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https://www.readbyqxmd.com/read/28331366/the-effects-of-turmeric-curcumin-on-tumor-suppressor-protein-p53-and-estrogen-receptor-er%C3%AE-in-breast-cancer-cells
#1
Kelly Hallman, Katie Aleck, Brigitte Dwyer, Victoria Lloyd, Meghan Quigley, Nada Sitto, Amy E Siebert, Sumi Dinda
Curcumin (CUR) is a compound that has antibacterial, antiviral, anti-inflammatory, and anticancer properties. In this study, we have analyzed the effects of CUR on the expression of ERα and p53 in the presence of hormones and anti-hormones in breast cancer cells. Cells were cultured in a medium containing charcoal-stripped fetal bovine serum to deplete any endogenous steroids and treated with CUR at varying concentrations or in combination with hormones and anti-hormones. Protein analysis revealed a relative decrease in the levels of p53 and ERα upon treatment with 5-60 µM CUR...
2017: Breast Cancer: Targets and Therapy
https://www.readbyqxmd.com/read/28330274/evaluation-of-some-lignocellulosic-byproducts-of-food-industry-for-microbial-xylitol-production-by-candida-tropicalis
#2
Kubra Eryasar, Seda Karasu-Yalcin
Some lignocellulosic food byproducts such as potato peels, wheat bran, barley bran and chestnut shells were evaluated as potential sources of xylose for microbial xylitol production by yeasts. Potential yeast strains were selected after screening xylitol production of some indigenous yeasts in a defined fermentation medium. Candida tropicalis strains gave the highest results with 83.28 and 54.07 g/L xylitol production from 100 g/L xylose. Lignocellulosic materials were exposed to acid hydrolysis at different conditions...
December 2016: 3 Biotech
https://www.readbyqxmd.com/read/28330243/micropropagation-and-validation-of-genetic-and-biochemical-fidelity-among-regenerants-of-nothapodytes-nimmoniana-graham-mabb-employing-issr-markers-and-hplc
#3
Lokesh Prakash, Sushil Kumar Middha, Sudipta Kumar Mohanty, Mallappa Kumara Swamy
An in vitro protocol has been established for clonal propagation of Nothapodytes nimmoniana which is an important source of Camptothecin (CPT). Elite source was identified based on the chemical potency to accumulate the optimum level of CPT. Different types and concentrations of plant growth regulators were used to study their effect on inducing multiple shoots from the explants regenerated from embryos of N. nimmoniana. Of these, a combination of N6-benzyladenine (0.2 mg L(-1)) and Indole-3-butyric acid (IBA) (0...
December 2016: 3 Biotech
https://www.readbyqxmd.com/read/28319718/effect-of-environmental-exposure-on-charcoal-density-and-porosity-in-a-boreal-forest
#4
Xiaodong Gao, Laura E Driver, Isabella Kasin, Caroline A Masiello, Lacey A Pyle, Brandon Dugan, Mikael Ohlson
Although charcoal's density and porosity shape its environmental roles (e.g. controlling its landscape movement and determining the internal pore space available as microbial habitat), the rate of change of these properties in the environment remains largely unknown. With time, charcoal pores may fill or charcoal particles may shatter, altering the ecosystem services delivered. In this study we examined the effects of environmental exposure on the density and porosity of charcoals pyrolyzed at two different temperatures (350 and 520°C)...
March 16, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28318693/the-influence-of-dual-substrate-layer-extensive-green-roofs-on-rainwater-runoff-quantity-and-quality
#5
Xiaoou Wang, Yimei Tian, Xinhua Zhao
This study investigates the ability of dual-substrate-layer extensive green roofs to retain rainwater and reduce pollutant leaching. The substrates in dual-substrate-layer green roofs consist of an upper organic nutrition layer for plant growth and a lower inorganic adsorption layer for water retention and pollutant reduction. One traditional single-substrate-layer extensive green roof was built for comparison with dual-substrate-layer green roofs. During the experimental period, dual-substrate-layer green roofs supported better natural vegetation growth, with coverage exceeding 90%, while the coverage in single-substrate-layer green roof was over 80%...
March 16, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28318234/light-absorbing-brown-carbon-aerosol-constituents-from-combustion-of-indonesian-peat-and-biomass
#6
Sri Hapsari Budisulistiorini, Matthieu Riva, Michael Williams, Jing Chen, Masayuki Itoh, Jason Douglas Surratt, Mikinori Kuwata
Light-absorbing brown carbon (BrC) constituents of organic aerosol (OA) have been shown to significantly absorb ultra-violet (UV) and visible light, and thus, impact radiative forcing. However, molecular identification of the BrC constituents is still limited. In this study, we characterize BrC constituents at the molecular level in: i) aerosols emitted by combustion of peat, fern/leaf, and charcoal from Indonesia and ii) ambient aerosols collected in Singapore during the 2015 haze episode. Aerosols were analyzed using ultra-performance liquid chromatography interfaced to a diode array detector and electrospray ionization high-resolution quadrupole time-of-flight mass spectrometer (UPLC/DAD-(-)ESI-HR-QTOFMS) operated in the negative ion mode...
March 20, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28301629/antidote-availability-in-the-municipality-of-campinas-s%C3%A3-o-paulo-brazil
#7
Luciane Cristina Rodrigues Fernandes, Taís Freire Galvão, Adriana Safioti Toledo Ricardi, Eduardo Mello De Capitani, Stephen Hyslop, Fábio Bucaretchi
CONTEXT AND OBJECTIVE: The lack of availability of antidotes in emergency services is a worldwide concern. The aim of the present study was to evaluate the availability of antidotes used for treating poisoning in Campinas (SP). DESIGN AND SETTING: This was a cross-sectional study of emergency services in Campinas, conducted in 2010-2012. METHODS: The availability, amount in stock, place of storage and access time for 26 antidotal treatments was investigated...
March 13, 2017: São Paulo Medical Journal, Revista Paulista de Medicina
https://www.readbyqxmd.com/read/28299876/essential-oils-of-myrtaceae-species-growing-wild-in-tunisia-chemical-variability-and-antifungal-activity-against-biscogniauxia-mediterranea-the-causative-agent-of-charcoal-canker
#8
Islem Yangui, Meriem Zouaoui Boutiti, Mohamed Boussaid, Chokri Messaoud
The chemical composition of five Eucalyptus species and five Myrtus communis L. populations was investigated using GC-MS and GC-FID. For Eucalyptus essential oils, 32 compounds, representing 88.56-96.83% of the total oil according to species, were identified. The main compounds were 1,8-cineole, α-pinene, p-cymene, ɤ-gurjunene, α-aromadendrene and β-phellandrene. For Myrtle essential oils, 26 compounds, representing 93.13-98.91% of the total oil were identified. α-pinene, 1,8-cineole, linalool and myrtenyl acetate were found to be the major compounds...
March 16, 2017: Chemistry & Biodiversity
https://www.readbyqxmd.com/read/28296668/contact-burns-from-shisha-charcoal-a-warning
#9
Jeremy A Maarschalk, Fergal Marlborough, Waseem Bhat
No abstract text is available yet for this article.
March 6, 2017: Journal of Burn Care & Research: Official Publication of the American Burn Association
https://www.readbyqxmd.com/read/28290084/briquettes-production-for-use-as-power-source-for-combustion-using-charcoal-thin-waste-and-sanitary-sewage-sludge
#10
Ricardo Sonsim de Oliveira, Soraya Moreno Palácio, Edson Antonio da Silva, Filipe Quadros Mariani, Thiago Olinek Reinehr
This study evaluated the feasibility of production of briquettes using fine charcoal, sewage sludge, and mixtures thereof for use in energy production. The briquettes of 7-8 cm diameter and 20 cm length were produced in the conical press extruder type, mixing sewage sludge to charcoal fines in different ratios: 0:100, 25:75, 50:50, 75:25, and 100:0, with the addition of a binder (glue flour) in a ratio of 8 mass% prepared for briquetting. After air drying (temperatures between 24 and 30°C) for 48 h, the mechanical, thermal, and morphological characterizations were performed...
March 13, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28289606/simple-efficient-and-economical-methods-for-isolation-and-estimation-of-novel-isoflavone-using-rp-hplc
#11
Afroze Alam, Kamlesh Kumar Naik, Navneet Kumar Upadhaya, Shailendra Kumar, K L Dhar
The study was undertaken to develop a simplified procedure for the isolation of bioactive isoflavone from Iris kashmiriana, using a direct method of isolation, avoiding the use of chromatographic techniques. The compound was isolated by commercially viable procedure. The extraction of powdered drug (500 g) was done with petroleum ether (60-80) using a Soxhlet apparatus (24 h run). The petroleum ether extract (gums and resins 2.13 g) was obtained and the marc (400 g) was subjected to extraction with 95% methanol using a Soxhlet apparatus (24 h run)...
2017: MethodsX
https://www.readbyqxmd.com/read/28288359/efficacy-of-wood-charcoal-and-its-modified-form-as-packing-media-for-biofiltration-of-isoprene
#12
Navnita Srivastva, Ram S Singh, Suresh K Dubey
The efficacy of wood charcoal (WC) and nutrient-enriched wood charcoal (NWC) as biofilter packing media were assessed for isoprene biodegradation in a bioreactor comprising bioscrubber and a biofilter connected in series and inoculated with Pseudomonas sp. The bioreactors using WC and NWC exhibited >90% removal efficiency and around 369 g m(-3) h(-1) elimination capacity at around 404 g m(-3) h(-1) inlet loading rate. In both the bioreactors, the biofilter component showed better degradation capacity compared to the bioscrubber unit...
March 10, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28285621/antidiarrheal-activity-of-hexane-extract-of-citrus-limon-peel-in-an-experimental-animal-model
#13
Olasupo Stephen Adeniyi, James Omale, Samuel Chukwuma Omeje, Victoria Ojimaojo Edino
OBJECTIVE: Acute diarrhea is one of the major illnesses that cause death in children, despite clinical interventions and the use of oral rehydration therapy. Thus, there is need to discover other effective, affordable and accessible treatments for this disease. Therefore, this study was carried out to investigate the effects of hexane extract of Citrus limon peel (HECLP) on castor oil-induced diarrhea in rats. METHODS: Diarrhea was induced in male albino Wistar rats weighing 100-150 g...
March 2017: Journal of Integrative Medicine
https://www.readbyqxmd.com/read/28284446/biofiltration-of-xylene-using-wood-charcoal-as-the-biofilter-media-under-transient-and-high-loading-conditions
#14
Kiran Singh, B S Giri, Amrita Sahi, S R Geed, M K Kureel, Sanjay Singh, S K Dubey, B N Rai, Surendra Kumar, S N Upadhyay, R S Singh
The main objective of this study was to evaluate the performance of wood charcoal as biofilter media under transient and high loading condition. Biofiltration of xylene was investigated for 150days in a laboratory scale unit packed with wood charcoal and inoculated with mixed microbial culture at the xylene loading rates ranged from 12 to 553gm(-3)h(-1). The kinetic analysis of the xylene revealed absence of substrate inhibition and possibility of achieving higher elimination under optimum condition. The pH, temperature, pressure drop and CO2 production rate were regularly monitored during the experiments...
February 21, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28283293/linking-energy-sanitation-agriculture-intersectional-resource-management-in-smallholder-households-in-tanzania
#15
Ariane Krause, Vera Susanne Rotter
In order to create sustainable systems for resource management, residues from cooking and ecological sanitation (EcoSan) can be employed in recycling-driven soil fertility management. However, the link between energy, sanitation, and agricultural productivity is often neglected. Hence, the potential self-sufficient nature of many smallholdings in sub-Saharan Africa is underexploited. OBJECTIVE: To compare those cooking and sanitation technologies most commonly used in north-western Tanzania with locally developed alternatives, with respect to (i) resource consumption, (ii) potential to recover resources, and (iii) environmental emissions...
March 7, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28282225/quantitative-microbial-risk-assessment-for-campylobacter-foodborne-illness-in-raw-beef-offal-consumption-in-south-korea
#16
Jiyeon Jeong, Jeeyeon Lee, Heeyoung Lee, Soomin Lee, Sejeong Kim, Jimyeong Ha, Ki-Sun Yoon, Yohan Yoon
This study evaluated the risk of Campylobacter foodborne illness caused by the intake of raw beef offal in South Korea. The prevalence of Campylobacter spp. in raw beef offal (liver and tripe) was investigated by plating samples on modified charcoal-cefoperazone-deoxycholate agar with Preston enrichment broth. Data were collected about storage temperature and length of storage of raw beef offal, and probabilistic distributions for the data were determined, using @RISK software. Predictive models were developed to describe the fate of Campylobacter in raw beef offal, and the amount and frequency of consumption and dose-response model were surveyed...
March 10, 2017: Journal of Food Protection
https://www.readbyqxmd.com/read/28278777/improvement-of-start-up-and-nitrogen-removal-of-the-anammox-process-in-reactors-inoculated-with-conventional-activated-sludge-using-biofilm-carrier-materials
#17
Yi-Feng Lu, Li-Juan Ma, Lan Ma, Bei Shan, Jun-Jun Chang
The start-up of the anaerobic ammonium oxidation (anammox) process in three up-flow column reactors seeded with common mixed activated sludge and added with three materials, sponge (R1), sponge + volcanic rock (R2) and sponge + charcoal (R3), as carriers for biofilm formation were comparatively investigated in this study. The supplement of volcanic rock and charcoal could significantly shorten the start-up time of the anammox process, which primarily occurred in the activity-enhanced phase, with ammonium and nitrite removal efficiencies stabilized above 92...
February 28, 2017: Environmental Technology
https://www.readbyqxmd.com/read/28278090/enhancing-faecal-sludge-dewaterability-and-end-use-by-conditioning-with-sawdust-and-charcoal-dust
#18
Swaib Semiyaga, Mackay A E Okure, Charles B Niwagaba, Philip M Nyenje, Frank Kansiime
Faecal sludge (FS) treatment in urban slums of low-income countries of sub-Saharan Africa is poor or non-existent. FS contains over 90% water and therefore, dewatering it within slums decreases transport costs, facilitates local treatment and end-use. This study was designed to enhance the dewatering efficiency of FS, using two locally available physical conditioners (sawdust and charcoal dust), each applied at dosages of 0, 25, 50, 75, 100 and 125% TS. The optimum dosage for both conditioners occurred at 50 and 75% for cake moisture content and capillary suction time, respectively...
March 1, 2017: Environmental Technology
https://www.readbyqxmd.com/read/28264206/chamomile-flower-myrrh-and-coffee-charcoal-components-of-a-traditional-herbal-medicinal-product-diminish-proinflammatory-activation-in-human-macrophages
#19
Cica Vissiennon, Dima Hammoud, Steffen Rodewald, Karin Fester, Karl-Heinz Goos, Karen Nieber, Jürgen Arnhold
A traditional herbal medicinal product, containing myrrh, chamomile flower, and coffee charcoal, has been used in Germany for the relief of gastrointestinal complaints for decades. Clinical studies suggest its use in the maintenance therapy of inflammatory bowel disease. However, the pharmacological mechanisms underlying the clinical effects are not yet fully understood.The present study aims to elucidate immunopharmacological activities of myrrh, chamomile flower, and coffee charcoal by studying the influence of each plant extract on gene expression and protein release of activated human macrophages...
March 6, 2017: Planta Medica
https://www.readbyqxmd.com/read/28263014/human-disturbance-amplifies-amazonian-el-ni%C3%A3-o-southern-oscillation-signal
#20
Mark B Bush, Alexander Correa-Metrio, Robert van Woesik, Courtney R Shadik, Crystal N H McMichael
The long-term interaction between human activity and climate is subject to increasing scrutiny. Humans homogenize landscapes through deforestation, agriculture, and burning and thereby might reduce the capacity of landscapes to provide archives of climate change. Alternatively, land-use change might overwhelm natural buffering and amplify latent climate signals, rendering them detectable. Here we examine a sub-annually resolved sedimentary record from Lake Sauce in the western Amazonian lowlands that spans 6900 years...
March 6, 2017: Global Change Biology
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