhanced by a Hessian-based 3D calcification response function, and a signal-to-noise ratio (SNR) enhanced image was also generated to screen the MC clustering seed objects. A connected component segmentation method was used to detect the cluster seed objects, which were considered as potential clustering centers of MCs. Bounding cubes for the accepted clustering seed candidate were generated and the overlapping cubes were combined and examined...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28244109/improvements-of-an-objective-model-of-compressed-breasts-undergoing-mammography-generation-and-characterization-of-breast-shapes
#13
Alejandro Rodríguez-Ruiz, Steve Si Jia Feng, Jan van Zelst, Suzan Vreemann, Jessica Rice Mann, Carl Joseph D'Orsi, Ioannis Sechopoulos
PURPOSE: To develop a set of accurate 2D models of compressed breasts undergoing mammography or breast tomosynthesis, based on objective analysis, to accurately characterize mammograms with few linearly independent parameters, and to generate novel clinically realistic paired cranio-caudal (CC) and medio-lateral oblique (MLO) views of the breast. METHODS: We seek to improve on an existing model of compressed breasts by overcoming detector size bias, removing the nipple and non-mammary tissue, pairing the CC and MLO views from a single breast, and incorporating the pectoralis major muscle contour into the model...
June 2017: Medical Physics
https://www.readbyqxmd.com/read/28226684/simplified-computer-aided-detection-scheme-of-microcalcification-clusters-in-digital-breast-tomosynthesis-images
#14
Ji-Wook Jeong, Seung-Hoon Chae, Eun Young Chae, Hak Hee Kim, Young Wook Choi, Sooyeul Lee, Ji-Wook Jeong, Seung-Hoon Chae, Eun Young Chae, Hak Hee Kim, Young Wook Choi, Sooyeul Lee, Sooyeul Lee, Ji-Wook Jeong, Hak Hee Kim, Eun Young Chae, Young Wook Choi, Seung-Hoon Chae
A computer-aided detection (CADe) algorithm for clustered microcalcifications (MCs) in reconstructed digital breast tomosynthesis (DBT) images is suggested. The MC-like objects were enhanced by a Hessian-based 3D calcification response function, and a signal-to-noise ratio (SNR) enhanced image was also generated to screen the MC clustering seed objects. A connected component segmentation method was used to detect the cluster seed objects, which were considered as potential clustering centers of MCs. Bounding cubes for the accepted clustering seed candidate were generated and the overlapping cubes were combined and examined...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28214227/automated-breast-density-computation-in-digital-mammography-and-digital-breast-tomosynthesis-influence-on-mean-glandular-dose-and-birads-density-categorization
#15
Maria Castillo-García, Margarita Chevalier, Julia Garayoa, Alejandro Rodriguez-Ruiz, Diego García-Pinto, Julio Valverde
RATIONALE AND OBJECTIVES: The study aimed to compare the breast density estimates from two algorithms on full-field digital mammography (FFDM) and digital breast tomosynthesis (DBT) and to analyze the clinical implications. MATERIALS AND METHODS: We selected 561 FFDM and DBT examinations from patients without breast pathologies. Two versions of a commercial software (Quantra 2D and Quantra 3D) calculated the volumetric breast density automatically in FFDM and DBT, respectively...
February 14, 2017: Academic Radiology
https://www.readbyqxmd.com/read/28192742/breast-cancer-detection-using-single-reading-of-breast-tomosynthesis-3d-mammography-compared-to-double-reading-of-2d-mammography-evidence-from-a-population-based-trial
#16
Nehmat Houssami, Daniela Bernardi, Marco Pellegrini, Marvi Valentini, Carmine Fantò, Livio Ostillio, Paolina Tuttobene, Andrea Luparia, Petra Macaskill
BACKGROUND: Most population breast cancer (BC) screening programs use double-reading of 2D-mammography. We recently reported the screening with tomosynthesis or standard mammography-2 (STORM-2) trial, showing that double-read tomosynthesis (pseudo-3D-mammography) detected more BC than double-read 2D-mammography. In this study, we compare screen-detection measures for single-reading of 3D-mammography with those for double-reading of 2D-mammography, to inform screening practice. METHODS: This is a secondary analysis based on STORM-2 which prospectively compared 3D-mammography and 2D-mammography in sequential screen-readings...
April 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/28112559/breast-radiation-dose-with-cesm-compared-with-2d-ffdm-and-3d-tomosynthesis-mammography
#17
COMPARATIVE STUDY
Judy R James, William Pavlicek, James A Hanson, Thomas F Boltz, Bhavika K Patel
OBJECTIVE: We aimed to compare radiation dose received during contrast-enhanced spectral mammography (CESM) using high- and low-energy projections with radiation dose received during 2D full field digital mammography (FFDM) and 3D tomosynthesis on phantoms and patients with varying breast thickness and density. MATERIALS AND METHODS: A single left craniocaudal projection was chosen to determine the doses for 6214 patients who underwent 2D FFDM, 3662 patients who underwent 3D tomosynthesis, and 173 patients who underwent CESM in this retrospective study...
February 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28107735/breast-cancers-detected-in-only-one-of-two-arms-of-a-tomosynthesis-3d-mammography-population-screening-trial-storm-2
#18
Daniela Bernardi, Nehmat Houssami
The prospective 'screening with tomosynthesis or standard mammography-2 (STORM-2)' trial compared mammography screen-reading strategies and showed that each of integrated 2D/3D-mammography or 2Dsynthetic/3D-mammography detected significantly more breast cancers than 2D-mammography alone. This short report describes 13 (from 90) cancers detected in only one of two parallel double-reading arms implemented in STORM-2. Amongst this subset of cases, the majority was invasive cancer ≤16 mm, mostly depicted as irregular masses or distortions...
April 2017: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/28072573/design-and-application-of-a-structured-phantom-for-detection-performance-comparison-between-breast-tomosynthesis-and-digital-mammography
#19
L Cockmartin, N W Marshall, G Zhang, K Lemmens, E Shaheen, C Van Ongeval, E Fredenberg, D R Dance, E Salvagnini, K Michielsen, H Bosmans
This paper introduces and applies a structured phantom with inserted target objects for the comparison of detection performance of digital breast tomosynthesis (DBT) against 2D full field digital mammography (FFDM). The phantom consists of a 48 mm thick breast-shaped polymethyl methacrylate (PMMA) container filled with water and PMMA spheres of different diameters. Three-dimensionally (3D) printed spiculated masses (diameter range: 3.8-9.7 mm) and non-spiculated masses (1.6-6.2 mm) along with microcalcifications (90-250 µm) were inserted as targets...
January 10, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28072394/three-dimensional-cascaded-system-analysis-of-a-50-%C3%A2%C2%B5m-pixel-pitch-wafer-scale-cmos-active-pixel-sensor-x-ray-detector-for-digital-breast-tomosynthesis
#20
C Zhao, N Vassiljev, A C Konstantinidis, R D Speller, J Kanicki
High-resolution, low-noise x-ray detectors based on the complementary metal-oxide-semiconductor (CMOS) active pixel sensor (APS) technology have been developed and proposed for digital breast tomosynthesis (DBT). In this study, we evaluated the three-dimensional (3D) imaging performance of a 50 µm pixel pitch CMOS APS x-ray detector named DynAMITe (Dynamic Range Adjustable for Medical Imaging Technology). The two-dimensional (2D) angle-dependent modulation transfer function (MTF), normalized noise power spectrum (NNPS), and detective quantum efficiency (DQE) were experimentally characterized and modeled using the cascaded system analysis at oblique incident angles up to 30°...
March 7, 2017: Physics in Medicine and Biology
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