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https://www.readbyqxmd.com/read/29220826/time-distortion-when-users-at-risk-for-social-media-addiction-engage-in-non-social-media-tasks
#1
Ofir Turel, Damien Brevers, Antoine Bechara
BACKGROUND: There is a growing concern over the addictiveness of Social Media use. Additional representative indicators of impaired control are needed in order to distinguish presumed social media addiction from normal use. AIMS: (1) To examine the existence of time distortion during non-social media use tasks that involve social media cues among those who may be considered at-risk for social media addiction. (2) To examine the usefulness of this distortion for at-risk vs...
December 2, 2017: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/29220766/a-global-framework-to-model-spatial-ecosystems-exposure-to-home-and-personal-care-chemicals-in-asia
#2
Cedric Wannaz, Antonio Franco, John Kilgallon, Juliet Hodges, Olivier Jolliet
This paper analyzes spatially ecosystem exposure to home and personal care (HPC) chemicals, accounting for market data and environmental processes in hydrological water networks, including multi-media fate and transport. We present a global modeling framework built on ScenAT (spatial scenarios of emission), SimpleTreat (sludge treatment plants), and Pangea (spatial multi-scale multimedia fate and transport of chemicals), that we apply across Asia to four chemicals selected to cover a variety of applications, volumes of production and emission, and physico-chemical and environmental fate properties: the anionic surfactant linear alkylbenzene sulphonate (LAS), the antimicrobial triclosan (TCS), the personal care preservative methyl paraben (MeP), and the emollient decamethylcyclopentasiloxane (D5)...
December 5, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29220744/sensitive-detection-of-pyoverdine-with-an-electrochemical-sensor-based-on-electrochemically-generated-graphene-functionalized-with-gold-nanoparticles
#3
Islem Gandouzi, Mihaela Tertis, Andreea Cernat, Amina Bakhrouf, Maria Coros, Stela Pruneanu, Cecilia Cristea
The design and development of an electrochemical sensor for the sensitive and selective determination of pyoverdine, a virulence factor secreted by Pseudomonas aeruginosa, bacteria involved in nosocomial infections is presented in this work. The presence of pyoverdine in water and body fluids samples can be directly linked to the presence of the Pseudomonas bacteria, thus being a nontoxic and low cost marker for the detection of water pollution as well as for the biological contamination of other media. The sensor was elaborated using layer-by-layer technique for the deposition of a graphene‑gold nanoparticles composite film on the graphite-based screen printed electrode, from aqueous suspension...
December 5, 2017: Bioelectrochemistry
https://www.readbyqxmd.com/read/29220341/auditing-safety-of-compounding-and-reconstituting-of-intravenous-medicines-on-hospital-wards-in-finland
#4
Eeva Suvikas-Peltonen, Joni Palmgren, Verner Häggman, Ercan Celikkayalar, Raija Manninen, Marja Airaksinen
On the hospital wards in Finland, nurses generally reconstitute intravenous medicines, such as antibiotics, analgesics, and antiemetics prescribed by doctors. Medicine reconstitution is prone to many errors. Therefore, it is important to identify incorrect practices in the reconstitution of medicine to improve patient safety in hospitals. The aim of this study was to audit the compounding and reconstituting of intravenous medicines on hospital wards in a secondary-care hospital in Finland by using an assessment tool and microbiological testing for identifying issues posing patient safety risks...
November 2017: International Journal of Pharmaceutical Compounding
https://www.readbyqxmd.com/read/29220319/poi-summarization-by-aesthetics-evaluation-from-crowd-source-social-media
#5
Xueming Qian, Cheng Li, Ke Lan, Xingsong Hou, Zhetao Li, Junwei Han
Place-of-Interest (POI) summarization by aesthetics evaluation can recommend a set of POI images to the user and it is significant in image retrieval. In this paper, we propose a system that summarizes a collection of POI images regarding both aesthetics and diversity of the distribution of cameras. First, we generate visual albums by a coarse-to-fine POI clustering approach and then generate 3D models for each album by the collected images from social media. Second, based on the 3D to 2D projection relationship, we select candidate photos in terms of the proposed crowd source saliency model...
March 2018: IEEE Transactions on Image Processing: a Publication of the IEEE Signal Processing Society
https://www.readbyqxmd.com/read/29218249/pericellular-regulation-of-prostate-cancer-expressed-kallikrein-related-peptidases-and-matrix-metalloproteinases-by-cell-surface-serine-proteases
#6
Janet C Reid, Admire Matsika, Claire M Davies, Yaowu He, Amy Broomfield, Nigel C Bennett, Viktor Magdolen, Bhuvana Srinivasan, Judith A Clements, John D Hooper
We provide evidence of a pericellular network of proteases that are elevated and co-expressed in prostate cancer. The network involves the membrane bound serine proteases hepsin and TMPRSS2, the secreted kallikrein-related peptidases KLK4 and KLK14, and the secreted matrix metalloproteinases MMP-3 and MMP-9. Western blot analysis of cell lysates, conditioned cell culture media, immunoprecipitates and cell surface proteins, demonstrates a network of interactions centred largely at the plasma membrane, with the Arg/Lys specific proteases hepsin and TMPRSS2 key regulators of the network...
2017: American Journal of Cancer Research
https://www.readbyqxmd.com/read/29218108/the-synergistic-effect-of-esophageal-squamous-cell-carcinoma-kyse150-cells-and-m2-macrophages-on-lymphatic-endothelial-cells
#7
Miao-Miao Sun, Lu-Lu He, Hong-Xin Zhang, Na Wei, Wei-Wei Wang, Guo-Zhong Jiang, Zheng-Yang Wang, Dong-Mei Zhao, Kui-Sheng Chen
Objective: This study aimed to investigate whether tumor-associated macrophages (TAMs) and esophageal squamous cell carcinoma (ESCC) cells could synergistically influence the generation of lymphatic vessels via the VEGF-C/VEGFR-3 signaling pathway and to address its mechanism. Methods: M2 macrophages were sorted with immunomagnetic beads and induced in vitro. VEGF-C siRNA plasmids were constructed and transfected into M2 macrophages and the ESCC cell line KYSE150. Different conditioned culture media before and after transfection were collected and classified into different groups for culturing ESCC-associated lymphatic endothelial cells (ESCC-LECs)...
2017: American Journal of Translational Research
https://www.readbyqxmd.com/read/29217752/mapping-the-distribution-of-stem-progenitor-cells-across-the-middle-ear-during-homeostasis-and-inflammation
#8
Abigail S Tucker, Carlene J Dyer, Juan M Fons Romero, Tathyane H N Teshima, Jennifer C Fuchs, Hannah Thompson
The middle ear epithelium is derived from neural crest and endoderm, which line distinct regions of the middle ear cavity. Here we investigate the distribution of putative stem cell markers in the middle ear combined with an analysis of the location of label retaining cells (LRCs) to create a map of the middle ear mucosa. We show that proliferating cells and LRCs were associated with specific regions of the ear epithelium, concentrated in the hypotympanum at the base of the auditory bulla and around the ear drum...
December 7, 2017: Development
https://www.readbyqxmd.com/read/29217599/ers-statement-on-obstructive-sleep-disordered-breathing-in-1-to-23-month-old-children
#9
Athanasios G Kaditis, Maria Luz Alonso Alvarez, An Boudewyns, Francois Abel, Emmanouel I Alexopoulos, Refika Ersu, Koen Joosten, Helena Larramona, Silvia Miano, Indra Narang, Hui-Leng Tan, Ha Trang, Marina Tsaoussoglou, Nele Vandenbussche, Maria Pia Villa, Dick Van Waardenburg, Silke Weber, Stijn Verhulst
The present statement was produced by a European Respiratory Society Task Force to summarise the evidence and current practice on the diagnosis and management of obstructive sleep disordered breathing (SDB) in children aged 1-23 months. A systematic literature search was completed and 159 articles were summarised to answer clinically relevant questions. SDB is suspected when symptoms or abnormalities related to upper airway obstruction are identified. Morbidity (pulmonary hypertension, growth delay, behavioural problems) and coexisting conditions (feeding difficulties, recurrent otitis media) may be present...
December 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/29217390/food-and-beverage-tv-advertising-to-young-children-measuring-exposure-and-potential-impact
#10
Jennifer L Harris, Svetlana S Kalnova
Children of all ages are vulnerable to influence from exposure to unhealthy food advertisements, but experts raise additional concerns about children under 6 due to their more limited cognitive abilities. Most companies in the U.S. Children's Food and Beverage Advertising Initiative (CFBAI) industry self-regulatory program pledge to not direct any advertising to children under 6. However, young children also watch programming primarily directed to older children and thus may view food-related advertising despite companies' pledges...
December 4, 2017: Appetite
https://www.readbyqxmd.com/read/29217379/major-epidemiological-factors-associated-with-leptospirosis-in-malaysia
#11
REVIEW
Bashiru Garba, Abdul Rani Bahaman, Siti Khairani Bejo, Zunita Zakaria, Abdul Rahim Mutalib, Faruku Bande
INTRODUCTION: Leptospirosis is a zoonotic disease caused by a diverse pathogenic leptospira species and serovars. The disease is transmitted directly following contact with infected urine and other body fluids or indirectly after contact with water or soil contaminated with infected urine. OBJECTIVES: While a wide range of domestic and wild animals are known to be reservoirs of the disease, occupation, international travel and recreation are beginning to assume a center stage in the transmission of the disease...
December 4, 2017: Acta Tropica
https://www.readbyqxmd.com/read/29217310/about-the-connectivity-of-dual-scale-media-based-on-micro-structure-based-regional-analysis-of-nmr-flow-propagators
#12
Yong Zheng, Igor Shikhov, Louis Kpamsar Gbayan, Ji-Youn Arns, Christoph H Arns
The characterisation of heterogeneous porous media at multiple length scales typically requires the classification of structure at some scale to allow the calculation of effective transport properties at a scale relevant for macroscopic description. While such a classification may be derived from various imaging methods, a shortcoming is often the simultaneous characterisation of the connectivity between regions representing different micro-structure. In this work we combine NMR based flow propagators with the simulations performed on corresponding reconstructed structure, and relate the NMR measurements to their simulated global and local representations to study fluid transport locally and the exchange between micro- and macro-porous regions...
November 20, 2017: Journal of Contaminant Hydrology
https://www.readbyqxmd.com/read/29217114/identification-of-bacterial-uropathogens-by-preparative-isoelectric-focusing-and-maldi-tof-mass-spectrometry
#13
Jiří Šalplachta, Marie Horká, Filip Růžička, Karel Šlais
This study describes a new method for simultaneous identification of uropathogens in the case of polybacterial urinary tract infections. The method utilizes recently developed preparative isoelectric focusing (IEF) in cellulose-based separation medium with a subsequent analysis by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS). Preparative IEF was successfully used for both purification and separation of bacteria, Escherichia coli (pI 4.6) and Staphylococcus aureus (pI 3...
December 2, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/29216824/use-of-a-mixed-culture-strategy-to-isolate-halophilic-bacteria-with-antibacterial-and-cytotoxic-activity-from-the-manaure-solar-saltern-in-colombia
#14
Natalia Conde-Martínez, Alejandro Acosta-González, Luis E Díaz, Edisson Tello
BACKGROUND: Water evaporation in solar salterns creates salinity gradients that promote the adaptation of microbial species to different salinities. This competitive habitat challenges the metabolic capabilities of microorganisms and promotes alterations in their production of secondary metabolites. Thus, solar salterns are a potentially important source of new natural products. In Colombia, the most important and representative solar saltern is located in Manaure (La Guajira) in the north of Colombia...
December 8, 2017: BMC Microbiology
https://www.readbyqxmd.com/read/29216636/reduction-of-uterine-perfusion-pressure-induced-redistribution-of-endothelin-receptor-type-b-between-the-intima-and-media-contributes-to-the-pathogenesis-of-pregnancy-induced-hypertension
#15
Yuan Sun, Xicheng Zhang, Zhaolei Chen, Miao Xu, Minghui Ou
BACKGROUND/AIMS: Studies have shown that a change in endothelin receptor expression in the artery is related to pregnancy-induced hypertension (PIH). However, the mechanism underlying this change remains unclear. METHODS: To test whether the distribution of endothelin receptor type-A (ETAR) and type-B (ETBR) plays an important role in PIH, a reduction of uterine perfusion pressure (RUPP) rat model was used to mimic some of the features of PIH; the resulting variable endothelin receptor expression was investigated in the media and intima of the aorta...
December 6, 2017: Cellular Physiology and Biochemistry
https://www.readbyqxmd.com/read/29216618/kinetic-analysis-of-drug-release-from-compounded-slow-release-capsules-of-liothyronine-sodium-t3
#16
Hamid Bakhteyar, Clayton Cassone, Hamed Gilzad Kohan, Shabnam N Sani
The purpose of this study was to formulate extemporaneously compounded Liothyronine Sodium (T3) slow-release capsules and to evaluate their in vitro drug release performance. Twenty-one formulations containing T3 (7.5 µg) with various compositions of two different grades of Methocel E4M and K100M premium (30% to 90%), and/or SimpleCap/Lactose (10% to 70%) were examined. Quality assessment of the capsules was conducted by standard quality control criteria of the United States Pharmacopeia (i.e., weight variation, content uniformity) to ensure their compliance...
September 2017: International Journal of Pharmaceutical Compounding
https://www.readbyqxmd.com/read/29216587/quantification-of-immobilized-protein-in-pharmaceutical-production-by-bio-assisted-potentiometric-multisensor-system
#17
Edita Voitechovič, Anton Korepanov, Dmitry Kirsanov, Andrey Legin
Quantification of proteins is a key biochemical assay in molecular biology, biotechnology, medicine and pharmacology. Protein quantification protocols can be based on spectrophotometry, enzyme-linked immunosorbent assay, mass spectrometry or quantitative immunoblotting depending on analyte. In case of immobilized protein these methods require suitable sample preparation. Thus, sophisticated analysis becomes even more complex, expensive and time-consuming. Such drawbacks are highly undesirable in industry. In this study we propose a new approach for evaluation of immobilized protein concentration based on application of bio-assisted potentiometric multisensor system...
December 4, 2017: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/29216486/the-effects-of-microplastic-on-freshwater-hydra-attenuata-feeding-morphology-reproduction
#18
Fionn Murphy, Brian Quinn
Microplastic pollution has been a growing concern in the aquatic environment for several years. The abundance of microplastics in the environment has invariably led them to interact with a variety of different aquatic species. The small size of microplastics may make them bioavailable to a great range of species however, the impact this may have is not fully understood. Much of the research on microplastic pollution has focused on the marine environment and species with little research undertaken in freshwater...
December 4, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/29216280/phenotypic-characterization-of-synechocystis-sp-pcc-6803-substrains-reveals-differences-in-sensitivity-to-abiotic-stress
#19
Tomáš Zavřel, Petra Očenášová, Jan Červený
Synechocystis sp. PCC 6803 is a widely used model cyanobacterium, whose substrains can vary on both genotype and phenotype levels. Previously described phenotypic variations include ability of mixotrophic growth, ability of movement on agar plates and variations in pigments composition or cell size. In this study, we report for the first time significant variation among Synechocystis substrains in complex cellular traits such as growth rate, photosynthesis efficiency, cellular dry weight and cellular composition (including protein or carbohydrates content)...
2017: PloS One
https://www.readbyqxmd.com/read/29216210/social-relationship-changes-in-victim-families-due-to-a-social-disaster-experiences-of-student-victims-families-in-the-south-korean-sewol-ferry-disaster
#20
Sun Mi Cho, Ansuk Jeong, Jung Hee Ha, Eun Young Kim
The Sewol ferry incident on April 16, 2014 in South Korea claimed the lives of 304 individuals, including about 250 high school students on a school trip. The majority of South Korean citizens were watching live updates on the capsized Sewol ferry, anxiously watching on TV how the vessel fully sunk over time. They were desperately hoping for the rescue of the survivors inside. However, their anxiety had become shock, anger, and helplessness, and the disaster has become a daunting, collective trauma, not just to the victims and their families, but also to the citizens who were exposed only through the media...
2017: PloS One
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