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https://www.readbyqxmd.com/read/27933677/the-effect-of-slow-paced-breathing-on-stress-management-in-adolescents-with-intellectual-disability
#1
S Laborde, M S Allen, N Göhring, F Dosseville
BACKGROUND: Intellectual disabilities often create a state of chronic stress for both the person concerned and their significant others (family, caregivers). The development of stress management methods is therefore important for the reduction of stress in persons with intellectual disability. The aim of this experiment was to investigate the effect of slow-paced breathing on stress symptoms experienced by adolescents with intellectual disabilities during a cognitive task under time pressure...
December 9, 2016: Journal of Intellectual Disability Research: JIDR
https://www.readbyqxmd.com/read/27933467/osteosarcoma-overview
#2
REVIEW
Brock A Lindsey, Justin E Markel, Eugenie S Kleinerman
Osteosarcoma (OS) is the most common primary malignancy of bone and patients with metastatic disease or recurrences continue to have very poor outcomes. Unfortunately, little prognostic improvement has been generated from the last 20 years of research and a new perspective is warranted. OS is extremely heterogeneous in both its origins and manifestations. Although multiple associations have been made between the development of osteosarcoma and race, gender, age, various genomic alterations, and exposure situations among others, the etiology remains unclear and controversial...
December 8, 2016: Rheumatology and Therapy
https://www.readbyqxmd.com/read/27933251/robust-image-hashing-using-ring-partition-pgnmf-and-local-features
#3
Ram Kumar Karsh, R H Laskar, Bhanu Bhai Richhariya
BACKGROUND: Image authentication is one of the challenging research areas in the multimedia technology due to the availability of image editing tools. Image hash may be used for image authentication which should be invariant to perceptually similar image and sensitive to content changes. The challenging issue in image hashing is to design a system which simultaneously provides rotation robustness, desirable discrimination, sensitivity and localization of forged area with minimum hash length...
2016: SpringerPlus
https://www.readbyqxmd.com/read/27933246/a-quantitative-report-on-the-impact-of-chloride-on-the-kinetic-coefficients-of-auxin-induced-growth-a-numerical-contribution-to-the-acid-growth-hypothesis
#4
Mariusz Pietruszka, Aleksandra Haduch-Sendecka
This work presents the application of several our own novel methods of analysing the kinetics of plant growth, which create, among others, a common platform for the comparison of experimental results. A relatively simple formula is used to parameterize the wide range of data that has been obtained for Zea mays L. in the literature, though it can also be used for different species. A biophysical/biochemical interpretation of the parameters was obtained from a theoretical model that is based on a modified Lockhart equation...
2016: SpringerPlus
https://www.readbyqxmd.com/read/27933055/responses-of-methanogenic-and-methanotrophic-communities-to-elevated-atmospheric-co2-and-temperature-in-a-paddy-field
#5
Yuan Liu, Xiaoyu Liu, Kun Cheng, Lianqing Li, Xuhui Zhang, Jufeng Zheng, Jinwei Zheng, Genxing Pan
Although climate change is predicted to affect methane (CH4) emissions in paddy soil, the dynamics of methanogens and methanotrophs in paddy fields under climate change have not yet been fully investigated. To address this issue, a multifactor climate change experiment was conducted in a Chinese paddy field using the following experimental treatments: (1) enrichment of atmospheric CO2 concentrations (500 ppm, CE), (2) canopy air warming (2°C above the ambient, WA), (3) combined CO2 enrichment and warming (CW), and (4) ambient conditions (CK)...
2016: Frontiers in Microbiology
https://www.readbyqxmd.com/read/27932868/analysis-of-parallel-algorithms-on-smp-node-and-cluster-of-workstations-using-parallel-programming-models-with-new-tile-based-method-for-large-biological-datasets
#6
D D Shrimankar, S R Sathe
Sequence alignment is an important tool for describing the relationships between DNA sequences. Many sequence alignment algorithms exist, differing in efficiency, in their models of the sequences, and in the relationship between sequences. The focus of this study is to obtain an optimal alignment between two sequences of biological data, particularly DNA sequences. The algorithm is discussed with particular emphasis on time, speedup, and efficiency optimizations. Parallel programming presents a number of critical challenges to application developers...
2016: Bioinformatics and Biology Insights
https://www.readbyqxmd.com/read/27931886/neurobiological-after-effects-of-non-invasive-brain-stimulation
#7
REVIEW
G Cirillo, G Di Pino, F Capone, F Ranieri, L Florio, V Todisco, G Tedeschi, K Funke, V Di Lazzaro
BACKGROUND: In recent years, many studies have evaluated the effects of noninvasive brain stimulation (NIBS) techniques for the treatment of several neurological and psychiatric disorders. Positive results led to approval of NIBS for some of these conditions by the Food and Drug Administration in the USA. The therapeutic effects of NIBS have been related to bi-directional changes in cortical excitability with the direction of change depending on the choice of stimulation protocol. Although after-effects are mostly short lived, complex neurobiological mechanisms related to changes in synaptic excitability bear the potential to further induce therapy-relevant lasting changes...
November 17, 2016: Brain Stimulation
https://www.readbyqxmd.com/read/27931875/efficacy-of-antimicrobial-photodynamic-therapy-in-the-disinfection-of-acrylic-denture-surfaces-a-systematic-review
#8
REVIEW
Sergio Varela Kellesarian, Tariq Abduljabbar, Fahim Vohra, Hans Malmstrom, Michael Yunker, Tammy Varela Kellesarian, Georgios E Romanos, Fawad Javed
BACKGROUND: the aim of the present systematic review was to assess the efficacy of antimicrobial photodynamic therapy (aPDT) in the disinfection of acrylic denture surfaces. METHODS: in order to address the focused question: "Is aPDT more effective in decontaminating denture surfaces compared with traditional denture-disinfection techniques?" an electronic search without time or language restrictions was conducted up to November 2016 in indexed databases using different key words...
December 5, 2016: Photodiagnosis and Photodynamic Therapy
https://www.readbyqxmd.com/read/27931196/attentional-bias-modification-in-depression-through-gaze-contingencies-and-regulatory-control-using-a-new-eye-tracking-intervention-paradigm-study-protocol-for-a-placebo-controlled-trial
#9
Carmelo Vazquez, Ivan Blanco, Alvaro Sanchez, Richard J McNally
BACKGROUND: Attentional biases, namely difficulties both to disengage attention from negative information and to maintain it on positive information, play an important role in the onset and maintenance of the disorder. Recently, researchers have developed specific attentional bias modification (ABM) techniques aimed to modify these maladaptive attentional patterns. However, the application of current ABM procedures has yielded, so far, scarce results in depression due, in part, to some methodological shortcomings...
December 8, 2016: BMC Psychiatry
https://www.readbyqxmd.com/read/27930664/reliable-analysis-of-single-unit-recordings-from-the-human-brain-under-noisy-conditions-tracking-neurons-over-hours
#10
Johannes Niediek, Jan Boström, Christian E Elger, Florian Mormann
Recording extracellulary from neurons in the brains of animals in vivo is among the most established experimental techniques in neuroscience, and has recently become feasible in humans. Many interesting scientific questions can be addressed only when extracellular recordings last several hours, and when individual neurons are tracked throughout the entire recording. Such questions regard, for example, neuronal mechanisms of learning and memory consolidation, and the generation of epileptic seizures. Several difficulties have so far limited the use of extracellular multi-hour recordings in neuroscience: Datasets become huge, and data are necessarily noisy in clinical recording environments...
2016: PloS One
https://www.readbyqxmd.com/read/27929692/osteoporotic-animal-models-of-bone-healing-advantages-and-pitfalls
#11
Elena Calciolari, Nikolaos Donos, Nikos Mardas
The aim of this review was to summarize the advantages and pitfalls of the available osteoporotic animal models of bone healing. A thorough literature search was performed in MEDLINE via OVID and EMBASE to identify animal studies investigating the effect of experimental osteoporosis on bone healing and bone regeneration. The osteotomy model in the proximal tibia is the most popular osseous defect model to study the bone healing process in osteoporotic-like conditions, although other well-characterized models, such as the post-extraction model, might be taken into consideration by future studies...
December 8, 2016: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/27929455/neuropharmacological-manipulation-of-restrained-and-free-flying-honey-bees-apis-mellifera
#12
Eirik Søvik, Jenny A Plath, Jean-Marc Devaud, Andrew B Barron
Honey bees demonstrate astonishing learning abilities and advanced social behavior and communication. In addition, their brain is small, easy to visualize and to study. Therefore, bees have long been a favored model amongst neurobiologists and neuroethologists for studying the neural basis of social and natural behavior. It is important, however, that the experimental techniques used to study bees do not interfere with the behaviors being studied. Because of this, it has been necessary to develop a range of techniques for pharmacological manipulation of honey bees...
November 26, 2016: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/27928935/taking-the-stock-of-granule-cargo-platelet-releasate-proteomics
#13
Oliver Pagel, Elena Walter, Kerstin Jurk, René P Zahedi
Human platelets are key players in a multitude of physiological and pathological processes. Upon activation they release cargo from different types of granules as well as microparticles in an apparently well-regulated and orchestrated manner. The resulting specific platelet releasates create microenvironments of biologically active compounds and proteins during platelet aggregation and thrombus formation, allowing efficient delivery of growth factors and immune modulators to their sites of effect and enhancing the coagulative response in a positive feedback loop...
December 8, 2016: Platelets
https://www.readbyqxmd.com/read/27928551/drug-discrimination-and-the-analysis-of-private-events
#14
Brian D Kangas, David R Maguire
A defining feature of radical behaviorism is the explicit inclusion of private events as material phenomena within a science of behavior. Surprisingly, however, despite much theorizing, there is a notable paucity within behavior analysis of controlled experimentation and analysis of private events, especially in nonhuman animals. One technique that is amenable to the study of private events is drug discrimination. For over 40 years, drug discrimination procedures have been an incredibly effective tool providing a wealth of in vivo pharmacological information about drugs including receptor selectivity, potency, and efficacy...
November 2016: Behav Anal (Wash D C)
https://www.readbyqxmd.com/read/27927188/investigating-potentially-salvageable-penumbra-tissue-in-an-in-vivo-model-of-transient-ischemic-stroke-using-sodium-diffusion-and-perfusion-magnetic-resonance-imaging
#15
Friedrich Wetterling, Eva Chatzikonstantinou, Laurent Tritschler, Stephen Meairs, Marc Fatar, Lothar R Schad, Saema Ansar
BACKGROUND: Diffusion magnetic resonance imaging (MRI) is the current-state-of-the-art technique to clinically investigate acute (0-24 h) ischemic stroke tissue. However, reduced apparent diffusion coefficient (ADC)-considered a marker of tissue damage-was observed to reverse spontaneously during the subacute stroke phase (24-72 h) which means that low ADC cannot be used to reflect the damaged tissue after 24 h in experimental and clinical studies. One reason for the change in ADC is that ADC values drop with cytotoxic edema (acute phase) and rise when vasogenic edema begins (subacute phase)...
December 7, 2016: BMC Neuroscience
https://www.readbyqxmd.com/read/27926437/involvement-of-opioid-signaling-in-food-preference-and-motivation-studies-in-laboratory-animals
#16
I Morales, L Font, P J Currie, R Pastor
Motivation is a complex neurobiological process that initiates, directs, and maintains goal-oriented behavior. Although distinct components of motivated behavior are difficult to investigate, appetitive and consummatory phases of motivation are experimentally separable. Different neurotransmitter systems, particularly the mesolimbic dopaminergic system, have been associated with food motivation. Over the last two decades, however, research focusing on the role of opioid signaling has been particularly growing in this area...
2016: Progress in Brain Research
https://www.readbyqxmd.com/read/27925713/ramsey-interference-with-single-photons
#17
Stéphane Clemmen, Alessandro Farsi, Sven Ramelow, Alexander L Gaeta
Interferometry using discrete energy levels of nuclear, atomic, or molecular systems is the foundation for a wide range of physical phenomena and enables powerful techniques such as nuclear magnetic resonance, electron spin resonance, Ramsey-based spectroscopy, and laser or maser technology. It also plays a unique role in quantum information processing as qubits may be implemented as energy superposition states of simple quantum systems. Here, we demonstrate quantum interference involving energy states of single quanta of light...
November 25, 2016: Physical Review Letters
https://www.readbyqxmd.com/read/27925231/experimental-approach-to-visualize-flow-in-a-stacked-hollow-fiber-bundle-of-an-artificial-lung-with-particle-image-velocimetry
#18
Andreas Kaesler, Peter C Schlanstein, Felix Hesselmann, Martin Büsen, Michael Klaas, Dorothee Roggenkamp, Thomas Schmitz-Rode, Ulrich Steinseifer, Jutta Arens
Flow distribution is key in artificial lungs, as it directly influences gas exchange performance as well as clot forming and blood damaging potential. The current state of computational fluid dynamics (CFD) in artificial lungs can only give insight on a macroscopic level due to model simplification applied to the fiber bundle. Based on our recent work on wound fiber bundles, we applied particle image velocimetry (PIV) to the model of an artificial lung prototype intended for neonatal use to visualize flow distribution in a stacked fiber bundle configuration to (i) evaluate the feasibility of PIV for artificial lungs, (ii) validate CFD in the fiber bundle of artificial lungs, and (iii) give a suggestion how to incorporate microscopic aspects into mainly macroscopic CFD studies...
December 7, 2016: Artificial Organs
https://www.readbyqxmd.com/read/27924485/small-molecules-targeting-the-mirna-binding-domain-of-argonaute-2-from-computer-aided-molecular-design-to-rna-immunoprecipitation
#19
Teresa Bellissimo, Silvia Masciarelli, Elena Poser, Ilaria Genovese, Alberto Del Rio, Gianni Colotti, Francesco Fazi
The development of small-molecule-based target therapy design for human disease and cancer is object of growing attention. Recently, specific microRNA (miRNA) mimicking compounds able to bind the miRNA-binding domain of Argonaute 2 protein (AGO2) to inhibit miRNA loading and its functional activity were described. Computer-aided molecular design techniques and RNA immunoprecipitation represent suitable approaches to identify and experimentally determine if a compound is able to impair the loading of miRNAs on AGO2 protein...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/27924441/chronset-an-automated-tool-for-detecting-speech-onset
#20
Frédéric Roux, Blair C Armstrong, Manuel Carreiras
The analysis of speech onset times has a longstanding tradition in experimental psychology as a measure of how a stimulus influences a spoken response. Yet the lack of accurate automatic methods to measure such effects forces researchers to rely on time-intensive manual or semiautomatic techniques. Here we present Chronset, a fully automated tool that estimates speech onset on the basis of multiple acoustic features extracted via multitaper spectral analysis. Using statistical optimization techniques, we show that the present approach generalizes across different languages and speaker populations, and that it extracts speech onset latencies that agree closely with those from human observations...
December 6, 2016: Behavior Research Methods
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