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https://www.readbyqxmd.com/read/28699157/determination-of-cyclic-volatile-methylsiloxanes-in-personal-care-products-by-gas-chromatography
#1
Herbert M Brothers, Thomas Boehmer, Roy A Campbell, Steven Dorn, Joel J Kerbleski, Sarah Lewis, Christian Mund, Donald Pero, Kenji Saito, Michael Wieser, Wolfgang Zoller
OBJECTIVE: Organosiloxanes are prevalent in personal care products (PCPs) due to the desired properties they impart in the usage and application of such products. However, the European Chemical Agency (ECHA) has recently published restriction proposals on the amount of two cyclic siloxanes, octamethylcyclotetrasiloxane (D4) and decamethylcyclotetrasiloxane (D5) allowed in wash off products such as shampoos and conditioners which are discharged down the drain during consumer use. This legislation will require that reliable analytical methods are available for manufacturers and government agencies to use in documenting compliance with the restrictions...
July 12, 2017: International Journal of Cosmetic Science
https://www.readbyqxmd.com/read/28669379/the-prevalence-of-gestational-diabetes
#2
Hanne Melchior, Diana Kurch-Bek, Monika Mund
BACKGROUND: Gestational diabetes mellitus (GDM) is defined as a glucose tolerance disorder that arises during pregnancy. Estimates of its prevalence vary widely because of varying threshold values. Screening of all pregnant women with a two-step test has been available in Germany since 2012. This study is the first population-based, nationwide analysis of the screening coverage and the resulting one-year prevalence. METHODS: Billing data from the outpatient sector were analyzed for all persons covered by statutory health insurance in the two-year period 2014-2015...
July 16, 2017: Deutsches Ärzteblatt International
https://www.readbyqxmd.com/read/28667641/optimization-of-pectinase-assisted-and-tri-solvent-mediated-extraction-and-recovery-of-lycopene-from-waste-tomato-peels
#3
Pravin J Munde, Abhijeet B Muley, Mayur R Ladole, Amesh V Pawar, Mohammed I Talib, Vishal R Parate
In the present work, optimization of pectinase-assisted and tri-solvent-mediated extraction of lycopene from waste tomato peels was carried out. The optimized parameters for enzymatic pre-treatment were 2% pectinase concentration, pH 5.5, 4-h incubation, 45 °C and 150 rpm. Maximum recovery of lycopene from tomato peels using optimized tri-solvent extraction was achieved at 45 °C, 120-min incubation and 200 rpm. The extracted lycopene was confirmed through functional and characteristic peaks in UV-Vis and FTIR spectra and with retention time in HPLC...
July 2017: 3 Biotech
https://www.readbyqxmd.com/read/28623337/impact-of-module-x2-and-carbohydrate-binding-module-3-on-the-catalytic-activity-of-associated-glycoside-hydrolases-towards-plant-biomass
#4
Nandita Pasari, Nidhi Adlakha, Mayank Gupta, Zeenat Bashir, Girish H Rajacharya, Garima Verma, Manoj Munde, Rakesh Bhatnagar, Syed Shams Yazdani
Cellulolytic enzymes capable of hydrolyzing plant biomass are secreted by microbial cells specifically in response to the carbon substrate present in the environment. These enzymes consist of a catalytic domain, generally appended to one or more non-catalytic Carbohydrate Binding Module (CBM), which enhances their activity towards recalcitrant biomass. In the present study, the genome of a cellulolytic microbe Paenibacillus polymyxa A18 was annotated for the presence of CBMs and analyzed their expression in response to the plant biomass and model polysaccharides Avicel, CMC and xylan using quantitative PCR...
June 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28611251/erratum-for-mund-et-al-the-fitness-of-pseudomonas-aeruginosa-quorum-sensing-signal-cheats-is-influenced-by-the-diffusivity-of-the-environment
#5
Anne Mund, Stephen P Diggle, Freya Harrison
No abstract text is available yet for this article.
June 13, 2017: MBio
https://www.readbyqxmd.com/read/28589449/surprising-twist-in-the-plot-sister-mary-joseph-s-nodule-of-pancreatic-cancer-mimicking-wound-infection-after-umbilical-hernia-repair
#6
Andreas M Luu, K Meurer, T Herzog, J Munding, W Uhl, C Braumann
No abstract text is available yet for this article.
June 6, 2017: Journal of Gastrointestinal Cancer
https://www.readbyqxmd.com/read/28504974/diffusion-and-aggregation-of-oxygen-vacancies-in-amorphous-silica
#7
Manveer S Munde, David Z Gao, Alexander L Shluger
Using density functional theory (DFT) calculations, we investigated oxygen vacancy diffusion and aggregation in relation to dielectric breakdown in amorphous silicon dioxide (a-SiO2). Our calculations indicate the existence of favourable sites for the formation of vacancy dimers and trimers in the amorphous network with maximum binding energies of approximately 0.13 eV and 0.18 eV, respectively. However, an average energy barrier height for neutral vacancy diffusion is found to be about 4.6 eV, rendering this process unfeasible...
June 21, 2017: Journal of Physics. Condensed Matter: An Institute of Physics Journal
https://www.readbyqxmd.com/read/28473063/weight-loss-achieved-using-an-energy-restriction-diet-with-normal-or-higher-dietary-protein-decreased-the-number-of-cd14-cd16-proinflammatory-monocytes-and-plasma-lipids-and-lipoproteins-in-middle-aged-overweight-and-obese-adults
#8
Jung Eun Kim, Ge Lin, Jing Zhou, Julie A Mund, Jamie Case, Wayne W Campbell
Monocytes are involved in immune responses, and specific monocyte subpopulations (MS) that express intermediate to high levels of CD16 are associated with obesity and cardiovascular events. Consuming high protein (HP) when dieting improves body composition and cardiometabolic health outcomes, but whether HP affects MS during weight loss remains unknown. We assessed the effect of HP on energy restriction (ER)-induced changes in MS in overweight and obese adults. The relations between MS and plasma lipids and lipoproteins were also examined...
April 2017: Nutrition Research
https://www.readbyqxmd.com/read/28465424/the-fitness-of-pseudomonas-aeruginosa-quorum-sensing-signal-cheats-is-influenced-by-the-diffusivity-of-the-environment
#9
Anne Mund, Stephen P Diggle, Freya Harrison
Experiments examining the social dynamics of bacterial quorum sensing (QS) have focused on mutants which do not respond to signals and the role of QS-regulated exoproducts as public goods. The potential for QS signal molecules to themselves be social public goods has received much less attention. Here, we analyze how signal-deficient (lasI) mutants of the opportunistic pathogen Pseudomonas aeruginosa interact with wild-type cells in an environment where QS is required for growth. We show that when growth requires a "private" intracellular metabolic mechanism activated by the presence of QS signal, lasI mutants act as social cheats and outcompete signal-producing wild-type bacteria in mixed cultures, because they can exploit the signals produced by wild-type cells...
May 2, 2017: MBio
https://www.readbyqxmd.com/read/28427365/association-between-fc%C3%AE-receptor-iia-iiia-and-iiib-genetic-polymorphisms-and-susceptibility-to-severe-malaria-anemia-in-children-in-western-kenya
#10
Elly O Munde, Winnie A Okeyo, Evans Raballah, Samuel B Anyona, Tom Were, John M Ong'echa, Douglas J Perkins, Collins Ouma
BACKGROUND: Naturally-acquired immunity to Plasmodium falciparum malaria develops after several episodes of infection. Fc gamma receptors (FcγRs) bind to immunoglobulin G (IgG) antibodies and mediate phagocytosis of opsonized microbes, thereby, linking humoral and cellular immunity. FcγR polymorphisms influence binding affinity to IgGs and consequently, can influence clinical malaria outcomes. Specifically, variations in FcγRIIA -131Arg/His, FcγRIIIA-176F/V and FcγRIIIB-NA1/NA2 modulate immune responses through altered binding preferences to IgGs and immune complexes...
April 20, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28427357/haplotype-of-non-synonymous-mutations-within-il-23r-is-associated-with-susceptibility-to-severe-malaria-anemia-in-a-p-falciparum-holoendemic-transmission-area-of-kenya
#11
Elly O Munde, Evans Raballah, Winnie A Okeyo, John M Ong'echa, Douglas J Perkins, Collins Ouma
BACKGROUND: Improved understanding of the molecular mechanisms involved in pediatric severe malarial anemia (SMA) pathogenesis is a crucial step in the design of novel therapeutics. Identification of host genetic susceptibility factors in immune regulatory genes offers an important tool for deciphering malaria pathogenesis. The IL-23/IL-17 immune pathway is important for both immunity and erythropoiesis via its effects through IL-23 receptors (IL-23R). However, the impact of IL-23R variants on SMA has not been fully elucidated...
April 20, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28425671/activity-based-probes-for-hect-e3-ubiquitin-ligases
#12
Robert Byrne, Thomas Mund, Julien D F Licchesi
Activity-based probes (ABPs) have been used to dissect the biochemical/structural properties and cellular functions of deubiquitinases. However, their utility in studying cysteine-based E3 ubiquitin ligases has been limited. In this study, we evaluate the use of ubiquitin-ABPs (Ub-VME and Ub-PA) and a novel set of E2-Ub-ABPs on a panel of HECT E3 ubiquitin ligases. Our in vitro data show that ubiquitin-ABPs can label HECT domains. We also provide the first evidence that, in addition to the RBR E3 ubiquitin ligase Parkin, E2-Ub-ABPs can also label the catalytic HECT domains of NEDD4, UBE3C, and HECTD1...
April 20, 2017: Chembiochem: a European Journal of Chemical Biology
https://www.readbyqxmd.com/read/28405602/cognitive-evaluation-in-liver-transplant-patients-under-calcineurin-inhibitor-maintenance-therapy
#13
Nils Heits, Dalibor Keserovic, Niclas Mund, Nicola Ehmke, Alexander Bernsmeier, Alexander Hendricks, Rainer Gunther, Karsten Witt, Thomas Becker, Felix Braun
BACKGROUND: Neurological disorders due to calcineurin inhibitor (CNI) treatment pose a well-known problem after liver transplantation (LTx). In this study, the impact of CNIs on cognitive functioning during maintenance therapy was analyzed. A possible improvement of cognitive functioning, compliance and health-related quality of life (HRQoL) after conversion to a once-daily tacrolimus formulation was prospectively assessed. METHODS: In a cross-section analysis cognitive functioning of living donors (LD), waiting list patients and LTx patients was tested using a 4 times trail making test (4-TTMT)...
April 2017: Transplantation Direct
https://www.readbyqxmd.com/read/28390282/evaluation-of-efficient-glucose-release-using-sodium-hydroxide-and-phosphoric-acid-as-pretreating-agents-from-the-biomass-of-sesbania-grandiflora-l-pers-a-fast-growing-tree-legume
#14
Nitesh K Mund, Debabrata Dash, Chitta R Barik, Vaibhav V Goud, Lingaraj Sahoo, Prasannajit Mishra, Nihar R Nayak
Sesbania grandiflora (L.) Pers. is one of the fast growing tree legumes having the efficiency to produce around 50tha(-1) above ground dry matters in a year. In this study, biomass of 2years old S. grandiflora was selected for the chemical composition, pretreatments and enzymatic hydrolysis studies. The stem biomass with a wood density of 3.89±0.01gmcm(-3) contains about 38% cellulose, 12% hemicellulose and 28% lignin. Enzymatic hydrolysis of pretreated biomass revealed that phosphoric acid (H3PO4) pretreated samples even at lower cellulase loadings [1 Filter Paper Units (FPU)], could efficiently convert about 86% glucose, while, even at higher cellulase loadings (60FPU) alkali pretreated biomass could convert only about 58% glucose...
July 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28374685/zn-vi-quasiparticle-gaps-and-optical-spectra-from-many-body-calculations
#15
A Riefer, N Weber, J Mund, D R Yakovlev, M Bayer, Arno Schindlmayr, C Meier, W G Schmidt
The electronic band structures of hexagonal ZnO and cubic ZnS, ZnSe, and ZnTe compounds are determined within hybrid-density-functional theory and quasiparticle calculations. It is found that the band-edge energies calculated on the [Formula: see text] (Zn chalcogenides) or GW (ZnO) level of theory agree well with experiment, while fully self-consistent QSGW calculations are required for the correct description of the Zn 3d bands. The quasiparticle band structures are used to calculate the linear response and second-harmonic-generation (SHG) spectra of the Zn-VI compounds...
June 1, 2017: Journal of Physics. Condensed Matter: An Institute of Physics Journal
https://www.readbyqxmd.com/read/28367630/dynamic-evolution-from-negative-to-positive-photocharging-in-colloidal-cds-quantum-dots
#16
Donghai Feng, Dmitri R Yakovlev, Victor V Pavlov, Anna V Rodina, Elena V Shornikova, Johannes Mund, Manfred Bayer
The optical properties of colloidal semiconductor nanocrystals are largely influenced by the trapping of charge carriers on the nanocrystal surface. Different concentrations of electron and hole traps and different rates of their capture to the traps provide dynamical charging of otherwise neutral nanocrystals. We study the photocharging formation and evolution dynamics in CdS colloidal quantum dots with native oleic acid surface ligands. A time-resolved technique with three laser pulses (pump, orientation, and probe) is developed to monitor the photocharging dynamics with picosecond resolution on wide time scales ranging from picoseconds to milliseconds...
April 7, 2017: Nano Letters
https://www.readbyqxmd.com/read/28299842/electroacupuncture-promotes-central-nervous-system-dependent-release-of-mesenchymal-stem-cells
#17
Tatiana E Salazar, Matthew R Richardson, Eleni Beli, Matthew S Ripsch, John George, Youngsook Kim, Yaqian Duan, Leni Moldovan, Yuanqing Yan, Ashay Bhatwadekar, Vaishnavi Jadhav, Jared A Smith, Susan McGorray, Alicia L Bertone, Dmitri O Traktuev, Keith L March, Luis M Colon-Perez, Keith G Avin, Emily Sims, Julie A Mund, Jamie Case, Xiaolin Deng, Min Su Kim, Bruce McDavitt, Michael E Boulton, Jeffrey Thinschmidt, Sergio Li Calzi, Stephanie D Fitz, Robyn K Fuchs, Stuart J Warden, Todd McKinley, Anantha Shekhar, Marcelo Febo, Phillip L Johnson, Lung-Ji Chang, Zhanguo Gao, Mikhail G Kolonin, Song Lai, Jingfeng Ma, Xinzhong Dong, Fletcher A White, Huisheng Xie, Mervin C Yoder, Maria B Grant
Electroacupuncture (EA) performed in rats and humans using limb acupuncture sites, LI-4 and LI-11, and GV-14 and GV-20 (humans) and Bai-hui (rats) increased functional connectivity between the anterior hypothalamus and the amygdala and mobilized mesenchymal stem cells (MSCs) into the systemic circulation. In human subjects, the source of the MSC was found to be primarily adipose tissue, whereas in rodents the tissue sources were considered more heterogeneous. Pharmacological disinhibition of rat hypothalamus enhanced sympathetic nervous system (SNS) activation and similarly resulted in a release of MSC into the circulation...
May 2017: Stem Cells
https://www.readbyqxmd.com/read/28224607/a-giant-among-dwarfs-a-new-species-of-galago-primates-galagidae-from-angola
#18
Magdalena S Svensson, Elena Bersacola, Michael S L Mills, Rachel A Munds, Vincent Nijman, Andrew Perkin, Judith C Masters, Sébastien Couette, K Anne-Isola Nekaris, Simon K Bearder
OBJECTIVES: Based on vocalization recordings of an unknown galago species, our main objectives were to compare morphology and call structure with known closely-related taxa and describe a new species of galago. MATERIALS AND METHODS: We conducted field surveys in three forest habitats along the escarpment region in western Angola (Kumbira Forest, Bimbe Area, and Northern Scarp Forest), and examined galago specimens from museums worldwide. We digitized and analyzed calls using Avisoft SASLab Pro software...
May 2017: American Journal of Physical Anthropology
https://www.readbyqxmd.com/read/28028430/a-child-with-debilitating-pruritus
#19
Nikhil Sonthalia, Samit S Jain, Vinay B Pawar, Vinay G Zanwar, Ravindra G Surude, Pravin M Rathi, Kshitij K Munde, Sandeep Bavdekar
We describe a case of two-year-old boy presenting with debilitating pruritus, patchy alopecia and jaundice since the age of 6 months. On evaluation he had intrahepatic cholestasis with persistently raised serum alkaline phosphatase, normal Gamma glutamyl transferase and raised serum bile acid levels. His liver biopsy showed bland cholestasis and electron microscopy showed granular bile suggestive of progressive familial intrahepatic cholestasis type I. Medical therapy with ursodeoxycholic acid, cholestyramine, rifampicin with nutritional modification was successful in alleviating the symptoms and correcting the nutritional status...
October 24, 2016: Clinics and Practice
https://www.readbyqxmd.com/read/27925565/consistency-will-save-lives
#20
Sonia Munde
The term 'blue inhaler' has been synonymous with asthma patients' reliever medication for many years. It's an example of clear, simple, consistent health messaging that is used widely and successfully by people with asthma and healthcare professionals.
December 7, 2016: Nursing Standard
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