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Neurosurgical planning

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https://www.readbyqxmd.com/read/28712994/recognition-of-white-matter-bundles-using-local-and-global-streamline-based-registration-and-clustering
#1
REVIEW
Eleftherios Garyfallidis, Marc-Alexandre Côté, Francois Rheault, Jasmeen Sidhu, Janice Hau, Laurent Petit, David Fortin, Stephen Cunanne, Maxime Descoteaux
Virtual dissection of diffusion MRI tractograms is cumbersome and needs extensive knowledge of white matter anatomy. This virtual dissection often requires several inclusion and exclusion regions-of-interest that make it a process that is very hard to reproduce across experts. Having automated tools that can extract white matter bundles for tract-based studies of large numbers of people is of great interest for neuroscience and neurosurgical planning. The purpose of our proposed method, named RecoBundles, is to segment white matter bundles and make virtual dissection easier to perform...
July 13, 2017: NeuroImage
https://www.readbyqxmd.com/read/28686124/influence-of-an-intratumoral-cyst-on-drug-distribution-by-convection-enhanced-delivery-case-report
#2
Iryna Ivasyk, Peter F Morgenstern, Eva Wembacher-Schroeder, Mark M Souweidane
Convection-enhanced delivery (CED) uses positive pressure to induce convective flow of molecules and maximize drug distribution. Concerns have been raised about the effect of cystic structures on uniform drug distribution with CED. The authors describe the case of a patient with a diffuse intrinsic pontine glioma (DIPG) with a large cyst and examine its effect on drug distribution after CED with a radiolabeled antibody. The patient was treated according to protocol with CED of (124)I-8H9 to the pons for nonprogressive DIPG after radiation therapy as part of a Phase I trial (clinical trial registration no...
July 7, 2017: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/28684152/access-disparities-to-magnet-hospitals-for-patients-undergoing-neurosurgical-operations
#3
REVIEW
Symeon Missios, Kimon Bekelis
BACKGROUND: Centers of excellence focusing on quality improvement have demonstrated superior outcomes for a variety of surgical interventions. We investigated the presence of access disparities to hospitals recognized by the Magnet Recognition Program of the American Nurses Credentialing Center (ANCC) for patients undergoing neurosurgical operations. METHODS: We performed a cohort study of all neurosurgery patients who were registered in the New York Statewide Planning and Research Cooperative System (SPARCS) database from 2009 to 2013...
July 3, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28677108/design-fluency-and-neuroanatomical-correlates-in-54-neurosurgical-patients-with-lesions-to-the-right-hemisphere
#4
Dario Marin, Eleonora Madotto, Franco Fabbro, Miran Skrap, Barbara Tomasino
We addressed the neuroanatomical correlates of 54 right-brain-damaged neurosurgical patients on visuo-spatial design fluency, which is a measure of the ability to generate/plan a series of new abstract combinations in a flexible way. 22.2% of the patients were impaired. They failed the task because they did not use strategic behavior, in particular they used rotational strategy to a significantly lower extent and produced a significantly higher rate of perseverative errors. Overall performance did not correlate with neuropsychological tests, suggesting that proficient performance was independent of other cognitive domains...
July 4, 2017: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/28665384/-the-phenomenon-of-long-term-survival-in-glioblastoma-patients-part-i-the-role-of-clinical-and-demographic-factors-and-an-idh1-mutation-r-132-h
#5
S A Goryaynov, M F Gol'dberg, A V Golanov, S V Zolotova, L V Shishkina, M V Ryzhova, D I Pitskhelauri, V Yu Zhukov, D Yu Usachev, A Yu Belyaev, A V Kondrashov, V A Shurkhay, A A Potapov
The median overall survival of glioblastoma patients is about 15 months. Only a small number of patients survive 3 years. The factors of a favorable prognosis for the 'longevity phenomenon' in glioblastoma patients are not fully understood. OBJECTIVE: to determine the occurrence rate of long-living patients with glioblastomas, identify clinical predictors of a favorable prognosis, and identify the presence and prognostic significance of an IDH1 mutation. MATERIAL AND METHODS: Among 1494 patients operated on for glioblastoma at the Burdenko Neurosurgical Institute from 2007 to 2012, there were 84 (5...
2017: Zhurnal Voprosy Neĭrokhirurgii Imeni N. N. Burdenko
https://www.readbyqxmd.com/read/28664037/white-matter-tractography-for-neurosurgical-planning-a-topography-based-review-of-the-current-state-of-the-art
#6
REVIEW
Walid I Essayed, Fan Zhang, Prashin Unadkat, G Rees Cosgrove, Alexandra J Golby, Lauren J O'Donnell
We perform a review of the literature in the field of white matter tractography for neurosurgical planning, focusing on those works where tractography was correlated with clinical information such as patient outcome, clinical functional testing, or electro-cortical stimulation. We organize the review by anatomical location in the brain and by surgical procedure, including both supratentorial and infratentorial pathologies, and excluding spinal cord applications. Where possible, we discuss implications of tractography for clinical care, as well as clinically relevant technical considerations regarding the tractography methods...
2017: NeuroImage: Clinical
https://www.readbyqxmd.com/read/28637947/neurosurgical-virtual-reality-simulation-for-brain-tumor-using-high-definition-computer-graphics-a-review-of-the-literature
#7
Taichi Kin, Hirofumi Nakatomi, Naoyuki Shono, Seiji Nomura, Toki Saito, Hiroshi Oyama, Nobuhito Saito
Simulation and planning of surgery using a virtual reality model is becoming common with advances in computer technology. In this study, we conducted a literature search to find trends in virtual simulation of surgery for brain tumors. A MEDLINE search for "neurosurgery AND (simulation OR virtual reality)" retrieved a total of 1,298 articles published in the past 10 years. After eliminating studies designed solely for education and training purposes, 28 articles about the clinical application remained. The finding that the vast majority of the articles were about education and training rather than clinical applications suggests that several issues need be addressed for clinical application of surgical simulation...
June 22, 2017: Neurologia Medico-chirurgica
https://www.readbyqxmd.com/read/28605532/pet-imaging-in-patients-with-meningioma-report-of-the-rano-pet-group
#8
Norbert Galldiks, Nathalie L Albert, Michael Sommerauer, Anca L Grosu, Ute Ganswindt, Ian Law, Matthias Preusser, Emilie Le Rhun, Michael A Vogelbaum, Gelareh Zadeh, Frédéric Dhermain, Michael Weller, Karl-Josef Langen, Jörg C Tonn
Meningiomas are the most frequent non-glial primary brain tumors and represent about 30% of brain tumors. Usually, diagnosis and treatment planning are based on neuroimaging using mainly magnetic resonance imaging (MRI) or rarely computed tomography (CT). Most common treatment options are neurosurgical resection and radiotherapy, e.g., radiosurgery or external fractionated radiotherapy. For follow-up after treatment, structural imaging techniques such as MRI or CT are used. However, these structural imaging modalities have limitations, particularly in terms of tumor delineation as well as diagnosis of posttherapeutic reactive changes...
June 12, 2017: Neuro-oncology
https://www.readbyqxmd.com/read/28544168/presurgical-language-fmri-mapping-of-six-critical-regions
#9
Christopher F Benjamin, Patricia D Walshaw, Kayleigh Hale, William D Gaillard, Leslie C Baxter, Madison M Berl, Monika Polczynska, Stephanie Noble, Rafeed Alkawadri, Lawrence J Hirsch, R Todd Constable, Susan Y Bookheimer
Language mapping is a key goal in neurosurgical planning. fMRI mapping typically proceeds with a focus on Broca's and Wernicke's areas, although multiple other language-critical areas are now well-known. We evaluated whether clinicians could use a novel approach, including clinician-driven individualized thresholding, to reliably identify six language regions, including Broca's Area, Wernicke's Area (inferior, superior), Exner's Area, Supplementary Speech Area, Angular Gyrus, and Basal Temporal Language Area...
August 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/28540820/theoretical-model-for-laser-ablation-outcome-predictions-in-brain-calibration-and-validation-on-clinical-mr-thermometry-images
#10
Samuel John Fahrenholtz, Reza Madankan, Shabbar Danish, John D Hazle, R Jason Stafford, David Fuentes
PURPOSE: Neurosurgical laser ablation is experiencing a renaissance. Computational tools for ablation planning aim to further improve the intervention. Here, global optimisation and inverse problems are demonstrated to train a model that predicts maximum laser ablation extent. METHODS: A closed-form steady state model is trained on and then subsequently compared to N = 20 retrospective clinical MR thermometry datasets. Dice similarity coefficient (DSC) is calculated to provide a measure of region overlap between the 57 °C isotherms of the thermometry data and the model-predicted ablation regions; 57 °C is a tissue death surrogate at thermal steady state...
May 19, 2017: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/28538516/left-lateralization-of-resting-state-functional-connectivity-between-the-presupplementary-motor-area-and-primary-language-areas
#11
William Lou, Kyung K Peck, Nicole Brennan, Arka Mallela, Andrei Holodny
An abundance of evidence points to the role of a presupplementary motor area (pre-SMA) in human language. This study explores the pre-SMA resting state connectivity network and the nature of its connections to known language areas. We tested the hypothesis that by seeding the pre-SMA, one would be able to establish language laterality to known cortical and subcortical language areas. We analyzed data from 30 right-handed healthy controls and performed the resting state functional MRI. A seed-based analysis using a manually drawn pre-SMA region of interest template was applied...
July 5, 2017: Neuroreport
https://www.readbyqxmd.com/read/28529875/advanced-magnetic-resonance-imaging-and-neuropsychological-assessment-for-detecting-brain-injury-in-a-prospective-cohort-of-university-amateur-boxers
#12
M G Hart, C R Housden, J Suckling, R Tait, A Young, U Müller, V F J Newcombe, I Jalloh, B Pearson, J Cross, R A Trivedi, J D Pickard, B J Sahakian, P J Hutchinson
BACKGROUND/AIM: The safety of amateur and professional boxing is a contentious issue. We hypothesised that advanced magnetic resonance imaging and neuropsychological testing could provide evidence of acute and early brain injury in amateur boxers. METHODS: We recruited 30 participants from a university amateur boxing club in a prospective cohort study. Magnetic resonance imaging (MRI) and neuropsychological testing was performed at three time points: prior to starting training; within 48 h following a first major competition to detect acute brain injury; and one year follow-up...
2017: NeuroImage: Clinical
https://www.readbyqxmd.com/read/28481397/endoscopic-endonasal-cerebrospinal-fluid-leak-repair-on-the-ventral-midline-skull-base-a-single-neurosurgical-center-experience
#13
Cihan Isler, Merdin Lyutviev Ahmedov, Mehmet Yigit Akgun, Baris Kucukyuruk, Nurperi Gazioglu, Galip Sanus, Necmettin Tanriover
AIM: The aim of this study was to present the results of endoscopic endonasal repair of ventral midline skull base cerebrospinal fluid (CSF) leak (VMSBL) at our institution and to discuss the technique and results from a neurosurgical perspective. MATERIAL AND METHODS: A retrospective analysis of all VMSBL cases that underwent endoscopic endonasal skull base approach (EESBA) for CSF leak repair at a single tertiary neurosurgical center was performed. Twenty six patients with an average age of 44...
March 25, 2017: Turkish Neurosurgery
https://www.readbyqxmd.com/read/28472336/association-of-hospitalization-for-neurosurgical-operations-in-magnet-hospitals-with-mortality-and-length-of-stay
#14
Symeon Missios, Kimon Bekelis
BACKGROUND: The association of Magnet hospital status with improved surgical outcomes remains an issue of debate. OBJECTIVE: To investigate whether hospitalization in a Magnet hospital is associated with improved outcomes for patients undergoing neurosurgical operations. METHODS: A cohort study was executed using all patients undergoing neurosurgical operations in New York registered in the Statewide Planning and Research Cooperative System database from 2009 to 2013...
May 3, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28463617/robot-assisted-procedures-in-pediatric-neurosurgery
#15
Alessandro De Benedictis, Andrea Trezza, Andrea Carai, Elisabetta Genovese, Emidio Procaccini, Raffaella Messina, Franco Randi, Silvia Cossu, Giacomo Esposito, Paolo Palma, Paolina Amante, Michele Rizzi, Carlo Efisio Marras
OBJECTIVE During the last 3 decades, robotic technology has rapidly spread across several surgical fields due to the continuous evolution of its versatility, stability, dexterity, and haptic properties. Neurosurgery pioneered the development of robotics, with the aim of improving the quality of several procedures requiring a high degree of accuracy and safety. Moreover, robot-guided approaches are of special interest in pediatric patients, who often have altered anatomy and challenging relationships between the diseased and eloquent structures...
May 2017: Neurosurgical Focus
https://www.readbyqxmd.com/read/28463609/initial-academic-experience-and-learning-curve-with-robotic-spine-instrumentation
#16
Timur M Urakov, Ken Hsuan-Kan Chang, S Shelby Burks, Michael Y Wang
OBJECTIVE Spine surgery is complex and involves various steps. Current robotic technology is mostly aimed at assisting with pedicle screw insertion. This report evaluates the feasibility of robot-assisted pedicle instrumentation in an academic environment with the involvement of residents and fellows. METHODS The Renaissance Guidance System was used to plan and execute pedicle screw placement in open and percutaneous consecutive cases performed in the period of December 2015 to December 2016. The database was reviewed to assess the usability of the robot by neurosurgical trainees...
May 2017: Neurosurgical Focus
https://www.readbyqxmd.com/read/28458878/rendering-a-ruptured-arteriovenous-malformation-more-susceptible-to-spontaneous-obliteration-as-a-possible-treatment-strategy-for-cerebral-avm
#17
Szu-Kai Hsu, Chih-Ju Chang, I-Chang Su
Spontaneous regression of cerebral arteriovenous malformation (AVM) is a rare phenomenon, but its occurrence is an important consideration in treatment planning. A 58-year-old male was found to have a high-flow AVM of Spetzler-Martin Grade III. Before his scheduled treatment, the AVM ruptured with a large parenchymal hemorrhage. Following emergency decompressive surgery, a targeted embolization procedure was performed to obliterate the ruptured weak point and to reduce the shunting flow. The residual AVM became a malformation harboring angio-architectural factors favoring spontaneous obliteration...
April 2017: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/28456743/does-objective-quality-of-physicians-correlate-with-patient-satisfaction-measured-by-hospital-compare-metrics-in-new-york-state
#18
Kimon Bekelis, Symeon Missios, Todd A MacKenzie, Patrick M O'Shaughnessy
BACKGROUND: It is unclear whether publicly reported benchmarks correlate with quality of physicians and institutions. We investigated the association of patient satisfaction measures from a public reporting platform with performance of neurosurgeons in New York State. METHODS: This cohort study comprised patients undergoing neurosurgical operations from 2009 to 2013 who were registered in the Statewide Planning and Research Cooperative System database. The cohort was merged with publicly available data from the Centers for Medicare and Medicaid Services Hospital Compare website...
July 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28414967/pharmacodynamics-of-remifentanil-induced-intracranial-spike-activity-in-mesial-temporal-lobe-epilepsy
#19
Troels Wesenberg Kjaer, Hans Hogenhaven, Andrea P Lee, Flemming Find Madsen, Bo Jespersen, Jannick Brennum, Lennart Derm, Finn Borgbjerg Moltke
Patients with medically refractory epilepsy may benefit from resective epilepsy surgery. However even the best centers experience surgical failures. It is therefore important to find techniques that may aid in neurosurgical planning of epileptic focus resection. Recordings of electrical brain activity with EEG during seizures reveal abnormal cortical hypersynchronization. Between seizures the EEG often shows interictal depolarizing phenomena such as spikes reflecting an irritable focus of the brain. In the present study we investigated the effect of intravenous remifentanil on the spike activity in the temporal neocortex and hippocampus...
March 31, 2017: Epilepsy Research
https://www.readbyqxmd.com/read/28400898/many-neurology-readmissions-are-nonpreventable
#20
Sidney T Le, S Andrew Josephson, Hans A Puttgen, Lorrie Gibson, Elan L Guterman, Heather M Leicester, Carla L Graf, John C Probasco
INTRODUCTION: Reducing unplanned hospital readmissions has become a national focus due to the Centers for Medicare and Medicaid Services' (CMS) penalties for hospitals with high rates. A first step in reducing unplanned readmission is to understand which patients are at high risk for readmission, which readmissions are planned, and how well planned readmissions are currently captured in comparison to patient-level chart review. METHODS: We examined all 5455 inpatient neurology admissions over a 2-year period to University of California San Francisco Medical Center and Johns Hopkins Hospital via chart review...
April 2017: Neurohospitalist
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