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Breast biopsy

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https://www.readbyqxmd.com/read/28222244/breast-fna-biopsy-cytology-current-problems-and-the-international-academy-of-cytology-yokohama-standardized-reporting-system
#1
Andrew S Field
No abstract text is available yet for this article.
February 21, 2017: Cancer
https://www.readbyqxmd.com/read/28221191/the-assessment-of-estrogen-receptor-status-and-its-intratumoral-heterogeneity-in-breast-cancer-patients-by-using-18-f-fluoroestradiol-pet-ct
#2
Zhongyi Yang, Yifei Sun, Xiaoping Xu, Yongping Zhang, Jianping Zhang, Jing Xue, Mingwei Wang, Huiyu Yuan, Silong Hu, Wei Shi, Beiling Zhu, Yingjian Zhang
AIM: The aim of this study was to investigate the clinical value of F-fluoroestradiol (F-FES) PET/CT in the assessment of the estrogen receptor (ER) and its intratumoral heterogeneity in breast cancer patients. METHODS: Forty-six female patients (50 lesions) with histologically confirmed invasive breast cancer who underwent both F-FES and F-FDG PET/CT in our center were retrospectively included. All the patients enrolled were scheduled to undergo biopsy. The F-FES and FDG uptakes were compared with pathological features (tumor size, ER, progesterone receptor, human epidermal growth factor receptor 2, and Ki67%)...
February 17, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28220943/sonographic-appearance-of-a-cholesterol-granuloma-mimicking-breast-cancer
#3
Young-Seon Kim, Jung Min Chang
A breast cholesterol granuloma is a rare benign condition that can be a pitfall in diagnosing breast cancer. We describe a cholesterol granuloma in the breast mimicking breast cancer on sonography. The mass was confirmed to be a cholesterol granuloma through a core needle biopsy, but an excisional biopsy was eventually performed due to suspicious sonographic appearance and histopathological examination of the specimen confirmed the diagnosis. © 2017 Wiley Periodicals, Inc. J Clin Ultrasound, 2017.
February 21, 2017: Journal of Clinical Ultrasound: JCU
https://www.readbyqxmd.com/read/28218347/breast-cancer-early-diagnosis-and-effective-treatment-by-drug-delivery-tracing
#4
Mahdiyeh Shamsi, Jalil Pirayesh Islamian
Breast cancer is the most frequent cancer in women and it is the main reason of cancer-related deaths of women worldwide. Different types of breast cancer diagnostic examinations are also available, such as mammography, MRI, biopsy, ultrasound and molecular imaging. Radionuclide-based imaging methods including SPECT and PET are useful in early diagnosis and treatment of the cancer. The radiolabeling of chemo drugs with nanoparticles should be recommended from the standpoint of an early diagnosis and effective treatment of breast cancer...
2017: Nuclear Medicine Review. Central & Eastern Europe
https://www.readbyqxmd.com/read/28218293/plasma-exosome-profiling-of-cancer-patients-by-a-next-generation-systems-biology-approach
#5
Valeriy Domenyuk, Zhenyu Zhong, Adam Stark, Nianqing Xiao, Heather A O'Neill, Xixi Wei, Jie Wang, Teresa T Tinder, Sonal Tonapi, Janet Duncan, Tassilo Hornung, Andrew Hunter, Mark R Miglarese, Joachim Schorr, David D Halbert, John Quackenbush, George Poste, Donald A Berry, Günter Mayer, Michael Famulok, David Spetzler
Technologies capable of characterizing the full breadth of cellular systems need to be able to measure millions of proteins, isoforms, and complexes simultaneously. We describe an approach that fulfils this criterion: Adaptive Dynamic Artificial Poly-ligand Targeting (ADAPT). ADAPT employs an enriched library of single-stranded oligodeoxynucleotides (ssODNs) to profile complex biological samples, thus achieving an unprecedented coverage of system-wide, native biomolecules. We used ADAPT as a highly specific profiling tool that distinguishes women with or without breast cancer based on circulating exosomes in their blood...
February 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28217652/is-there-any-correlation-between-magnetic-resonance-imaging-features-of-breast-lesions-of-birads-category-4-with-histopathologic-results
#6
Maryam Farghadani, Ghazale Jamalipoor Soofi, Amir Hossein Sarrami
BACKGROUND: To evaluate the correlation of magnetic resonance imaging (MRI) features of breast lesions of Breast Imaging Reporting and Database System (BI-RADS) category 4 with histopathologic results. MATERIALS AND METHODS: In a prospective study between December 2013 and April 2015, patients with suspicious mammographic and/or ultrasound findings referred for Breast MRI were evaluated. Patients with lesions of BI-RADS category 4 were enrolled with a written informed consent...
2017: Advanced Biomedical Research
https://www.readbyqxmd.com/read/28217404/initial-experience-with-a-cone-beam-breast-computed-tomography-guided-biopsy-system
#7
Posy J Seifert, Renee C Morgan, David L Conover, Andrea L Arieno
OBJECTIVE: To evaluate our initial experience with a cone-beam breast computed tomography (BCT)-guided breast biopsy system for lesion retrieval in phantom studies for use with a cone-beam BCT imaging system. MATERIALS AND METHODS: Under the Institutional Review Board approval, a phantom biopsy study was performed using a dedicated BCT-guided biopsy system. Fifteen biopsies were performed on each of the small, medium, and large anthropomorphic breast phantoms with both BCT and stereotactic guidance for comparison...
2017: Journal of Clinical Imaging Science
https://www.readbyqxmd.com/read/28215506/radial-scar-of-the-breast-is-it-possible-to-avoid-surgery
#8
A I Ferreira, S Borges, A Sousa, C Ribeiro, A Mesquita, P C Martins, M Peyroteo, N Coimbra, C Leal, P Reis, J A Sousa
INTRODUCTION: Breast radial scar (RS) management remains controversial. The need for surgical excision is supported by the concern of an associated high-grade lesion missed in the biopsy. The aim of this study was to assess histologic upgrade rate after a percutaneous biopsy, to determine if vacuum assisted biopsy prevents the need for subsequent RS surgical resection and to evaluate the upgrade risk factors. PATIENTS AND METHODS: This was a uni-institutional retrospective study of consecutive patients with RS histologically diagnosed from January 2010 to December 2015...
February 3, 2017: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28214005/-review-of-national-and-international-guidelines-for-sentinel-lymph-node-biopsy-and-complementary-axillary-dissection-in-breast-cancer
#9
REVIEW
Laura Vincent, François Margueritte, Jennifer Uzan, Clémentine Owen, Julien Seror, Nicolas Pouget, Eugénie Guillot, Roman Rouzier
Management of breast cancer is based on national and international guidelines. These are defined on evidence-based medicine. The main purpose of this review is to compare the different guidelines for sentinel lymph node biopsy and completion axillary dissection after positive sentinel lymph node biopsy. This review of breast cancer guidelines led to identify consensus, but in some specific situations, they differ. The guidelines cannot be applied to all clinical cases, mandatoring multidisciplinary meetings are essential...
February 14, 2017: Bulletin du Cancer
https://www.readbyqxmd.com/read/28213790/optical-see-through-cancer-vision-goggles-enable-direct-patient-visualization-and-real-time-fluorescence-guided-oncologic-surgery
#10
Suman B Mondal, Shengkui Gao, Nan Zhu, LeMoyne Habimana-Griffin, Walter J Akers, Rongguang Liang, Viktor Gruev, Julie Margenthaler, Samuel Achilefu
BACKGROUND: The inability to visualize the patient and surgical site directly, limits the use of current near infrared fluorescence-guided surgery systems for real-time sentinel lymph node biopsy and tumor margin assessment. METHODS: We evaluated an optical see-through goggle augmented imaging and navigation system (GAINS) for near-infrared, fluorescence-guided surgery. Tumor-bearing mice injected with a near infrared cancer-targeting agent underwent fluorescence-guided, tumor resection...
February 17, 2017: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/28213781/swedish-prospective-multicenter-trial-on-the-accuracy-and-clinical-relevance-of-sentinel-lymph-node-biopsy-before-neoadjuvant-systemic-therapy-in-breast-cancer
#11
Linda Zetterlund, Fuat Celebioglu, Rimma Axelsson, Jana de Boniface, Jan Frisell
PURPOSE: The timing of sentinel lymph node biopsy (SLNB) in the context of neoadjuvant systemic therapy (NAST) in breast cancer is still controversial. SLNB before NAST has been evaluated in few single-institution studies in which axillary lymph node dissection (ALND), however, was commonly not performed in case of a negative SLNB. We investigated the potential clinical relevance of SLNB before NAST by performing ALND in all patients after NAST. METHODS: This national multicenter trial prospectively enrolled clinically node-negative breast cancer patients planned for NAST at 13 recruiting Swedish hospitals between October 2010 and December 2015...
February 17, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28213554/hypoxia-selectively-enhances-integrin-receptor-expression-to-promote-metastasis
#12
Julia A Ju, Ines Godet, I Chae Ye, Jungmin Byun, Hasini Jayatilaka, Sun Joo Lee, Lisha Xiang, Debangshu Samanta, Meng Horng Lee, Pei-Hsun Wu, Denis Wirtz, Gregg L Semenza, Daniele M Gilkes
: Metastasis is the leading cause of breast cancer (BCa)mortality. Previous studies have implicated hypoxia-induced changes in the composition and stiffness of the extracellular matrix (ECM) in the metastatic process. Therefore, the contribution of potential ECM binding receptors in this process was explored. Using a bioinformatics approach the expression of all integrin receptor subunits, in two independent BCa patient data sets, were analyzed to determine if integrin status correlates with a validated hypoxiainducible gene signature...
February 17, 2017: Molecular Cancer Research: MCR
https://www.readbyqxmd.com/read/28211807/two-dimensional-shear-wave-elastography-of-breast-lesions-comparison-of-two-different-systems
#13
Wei-Wei Ren, Xiao-Long Li, Ya-Ping He, Dan-Dan Li, Dan Wang, Chong-Ke Zhao, Xiao-Wan Bo, Bo-Ji Liu, Wen-Wen Yue, Hui-Xiong Xu
OBJECTIVE: To evaluate the diagnostic performance of two different shear wave elastography (SWE) techniques in distinguishing malignant breast lesions from benign ones. MATERIALS AND METHODS: From March 2016 to May 2016, a total of 153 breast lesions (mean diameter, 16.8 mm±10.5; range 4.1-90.0 mm) in 153 patients (mean age, 46.4 years±15.1; age range 20-86 years) were separately performed by two different SWE techniques (i.e. T-SWE, Aplio500, Toshiba Medical System, Tochigi, Japan; and S-SWE, the Aixplorer US system, SuperSonic Imagine, Provence, France)...
February 17, 2017: Clinical Hemorheology and Microcirculation
https://www.readbyqxmd.com/read/28210560/sinusoidal-hemangioma-of-the-breast-diagnostic-evaluation-management-and-literature-review
#14
Nikolaos S Salemis
Vascular tumors of the breast are rare and may pose a diagnostic challenge. Breast hemangioma is a very rare benign vascular neoplasm accounting for 0.4% of all breast tumors. It is most commonly detected as an incidental microscopic finding in biopsy specimens obtained for unrelated reasons. We describe here a very rare case of a sinusoidal breast hemangioma in a postmenopausal patient who presented with a palpable breast mass. A complete surgical resection was performed because the tumor exhibited atypical imaging features...
February 2017: Gland Surgery
https://www.readbyqxmd.com/read/28208973/shear-wave-elastography-features-of-primary-non-hodgkin-s-lymphoma-of-the-breast-a-case-report-and-literature-review
#15
Youdong Kim, Kyung Hee Ko, Hae Kyoung Jung, Hyun Ju Lee
Lymphoma is a rare malignancy of the breast, comprising approximately 0.04 to 0.5% of breast malignancies. Because the clinical findings of breast lymphoma are nonspecific and similar to those of breast carcinoma, it is important to distinguish breast lymphoma from other breast disease on the basis of radiologic findings. Elastography is an interesting imaging tool that reflects the tissue stiffness, increasingly being used in the evaluation of breast tumours. However, only a limited number of studies have focused on the elastographic findings of breast lymphoma...
December 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28208771/detecting-blood-based-biomarkers-in-metastatic-breast-cancer-a-systematic-review-of-their-current-status-and-clinical-utility
#16
REVIEW
A M Sofie Berghuis, Hendrik Koffijberg, Jai Prakash, Leon W M M Terstappen, Maarten J IJzerman
Reviews on circulating biomarkers in breast cancer usually focus on one single biomarker or a selective group of biomarkers. An overview summarizing the discovery and evaluation of all blood-based biomarkers in metastatic breast cancer is lacking. This systematic review aims to identify the available evidence of known blood-based biomarkers in metastatic breast cancer, regarding their clinical utility and state-of-the-art position in the validation process. The initial search yielded 1078 original studies, of which 420 were assessed for eligibility...
February 9, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28207201/diagnostic-yield-of-cytopathology-in-evaluating-pericardial-effusions-clinicopathologic-analysis-of-419-specimens
#17
Jad Saab, Rana S Hoda, Navneet Narula, Syed A Hoda, Brian E Geraghty, Abu Nasar, Susan A Alperstein, Jeffrey L Port, Tamar Giorgadze
BACKGROUND: Pericardial effusions can cause considerable morbidity and potentially may lead to mortality. Malignant pericardial effusions are uncommon, and data on malignancies encountered in pericardial effusion cytology specimens are limited. METHODS: Relevant records of all pericardial effusions from January 2008 to September 2014 were examined and compared with pericardial biopsy results when performed. Discrepant cases were reviewed to determine the cause of the disagreement...
February 2017: Cancer
https://www.readbyqxmd.com/read/28203179/malignant-phyllodes-tumor-presenting-in-bone-brain-lungs-and-lymph-nodes
#18
Eric D Johnson, Evin Gulbahce, Joseph McNally, Saundra S Buys
INTRODUCTION: Phyllodes tumors (PTs) are rare fibroepithelial tumors of the breast which are classified as benign, borderline, or malignant. Malignant PTs account for <1% of malignant breast tumors, and borderline tumors have potential to progress to malignant tumors. Metastatic recurrences are most commonly documented in bone and lungs. We report an extremely rare presentation of recurrent malignant PTs involving the brain, lung, lymph nodes, and bone. CASE: A 66-year-old female presented with a large breast mass...
September 2016: Case Reports in Oncology
https://www.readbyqxmd.com/read/28202253/flap-fixation-using-tissue-glue-or-sutures-appears-to-reduce-seroma-aspiration-after-mastectomy-for-breast-cancer
#19
James van Bastelaar, Lotte L B Theunissen, Maarten G J Snoeijs, Geerard L Beets, Yvonne L J Vissers
BACKGROUND: Up to 90% of patients undergoing breast cancer surgery suffer from seroma formation, which can cause discomfort and various complications after mastectomy. This retrospective observational cohort study aimed to elucidate whether flap fixation with fibrin sealant (ARTISS) tissue glue reduces seroma formation and seroma aspiration after mastectomy when compared with flap fixation using Vicryl sutures and when compared with a conventional wound closure technique. METHODS: All patients undergoing mastectomy due to invasive breast cancer or ductal carcinoma in situ were eligible for inclusion...
January 24, 2017: Clinical Breast Cancer
https://www.readbyqxmd.com/read/28199139/feasibility-of-vacuum-assisted-breast-cone-beam-ct-guided-biopsy-and-comparison-with-prone-stereotactic-biopsy
#20
Susanne Wienbeck, Joachim Lotz, Uwe Fischer
OBJECTIVE: The feasibility of breast vacuum-assisted biopsy (VAB) guided by cone-beam CT (CBCT) was assessed. The initial clinical performance of CT-guided breast VAB was compared with that of established prone stereotactic VAB. MATERIALS AND METHODS: In this retrospective clinical trial, VABs were performed for women with mammographically suspicious breast lesions using a dedicated breast CBCT protocol. The technical success rate, total intervention time, and complications were documented and compared with examinations performed by prone stereotactic VAB...
February 15, 2017: AJR. American Journal of Roentgenology
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