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https://www.readbyqxmd.com/read/29354973/-effects-of-ginger-separated-moxibustion-at-baliao-points-combined-with-bushen-huoxue-formula-on-patients-with-decreased-ovarian-reserve-function
#1
Duosheng Jiang, Yingchun Zhang, Xiaolan Wu, Yanming Wang, Qiangfang Fan, Song Wu
OBJECTIVE: To compare the efficacy differences between ginger-separated moxibustion at Baliao points combined with Bushen Huoxue formula and Bushen Huoxue formula alone on patients with decreased ovarian reserve function. METHODS: Fifty patients of decreased ovarian reserve function were randomly divided into an observation group and a control group, 25 cases in each one. The patients in the observation group were treated with ginger-separated moxibustion at Baliao points combined with Bushen Huoxue formula; the moxibustion was given for 1...
October 12, 2017: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
https://www.readbyqxmd.com/read/29354933/-clinical-therapeutic-effects-of-acupuncture-combined-with-chinese-herbal-medicine-on-infertility-of-polycystic-ovary-syndrome-in-the-patients-with-ovulation-induction-with-letrozole
#2
Yan Yin, Yingchun Zhang, Hua Zhang, Duosheng Jiang, Guirong Guo
OBJECTIVE: To evaluate the clinical therapeutic effects and safety on infertility of polycystic ovary syndrome (PCOS) in the patients with ovulation induction with letrozole in the treatment with the formula for regulating menstruation and removing phlegm and electroacupuncture (EA). METHODS: A total of 120 patients of PCOS infertility were randomized into 3 groups, 40 cases in each one. In the group A, diane-35 was prescribed for oral administration (one tablet a day since the 5th day of menstruation, continuously for 21 days)...
January 12, 2018: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
https://www.readbyqxmd.com/read/29350886/the-cell-biology-and-molecular-genetics-of-m%C3%A3-llerian-duct-development
#3
REVIEW
Zahida Yesmin Roly, Brendan Backhouse, Andrew Cutting, Tiong Yang Tan, Andrew H Sinclair, Katie L Ayers, Andrew T Major, Craig A Smith
The Müllerian ducts are part of the embryonic urogenital system. They give rise to mature structures that serve a critical function in the transport and development of the oocyte and/or embryo. In most vertebrates, both sexes initially develop Müllerian ducts during embryogenesis, but they regress in males under the influence of testis-derived Anti-Müllerian Hormone (AMH). A number of regulatory factors have been shown to be essential for proper duct development, including Bmp and Wnt signaling molecules, together with homeodomain transcription factors such as PAX2 and LIM1...
January 19, 2018: Wiley Interdisciplinary Reviews. Developmental Biology
https://www.readbyqxmd.com/read/29345168/mother-s-age-at-menopause-but-not-own-age-at-menarche-has-an-impact-on-ovarian-reserve
#4
Jessika Moreau, Nicolas Gatimel, Clémentine Cohade, Jean Parinaud, Roger Léandri
To detect clinical parameters impacting ovarian reserve, data were analyzed from 573 patients who had an anti-Müllerian hormone (AMH) measurement for infertility treatment. No impact was found on the age at menarche but a significant diminished ovarian reserve was observed when a patient's mother was menopausal before age 50. These data suggest that ovarian reserve must be monitored in such patients to offer them fertility preservation when at risk of premature ovarian insufficiency (POI).
January 18, 2018: Gynecological Endocrinology
https://www.readbyqxmd.com/read/29345163/low-dose-hp-hmg-in-an-antagonist-protocol-for-ivf-in-ovulatory-and-anovulatory-patients-with-high-amh
#5
Negjyp Sopa, Elisabeth Clare Larsen, Anders Nyboe Andersen
Women with high-AMH levels have an increased risk of ovarian hyperstimulation syndrome (OHSS). Studies have suggested that highly purified menotropin (HP-hMG) Menopur® reduces the risk. We, therefore, studied use of low-dose (112.5 IU/day) HP-hMG in ovulatory and anovulatory patients with high AMH (>32 pmol/L). The primary endpoint was the distribution of patients with appropriate, excessive, and inadequate response (5-14, ≥15, and ≤4 oocytes). Another endpoint was frequency of OHSS. Totally 115 women were included and 78 (67...
January 18, 2018: Gynecological Endocrinology
https://www.readbyqxmd.com/read/29332065/a-novel-mutation-of-amhr2-in-two-siblings-with-persistent-m%C3%A3-llerian-duct-syndrome
#6
Aydilek D Çakır, Hande Turan, Hüseyin Onay, Haluk Emir, Senol Emre, Nil Comunoglu, Oya Ercan, Olcay Evliyaoglu
Persistent müllerian duct syndrome (PMDS) is characterized by the presence of müllerian duct derivatives in otherwise phenotypically normal males. It is caused in approximately 85% of the cases by mutations in the AMH gene or its type II receptor (AMHR2). We report on 2 brothers with normal external genitalia but high serum AMH levels. Sequence analysis of the AMHR2 gene in the 2 siblings revealed a novel homozygous missense mutation in exon 10 (p.V458L, c.1372G>T). PMDS is a rare condition, but it has to be considered in differential diagnosis of cryptorchidism with normal male genitalia...
January 13, 2018: Sexual Development: Genetics, Molecular Biology, Evolution, Endocrinology, Embryology, and Pathology of Sex Determination and Differentiation
https://www.readbyqxmd.com/read/29331755/sphingosine-1-phosphate-protects-human-ovarian-follicles-from-apoptosis-in-vitro
#7
Yilmaz Guzel, Gamze Bildik, Ozgur Oktem
OBJECTIVE(S): We aimed to analyze if anti-apoptotic agent sphingosine-1-phosphate offers protection against in vitro follicle atresia during culture of human ovarian cortical samples. STUDY DESIGN: A translational research study of ex-vivo and in-vitro models of human ovarian tissue. MATERIAL AND METHODS: Ovarian cortical tissue fragments (1 × 0.5 cm) were obtained from young patients (n = 15 mean age ± SD: 29.4 ± 2.5) undergoing laparoscopic excision of benign ovarian cysts...
January 6, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29331235/antim%C3%A3-llerian-hormone-as-a-predictor-of-live-birth-following-assisted-reproduction-an-analysis-of-85-062-fresh-and-thawed-cycles-from-the-society-for-assisted-reproductive-technology-clinic-outcome-reporting-system-database-for-2012-2013
#8
Reshef Tal, David B Seifer, Ethan Wantman, Valerie Baker, Oded Tal
OBJECTIVE: To determine if serum antimüllerian hormone (AMH) is associated with and/or predictive of live birth assisted reproductive technology (ART) outcomes. DESIGN: Retrospective analysis of Society for Assisted Reproductive Technology Clinic Outcome Reporting System database from 2012 to 2013. SETTING: Not applicable. PATIENT(S): A total of 69,336 (81.8%) fresh and 15,458 (18.2%) frozen embryo transfer (FET) cycles with AMH values...
January 11, 2018: Fertility and Sterility
https://www.readbyqxmd.com/read/29325736/differential-association-of-dennd1agenetic-variants-with-polycystic-ovary-syndrome-in-tunisian-but-not-bahraini-arab-women
#9
Meriem Dallel, Sameh Sarray, Zeineb Douma, Feten Hachani, Abrar K Al-Ansari, Dhafer B Letaifa, Touhami Mahjoub, Wassim Y Almawi
BACKGROUND AND AIM: Polycystic ovary syndrome (PCOS) is a common endocrine disorder, and results from interaction between modifiable and non-modifiable factors, including genetic predisposition. Previous genome-wide association studies and meta-analysis identified DENND1A as PCOS susceptibility locus in some, but not all populations. We investigated whether the association of DENND1A gene variants with PCOS was similar between Tunisian and Bahraini Arab women. SUBJECTS AND METHODS: This was retrospective case-control study...
January 8, 2018: Gene
https://www.readbyqxmd.com/read/29325695/investigation-of-the-uterine-structural-changes-in-the-experimental-model-with-polycystic-ovary-syndrome-and-effects-of-vitamin-d-treatment-an-ultrastructural-and-immunohistochemical-study
#10
Yurdun Kuyucu, Latife Seyran Çelik, Özge Kendirlinan, Özgül Tap, Ufuk Özgü Mete
In this study, we aimed to investigate the structural changes seen in the endometrium in experimental PCOS rat model and the effects of vitamin D treatment on these changes at immunohistochemical and electron microscopic levels. 24 prepubertal female rats were divided into three groups. Two groups were injected with dehydroepiandrosterone and one of them was treated with 1,25(OH)2 D3 at the same time. The control group was injected with sesame oil. At the end of the 28th day, the blood samples were collected...
January 8, 2018: Reproductive Biology
https://www.readbyqxmd.com/read/29315564/circulating-anti-m%C3%A3-llerian-hormone-and-breast-cancer-risk-a-study-in-ten-prospective-cohorts
#11
Wenzhen Ge, Tess V Clendenen, Yelena Afanasyeva, Karen L Koenig, Claudia Agnoli, Louise A Brinton, Joanne F Dorgan, A Heather Eliassen, Roni T Falk, Göran Hallmans, Susan E Hankinson, Judith Hoffman-Bolton, Timothy J Key, Vittorio Krogh, Hazel B Nichols, Dale P Sandler, Minouk J Schoemaker, Patrick M Sluss, Malin Sund, Anthony J Swerdlow, Kala Visvanathan, Mengling Liu, Anne Zeleniuch-Jacquotte
A strong positive association has been observed between circulating anti-Müllerian hormone (AMH), a biomarker of ovarian reserve, and breast cancer risk in three prospective studies. Confirming this association is important because of the paucity of biomarkers of breast cancer risk in premenopausal women. We conducted a consortium study including ten prospective cohorts that had collected blood from premenopausal women. A nested case-control design was implemented within each cohort. A total of 2,835 invasive (80%) and in situ (20%) breast cancer cases were individually matched to controls (n = 3,122) on age at blood donation...
January 8, 2018: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/29315373/female-offspring-from-chronic-hyperandrogenemic-dams-exhibit-delayed-puberty-and-impaired-ovarian-reserve
#12
Zhiqiang Wang, Mingjie Shen, Ping Xue, Sara A DiVall, James Segars, Sheng Wu
Female offspring of many species exposed to high doses of androgens in utero experience endocrine dysfunction during adulthood. The phenotype of offspring from females with pre-pregnancy hyperandrogenemia and impaired ovulation, however, has not been examined. We developed a mouse model of hyperandrogenemia by implanting a low dose dihydrotestosterone (DHT) pellet 15 days before conception. The serum DHT levels in dams treated with the pellet were 1.7 to 2 fold higher (p<0.005) than levels in dams without DHT...
January 5, 2018: Endocrinology
https://www.readbyqxmd.com/read/29314138/ovarian-markers-and-irregular-menses-among-women-with-type-1-diabetes-in-the-epidemiology-of-diabetes-interventions-and-complications-study
#13
C Kim, R S Miller, B H Braffett, Y Pan, V L Arends, A K Saenger, A Barnie, A V Sarma
OBJECTIVE: Women with type 1 diabetes have increased risk of infertility compared to women without diabetes even after adjustment for irregular menses, but etiologies are incompletely understood. Our aim was to examine the prevalence of abnormalities in ovarian markers consistent with polycystic ovary syndrome in women with type 1 diabetes and associations with irregular menses and diabetes-specific variables. DESIGN, PATIENTS, AND MEASUREMENTS: We conducted a secondary analysis of women in the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Study (DCCT/EDIC), a randomized trial and observational follow-up of intensive insulin therapy for type 1 diabetes...
January 4, 2018: Clinical Endocrinology
https://www.readbyqxmd.com/read/29306180/predictive-value-of-antral-follicle-count-and-serum-anti-m%C3%A3-llerian-hormone-which-is-better-for-live-birth-prediction-in-patients-aged-over-40-with-their-first-ivf-treatment
#14
Yubin Lee, Tae Hyung Kim, Jae Kyun Park, Jin Hee Eum, Hee Jun Lee, Jayeon Kim, Sang Woo Lyu, You Shin Kim, Woo Sik Lee, Tae Ki Yoon
OBJECTIVE: To evaluate clinical utility of antral follicle count (AFC) and anti-Müllerian hormone (AMH) in predicting in vitro fertilization (IVF) outcomes among the patients over 40 years old in their first IVF cycles. STUDY DESIGN: Total 219 patients aged 40 or older who underwent their first IVF with gonadotropin-releasing hormone antagonist protocol from January 2013 to September 2014 in CHA Gangnam fertility center were retrospectively analyzed. AFC and serum samples were measured prior to IVF treatment...
December 29, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29305800/suspected-ontogeny-of-a-recently-described-hypo-androgenic-pcos-like-phenotype-with-advancing-age
#15
Norbert Gleicher, Vitaly A Kushnir, Sarah K Darmon, Qi Wang, Lin Zhang, David F Albertini, David H Barad
BACKGROUND: A recent report described a new PCOS-like phenotype in lean older infertile women, and was characterized by high age-specific anti-Müllerian hormone (AMH) but hypo- rather than the expected hyper-androgenism. The hypo-androgenism was, furthermore, characterized of, likely, adrenal origin and autoimmune etiology. PATIENTS AND METHODS: We extracted data on 708 consecutive infertility patients, and separated them into three age-strata, <35, 36-42, and >42 years...
January 6, 2018: Endocrine
https://www.readbyqxmd.com/read/29302874/anti-m%C3%A3-llerian-hormone-in-pre-menopausal-females-after-ablative-radioiodine-treatment-for-differentiated-thyroid-cancer
#16
Massimo Giusti, Miranda Mittica, Paola Comite, Claudia Campana, Stefano Gay, Michele Mussap
PURPOSE: In recent years, anti-Mullerian hormone (AMH) has been considered a reliable index of ovarian reserve. There are few data on AMH values in thyroid cancer. The aim of this study was to evaluate AMH levels in pre-menopausal women with a history of low-risk thyroid cancer. METHODS: Thirty-four women (aged 40.7 ± 6.7 years) were studied 7.1 ± 0.9 years after surgery and at least one RAI treatment. A group of 23 thyroid cancer women (41.6 ± 7...
January 4, 2018: Endocrine
https://www.readbyqxmd.com/read/29297967/levothyroxine-supplementation-improves-serum-anti-m%C3%A3-llerian-hormone-levels-in-infertile-patients-with-hashimoto-s-thyroiditis
#17
Masako Kuroda, Keiji Kuroda, Tomoya Segawa, Jaeduk Y Noh, Ai Yoshihara, Koichi Ito, Hisao Osada, Satoru Takeda, Shokichi Teramoto
AIM: Thyroid dysfunction and autoimmunity are associated with an adverse effect on fertility. An aberrant high thyroid stimulating hormone level is associated with diminished ovarian reserve in women of reproductive age; however, the utility of levothyroxine (LT4) replacement for infertile patients with subclinical hypothyroidism is still under discussion. The aim of this study was to investigate whether LT4 supplementation for infertile patients with subclinical hypothyroidism improves impaired ovarian function...
January 3, 2018: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/29296171/micrornas-sequencing-unveils-distinct-molecular-subgroups-of-plasmablastic-lymphoma
#18
Maria Raffaella Ambrosio, Lucia Mundo, Sara Gazaneo, Matteo Picciolini, Prasad Satya Vara, Shaheen Sayed, Alessandro Ginori, Giuseppe Lo Bello, Leonardo Del Porro, Mohsen Navari, Stefano Ascani, Amhed Yonis, Lorenzo Leoncini, Pier Paolo Piccaluga, Stefano Lazzi
Plasmablastic lymphoma (PBL) is an aggressive lymphoma, often arising in the context of immunodeficiency and associated with Epstein-Barr virus (EBV) infection. The most frequently detected genetic alteration is the deregulation of MYC gene through the translocation - t(8;14)(q24;q32). The diagnosis of PBL is often challenging because it has an overlap in morphology, immunophenotype, cytogenetics and virus association with other lymphomas and plasma cell neoplasms; further, its molecular basis remains elusive...
December 8, 2017: Oncotarget
https://www.readbyqxmd.com/read/29285121/persistent-m%C3%A3-llerian-duct-syndrome-a-case-report-and-review
#19
Xiaoya Ren, Di Wu, Chunxiu Gong
Persistent Müllerian duct syndrome (PMDS) is a rare type of male pseudohermaphroditism caused by a deficiency in anti-Müllerian hormone (AMH) or a defect in its type II receptor. The current study reports the clinical data and results of the genetic analysis of a 17-month-old male diagnosed with PMDS. The clinical manifestations of the patient included a left transverse testicular ectopia and bilateral cryptorchidism. Pelvic ultrasonography indicated two testes on the same left inguinal ring and left inguinal hernia and uterine tissue located at the left rear of the bladder...
December 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29279199/anti-m%C3%A3-llerian-hormone-amh-antral-follicle-count-afc-external-morphometrics-and-fertility-in-tabapu%C3%A3-cows
#20
Renata Maculan, Tássia Louregiani Carvalho Pinto, Gabriel Miranda Moreira, Gisvani Lopes de Vasconcelos, Jesus Afonso Sanches, Ricardo Garcia Rosa, Rafael Ribeiro Bonfim, Tarcisio de Moraes Gonçalves, José Camisão de Souza
The intense selection of characteristics related to animal performance may affect the reproductive efficiency of beef cows negatively. Selection for fertility along with production traits is, therefore, readily justifiable. The objective of the present study was to evaluate possible relationships among AFC, serum AMH concentrations and external morphometrics with reproductive efficiency in Tabapuã (a Brazilian Bos indicus beef breed) females. Antral follicle counts and external morphometrics were measured in nulliparous (n = 162), primiparous (n = 80) and multiparous (n = 351) cows, from four farms...
December 23, 2017: Animal Reproduction Science
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