Ziyaad Dangor, Nicole Benson, James A Berkley, Julia Bielicki, Merijn W Bijsma, Jonathan Broad, Ed T Buurman, Alan Cross, Erin M Duffy, Kathryn E Holt, Pui-Ying Iroh Tam, Mark Jit, Konstantinos Karampatsas, Michael Katwere, Gaurav Kwatra, Ramanan Laxminarayan, Kirsty Le Doare, Robert Mboizi, Francesca Micoli, Catrin E Moore, Eve Nakabembe, Nichola R Naylor, Seamus O'Brien, Courtney Olwagen, Denasha Reddy, Charlene Rodrigues, David A Rosen, Manish Sadarangani, Padmini Srikantiah, Sharon M Tennant, Mateusz Hasso-Agopsowicz, Shabir A Madhi
Klebsiella pneumoniae causes community- and healthcare-associated infections in children and adults. Globally in 2019, an estimated 1.27 million (95% Uncertainty Interval [UI]: 0.91-1.71) and 4.95 million (95% UI: 3.62-6.57) deaths were attributed to and associated with bacterial antimicrobial resistance (AMR), respectively. K. pneumoniae was the second leading pathogen in deaths attributed to AMR resistant bacteria. Furthermore, the rise of antimicrobial resistance in both community- and hospital-acquired infections is a concern for neonates and infants who are at high risk for invasive bacterial disease...
March 18, 2024: Vaccine