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https://www.readbyqxmd.com/read/28644033/direct-indirect-nature-of-the-bandgap-in-lead-free-perovskite-nanocrystals
#1
Yuhai Zhang, Jun Yin, Manas R Parida, Ghada H Ahmed, Jun Pan, Osman M Bakr, Jean-Luc Bredas, Omar F Mohammed
With record efficiencies achieved in lead halide perovskite-based photovoltaics, urgency has shifted towards finding alternative materials that are stable and less-toxic. Bismuth-based perovskite materials are currently one of the most promising candidates amongst those alternatives. However, the band structures of these materials, including the nature of the bandgaps, remain elusive due to extremely low photoluminescence quantum yield (PLQY) and scattering issues in their thin-film or bulk form. Here, we overcome those limitations and reveal the specific nature of the material's electronic transitions by realizing monodisperse colloidal nanocrystals (NCs) of hexagonal-phase Cs3Bi2X9 perovskites, which afford well-resolved PL features...
June 23, 2017: Journal of Physical Chemistry Letters
https://www.readbyqxmd.com/read/28642223/performing-high-level-sport-is-strongly-associated-with-urinary-incontinence-in-elite-athletes-a-comparative-study-of-372-elite-female-athletes-and-372-controls
#2
Alice Carvalhais, Jorge Renato Natal, Kari Bø
OBJECTIVE: To evaluate the prevalence of urinary incontinence (UI) in female elite athletes compared with controls and to investigate potential risk factors for UI among elite athletes. METHODS: This cross-sectional study included 372 elite athletes (athletes group, AG) and 372 age-matched controls (control group, CG). The median age was low (19 years) and the vast majority were nulliparous. Potential risk factors, including clinical, demographic and sports practice characteristics, were collected by using a questionnaire...
June 22, 2017: British Journal of Sports Medicine
https://www.readbyqxmd.com/read/28640871/nomogram-to-predict-rectal-toxicity-following-prostate-cancer-radiotherapy
#3
Jean-Bernard Delobel, Khemara Gnep, Juan David Ospina, Véronique Beckendorf, Ciprian Chira, Jian Zhu, Alberto Bossi, Taha Messai, Oscar Acosta, Joël Castelli, Renaud de Crevoisier
BACKGROUND: To identify predictors of acute and late rectal toxicity following prostate cancer radiotherapy (RT), while integrating the potential impact of RT technique, dose escalation, and moderate hypofractionation, thus enabling us to generate a nomogram for individual prediction. METHODS: In total, 972 patients underwent RT for localized prostate cancer, to a total dose of 70 Gy or 80 Gy, using two different fractionations (2 Gy or 2.5 Gy/day), by means of several RT techniques (3D conformal RT [3DCRT], intensity-modulated RT [IMRT], or image-guided RT [IGRT])...
2017: PloS One
https://www.readbyqxmd.com/read/28637479/pediatric-emental-healthcare-technologies-a-systematic-review-of-implementation-foci-in-research-studies-and-government-and-organizational-documents
#4
REVIEW
Nicole D Gehring, Patrick McGrath, Lori Wozney, Amir Soleimani, Kathryn Bennett, Lisa Hartling, Anna Huguet, Michele P Dyson, Amanda S Newton
BACKGROUND: Researchers, healthcare planners, and policymakers convey a sense of urgency in using eMental healthcare technologies to improve pediatric mental healthcare availability and access. Yet, different stakeholders may focus on different aspects of implementation. We conducted a systematic review to identify implementation foci in research studies and government/organizational documents for eMental healthcare technologies for pediatric mental healthcare. METHODS: A search of eleven electronic databases and grey literature was conducted...
June 21, 2017: Implementation Science: IS
https://www.readbyqxmd.com/read/28636311/insights-into-integrated-lead-generation-and-target-identification-in-malaria-and-tuberculosis-drug-discovery
#5
John Okombo, Kelly Chibale
New, safe and effective drugs are urgently needed to treat and control malaria and tuberculosis, which affect millions of people annually. However, financial return on investment in the poor settings where these diseases are mostly prevalent is very minimal to support market-driven drug discovery and development. Moreover, the imminent loss of therapeutic lifespan of existing therapies due to evolution and spread of drug resistance further compounds the urgency to identify novel effective drugs. However, the advent of new public-private partnerships focused on tropical diseases and the recent release of large data sets by pharmaceutical companies on antimalarial and antituberculosis compounds derived from phenotypic whole cell high throughput screening have spurred renewed interest and opened new frontiers in malaria and tuberculosis drug discovery...
June 21, 2017: Accounts of Chemical Research
https://www.readbyqxmd.com/read/28634455/fertilizing-a-patient-engagement-ecosystem-to-innovate-healthcare-toward-the-first-italian-consensus-conference-on-patient-engagement
#6
Guendalina Graffigna, Serena Barello, Giuseppe Riva, Mariarosaria Savarese, Julia Menichetti, Gianluca Castelnuovo, Massimo Corbo, Alessandra Tzannis, Antonio Aglione, Donato Bettega, Anna Bertoni, Sarah Bigi, Daniela Bruttomesso, Claudia Carzaniga, Laura Del Campo, Silvia Donato, Silvia Gilardi, Chiara Guglielmetti, Michele Gulizia, Mara Lastretti, Valeria Mastrilli, Antonino Mazzone, Giovanni Muttillo, Silvia Ostuzzi, Gianluca Perseghin, Natalia Piana, Giuliana Pitacco, Gianluca Polvani, Massimo Pozzi, Livio Provenzi, Giulia Quaglini, Mariagrazia Rossi, Paola Varese, Natalia Visalli, Elena Vegni, Walter Ricciardi, A Claudio Bosio
Currently we observe a gap between theory and practices of patient engagement. If both scholars and health practitioners do agree on the urgency to realize patient engagement, no shared guidelines exist so far to orient clinical practice. Despite a supportive policy context, progress to achieve greater patient engagement is patchy and slow and often concentrated at the level of policy regulation without dialoguing with practitioners from the clinical field as well as patients and families. Though individual clinicians, care teams and health organizations may be interested and deeply committed to engage patients and family members in the medical course, they may lack clarity about how to achieve this goal...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28632532/postpartum-tubal-sterilization-making-the-case-for-urgency
#7
Michael G Richardson, Sarah J Hall, Lisa C Zuckerwise
The parturient who requests postpartum sterilization has given consideration to and has made decisions regarding this aspect of her medical care long before her delivery. She arrives at parturition expecting the postpartum procedure to be performed as intended. The American Congress of Obstetricians and Gynecologists has reaffirmed its opinion that postpartum sterilization is an urgent procedure, owing to the safety and superior effectiveness of tubal sterilization via minilaparotomy in the immediate postpartum period, and the adverse consequences for mothers, babies, and society when the procedure is not actualized as desired and intended...
June 17, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28631830/overactive-bladder-symptoms-after-midurethral-sling-surgery-in-women-risk-factors-and-management
#8
Tom Marcelissen, Philip Van Kerrebroeck
INTRODUCTION: Overactive bladder syndrome (OAB) including urgency and urgency urinary incontinence (UUI) occurs frequently after stress urinary incontinence (SUI) surgery. It is important to identify the risk factors for the occurrence of OAB symptoms in order to adequately inform the patient before surgery. Furthermore, when facing OAB after sling surgery it is crucial to know how to manage these symptoms. METHODS: We conducted a literature review in order to assess the risk factors and management of OAB symptoms after SUI surgery...
June 20, 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/28631489/an-update-on-the-recognition-and-treatment-of-autonomic-symptoms-in-parkinson-s-disease
#9
Wolfgang H Jost
Parkinson's disease (PD) is characterized by motor, autonomic, and neuropsychiatric symptoms. These occur in varying degrees in all stages of the disease. Among the autonomic disorders, cardiovascular, urogenital, gastrointestinal and thermoregulatory disorders are the most relevant. Within cardiovascular disorders drop of blood pressure after orthostasis and non-dipper behavior are very important; but also the influence of cardiovascular medication. Urgency, nocturia, and incontinence are of particular note within the urological problems...
June 20, 2017: Expert Review of Neurotherapeutics
https://www.readbyqxmd.com/read/28631089/targeted-temperature-management-in-the-icu-guidelines-from-a-french-expert-panel
#10
REVIEW
Alain Cariou, Jean-François Payen, Karim Asehnoune, Gerard Audibert, Astrid Botte, Olivier Brissaud, Guillaume Debaty, Sandrine Deltour, Nicolas Deye, Nicolas Engrand, Gilles Francony, Stéphane Legriel, Bruno Levy, Philippe Meyer, Jean-Christophe Orban, Sylvain Renolleau, Bernard Vigue, Laure De Saint Blanquat, Cyrille Mathien, Lionel Velly
Over the recent period, the use of induced hypothermia has gained an increasing interest for critically ill patients, in particular in brain-injured patients. The term "targeted temperature management" (TTM) has now emerged as the most appropriate when referring to interventions used to reach and maintain a specific level temperature for each individual. TTM may be used to prevent fever, to maintain normothermia, or to lower core temperature. This treatment is widely used in intensive care units, mostly as a primary neuroprotective method...
December 2017: Annals of Intensive Care
https://www.readbyqxmd.com/read/28627109/high-power-magnetotherapy-a-new-weapon-in-urinary-incontinence
#11
Maria Vadalà, Beniamino Palmieri, Andrea Malagoli, Carmen Laurino
OBJECTIVE: Urinary incontinence (UI) is one of the most common urinary system diseases that mostly affects women but also men. We evaluated the therapeutic efficacy of functional magnetic stimulation (FMS) as potential UI treatment with improvements in the pelvic floor musculature, urodynamic tests and quality of life. METHODS: A total of 20 UI patients (10 females and 10 men, mean age 64, 14 years), including 10 with stress UI, four with urgency UI and six with mixed UI, were treated with FMS (20 min/session) twice a week for 3 weeks...
June 18, 2017: Lower Urinary Tract Symptoms
https://www.readbyqxmd.com/read/28625956/comparison-of-anti-bph-capsule-herbal-and-terazosin-hcl-in-the-treatment-of-benign-prostate-hyperplasia
#12
Hafiz Mohammad Rashid Nadeem, Ejaz Mohiuddin, Shahab UdDin, Muhammad Daniyal, Khan Usmanghani
Benign prostatic hyperplasia (BPH) is a disease of senile age, usually occurring> 60 years of age. BPH is a disease that involves cell proliferation of the prostate. Pathological hyperplasia affects the elements of the glandular and connective tissue of the prostate. This study is designed to scrutinize the efficacy and tolerability of herbal drug Anti BPH capsule for the management of benign prostate hyperplasia (BPH), in this study we select the 100 patients in which 50 received the Anti BPH capsule and 50 received the Terazosin HCl...
January 2017: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28623720/next-generation-precision-antimicrobials-towards-personalized-treatment-of-infectious-diseases
#13
REVIEW
Cesar de la Fuente-Nunez, Marcelo Dt Torres, Francisco Jm Mojica, Timothy K Lu
Antibiotics started to be used almost 90 years ago to eradicate life-threatening infections. The urgency of the problem required rapid, broad-spectrum elimination of infectious agents. Since their initial discovery, these antimicrobials have saved millions of lives. However, they are not exempt from side effects, which include the indiscriminate disruption of the beneficial microbiota. Recent technological advances have enabled the development of antimicrobials that can selectively target a gene, a cellular process, or a microbe of choice...
June 14, 2017: Current Opinion in Microbiology
https://www.readbyqxmd.com/read/28622875/does-the-severity-of-overactive-bladder-symptoms-correlate-with-risk-for-female-sexual-dysfunction
#14
Cássia Raquel Teatin Juliato, Iane Glauce Ribeiro Melotti, Luiz Carlos Santos Junior, Luiz Gustavo Oliveira Britto, Cássio Luiz Zanettini Riccetto
BACKGROUND: Several studies have associated overactive bladder (OAB) with female sexual dysfunction (FSD); however, there are no reports using a quantitative approach to measure OAB severity and to relate OAB to the risk of FSD. AIM: To evaluate women with OAB and to correlate the severity of their urinary symptoms with their sexual function. METHODS: This cross-sectional study included 267 women older than 18 years with untreated OAB. All subjects completed the International Consultation on Incontinence Questionnaire Overactive Bladder (ICIQ-OAB) and the Female Sexual Function Index (FSFI)...
June 13, 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/28618249/an-integrative-study-of-motivation-and-goal-regulation-processes-in-subclinical-anxiety-depression-and-hypomania
#15
Joanne M Dickson, Sheri Johnson, Christopher D Huntley, Andrew Peckham, Peter J Taylor
Research has implicated motivation and goal regulation in susceptibility to mood disorders. We studied for the first time key facets of motivation and goal regulation concurrently in relation to affective symptoms. The cross-national sample comprised 510 university students from the United States (n = 279) and United Kingdom (n = 231). Participants completed self-report measures of motivation, conditional goal setting, urgency, depression, anxiety, and mania risk. Structural Equation Modeling results found that behavioral activation system scores correlated negatively with depression and positively with mania risk, but were unrelated to anxiety...
June 3, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28618234/successful-treatment-of-acute-radiation-proctitis-with-aloe-vera-a-preliminary-randomized-controlled-clinical-trial
#16
Adeleh Sahebnasagh, Arash Ghasemi, Jafar Akbari, Abbas Alipour, Hossein Lashkardoost, Shahram Ala, Ebrahim Salehifar
BACKGROUND: Acute radiation proctitis (ARP) is a common side-effect that affects up to 50% of patients receiving radiotherapy. The aim of this study was to evaluate the role of a topical preparation of Aloe vera in the treatment of ARP induced by radiotherapy of pelvic area. SUBJECTS AND INTERVENTIONS: In this double-blind placebo-controlled trial, 20 consecutive patients with ARP after external-beam radiation therapy (46-72 Gy) of pelvic malignancies were randomized to receive either Aloe vera 3% or placebo ointment, 1 g twice daily for 4 weeks...
June 15, 2017: Journal of Alternative and Complementary Medicine: Research on Paradigm, Practice, and Policy
https://www.readbyqxmd.com/read/28617730/eye-symptom-questionnaire-to-evaluate-anterior-eye-health
#17
Maria A Woodward, Nita G Valikodath, Paula Anne Newman-Casey, Leslie M Niziol, David C Musch, Paul P Lee
OBJECTIVES: Ophthalmologists assess eye complaints with a careful history and eye examination; however, other types of physicians have limited tools to evaluate anterior segment (AS) eye diseases. We identified the eye symptom questions that providers should ask to help determine the presence and urgency of AS eye diseases. METHODS: Persons with and without AS disease completed a self-report eye symptom questionnaire (ESQ) based on the National Institutes of Health Toolbox symptom items in an academic center's corneal and comprehensive eye clinics...
June 14, 2017: Eye & Contact Lens
https://www.readbyqxmd.com/read/28616109/the-management-of-mixed-urinary-incontinence-in-women
#18
REVIEW
Blayne Welk, Richard J Baverstock
Mixed urinary incontinence is a common diagnosis among women with urinary leakage and is often present in women who are unable to characterize their incontinence. Research and optimized clinical treatment of these patients is limited by the challenges in objectively defining and stratifying this population. The evaluation of these patients should follow the same general principles as any assessment of any women with incontinence; however, it is essential to define whether urge or stress incontinence is the predominant symptom...
June 2017: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/28615929/impact-of-serum-derived-bovine-immunoglobulin-protein-isolate-therapy-on-irritable-bowel-syndrome-and-inflammatory-bowel-disease-a-survey-of-patient-perspective
#19
Audrey L Shaw, Adam Tomanelli, Timothy P Bradshaw, Bryon W Petschow, Bruce P Burnett
BACKGROUND: Patients with irritable bowel syndrome (IBS) or inflammatory bowel disease (IBD) commonly experience diarrhea, abdominal pain, bloating, and urgency. These symptoms significantly compromise the patient's quality of life (QoL) by limiting participation in normal daily activities and adversely affect work productivity and performance. PURPOSE: The aim of this study was to understand from the patient's perspective how oral serum-derived bovine immunoglobulin/protein isolate (SBI) impacts bowel habits, management of condition, and basic QoL...
2017: Patient Preference and Adherence
https://www.readbyqxmd.com/read/28614952/phirst-trial-pharmacist-consults-prioritization-of-hiv-patients-with-a-referral-screening-tool
#20
Catherine Awad, Arnaud Canneva, Charles-Olivier Chiasson, Annie Galarneau, Mireille E Schnitzer, Nancy L Sheehan, Alison Yj Wong
The role of pharmacists in HIV outpatient clinics has greatly increased in the past decades. Given the limited resources of the health system, the prioritization of pharmacist consults is now a main concern. This study aimed to create a scoring system allowing for standardized prioritization of pharmacist consults for patients living with HIV. Data was retrospectively collected from 200 HIV patients attending the Chronic Viral Illness Service at the McGill University Health Center. An expert panel consisting of four pharmacists working in the field of HIV prioritized each patient individually, after which a consensus was established and was considered as the gold standard...
June 14, 2017: AIDS Care
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