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https://www.readbyqxmd.com/read/28447471/how-does-video-interaction-guidance-contribute-to-infant-and-parental-mental-health-and-well-being
#1
Hilary Kennedy, Kevin Ball, Jane Barlow
This article describes the contribution of video interaction guidance (VIG) to the development of infant and parental and VIG practitioners' mental health and well-being. The theoretical core of VIG was depicted in terms of concepts such as intersubjectivity, attunement and mediated learning. The way the VIG principles alongside the underpinning values and beliefs promote a process of attunement between parent and infant, the VIG practitioner and parent, and the VIG practitioner and supervisor is described...
April 1, 2017: Clinical Child Psychology and Psychiatry
https://www.readbyqxmd.com/read/28441181/inhaled-treprostinil-drug-delivery-during-mechanical-ventilation-and-spontaneous-breathing-using-two-different-nebulizers
#2
Donna K Parker, Shuijie Shen, Jiang Zheng, D Dunbar Ivy, Dave N Crotwell, Justin C Hotz, Robert M DiBlasi
OBJECTIVES: To determine the feasibility of delivering inhaled treprostinil during mechanical ventilation and spontaneous unassisted ventilation using the Tyvaso Inhalation System and the vibrating mesh nebulizer. We sought to compare differences in fine particle fraction, and absolute inhaled treprostinil mass delivered to neonatal, pediatric, and adult models affixed with a face mask, conventional, and high-frequency ventilation between Tyvaso Inhalation System and with different nebulizer locations between Tyvaso Inhalation System and vibrating mesh nebulizer...
April 22, 2017: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/28438438/-multiple-cephalic-deep-granuloma-annulare-of-children
#3
A Bulinckx, N Cambier, L Wayllace Gaspar, I Théate, P P Roquet-Gravy, D Bessis
BACKGROUND: Deep granuloma annulare is a fairly rare variety of granuloma annulare. It is seen predominantly in children and mainly affects the anterior aspect of the legs and the top of the feet; cephalic presentation is rare. Below, we report three cases of deep granuloma annulare in children presenting solely at the cephalic extremity. PATIENTS AND METHODS: Case 1: a six-year-old boy presented 7 cutaneous nodules measuring 1 to 2cm that were flesh-coloured, insensitive to palpation, of hard consistency and deeply attached...
April 21, 2017: Annales de Dermatologie et de Vénéréologie
https://www.readbyqxmd.com/read/28435022/maternal-separation-induced-hippocampal-changes-in-cadherin-1-cdh-1-mrna-and-on-recognition-memory-in-adolescent-mice
#4
Lucas Araújo de Azeredo, Luis Eduardo Wearick-Silva, Thiago Wendt Viola, Saulo Gantes Tractenberg, Anderson Centeno da Silva, Rodrigo Orso, Nadja Schröder, Timothy William Bredy, Rodrigo Grassi-Oliveira
In rodents, disruption of mother-infant attachment induced by maternal separation (MS) is associated with recognition memory impairment and long-term neurobiological consequences. Particularly stress-induced modifications have been associated to disruption of cadherin (CDH) adhesion function, which plays an important role in remodeling of neuronal connection and synaptic plasticity. This study investigated the sex-dependent effect of MS on recognition memory and mRNA levels of classical type I and type II CDH and the related β -catenin (β -Cat) in the hippocampus and prefrontal cortex of late adolescent mice...
April 20, 2017: Neurobiology of Learning and Memory
https://www.readbyqxmd.com/read/28431269/oxytocin-in-the-postnatal-period-associations-with-attachment-and-maternal-caregiving
#5
Jane Kohlhoff, Valsamma Eapen, Mark Dadds, Feroza Khan, Derrick Silove, Bryanne Barnett
BACKGROUND: This study investigated the associations of maternal oxytocin, self-reported attachment insecurity and depressive symptoms with maternal caregiving sensitivity at 3-4months postpartum, observed during the 'free play' and 'reunion' episodes of the Still Face Procedure. METHODS: 112 mothers completed questionnaires and gave blood samples to determine oxytocin plasma levels before (time 1) and after participating in the Still Face Procedure with their infant (time 2)...
March 27, 2017: Comprehensive Psychiatry
https://www.readbyqxmd.com/read/28425591/reflective-functioning-and-personality-organization-associations-with-negative-maternal-behaviors
#6
Karin Ensink, Marie-Eve Rousseau, Marko Biberdzic, Michaël Bégin, Lina Normandin
The aim of this study was to examine whether mothers who manifest insensitive and disconnected behaviors in interaction with their infants differ in terms of maternal reflective functioning (RF), personality organization, and histories of abuse. A total of 86 mother-infant dyads, 28 of them with histories of abuse, participated in the study. RF was assessed with the Adult Attachment Interview (C. George, N. Kaplan, & M. Main, 1985), and personality organization was assessed with the self-report Inventory of Personality Organization (M...
April 20, 2017: Infant Mental Health Journal
https://www.readbyqxmd.com/read/28416666/drebrin-restricts-rotavirus-entry-by-inhibiting-dynamin-mediated-endocytosis
#7
Bin Li, Siyuan Ding, Ningguo Feng, Nancie Mooney, Yaw Shin Ooi, Lili Ren, Jonathan Diep, Marcus R Kelly, Linda L Yasukawa, John T Patton, Hiroyuki Yamazaki, Tomoaki Shirao, Peter K Jackson, Harry B Greenberg
Despite the wide administration of several effective vaccines, rotavirus (RV) remains the single most important etiological agent of severe diarrhea in infants and young children worldwide, with an annual mortality of over 200,000 people. RV attachment and internalization into target cells is mediated by its outer capsid protein VP4. To better understand the molecular details of RV entry, we performed tandem affinity purification coupled with high-resolution mass spectrometry to map the host proteins that interact with VP4...
April 17, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28414546/behavioral-parent-training-in-infancy-what-about-the-parent-infant-relationship
#8
Angela M Blizzard, Nicole E Barroso, Francisco G Ramos, Paulo A Graziano, Daniel M Bagner
Behavioral parent training (BPT) and attachment interventions have demonstrated efficacy in improving outcomes for young children. Despite theoretical overlap in these approaches, the literature has evolved separately, particularly with respect to outcome measurement in BPT. We examined the impact of the Infant Behavior Program (IBP), a brief home-based adaptation of Parent-Child Interaction Therapy, on changes in attachment-based caregiving behaviors (sensitivity, warmth, and intrusiveness) at postintervention and 3- and 6-month follow-ups during a videotaped infant-led play...
April 17, 2017: Journal of Clinical Child and Adolescent Psychology
https://www.readbyqxmd.com/read/28412510/empathy-networks-in-the-parental-brain-and-their-long-term-effects-on-children-s-stress-reactivity-and-behavior-adaptation
#9
Eyal Abraham, Gal Raz, Orna Zagoory-Sharon, Ruth Feldman
Parental empathy is a key component of sensitive parenting that supports children's social adaptation throughout life. Consistent with a two dissociable network perspective on empathy, we measured within- and between-network integrity of two empathy-related networks in the parental brain as predictors of children's social outcomes across the first six years of life. We focused on two empathy networks; embodied simulation, which supports parents' capacity to resonate with infant state and emotions and implicates cingulo-insulary structures, and mentalizing, which underpins parents' theory-of-mind and mental attributions via prefrontal-temporo-parietal circuit...
April 13, 2017: Neuropsychologia
https://www.readbyqxmd.com/read/28412066/ranibizumab-injection-as-primary-treatment-in-patients-with-retinopathy-of-prematurity-anatomic-outcomes-and-influencing-factors
#10
Qiujing Huang, Qi Zhang, Ping Fei, Yu Xu, Jiao Lyu, Xunda Ji, Jie Peng, Yi-An Li, Peiquan Zhao
PURPOSE: To investigate the anatomic outcomes and influencing factors of ranibizumab in the treatment of retinopathy of prematurity (ROP). DESIGN: Retrospective case series. PARTICIPANTS: A total of 283 eyes of 145 patients with type 1 ROP treated with intravitreal injection of ranibizumab (IVR) as primary treatment. METHODS: Retrospective review of infants who were diagnosed with type 1 ROP and accepted IVR (0.25 mg/0...
April 12, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28403682/the-ububele-baby-mat-service-a-primary-preventative-mental-health-intervention-in-a-culturally-diverse-setting
#11
N Dawson, J Richards, K Frost
The Ububele Baby Mat Service is a community-based, parent-infant mental health intervention offered at five primary health care clinics in Alexandra Township, in Johannesburg. The aim of the intervention is to promote healthy caregiver-infant attachments. There has been a steady increase in the number of mother-baby dyads making use of the service. This paper aims to explore how the Baby Mat Service and Baby Mat practitioners position and locate themselves in a culturally diverse community setting where multiple meaning systems are drawn on for making sense of health concerns...
April 13, 2017: Journal of Child and Adolescent Mental Health
https://www.readbyqxmd.com/read/28401851/assessing-a-change-mechanism-in-a-randomized-home-visiting-trial-reducing-disrupted-maternal-communication-decreases-infant-disorganization
#12
Susana Tereno, Sheri Madigan, Karlen Lyons-Ruth, Andre Plamondon, Leslie Atkinson, Nicole Guedeney, Tim Greacen, Romain Dugravier, Thomas Saias, Antoine Guedeney
Although randomized interventions trials have been shown to reduce the incidence of disorganized attachment, no studies to date have identified the mechanisms of change responsible for such reductions. Maternal sensitivity has been assessed in various studies and shown to change with intervention, but in the only study to formally assess mediation, changes in maternal sensitivity did not mediate changes in infant security of attachment (Cicchetti, Rogosch, & Toth, 2006). Primary aims of the current randomized controlled intervention trial in a high-risk population were to fill gaps in the literature by assessing whether the intervention (a) reduced disorganization, (b) reduced disrupted maternal communication, and (c) whether reductions in disrupted maternal communication mediated changes in infant disorganization...
May 2017: Development and Psychopathology
https://www.readbyqxmd.com/read/28401849/developmental-cascade-effects-of-interpersonal-psychotherapy-for-depressed-mothers-longitudinal-associations-with-toddler-attachment-temperament-and-maternal-parenting-efficacy
#13
Elizabeth D Handley, Louisa C Michl-Petzing, Fred A Rogosch, Dante Cicchetti, Sheree L Toth
Using a developmental cascades framework, the current study investigated whether treating maternal depression via interpersonal psychotherapy (IPT) may lead to more widespread positive adaptation for offspring and mothers including benefits to toddler attachment and temperament, and maternal parenting self-efficacy. The participants (N = 125 mother-child dyads; mean mother age at baseline = 25.43 years; 54.4% of mothers were African American; mean offspring age at baseline = 13.23 months) were from a randomized controlled trial of IPT for a sample of racially and ethnically diverse, socioeconomically disadvantaged mothers of infants...
May 2017: Development and Psychopathology
https://www.readbyqxmd.com/read/28401846/proof-of-concept-of-a-mind-mindedness-intervention-for-mothers-hospitalized-for-severe-mental-illness
#14
Robin Schacht, Elizabeth Meins, Charles Fernyhough, Luna C M Centifanti, Jean-François Bureau, Susan Pawlby
Studies 1 and 2 investigated how maternal severe mental illness (SMI) related to mothers' mind-mindedness (appropriate and nonattuned mind-related comments). Study 1 showed that mothers with SMI (n = 50) scored lower than psychologically well mothers for both appropriate and nonattuned comments, whereas mothers with SMI in Study 2 (n = 22) had elevated levels of nonattuned comments. Study 2 also tested the efficacy of a single-session video-feedback intervention to facilitate mind-mindedness in mothers with SMI...
May 2017: Development and Psychopathology
https://www.readbyqxmd.com/read/28401842/testing-the-limits-extending-attachment-based-intervention-effects-to-infant-cognitive-outcome-and-parental-stress
#15
Karine Dubois-Comtois, Chantal Cyr, George M Tarabulsy, Diane St-Laurent, Annie Bernier, Ellen Moss
Using a sample of 41 infants and toddlers (21 interventions, 20 controls) who were neglected or at serious risk for neglect, this randomized clinical trial examined the efficacy of a parent-child attachment-based video-feedback intervention on parental sensitivity, parental stress, and child mental/psychomotor development. Results showed that following the 8-week intervention, scores for maternal sensitivity and child mental and psychomotor development were higher in the intervention group than in the control group...
May 2017: Development and Psychopathology
https://www.readbyqxmd.com/read/28401840/methylation-matters-fk506-binding-protein-51-fkbp5-methylation-moderates-the-associations-of-fkbp5-genotype-and-resistant-attachment-with-stress-regulation
#16
Rosa H Mulder, Jolien Rijlaarsdam, Maartje P C M Luijk, Frank C Verhulst, Janine F Felix, Henning Tiemeier, Marian J Bakermans-Kranenburg, Marinus H Van Ijzendoorn
The parent-child attachment relationship plays an important role in the development of the infant's stress regulation system. However, genetic and epigenetic factors such as FK506 binding protein 51 (FKBP5) genotype and DNA methylation have also been associated with hypothalamus-pituitary-adrenal axis functioning. In the current study, we examined how parent-child dyadic regulation works in concert with genetic and epigenetic aspects of stress regulation. We study the associations of attachment, extreme maternal insensitivity, FKBP5 single nucleotide polymorphism 1360780, and FKBP5 methylation, with cortisol reactivity to the Strange Situation Procedure in 298 14-month-old infants...
May 2017: Development and Psychopathology
https://www.readbyqxmd.com/read/28401837/new-insight-on-intergenerational-attachment-from-a-relationship-based-analysis
#17
Heidi N Bailey, George M Tarabulsy, Greg Moran, David R Pederson, Sandi Bento
Research on attachment transmission has focused on variable-centered analyses, where hypotheses are tested by examining linear associations between variables. The purpose of this study was to apply a relationship-centered approach to data analysis, where adult states of mind, maternal sensitivity, and infant attachment were conceived as being three components of a single, intergenerational relationship. These variables were assessed in 90 adolescent and 99 adult mother-infant dyads when infants were 12 months old...
May 2017: Development and Psychopathology
https://www.readbyqxmd.com/read/28401835/brain-activity-and-infant-attachment-history-in-young-men-during-loss-and-reward-processing
#18
Karina Quevedo, Theodore E A Waters, Hannah Scott, Glenn I Roisman, Daniel S Shaw, Erika E Forbes
There is now ample evidence that the quality of early attachment experiences shapes expectations for supportive and responsive care and ultimately serves to scaffold adaptation to the salient tasks of development. Nonetheless, few studies have identified neural mechanisms that might give rise to these associations. Using a moderately large sample of low-income male participants recruited during infancy (N = 171), we studied the predictive significance of attachment insecurity and disorganization at age 18 months (as measured in the Strange Situation Procedure) for patterns of neural activation to reward and loss at age 20 years (assessed during a reward-based task as part of a functional magnetic resonance imaging scan)...
May 2017: Development and Psychopathology
https://www.readbyqxmd.com/read/28384263/universal-vaccine-against-respiratory-syncytial-virus-a-and-b-subtypes
#19
Jeong-Yoon Lee, Jun Chang
Respiratory syncytial virus (RSV) is a major cause of acute lower respiratory tract infection in infants, young children, and the elderly. Two subtypes of RSV, A and B, circulate alternately at 1-2-year intervals during epidemics. The attachment glycoprotein (G protein) of RSV is one of the major targets for immune responses. In this study, we generated a recombinant fusion protein, GcfAB, which consists of the central regions (a.a. residues 131-230) of the G proteins of both RSV A (A2 strain) and B (B1 strain) subtypes, and investigated immunogenicity, protective efficacy, and immunopathology...
2017: PloS One
https://www.readbyqxmd.com/read/28360846/stress-and-the-emerging-roles-of-chromatin-remodeling-in-signal-integration-and-stable-transmission-of-reversible-phenotypes
#20
REVIEW
Ian C G Weaver, Austin C Korgan, Kristen Lee, Ryan V Wheeler, Amos S Hundert, Donna Goguen
The influence of early life experience and degree of parental-infant attachment on emotional development in children and adolescents has been comprehensively studied. Structural and mechanistic insight into the biological foundation and maintenance of mammalian defensive systems (metabolic, immune, nervous and behavioral) is slowly advancing through the emerging field of developmental molecular (epi)genetics. Initial evidence revealed that differential nurture early in life generates stable differences in offspring hypothalamic-pituitary-adrenal (HPA) regulation, in part, through chromatin remodeling and changes in DNA methylation of specific genes expressed in the brain, revealing physical, biochemical and molecular paths for the epidemiological concept of gene-environment interactions...
2017: Frontiers in Behavioral Neuroscience
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