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Deglutition physiology

Rob J C G Verdonschot, Laura W J Baijens, Sophie Vanbelle, Michelle Florie, Remco Dijkman, Irene P M Leeters, Bernd Kremer, Carsten Leue
Medically unexplained oropharyngeal dysphagia (MUNOD) is a rare condition. It presents without demonstrable abnormalities in the anatomy of the upper aero-digestive tract and/or swallowing physiology. This study investigates whether MUNOD is related to affective or other psychiatric conditions. The study included patients with dysphagic complaints who had no detectible structural or physiological abnormalities upon swallowing examination. Patients with any underlying disease or disorder that could explain the oropharyngeal dysphagia were excluded...
June 5, 2018: Dysphagia
Yipu Xu, Baoxing Pang, Liang Hu, Xiaoyu Feng, Lei Hu, Jingsong Wang, Chunmei Zhang, Songlin Wang
Xerostomia, a major oral symptom of menopause, is a subjective feeling of dry mouth associated with oral pain and difficulties in deglutition and speech, which significantly reduces patient's quality of life. Dietary nitrate, which can be converted to nitric oxide, has multiple physiological functions in the body, including antioxidant activity and vasodilatation; however, its protective effect against xerostomia remains poorly understood. The present study aimed to evaluate the effects of dietary nitrate on estrogen deficiency-induced xerostomia...
February 26, 2018: Biochemical and Biophysical Research Communications
Sarah P Rosen, Suzan M Abdelhalim, Corinne A Jones, Timothy M McCulloch
The effect of body position and gravitational pull on the complex pressure-driven process of pharyngeal swallowing remains unknown. Using high-resolution manometry (HRM), this study aims to identify positional adaptations of pharyngeal physiology by evaluating swallowing pressure patterns in a series of inverted body positions. Ten healthy adults each underwent swallowing tasks with pharyngeal HRM at six body positions using an inversion table (0°[upright], 45°, 90°[supine], 110°, 135°, and 180°[fully inverted])...
December 7, 2017: Dysphagia
Maureen A Lefton-Greif, Katlyn Elizabeth McGrattan, Kathryn A Carson, Jeanne M Pinto, Jennifer M Wright, Bonnie Martin-Harris
The incidence of feeding/swallowing impairments (deglutition disorders) in young children is rising and poses serious acute and long-term health consequences. Accurate detection and prompt intervention can lessen the impact of dysphagia-induced sequelae. Videofluoroscopic Swallow Studies (VFSSs) are used to make critical decisions for medically fragile children despite procedural variability and the lack of agreed upon measures for interpreting and reporting results. This investigation represents the first steps in the development of a novel tool for the quantification of oropharyngeal swallow physiology from full-length VFSS examinations in bottle-fed children...
February 2018: Dysphagia
G Balasubramanian, T Sharma, M Kern, L Mei, P Sanvanson, R Shaker
BACKGROUND: Recent technological advances incorporated in high resolution manometry have justifiably heightened interest in manometric evaluation of the pharynx. Despite this interest, from both physiologic and clinical perspective there remain a number of unanswered questions regarding the magnitude of variability of pharyngeal pressure phenomena. Therefore, the aim of the present study was to characterize in healthy individuals the inter-subject and recording-site specific variability of pharyngeal peristaltic pressure phenomena...
November 2017: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
Stephanie A Watts, Lauren Tabor, Emily K Plowman
PURPOSE: The clinical swallowing evaluation (CSE) represents a critical component of a comprehensive assessment of deglutition. Although universally utilized across clinical settings, the CSE demonstrates limitations in its ability to accurately identify all individuals with dysphagia. There exists a need to improve assessment and screening techniques to improve health outcomes, treatment recommendations and ultimately mortality in individuals at risk for dysphagia. The following narrative review provides a summary of currently used validated CSE's and examines the potential role of cough testing and screening in the CSE...
December 2016: Current Physical Medicine and Rehabilitation Reports
Elliot Abemayor
INTRODUCTION: Sir Charles Bell is renowned and revered as an outstanding surgeon, anatomist, clinician and teacher and his many contributions to various medical fields have been amply described. What are less well-known are his contributions to the field of laryngology. METHODS: Selected clinical and physiological publications by Bell were examined that addressed issues related specifically to the airway or pharynx. These included both case reports and case series...
April 21, 2017: American Journal of Otolaryngology
Christopher Cabib, Omar Ortega, Hatice Kumru, Ernest Palomeras, Natalia Vilardell, Daniel Alvarez-Berdugo, Desirée Muriana, Laia Rofes, Rosa Terré, Fermín Mearin, Pere Clavé
Oropharyngeal dysphagia (OD) is very prevalent among poststroke patients, causing severe complications but lacking specific neurorehabilitation treatment. This review covers advances in the pathophysiology, diagnosis, and physiologically based neurorehabilitation strategies for poststroke OD. The pathophysiology of oropharyngeal biomechanics can be assessed by videofluoroscopy, as delayed laryngeal vestibule closure is closely associated with aspiration. Stroke may affect afferent or efferent neuronal circuits participating in deglutition...
September 2016: Annals of the New York Academy of Sciences
Sabri T Shuker
With the progress of multidisciplinary vascular anomaly treatment, the use of radiotherapy, cryotherapy, laser therapy and medical treatments, the corticosteroid, sclerotherapy, and many more, the role of surgery has been refined. Surgical treatment has historically been the mainstay of treatment and will maintain.A miniature tourniquet technique applied to the tongue was successfully utilized in reducing bleeding to a minimum during surgical resection of a massive cavernous hemangioma involving the tongue and lower lip without any postoperative complications...
July 2016: Journal of Craniofacial Surgery
Brittany N Krekeler, Nadine P Connor
OBJECTIVES/HYPOTHESIS: Aging results in progressive changes in deglutitive functions, which may be due in part to alterations in muscle morphology and physiology. Mastication is a critical component of bolus formation and swallowing, but aging effects on masticatory function have not been well studied. STUDY DESIGN: The purpose of this study was to 1) quantify the effects of aging on mastication, and 2) determine the effects of tongue exercise on mastication in young adult and old rats...
January 2017: Laryngoscope
Hongmei Jiao, Ling Mei, Tarun Sharma, Mark Kern, Patrick Sanvanson, Reza Shaker
Oropharyngeal dysphagia due to upper esophageal sphincter (UES) dysfunction is commonly encountered in the clinical setting. Selective experimental perturbation of various components of the deglutitive apparatus can provide an opportunity to improve our understanding of the swallowing physiology and pathophysiology. The aim is to characterize the pharyngeal and UES deglutitive pressure phenomena in an experimentally induced restriction of UES opening in humans. We studied 14 volunteers without any dysphagic symptoms (7 men, 66 ± 11 yr) but with various supraesophageal reflux symptoms...
July 1, 2016: American Journal of Physiology. Gastrointestinal and Liver Physiology
Karsten Ehrt, Hans-Georg Fischer, Rüdiger Dahl, Christoph Punke, Attila Ovari, Hans Wilhelm Pau
OBJECTIVE: To explore the origin of "physiological" ear clicks during deglutition or other pharyngeal movements, which, in contrast to disturbing frequent clicks under pathologic conditions, mostly remain unnoticed by the patient. STUDY DESIGN: Clinical experimental study at a tertiary referral center. METHODS: Ear clicks were recorded by a microphone sealing the external ear canal parallel to endoscopic or manometric evaluations of the Eustachian tube function...
April 2016: Otology & Neurotology
Robert B Gassert, William G Pearson
PURPOSE: Tongue base retraction during swallowing is critical to bolus propulsion in normal physiological swallowing. A better understanding of the hyoglossus and styloglossus, muscles thought to be key to tongue base retraction, will improve the quality of physical rehabilitation in dysphagic patients in addition to preventing iatrogenic damage to structures critical to deglutition. This study utilized muscle functional MRI in healthy adult human subjects in order to determine if the hyoglossus and styloglossus are active during swallowing...
February 2016: Magnetic Resonance Imaging
C-M Wang, W-Y Shieh, J-Y Chen, Y-R Wu
BACKGROUND: Oropharyngeal dysphagia is common after a stroke. Understanding the physiology of swallowing and its coordination with respiration in stroke recovery is crucially important. METHODS: A non-invasive swallowing assessment method was used to detect oropharyngeal swallowing and respiration coordination simultaneously during the swallowing process. This system detected movement of the larynx, submental muscle activity, and nasal airflow. Six different sizes of water boluses (maximum of 20 mL) were swallowed and assessed for each subject...
October 2015: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
Josef Finsterer, Wolfgang Grisold
Lesions of the lower cranial nerves (LCN) are due to numerous causes, which need to be differentiated to optimize management and outcome. This review aims at summarizing and discussing diseases affecting LCN. Review of publications dealing with disorders of the LCN in humans. Affection of multiple LCN is much more frequent than the affection of a single LCN. LCN may be affected solely or together with more proximal cranial nerves, with central nervous system disease, or with nonneurological disorders. LCN lesions have to be suspected if there are typical symptoms or signs attributable to a LCN...
July 2015: Journal of Neurosciences in Rural Practice
E Kamarunas, G H McCullough, M Mennemeier, T Munn
Bolus volume has been widely studied, and research has demonstrated a variety of physiological impacts on swallowing and swallowing disorders. Oral perception of bolus volume has not, to our knowledge, been investigated in association with normal ageing processes. Research suggests many sensory changes with age, some within the oral cavity, and changes in swallowing function with age have been defined. The role of perception in oropharyngeal deglutition with age requires further investigation. The purpose of this study was to establish the psychophysical relationship between liquid volume and oral perception and examine changes with age...
September 2015: Journal of Oral Rehabilitation
H K Su, A Khorsandi, J Silberzweig, A J Kobren, M L Urken, M R Amin, R C Branski, C L Lazarus
Cross-sectional imaging has long been employed to examine swallowing in both the sagittal and axial planes. However, data regarding temporal swallow measures in the upright and supine positions are sparse, and none have employed the MBS impairment profile (MBSImP). We report temporal swallow measures, physiologic variables, and swallow safety of upright and supine swallowing in healthy subjects using videofluoroscopy (VFS). Twenty healthy subjects ages 21-40 underwent VFS study upright and supine. Subjects were viewed in the sagittal plane and swallowed 5 mL liquid and pudding barium...
August 2015: Dysphagia
P Muhle, R Wirth, J Glahn, R Dziewas
The term presbyphagia refers to all changes of swallowing physiology that are manifested with increasing age. Alterations in the pattern of deglutition that are part of healthy aging are called primary presbyphagia. Primary presbyphagia is not an illness in itself but contributes to a more pervasive naturally diminished functional reserve, making older adults more susceptible to dysphagia. If disorders in swallowing occur in the elderly as a comorbidity of a specific disease, for example stroke or neurodegenerative disorders, this is called secondary presbyphagia...
April 2015: Der Nervenarzt
U Imtiaz, K Yamamura, W Kong, S Sessa, Z Lin, L Bartolomeo, H Ishii, M Zecca, Y Yamada, A Takanishi
Different types of sensors are being used to study deglutition and mastication. These often suffer from problems related to portability, cost, reliability, comfort etc. that make it difficult to use for long term studies. An inertial measurement based sensor seems a good fit in this application; however its use has not been explored much for the specific application of deglutition research. In this paper, we present a system comprised of an IMU and EMG sensor that are integrated together as a single system...
2014: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Jiesheng Qin, Huige Wang, Xinqiang Lin, Jiatao Chen, Xiong Shen, Bin Lin, Qinghai Lin, Jiefeng Wang, Shaoxiong Lin
OBJECTIVE: To investigate the feasibility and clinical characteristics of small partial laryngectomy without tracheotomy for T1-2 stage glottic carcinoma. METHOD: Forty-five patients with laryngeal squamaous cell carcinoma in T1-2 stage received small partial laryngectomy without tracheotomy. RESULT: All patients were primarily healed and were hospitalized for an average of 11.5 days post-operatively. In all patients, the function of respiration and the reflection of cough were normal, and laryngeal obstruction did not happen...
August 2014: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
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