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Cervical dysplasia

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https://www.readbyqxmd.com/read/29679353/low-frequency-of-cervicocranial-artery-involvement-in-japanese-with-renal-artery-fibromuscular-dysplasia-compared-with-that-of-caucasians
#1
Eikan Mishima, Shu Umezawa, Takehiro Suzuki, Miki Fujimura, Michiaki Abe, Junichiro Hashimoto, Takaaki Abe, Sadayoshi Ito
BACKGROUND: Fibromuscular dysplasia (FMD), which usually affects the renal artery, also affects the carotid, vertebral, and intracranial arteries. Previous studies have shown a high prevalence of concomitant renal artery and cervicocranial lesions in FMD patients. However, the analyzed subjects were mostly Caucasians in Western countries. METHOD: We performed a retrospective analysis to examine the prevalence of cervicocranial vascular lesions in Japanese FMD patients with renal artery involvement at a single institution...
April 20, 2018: Clinical and Experimental Nephrology
https://www.readbyqxmd.com/read/29664878/c2-translaminar-screw-fixation-in-children
#2
Brian W Yang, Michael P Glotzbecker, Michael Troy, Mark R Proctor, Michael T Hresko, Daniel J Hedequist
BACKGROUND: Axis (C2) screw fixation has been shown to be effective in treating disorders that necessitate cervical stabilization. Although translaminar C2 screws have demonstrated clinical efficacy in adults, this technique has not yet been thoroughly investigated in children. This study describes the indications, technique, and results of translaminar C2 screw fixation in a case series of pediatric cervical spine disorders. METHODS: We searched the orthopaedic database at our institution for patients who had undergone a cervical spinal fusion that encompassed C2 between 2007 and 2017...
April 16, 2018: Journal of Pediatric Orthopedics
https://www.readbyqxmd.com/read/29627221/fluorescence-microscopy-of-h-e-stained-cervical-biopsies-to-assist-the-diagnosis-and-grading-of-cin
#3
REVIEW
Mario R Castellanos, Vijeyaluxmy Motilal Nehru, Edyta C Pirog, Lynne Optiz
BACKGROUND: Prevention of cervical cancer is based upon the accurate diagnosis and grading of cervical lesions identified during screening. The pathological classification of cervical intraepithelial neoplasia (CIN) is problematic, as it relies on subjective criteria and is known to have high interobserver variability and low reproducibility. These limitations can result in either over or under treatment of patients. Biomarkers to improve CIN diagnosis have not overcome all these challenges...
March 26, 2018: Pathology, Research and Practice
https://www.readbyqxmd.com/read/29611018/the-who-what-why-and-when-of-gynaecological-referrals-for-refugee-women
#4
Sarah L Silverberg, Lacey Harding, Rachel F Spitzer, Meb Rashid
Refugees have health needs relating to unstable living situations and poor access to care. We examined the nature of health problems requiring gynaecological referrals for refugee women in Toronto. A retrospective cohort design was used to examine gynaecologic referrals of women at a refugee clinic between December, 2011 and June, 2016. The primary outcome measure was the indications for gynaecological referral. 125 out of 1040 women received a gynaecologic referral for 131 unique concerns. The most common referrals were for abnormal uterine bleeding and cervical dysplasia...
April 2, 2018: Journal of Immigrant and Minority Health
https://www.readbyqxmd.com/read/29605043/an-educational-intervention-to-improve-human-papilloma-virus-hpv-and-cervical-cancer-knowledge-among-african-american-college-students
#5
Jeanine N Staples, Melissa S Wong, B J Rimel
OBJECTIVES: Misinformation and lack of formal education about cervical cancer may contribute to disparities. The objective of this study was to assess the role of an educational intervention in improving knowledge about Human papilloma virus (HPV) and cervical cancer among African American female college students. METHODS: We completed a total of 5 lectures at 4 different historically Black Colleges in North Carolina, Virginia, and West Virginia. Each 60min lecture reviewed basic female anatomy, HPV pathogenesis, cervical dysplasia, cervical cancer, HPV vaccination and cervical cancer screening...
April 2018: Gynecologic Oncology
https://www.readbyqxmd.com/read/29599374/natural-history-of-squamous-intraepithelial-lesions-in-pregnancy-and-mode-of-delivery
#6
Stefanie Schuster, Elmar Joura, Petra Kohlberger
BACKGROUND: Numerous studies have addressed the impact of mode of delivery on the natural history of squamous intraepithelial lesions (SIL) in pregnant women. However, the literature is still contradictory. PATIENTS AND METHODS: In the course of a retrospective analysis, data of 63 pregnant women with abnormal cervical smears who were referred to our Outpatient Department for pre-invasive lesions of the cervix were analyzed. The study was conducted at the General Hospital in Vienna, Austria, between 2010 and 2015...
April 2018: Anticancer Research
https://www.readbyqxmd.com/read/29587796/human-papilloma-virus-correlates-of-high-grade-cervical-dysplasia-in-hiv-infected-women-in-mombasa-kenya-a-cross-sectional-analysis
#7
Sonia Menon, Stanley Luchters, Rodolfo Rossi, Steven Callens, Mandaliya Kishor, Johannes Bogers, Davy Vanden Broeck
BACKGROUND: Women living with HIV are at increased risk to be co-infected with HPV, persistent high-risk (HR) human papillomavirus (HPV) infection and increased HR HPV viral load, which make them more at risk for cervical cancer. Despite their inherent vulnerability, there is a scarcity of data on potential high risk (pHR) and HR HPV genotypes in HIV- infected women with cervical dysplasia and HPV-type specific viral load in this population in Sub Saharan Africa. The aim of this analysis of HIV-infected women was to explore the virological correlates of high-grade cervical dysplasia (CIN 2+) in HIV-infected women, thereby profiling HPV genotypes...
March 27, 2018: Virology Journal
https://www.readbyqxmd.com/read/29581795/the-association-of-digit-ratio-2d-4d-with-cancer-a-systematic-review-and-meta-analysis
#8
REVIEW
Adomas Bunevicius
Objective: Intrauterine sex hormone environment as indicated by the second to the fourth digit ratio (2D : 4D) can be associated with cancer risk. This systematic review and meta-analysis aimed to evaluate the association of 2D : 4D with cancer diagnosis, malignancy, and age at presentation. Methods: Studies that evaluated the association of 2D : 4D with cancer risk were collected from Pubmed/MEDLINE and Clarivate Analytics databases. Nineteen studies were included in the qualitative analysis...
2018: Disease Markers
https://www.readbyqxmd.com/read/29527976/psychosexual-outcomes-in-women-of-reproductive-age-at-more-than-two-years-from-excisional-cervical-treatment-a-cross-sectional-study
#9
Radmila Sparić, Dimitrios Papoutsis, Saša Kadija, Radomir Stefanović, Angeliki Antonakou, Lazar Nejković, Vesna Kesić
PURPOSE: To investigate the long-term psychosexual outcomes in women following excisional cervical treatment. MATERIALS AND METHODS: Women with cold-knife conization (CKC) or large loop excision of the transformation zone (LLETZ) treatment were interviewed after a follow-up colposcopy visit. Their demographics, treatment and psychosexual characteristics were recorded. RESULTS: One hundred and forty six women with a mean age of 35.2 ± 5...
March 12, 2018: Journal of Psychosomatic Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/29516923/immunohistochemical-evaluation-of-prime-molecules-in-cervical-lesions-towards-assessment-of-malignant-potentiality
#10
Lopamudra Das, Sukla Naskar, Tandra Sarkar, Ashok Kumar Maiti, Soumen Das, Jyotirmoy Chatterjee
Objective: A comparative immunohistochemical evaluation of p63, CD105, and E-cadherin expression pattern in histopathologically confirmed normal cervical epithelium (NCM), dysplastic cervical epithelium (DYS) and squamous cell carcinoma (SCC) of uterine cervix towards assessing malignant potentiality of the precancerous condition. Materials and Methods: The biopsies from cervical mucosa (normal, dysplasia, and cancer) were studied by routine hematoxylin and eosin (H and E) and by immunohistochemistry for p63, E-cadherin, and CD105 expression...
January 2018: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/29504352/sprengel-s-deformity
#11
Muhammad Younus Khan Durrani, Amir Humza Sohail, Inamullah Khan, Pervaiz Hashmi
Various shoulder bone deformities have been identified in the pediatric age group, with the most common being undescended scapula. Sprengel's deformity is dysplasia and malposition of the scapula, especially in the supraspinatus portion, mainly due to abnormal descent in the embryonic period. The clavicle is shorter and has a different contour. In some patients cervical spine deformities are also noted. This is a case of 3 years old girl presented to the clinic with difficulty in abducting right shoulder and sleeping with an internal rotation of the right arm...
January 2018: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/29504143/a-case-report-of-ovotesticular-disorder-of-sex-development-ot-dsd-in-a-baboon-papio-spp-and-a-brief-review-of-the-non-human-primate-literature
#12
REVIEW
Ekaterina Perminov, Sara Mangosing, Alexandra Confer, Olga Gonzalez, Jason R Crawford, Natalia Schlabritz-Loutsevitch, Shyamesh Kumar, Edward Dick
Disorders of sexual development are rare in non-human primates. We report a case of true hermaphroditism in a 19-year-old, nulliparous, female baboon (Papio spp.). At necropsy, the animal was obese with adequate muscle mass and hydration. Reproductive organs appeared normal with the exception of 2 firm nodular structures in the myometrium (1-1.5 cm diameter) and a thickened, dark endocervical mucosa. Histologically, both gonads were ovotestes and contained discrete areas of ovarian and testicular tissue. There were follicles in various stages of development surrounded by ovarian stroma...
March 5, 2018: Journal of Medical Primatology
https://www.readbyqxmd.com/read/29489401/cervical-spine-injury-from-unrecognized-craniocervical-instability-in-severe-pierre-robin-sequence-associated-with-skeletal-dysplasia
#13
Xiao Zhu, Kelly N Evans, Areeg El-Gharbawy, Jonathan Y Lee, Jack E Brooker, Noel Jabbour, Elizabeth C Tyler-Kabara, Suneeta Madan-Khertarpal, Joseph E Losee, Jesse A Goldstein
Pierre Robin Sequence (PRS) can be associated with skeletal dysplasias, presenting with craniocervical instability and devastating spinal injury if unrecognized. The authors present the case of an infant with PRS and a type II collagenopathy who underwent multiple airway-securing procedures requiring spinal manipulation before craniocervical instability was identified. This resulted in severe cervical cord compression due to odontoid fracture and occipitoatlantoaxial instability. This case highlights the importance of early cervical spine imaging and cautious manipulation in infants with PRS and suspected skeletal dysplasia...
January 1, 2018: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/29488269/characteristic-findings-of-cervical-papanicolaou-tests-from-transgender-patients-on-androgen-therapy-challenges-in-detecting-dysplasia
#14
B D Adkins, A B Barlow, A Jack, S J Schultenover, M M Desouki, A C Coogan, V L Weiss
INTRODUCTION: The characteristic features of Papanicolaou (Pap) tests collected from female-to-male (FTM) transgender patients on androgen therapy have not been well defined in the literature. FTM transgender patients require cervical cancer screening with the same recommended frequency as cis-gender females. Dysplasia remains challenging to differentiate from atrophy. Without pertinent history, the atrophic findings in younger transgender patients can be misinterpreted as high-grade dysplasia...
February 28, 2018: Cytopathology: Official Journal of the British Society for Clinical Cytology
https://www.readbyqxmd.com/read/29474240/high-rates-of-high-grade-cervical-dysplasia-in-high-risk-young-women-with-low-grade-cervical-cytology
#15
Laura R Daily, Britt K Erickson, Daniel N Pasko, J Michael Straughn, Warner K Huh, Charles A Leath
OBJECTIVE: The aim of the study was to determine rates of cervical intraepithelial neoplasia (CIN) 2 or greater in high-risk, racially diverse, young women with low-grade cytology. MATERIALS AND METHODS: After institutional review board approval, a cross-sectional study of 21- to 24-year-old women with low-grade cytology (atypical squamous cells of undetermined significance, high-risk human papillomavirus+, low-grade squamous intraepithelial lesion, or human papillomavirus+ only) managed with colposcopy at our university-based clinic between May 2011 and April 2013 were identified...
February 23, 2018: Journal of Lower Genital Tract Disease
https://www.readbyqxmd.com/read/29474234/simple-hysterectomy-for-residual-cervical-intraepithelial-neoplasm
#16
Liat Binyamin, Meirav Segev, Yoav Peled, Haim Krissi, Gad Sabah, Oded Raban, Ariella Jakobson-Setton, Avi Ben-Haroush, Ram Eitan
OBJECTIVE: Many patients undergo hysterectomy for the treatment of cervical dysplasia. Factors that correlate with residual high-grade squamous intraepithelial lesions (HGSIL) at hysterectomy are not clear. We set out to determine preoperative features that may predict residual disease for patients treated for cervical dysplasia. MATERIALS AND METHODS: A retrospective database was reviewed for women who underwent simple hysterectomy for HGSIL between 1990 and 2013...
February 23, 2018: Journal of Lower Genital Tract Disease
https://www.readbyqxmd.com/read/29474233/expert-review-of-cervical-cytology-does-it-affect-patient-care
#17
Jaron Mark, Kayla Morrell, Kevin Eng, Alexandra Alfiero, Peter J Frederick
OBJECTIVES: The aim of the study was to evaluate whether expert review of outside cervical cytology affects patient care. MATERIALS AND METHODS: A retrospective study was conducted of 424 new patient referrals for cervical dysplasia between 2004 and 2016 at Roswell Park Cancer Institute. Records were analyzed for outside cervical cytology reports and compared with expert cervical cytology review. Differences between expert review and outside reports were documented...
February 23, 2018: Journal of Lower Genital Tract Disease
https://www.readbyqxmd.com/read/29460502/immediate-biopsy-of-cervical-cytology-negative-and-non-hpv-16-18-oncogenic-types-positive-patients
#18
İbrahim Karaca, Mustafa Öztürk, Cihan Comba, Gökhan Demirayak, İsmail Alay, Volkan Şakir Erdoğan, Murat Hoşgören, Levent Yaşar
BACKGROUND: According to the American Society of Colposcopy and Cervical Pathology (ASCCP), a co-test is recommended for patients one year after the detection of non-HPV 16/18 viral types in association with a negative cervical cytology. In this study, we used immediate colposcopy to evaluate the risks to the patient during the one year waiting period. METHODS: We included 544 Hpv-positive/cervical cytology-negative patients who underwent cervical cancer screening from June 2015 to June 2017...
April 2018: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/29451436/novel-posterior-artificial-atlanto-odontoid-joint-for-atlantoaxial-instability-a-biomechanical-study
#19
Kai Shen, Zhongliang Deng, Junsong Yang, Chao Liu, Ranxi Zhang
OBJECTIVE Atlantoaxial instability is usually corrected by anterior and/or posterior C1-2 fusion. However, fusion can lead to considerable loss of movement at the C1-2 level, which can adversely impact a patient's quality of life. In this study, the authors investigated the stability and function of a novel posterior artificial atlanto-odontoid joint (NPAAJ) by using cadaveric cervical spines. METHODS The Oc-C7 regions from 10 cadaveric spines were used for anteroposterior (AP) translation and range of motion (ROM) tests while intact and after destabilization, NPAAJ implantation, and double-rod fixation...
February 16, 2018: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/29430635/hpv-testing-vs-hpv-cytology-co-testing-to-predict-the-outcome-after-conization
#20
Laerke Valsøe Bruhn, Sisse Josephine Andersen, Jalil Hariri
INTRODUCTION: The purpose of this study was to determine the feasibility of human papillomavirus (HPV) testing alone as prognostic tool to predict recurrent disease within a three years follow-up period after treatment for cervical intraepithelial neoplasia (CIN)2+. MATERIAL AND METHODS: Retrospectively 128 women, with histologically verified CIN2+, who had a conization performed at Southern Jutland Hospital in Denmark between January 1st 2013 and December 31st 2013 were included...
February 11, 2018: Acta Obstetricia et Gynecologica Scandinavica
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