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https://www.readbyqxmd.com/read/28212096/system-level-design-of-a-64-channel-low-power-neural-spike-recording-sensor
#1
Manuel Delgado-Restituto, Alberto Rodriguez-Perez, Angela Darie, Cristina Soto-Sanchez, Eduardo Fernandez-Jover, Angel Rodriguez-Vazquez
This paper reports an integrated 64-channel neural spike recording sensor, together with all the circuitry to process and configure the channels, process the neural data, transmit via a wireless link the information and receive the required instructions. Neural signals are acquired, filtered, digitized and compressed in the channels. Additionally, each channel implements an auto-calibration algorithm which individually configures the transfer characteristics of the recording site. The system has two transmission modes; in one case the information captured by the channels is sent as uncompressed raw data; in the other, feature vectors extracted from the detected neural spikes are released...
February 13, 2017: IEEE Transactions on Biomedical Circuits and Systems
https://www.readbyqxmd.com/read/28210394/efficacy-and-safety-of-a-novel-100-silicone-scar-gel-treatment-for-early-intervention-in-scar-management
#2
David J Goldberg
Objective: To evaluate the efficacy and safety of a new topical silicone gel for the early intervention in the management of scars. Design: In this 12-week, observational study, healthy subjects (n=15) with an accessible linear or hypertrophic scar were given the test product and instructed to apply twice daily. Subjects returned 14, 28, 56, and 84 days later for evaluation and recording of adverse events. Setting: Private practice of the author. Participants: Eligible subjects had a scar with a Vancouver Scar Scale total score ≥3 at baseline...
December 2016: Journal of Clinical and Aesthetic Dermatology
https://www.readbyqxmd.com/read/28209318/an-evaluation-of-physical-activity-training-in-australian-medical-school-curricula
#3
Abigail Strong, Mark Stoutenberg, Anita Hobson-Powell, Mark Hargreaves, Halle Beeler, Emmanuel Stamatakis
OBJECTIVES: To evaluate the current level of physical activity (PA) training provided to Australian medical students. DESIGN: Individual interviews were completed via phone interview or online survey from June-October 2015. METHODS: Program leaders from Australian medical schools, who were knowledgeable about their curriculum content, were invited to participate in the study. The number of programs, hours of PA training instruction, institutional attitude towards offering PA, barriers experienced, and content areas in which PA training was offered, were explored...
October 28, 2016: Journal of Science and Medicine in Sport
https://www.readbyqxmd.com/read/28209215/the-relevance-of-goal-orientation-for-motivation-in-high-versus-low-proneness-to-negative-symptoms
#4
Björn Schlier, Maike Engel, Anne-Katharina Fladung, Anja Fritzsche, Tania M Lincoln
BACKGROUND: The psychological mechanisms of why individuals with negative symptoms fail to initiate and perform goal-directed behavior are not well understood. Drawing on the reward-sensitivity and expectancy-value theories, we investigate whether negative symptom-like experiences (NSLE) are associated with generating less approach goals (aimed at reaching a positive outcome) and more avoidance goals (aimed at avoiding a negative outcome) and whether this type of goal-orientation explains motivational deficits (i...
June 2017: Journal of Behavior Therapy and Experimental Psychiatry
https://www.readbyqxmd.com/read/28206679/technical-note-determination-of-individual-thyroid-clearance-effective-half-life-with-a-common-handheld-electronic-dosimeter
#5
Markus Fürstner, Michael Hentschel, Petar-Marko Spanjol, George A Prenosil, Sabine Weidner, Thomas Krause, Bernd Klaeser
PURPOSE: To determine the thyroid clearance effective half-life (Ʈ) with a common handheld electronic dosimeter (ED) in patients undergoing radioiodine treatment for hyperthyroidism. METHODS: Dose rates from twelve inpatients were measured daily with an ED and with a clinical uptake counter. The ED was attached to the patient with two different setups, one using a cervical collar and another employing a neck strap. Estimation of Ʈ was performed by linear regression analysis of the log of both the ED and the uptake counter measurements versus time...
February 16, 2017: Medical Physics
https://www.readbyqxmd.com/read/28204933/a-systematic-review-of-patient-reported-outcome-measures-following-transsexual-surgery
#6
REVIEW
M Barone, A Cogliandro, N Di Stefano, V Tambone, P Persichetti
BACKGROUND: The aims of our study were to identify studies that evaluated patient satisfaction after transsexual surgery, analyze existing questionnaires, and summarize their development, psychometric properties, and content. METHODS: A systematic review of the English-language literature was performed. Patient-reported outcome measures designed to assess patient satisfaction and quality of life following transsexual surgery were identified. Qualifying instruments were assessed for content and adherence to international guidelines for development and validation...
February 15, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28196139/using-data-from-the-microsoft-kinect-2-to-determine-postural-stability-in-healthy-subjects-a-feasibility-trial
#7
Behdad Dehbandi, Alexandre Barachant, Anna H Smeragliuolo, John Davis Long, Silverio Joseph Bumanlag, Victor He, Anna Lampe, David Putrino
The objective of this study was to determine whether kinematic data collected by the Microsoft Kinect 2 (MK2) could be used to quantify postural stability in healthy subjects. Twelve subjects were recruited for the project, and were instructed to perform a sequence of simple postural stability tasks. The movement sequence was performed as subjects were seated on top of a force platform, and the MK2 was positioned in front of them. This sequence of tasks was performed by each subject under three different postural conditions: "both feet on the ground" (1), "One foot off the ground" (2), and "both feet off the ground" (3)...
2017: PloS One
https://www.readbyqxmd.com/read/28194135/inaccurate-saccades-and-enhanced-vestibulo-ocular-reflex-suppression-during-combined-eye-head-movements-in-patients-with-chronic-neck-pain-possible-implications-for-cervical-vertigo
#8
Janine L Johnston, Pierre M Daye, Glen T D Thomson
BACKGROUND: The primate ocular motor system is designed to acquire peripheral targets of interest by coordinating visual, vestibular, and neck muscle activation signals. The vestibulo-ocular reflex (VOR) is greatly reduced at the onset of large eye-head (gaze) saccades and resumes before the end of the saccades to stabilize eye-in-orbit and ensure accurate target acquisition. Previous studies have relied on manipulating head movements in normal individuals to study VOR suppression and gaze kinematics...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28193793/guidance-on-completing-a-written-allergy-and-anaphylaxis-emergency-plan
#9
Julie Wang, Scott H Sicherer
Anaphylaxis is a potentially life-threatening, severe allergic reaction. The immediate assessment of patients having an allergic reaction and prompt administration of epinephrine, if criteria for anaphylaxis are met, promote optimal outcomes. National and international guidelines for the management of anaphylaxis, including those for management of allergic reactions at school, as well as several clinical reports from the American Academy of Pediatrics, recommend the provision of written emergency action plans to those at risk of anaphylaxis, in addition to the prescription of epinephrine autoinjectors...
February 13, 2017: Pediatrics
https://www.readbyqxmd.com/read/28193490/physical-activity-and-academic-achievement-across-the-curriculum-results-from-a-3-year-cluster-randomized-trial
#10
Joseph E Donnelly, Charles H Hillman, Jerry L Greene, David M Hansen, Cheryl A Gibson, Debra K Sullivan, John Poggio, Matthew S Mayo, Kate Lambourne, Amanda N Szabo-Reed, Stephen D Herrmann, Jeffery J Honas, Mark R Scudder, Jessica L Betts, Katherine Henley, Suzanne L Hunt, Richard A Washburn
We compared changes in academic achievement across 3years between children in elementary schools receiving the Academic Achievement and Physical Activity Across the Curriculum intervention (A+PAAC), in which classroom teachers were trained to deliver academic lessons using moderate-to-vigorous physical activity (MVPA) compared to a non-intervention control. Elementary schools in eastern Kansas (n=17) were cluster randomized to A+PAAC (N=9, target ≥100min/week) or control (N=8). Academic achievement (math, reading, spelling) was assessed using the Wechsler Individual Achievement Test-Third Edition (WIAT-III) in a sample of children (A+PAAC=316, Control=268) in grades 2 and 3 at baseline (Fall 2011) and repeated each spring across 3years...
February 10, 2017: Preventive Medicine
https://www.readbyqxmd.com/read/28191988/mock-juror-evaluations-of-traditional-and-ratings-based-eyewitness-identification-evidence
#11
James D Sauer, Matthew A Palmer, Neil Brewer
Compared to categorical identifications, culprit likelihood ratings (having the witness rate, for each lineup member, the likelihood that the individual is the culprit) provide a promising alternative for assessing a suspect's likely guilt. Four experiments addressed 2 broad questions about the use of culprit likelihood ratings evidence by mock-jurors. First, are mock-jurors receptive to noncategorical forms of identification evidence? Second, does the additional information provided by ratings (relating to discrimination) affect jurors' evaluations of the identification evidence? Experiments 1 and 1A manipulated confidence (90% vs...
February 13, 2017: Law and Human Behavior
https://www.readbyqxmd.com/read/28188717/-measurement-in-epidemiology-prevalence-incidence-risk-impact-measures
#12
Arturo Fajardo-Gutiérrez
Measurement is essential in epidemiology, and this is why detailed knowledge of the different measures that are estimated in this discipline is necessary, since information interpretation and, most importantly, the decisions made in the care of patients depend on it. This article describes the three main groups of measures in epidemiology: frequency, association and potential impact; examples and instructions for their calculation are also provided. Incidence and prevalence are the most significant frequency measures, and can be obtained when both morbidity and mortality of diseases are studied...
January 2017: Revista Alergia Mexico: Organo Oficial de la Sociedad Mexicana de Alergia e Inmunología, A.C
https://www.readbyqxmd.com/read/28183413/manuscript-development-and-publishing-a-5-step-approach
#13
Susan M Downey, Stephen A Geraci
Publications in peer-reviewed biomedical journals are essential for sharing knowledge and advancing healthcare. This article will articulate a 5-step approach for developing and publishing a manuscript, and provide academic clinicians with an instructional tool they can provide to their protégés and junior faculty. The authors attempt to distill existing advice for preparing manuscripts, which is found in myriad formats, combine these tutorials with their collective experience and present this approach for developing and publishing successfully a manuscript in a peer-reviewed journal...
February 2017: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/28183408/developing-a-physician-s-professional-identity-through-medical-education
#14
Kenneth E Olive, Caroline L Abercrombie
Professionalism represents a fundamental characteristic of physicians. Professional organizations have developed professionalism competencies for physicians and medical students. The aim of teaching medical professionalism is to ensure the development of a professional identity in medical students. Professional identity formation is a process developed through teaching principles and appropriate behavioral responses to the stresses of being a physician. Addressing lapses and critical reflection is an important part of the educational process...
February 2017: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/28182459/deconstructing-the-simplification-of-jury-instructions-how-simplifying-the-features-of-complexity-affects-jurors-application-of-instructions
#15
Chantelle M Baguley, Blake M McKimmie, Barbara M Masser
Research consistently shows that techniques currently used to simplify jury instructions do not always improve mock jurors' comprehension. If improvements are observed, these are limited and overall comprehension remains low. It is unclear, however, why this occurs. It is possible that current simplification techniques do not effectively simplify the features of complexity, present in standardized instructions, which have the greatest effect on jurors' comprehension. It is not yet known, however, how much each feature of complexity individually affects jurors' comprehension...
February 9, 2017: Law and Human Behavior
https://www.readbyqxmd.com/read/28182018/genome-wide-base-resolution-mapping-of-dna-methylation-in-single-cells-using-single-cell-bisulfite-sequencing-scbs-seq
#16
Stephen J Clark, Sébastien A Smallwood, Heather J Lee, Felix Krueger, Wolf Reik, Gavin Kelsey
DNA methylation (DNAme) is an important epigenetic mark in diverse species. Our current understanding of DNAme is based on measurements from bulk cell samples, which obscures intercellular differences and prevents analyses of rare cell types. Thus, the ability to measure DNAme in single cells has the potential to make important contributions to the understanding of several key biological processes, such as embryonic development, disease progression and aging. We have recently reported a method for generating genome-wide DNAme maps from single cells, using single-cell bisulfite sequencing (scBS-seq), allowing the quantitative measurement of DNAme at up to 50% of CpG dinucleotides throughout the mouse genome...
March 2017: Nature Protocols
https://www.readbyqxmd.com/read/28181886/udl-and-intellectual-disability-what-do-we-know-and-where-do-we-go
#17
Kavita Rao, Sean J Smith, K Alisa Lowrey
As an instructional design framework that can be used to design curriculum for students with and without disabilities, Universal Design for Learning (UDL) has the potential to support meaningful inclusion of students with intellectual disability (ID) in general educational settings. This article presents an overview of the existing set of research studies on UDL application for students with ID in PreK-12 settings. The current body of research illustrates that UDL is being applied to instructional activities for students with ID to examine a variety of interventions (e...
February 2017: Intellectual and Developmental Disabilities
https://www.readbyqxmd.com/read/28178034/the-neurobiology-of-health-communication
#18
Peter A Hall, Kirk I Erickson, Peter J Gianaros
This issue of Psychosomatic Medicine describes findings from an innovative study by Kang et al. employing neuroimaging methods to quantify neural responses to health communications. Findings indicated that those sedentary individuals who hold self-transcendent values show attenuated limbic threat responses to communications about the benefits of physical activity. Furthermore, participants who were instructed to articulate such values showed some evidence of additional blunting of the same neural response. In this editorial we provide context for the interpretation of these findings within the existing research using the brain-as-predictor approach, and other recent trends within biobehavioral medicine involving the use of neuroscience methods in the service of health behavior change...
February 7, 2017: Psychosomatic Medicine
https://www.readbyqxmd.com/read/28177728/long-term-effects-of-daily-postprandial-physical-activity-on-blood-glucose-a-randomized-controlled-trial
#19
Håvard Nygaard, Eirik Grindaker, Bent Ronny Rønnestad, Gerd Holmboe-Ottesen, Arne Torbjørn Høstmark
Previous studies have shown that a bout of moderate or light postprandial physical activity effectively blunts the postprandial increase in blood glucose. The objective of this study was to test whether regular light postprandial physical activity can improve glycemia in persons with hyperglycemia or with high risk of hyperglycemia. We randomized 56 participants to an intervention or a control group. They were diagnosed as hyperglycemic, not using anti-diabetics or categorized as high-risk individuals for type 2 diabetes...
January 3, 2017: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/28167331/turning-lemonade-into-lemons-dampening-appraisals-reduce-positive-affect-and-increase-negative-affect-during-positive-activity-scheduling
#20
Leigh-Anne Burr, Mahmood Javiad, Grace Jell, Aliza Werner-Seidler, Barnaby D Dunn
The way individuals appraise positive emotions may modulate affective experience during positive activity scheduling. Individuals may either engage in dampening appraisals (e.g., think "this is too good to last") or amplifying appraisals (e.g., think "I deserve this"). A cross-over randomized design was used to examine the consequences of these appraisal styles. Participants (N = 43) rated positive affect (PA) and negative affect (NA) during four daily walks in pleasant locations, whilst following dampening, emotion-focus amplifying (focusing on how good one feels), self-focus amplifying (focusing on positive self qualities), or control instructions...
January 24, 2017: Behaviour Research and Therapy
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