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Direct observation of residents

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https://www.readbyqxmd.com/read/29457871/a-qtl-on-chromosome-1-modulates-inter-male-aggression-in-mice
#1
Anna Delprato, Brice Bonheur, Marie-Paule Algéo, Alba Murillo, Esha Dhawan, Lu Lu, Robert W Williams, Wim E Crusio
Aggression between male conspecifics is a complex social behavior that is likely modulated by multiple gene variants. In this study the BXD recombinant inbred mouse strains (RIS) were used to map quantitative trait loci (QTLs) underlying behaviors associated with intermale aggression. Four hundred and fifty-seven males from 55 strains (including the parentals) were observed at an age of 13 +/- 1 week in a resident-intruder test following 10 days of isolation. Attack latency was measured directly within a 10 minute time period and the test was repeated 24 hours later...
February 19, 2018: Genes, Brain, and Behavior
https://www.readbyqxmd.com/read/29451517/-burden-of-diverticular-disease-an-observational-analysis-based-on-italian-real-world-data
#2
Francesco Saverio Mennini, Paolo Sciattella, Andrea Marcellusi, Bernardo Toraldo, Maurizio Koch
INTRODUCTION: Diverticular disease (DD) represent a wide variety of conditions associated with the presence of diverticula in the colon. The most serious form is an acute episode of diverticulitis which can lead to hospitalization and surgery with various types of consequences. The main aim of this study was to evaluate, from both cross-sectional and longitudinal perspective, the economic burden of diverticulitis in the real practice. METHOD: A deterministic linkage was performed at individual user level between the different administrative sources of the Marche Region through anonymised ID number for a period of analysis between 1 January 2008 and 31 December 2014...
January 2018: Recenti Progressi in Medicina
https://www.readbyqxmd.com/read/29450196/recruitment-and-lessons-learned-from-a-community-based-intervention-program-the-learning-families-project-in-hong-kong
#3
Joanna T W Chu, Alice Wan, Sunita M Stewart, Kwok Tung Ng, Tai Hing Lam, Sophia S Chan
Background: Recruitment is central to any research project, and recruitment itself should be well documented and researched. We describe our recruitment efforts for a community-based research project-entitled the Learning Families Project-conducted in Hong Kong. Methods: In collaboration with community stakeholders, residents from a public housing estate were recruited to participate in family programs aimed at enhancing family well-being. Various recruitment strategies were employed including the distribution of 19,200 leaflets, 688 posters, a banner, a kick-off ceremony, 10 promotion activities, 1,000 direct calls, word of mouth, 51 mobile counters, and 10 door-to-door visits...
2018: Frontiers in Public Health
https://www.readbyqxmd.com/read/29442533/variation-of-care-time-between-nursing-units-in-classification-based-nurse-to-resident-ratios-a-multilevel-analysis
#4
Albert Brühl, Katarina Planer, Anja Hagel
A validity test was conducted to determine how care level-based nurse-to-resident ratios compare with actual daily care times per resident in Germany. Stability across different long-term care facilities was tested. Care level-based nurse-to-resident ratios were compared with the standard minimum nurse-to-resident ratios. Levels of care are determined by classification authorities in long-term care insurance programs and are used to distribute resources. Care levels are a powerful tool for classifying authorities in long-term care insurance...
January 2018: Inquiry: a Journal of Medical Care Organization, Provision and Financing
https://www.readbyqxmd.com/read/29432623/a-time-motion-study-of-primary-care-physicians-work-in-the-electronic-health-record-era
#5
Richard A Young, Sandra K Burge, Kaparaboyna A Kumar, Jocelyn M Wilson, Daniela F Ortiz
BACKGROUND AND OBJECTIVES: Electronic health records (EHRs) have had mixed effects on the workflow of ambulatory primary care. In this study, we update previous research on the time required to care for patients in primary care clinics with EHRs. METHODS: We directly observed family physician (FP) attendings, residents, and their ambulatory patients in 982 visits in clinics affiliated with 10 residencies of the Residency Research Network of Texas. The FPs were purposely chosen to reflect a diversity of patient care styles...
February 2018: Family Medicine
https://www.readbyqxmd.com/read/29428403/the-sonic-hedgehog-signaling-pathway-regulates-inferior-alveolar-nerve-regeneration
#6
Yurie Yamada, Atsushi Ohazama, Takeyasu Maeda, Kenji Seo
Activation of Shh signaling is known to be observed following injury of the peripheral nerves such as the sciatic nerve. However, the precise role of Shh signaling during peripheral nerve regeneration is not fully understood. The inferior alveolar nerve (IAN) is most commonly injured during oral surgery. Unlike the sciatic nerve, the IAN is isolated from other craniofacial tissues, as it resides in a long bony canal within the mandible. The IAN is thus an excellent experimental model for investigating peripheral nerve regeneration...
February 8, 2018: Neuroscience Letters
https://www.readbyqxmd.com/read/29427264/urban-renewal-mega-projects-and-residents-quality-of-life-evidence-from-historical-religious-center-of-mashhad-metropolis
#7
Amir Forouhar, Mahnoosh Hasankhani
Urban decay is the process by which a historical city center, or an old part of a city, falls into decrepitude and faces serious problems. Urban management, therefore, implements renewal mega projects with the goal of physical and functional revitalization, retrieval of socioeconomic capacities, and improving of quality of life of residents. Ignoring the complexities of these large-scale interventions in the old and historical urban fabrics may lead to undesirable consequences, including an additional decline of quality of life...
February 9, 2018: Journal of Urban Health: Bulletin of the New York Academy of Medicine
https://www.readbyqxmd.com/read/29426370/patient-delay-in-seeking-tuberculosis-diagnosis-and-associated-factors-in-hadiya-zone-southern-ethiopia
#8
Terefe Gone Fuge, Solomon Gebre Bawore, Deneke Wolde Solomon, Tadele Yohannes Hegana
OBJECTIVE: To assess patient delay in seeking tuberculosis diagnosis and associated factors in Hadiya Zone, Southern Ethiopia. RESULTS: The median patient delay in tuberculosis diagnosis in Hadiya Zone was found to be 30 days. Socioeconomic and perception related factors were identified as independent predictors for tuberculosis diagnosis delay. Socioeconomic characteristics like urban residence [OR 2.36; CI 1.64-3.40], religious views [OR 1.24; CI 1.73-7.0], low monthly income [OR 3...
February 9, 2018: BMC Research Notes
https://www.readbyqxmd.com/read/29416331/pharmacokinetics-and-in-vitro-in-vivo-antitumor-efficacy-of-aptamer-targeted-ecoflex-%C3%A2-nanoparticles-for-docetaxel-delivery-in-ovarian-cancer
#9
Erfaneh Ghassami, Jaleh Varshosaz, Ali Jahanian-Najafabadi, Mohsen Minaiyan, Parvin Rajabi, Effat Hayati
Purpose: Epithelixal ovarian cancer is the fourth cause of cancer death in developed countries with 77% of ovarian cancer cases diagnosed with regional or distant metastasis, with poor survival rates. Docetaxel (DTX) is a well-known anticancer agent, with clinically proven efficacy in several malignancies, including ovarian cancer. However, the adverse effects caused by the active ingredient or currently marketed formulations could even deprive the patient of the advantages of treatment...
2018: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/29413393/the-broken-lens-of-bpsd-why-we-need-to-rethink-the-way-we-label-the-behavior-of-people-who-live-with-alzheimer-disease
#10
Susan Macaulay
For the past 20 years, the behaviors of people who live with dementia (PLWD) that others find challenging or problematic have primarily been ascribed to Alzheimer disease and related dementias and have been assessed through the biomedical lens of Behavioral and Psychological Symptoms of Dementia (BPSD). This has led to the root causes of these behaviors being overlooked, which in turn leaves them unaddressed. Further, using the artificial construct of BPSD has led to many PLWD being inappropriately prescribed (off-label) medications that are largely ineffective in resolving the behaviors because they do nothing to remedy the underlying psychosocial and environmental causes...
February 2018: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/29402650/a-quality-improvement-system-to-manage-feeding-assistance-care-in-assisted-living
#11
Sandra F Simmons, Chris S Coelho, Andrew Sandler, John F Schnelle
PURPOSE: To describe a feasible quality improvement system to manage feeding assistance care processes in an assisted living facility (ALF) that provides dementia care and the use of these data to maintain the quality of daily care provision and prevent unintentional weight loss. DESIGN AND METHODS: Supervisory ALF staff used a standardized observational protocol to assess feeding assistance care quality during and between meals for 12 consecutive months for 53 residents receiving dementia care...
February 2, 2018: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/29390564/the-associations-of-stroke-transient-ischemic-attack-and-or-stroke-related-recurrent-vascular-events-with-lipoprotein-associated-phospholipase-a2-a-systematic-review-and-meta-analysis
#12
Ye Tian, Huan Jia, Sichen Li, Yanmin Wu, Li Guo, Guojun Tan, Bin Li
BACKGROUND: Studies on stroke and lipoprotein-associated phospholipase A2 (Lp-PLA2) have produced conflicting results. OBJECTIVE: The aim of the study was to assess the associations of Lp-PLA2 levels (mass and activity) with recurrent vascular events in patients with transient ischemic attack (TIA) and/or first ischemic stroke and with stroke in the general population. METHODS: The MEDLINE, Embase, the Cochrane Library, Web of Science, Science Direct, China National Knowledge Infrastructure, China Biology Medical Disc (CBMdisc), and WanFang were searched for prospective observational studies reported until January 2017...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29385710/a-review-of-the-catalytic-mechanism-of-human-manganese-superoxide-dismutase
#13
REVIEW
Jahaun Azadmanesh, Gloria E O Borgstahl
Superoxide dismutases (SODs) are necessary antioxidant enzymes that protect cells from reactive oxygen species (ROS). Decreased levels of SODs or mutations that affect their catalytic activity have serious phenotypic consequences. SODs perform their bio-protective role by converting superoxide into oxygen and hydrogen peroxide by cyclic oxidation and reduction reactions with the active site metal. Mutations of SODs can cause cancer of the lung, colon, and lymphatic system, as well as neurodegenerative diseases such as Parkinson's disease and amyotrophic lateral sclerosis...
January 30, 2018: Antioxidants (Basel, Switzerland)
https://www.readbyqxmd.com/read/29385432/dynamic-and-diverse-changes-in-the-functional-properties-of-vascular-smooth-muscle-cells-in-pulmonary-hypertension
#14
Kurt R Stenmark, Maria G Frid, Brian B Graham, Rubin M Tuder
Pulmonary hypertension (PH) is the end result of interaction between pulmonary vascular tone and a complex series of cellular and molecular events termed "vascular remodeling". The remodeling process, which can involve the entirety of pulmonary arterial vasculature, almost universally involves medial thickening, driven by increased numbers and hypertrophy of its principal cellular constituent, smooth muscle cells (SMCs). It is noted, however that SMCs comprise heterogeneous populations of cells, which can exhibit markedly different proliferative, inflammatory, and extracellular matrix production changes during remodeling...
January 27, 2018: Cardiovascular Research
https://www.readbyqxmd.com/read/29385136/combining-ordinary-kriging-with-wind-directions-to-identify-sources-of-industrial-odors-in-portland-oregon
#15
Ted C Eckmann, Samantha G Wright, Logan K Simpson, Joe L Walker, Steven A Kolmes, James E Houck, Sandra C Velasquez
This study combines Ordinary Kriging, odor monitoring, and wind direction data to demonstrate how these elements can be applied to identify the source of an industrial odor. The specific case study used as an example of how to address this issue was the University Park neighborhood of Portland, Oregon (USA) where residents frequently complain about industrial odors, and suspect the main source to be a nearby Daimler Trucks North America LLC manufacturing plant. We collected 19,665 odor observations plus 105,120 wind measurements, using an automated weather station to measure winds in the area at five-minute intervals, logging continuously from December 2014 through November 2015, while we also measured odors at 19 locations, three times per day, using methods from the American Society of the International Association for Testing and Materials...
2018: PloS One
https://www.readbyqxmd.com/read/29379973/reducing-patient-no-shows-an-initiative-at-an-integrated-care-teaching-health-center
#16
Ashwin Mehra, Claire J Hoogendoorn, Greg Haggerty, Jessica Engelthaler, Stephen Gooden, Michelle Joseph, Shannon Carroll, Peter A Guiney
Background: Patient no-shows impede the effectiveness and efficiency of health care services delivery. Objective: To evaluate a 2-phase intervention to reduce no-show rates at an integrated care community health center that incorporates a teaching program for osteopathic family medicine residents. Methods: The Elmont Teaching Health Center (ETHC) is 1 of 5 community-based health centers comprising the Long Island Federally Qualified Health Centers...
February 1, 2018: Journal of the American Osteopathic Association
https://www.readbyqxmd.com/read/29341682/gate-controlled-spin-valley-locking-of-resident-carriers-in-wse_-2-monolayers
#17
P Dey, Luyi Yang, C Robert, G Wang, B Urbaszek, X Marie, S A Crooker
Using time-resolved Kerr rotation, we measure the spin-valley dynamics of resident electrons and holes in single charge-tunable monolayers of the archetypal transition-metal dichalcogenide (TMD) semiconductor WSe_{2}. In the n-type regime, we observe long (∼130  ns) polarization relaxation of electrons that is sensitive to in-plane magnetic fields B_{y}, indicating spin relaxation. In marked contrast, extraordinarily long (∼2  μs) polarization relaxation of holes is revealed in the p-type regime, which is unaffected by B_{y}, directly confirming long-standing expectations of strong spin-valley locking of holes in the valence band of monolayer TMDs...
September 29, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/29335004/factors-associated-with-poor-treatment-outcome-of-tuberculosis-in-debre-tabor-northwest-ethiopia
#18
Addisu Melese, Balew Zeleke
OBJECTIVE: Directly observed treatment short course has been implemented as part of the national tuberculosis control program in Ethiopia. The strategy, as evidenced by different studies, has improved the survival and treatment success rate of tuberculosis patients. However, some patients failed to complete their treatments and the factors for this failure were not assessed in the study area. We, therefore sought to identify factors associated with poor treatment outcome of tuberculosis in Debre Tabor, northwest Ethiopia...
January 15, 2018: BMC Research Notes
https://www.readbyqxmd.com/read/29328347/as-tall-as-my-peers-similarity-in-body-height-between-migrants-and-hosts
#19
Barry Bogin, Michael Hermanussen, Christiane Scheffler
Background: We define migrants as people who move from their place of birth to a new place of residence. Migration usually is directed by "Push-Pull" factors, for example to escape from poor living conditions or to find more prosperous socio-economic conditions. Migrant children tend to assimilate quickly, and soon perceive themselves as peers within their new social networks. Differences exist between growth of first generation and second generation migrants. Methods: We review body heights and height distributions of historic and modern migrant populations to test two hypotheses: 1) that migrant and adopted children coming from lower social status localities to higher status localities adjust their height growth toward the mean of the dominant recipient social network, and 2) social dominant colonial and military migrants display growth that significantly surpasses the median height of both the conquered population and the population of origin...
January 12, 2018: Anthropologischer Anzeiger; Bericht über die Biologisch-anthropologische Literatur
https://www.readbyqxmd.com/read/29328018/-a-day-in-the-life-of-a-medical-resident-on-the-ward
#20
A R Schuurman, S A Bos, K de Wit, R de Graaf, W J Wiersinga
OBJECTIVE: To investigate how internal medicine residents allocate their time during a hospital dayshift on the wards. DESIGN: Prospective observational cohort study (time and motion study). METHODS: Data were collected from 36 internal medicine residents working at the Internal Medicine Department of the Academic Medical Centre in Amsterdam, the Netherlands. Trained observers monitored 22 residents using a newly developed smartphone-application, registering their dayshift activities (meetings and education, direct patient contact, administrative tasks, lunch/break, other) and location (workstation, conference room, ward and patient rooms, other)...
2018: Nederlands Tijdschrift Voor Geneeskunde
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