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https://www.readbyqxmd.com/read/28817122/single-cell-mechanogenetics-using-monovalent-magnetoplasmonic-nanoparticles
#1
Ji-Wook Kim, Daeha Seo, Jung-Uk Lee, Kaden M Southard, Yongjun Lim, Daehyun Kim, Zev J Gartner, Young-Wook Jun, Jinwoo Cheon
Spatiotemporal interrogation of signal transduction at the single-cell level is necessary to answer a host of important biological questions. This protocol describes a nanotechnology-based single-cell and single-molecule perturbation tool, termed mechanogenetics, that enables precise spatial and mechanical control over genetically encoded cell-surface receptors in live cells. The key components of this tool are a magnetoplasmonic nanoparticle (MPN) actuator that delivers defined spatial and mechanical cues to receptors through target-specific one-to-one engagement and a micromagnetic tweezers (μMT) that remotely controls the magnitude of force exerted on a single MPN...
September 2017: Nature Protocols
https://www.readbyqxmd.com/read/28816285/-expression-of-cxcl16-cxcr6-in-fibroblast-like-synoviocytes-in-rheumatoid-arthritis-and-its-role-in-synoviocyte-proliferation
#2
X Zhang, J X Zhao, L Sun, X Y Liu
OBJECTIVE: It has been found that serum CXCL16 concentration in rheumatoid arthritis (RA) patients are significantly higher than those in osteoarthritis (OA) and normal subjects, and are positively correlated with disease activity and bone erosion. However, how is CXCL16 involved in the pathogenesis of RA is unclear. To evaluate the expression of CXCL16 and its receptor CXCR6 in fibroblast-like synoviocytes (FLS) of rheumatoid arthritis (RA) patients, and to explore the role of CXCL16 in the proliferation of RA-FLS...
August 18, 2017: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/28816196/denture-hygiene-knowledge-and-practices-among-complete-denture-wearers-attending-a-postgraduate-dental-institute
#3
Thatapudi Shankar, Snigdha Gowd, Vinay Suresan, Sneha Mantri, Sudhanshu Saxena, Prateek Mishra, Pragya Panday
AIMS: The aim of this study was to assess the denture hygiene knowledge and practices among patients using complete dentures attending a postgraduate dental hospital in Jabalpur city. The objective of this study was to assess the relationship between hygiene knowledge and practices to the denture wearer's gender, education, and income. MATERIALS AND METHODS: A descriptive, cross-sectional survey was conducted using a self-administered questionnaire involving the complete denture patients attending the Department of Prosthodontics...
August 1, 2017: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/28816195/pentraxin-3-levels-in-gingival-crevicular-fluid-during-canine-retraction-with-nickel-titanium-coil-spring-and-active-tieback
#4
Rakesh Thukral, Sukhpreet Mangat, Anvesha Ganguly, Sanket S Agarkar, Harleen Bali, Shekhar Grover
AIM: Orthodontic treatment is routinely carried out in patients with the purpose of correcting various forms of dental malocclusions. Retraction of the canines can be achieved either individually or along with incisor. Pentraxin-3 (PTX-3) is regarded as the true independent indicator of disease activity. Hence, we undertook the present study to assess and compare the level of PTX-3 in patients undergoing canine retraction with active tieback and Nickel-Titanium (NiTi) coil spring. MATERIALS AND METHODS: The present study included assessment of 25 patients that underwent canine retraction as a part of fixed orthodontic treatment...
August 1, 2017: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/28812952/impact-of-adult-attachment-anxiety-on-deception-judgments-examining-the-moderating-effect-of-motivation
#5
Song Wu, Wei Cai, Yanjun Zhang, Ying Liu, Shenghua Jin
Several psychologists have paid attention to individual differences in deception detection, but only a few studies have found significant results. The present study aimed to explore the relationship between attachment anxiety and deception judgment when there are no obvious cues to distinguish lies from truth, and to examine the moderating effect of motives. Participants were instructed to judge each of 10 audios on whether they were true or false. Subsequently, the attachment anxiety of participants was assessed using the Experiences in Close Relationships questionnaire...
January 1, 2017: Psychological Reports
https://www.readbyqxmd.com/read/28811776/role-of-ramadan-specific-diabetes-education-rsde-a-prospective-study
#6
Muhammad Yakoob Ahmedani, Shahid Ahsan, Muhammad Saif Ul Haque
OBJECTIVE: To observe the role of Ramadan Specific Diabetes Education (RSDE) in the management of fasting patients with diabetes. METHODS: This prospective study was carried out at out-patients department (OPD) of Baqai Institute of Diabetology & Endocrinology (BIDE), in 2012. Recruitment of patients started a month prior to Ramadan. Muslim patients with diabetes whether had their first or on follow up visit to the OPD and showed intention to hold fast in the month of Ramadan, were included...
May 2017: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/28807495/the-colorful-spectrum-of-tourette-syndrome-and-its-medical-surgical-and-behavioral-therapies
#7
Jan Roth
Tourette syndrome (TS) is a common neuropsychiatric disorder, more common in males than females, with onset before age 18. TS is characterized by multiple motor tics and one or more vocal/phonic tics, persisting for more than a year. Tics are unvoluntary, abrupt, rapid, repetitive, but non-rhythmic movements or sounds (vocalizations). They are preceded by an inner urge. Tics can be temporarily suppressed, but this leads to a powerful re-emergence. The performance of tics results in immediate but transient relief...
August 10, 2017: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/28805139/mental-representation-of-fractions-it-all-depends-on-whether-they-are-common-or-uncommon
#8
Fuchang Liu
This study examined whether common and uncommon fractions are mentally represented differently and whether common ones are used in accessing the magnitudes of uncommon ones. In Experiments 1 and 2, college education majors, most of whom were female, Caucasian, and in their early 20s, made comparisons involving common and uncommon fractions. In Experiment 3, participants were presented with comparison tasks involving uncommon fractions and asked to describe the strategies which they used in making such comparisons...
August 13, 2017: Quarterly Journal of Experimental Psychology: QJEP
https://www.readbyqxmd.com/read/28803724/implementation-and-outcomes-of-an-evidence-based-precepting-program-for-burn-nurses
#9
Johnnie R Robbins, Krystal K Valdez-Delgado, Nicole W Caldwell, Linda H Yoder, Elizabeth J Hayes, Michaèl G Barba, Hope L Greeley, Colleen Mitchell, Elizabeth A Mann-Salinas
INTRODUCTION: There is significant nationwide interest in transitioning new and new-to-specialty nurses into practice, especially in burn care. Lack of a structured transition program in our Burn Center was recognized as a contributing factor for nursing dissatisfaction and increased turnover compared to other hospital units. Employee evaluations exposed a need for more didactic instruction, hands-on learning, and preceptor support. The goal of this project was to implement an evidence-based transition to practice program specific to the burn specialty...
August 10, 2017: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/28793084/-use-of-medicinal-plants-as-home-remedies-in-primary-health-care-in-blumenau-state-of-santa-catarina-brazil
#10
Ana Lúcia Bertarello Zeni, Amanda Varnier Parisotto, Gerson Mattos, Ernani Tiaraju de Santa Helena
An increase in the use of alternative therapeutic practices has been observed in the past decade, especially in medicinal plants, herbal and home remedies, which has been supported by policies within the scope of the Unified Health System (SUS). This study investigated the use of home remedies by users of Primary Health Care in Blumenau, State of Santa Catarina. It is a cross-sectional, observational and epidemiological study, the data for which were obtained via a questionnaire applied to 701 individuals. An unconditional logistic regression model was used to estimate the association between the use of home remedies and socio-demographic and medical care variables...
August 2017: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/28790963/too-exhausted-to-perform-at-the-highest-level-on-the-importance-of-self-control-strength-in-educational-settings
#11
REVIEW
Chris Englert, Alafia Zavery, Alex Bertrams
In order to perform at the highest level in educational settings (e.g., students in testing situations), individuals often have to control their impulses or desires (e.g., to study for an upcoming test or to prepare a course instead of spending time with the peer group). Previous research suggests that the ability to exert self-control is an important predictor of performance and behavior in educational contexts. According to the strength model, all self-control acts are based on one global energy pool whose capacity is assumed to be limited...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28780984/reviewing-the-content-and-design-of-anaphylaxis-management-plans-published-in-english
#12
Rory D Mercer, Christina J Jones, Helen E Smith
BACKGROUND: Guidelines recommend that patients at risk of anaphylaxis are given an anaphylaxis management plan (AMP) providing advice on symptom recognition and emergency management. However, the format and content of plans is not standardized. OBJECTIVE: The objective of this study was to review the design and contents of different AMPs available in English. METHODS: A systematic internet search identified AMPs published online. Each plan was analyzed for design and content (including signs and symptoms indicative of anaphylaxis and the actions to be taken)...
August 3, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/28776677/searching-for-the-variables-that-control-human-rule-governed-insensitivity
#13
Adam E Fox, Elizabeth G E Kyonka
Verbal rules or instructions often exert obvious and meaningful control over human behavior. Sometimes instructions benefit the individual by enabling faster acquisition of a skill or by obviating an aversive consequence. However, research has also suggested a clear disadvantage: "insensitivity" to changing underlying contingencies. The two experiments described here investigated the variables that control initial rule-following behavior and rule-following insensitivity. When the initial rule was inaccurate, behavior was consistent with the rule for approximately half of participants and all participants' behavior was mostly insensitive to changing contingencies...
August 3, 2017: Journal of the Experimental Analysis of Behavior
https://www.readbyqxmd.com/read/28772188/spatial-representation-of-magnitude-in-gorillas-and-orangutans
#14
Regina Paxton Gazes, Rachel F L Diamond, Jasmine M Hope, Damien Caillaud, Tara S Stoinski, Robert R Hampton
Humans mentally represent magnitudes spatially; we respond faster to one side of space when processing small quantities and to the other side of space when processing large quantities. We determined whether spatial representation of magnitude is a fundamental feature of primate cognition by testing for such space-magnitude correspondence in gorillas and orangutans. Subjects picked the larger quantity in a pair of dot arrays in one condition, and the smaller in another. Response latencies to the left and right sides of the screen were compared across the magnitude range...
July 31, 2017: Cognition
https://www.readbyqxmd.com/read/28772130/action-observation-in-the-modification-of-postural-sway-and-gait-theory-and-use-in-rehabilitation
#15
REVIEW
Mitesh Patel
The discovery of cortical neurons responsive to both the observation of another individual's movement and one's own physical movement has spurred scientists into utilising this interplay for rehabilitation. The idea that humans can quickly transfer motor programmes or refine existing motor strategies through observation has only recently gained interest in the context of gait rehabilitation but may offer significant promise as an adjunctive therapy to routine balance training. This review is the first dedicated to action observation in postural control or gait in healthy individuals and patients...
July 24, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28770540/collaborative-remembering-revisited-study-context-access-modulates-collaborative-inhibition-and-later-benefits-for-individual-memory
#16
Magdalena Abel, Karl-Heinz T Bäuml
Collaborating groups typically show reduced recall relative to nominal groups, i.e., to the cumulated non-redundant recall of the same number of people remembering in isolation-a finding termed collaborative inhibition. Motivated by the results of several previous studies, this study examined in two experiments whether access to study context at test influences the effects of collaboration. In both experiments, subjects collaborated in triads or recalled previously studied material in isolation. Experiment 1 applied short versus prolonged retention intervals to vary access to study context at test, whereas Experiment 2 used the list-method directed forgetting task and applied remember versus forget instructions to modulate context access...
August 2, 2017: Memory & Cognition
https://www.readbyqxmd.com/read/28767674/versatile-ion-s5xl-sequencer-for-targeted-next-generation-sequencing-of-solid-tumors-in-a-clinical-laboratory
#17
Meenakshi Mehrotra, Dzifa Yawa Duose, Rajesh R Singh, Bedia A Barkoh, Jawad Manekia, Michael A Harmon, Keyur P Patel, Mark J Routbort, L Jeffrey Medeiros, Ignacio I Wistuba, Rajyalakshmi Luthra
BACKGROUND: Next generation sequencing based tumor tissue genotyping involves complex workflow and a relatively longer turnaround time. Semiconductor based next generation platforms varied from low throughput Ion PGM to high throughput Ion Proton and Ion S5XL sequencer. In this study, we compared Ion PGM and Ion Proton, with a new Ion S5XL NGS system for workflow scalability, analytical sensitivity and specificity, turnaround time and sequencing performance in a clinical laboratory. METHODS: Eighteen solid tumor samples positive for various mutations as detected previously by Ion PGM and Ion Proton were selected for study...
2017: PloS One
https://www.readbyqxmd.com/read/28766714/psychophysiological-responses-of-people-with-psychopathic-tendencies-to-the-concealed-information-test
#18
Hyeon-Gi Hong, Hee-Song Kim, Hyung-Ki Ji, Ki-Pyoung Kim, Jungeun Lee, Sue Hyun Jung, Myoung-Ho Hyun
This study was designed to investigate differences in psychophysiological responses among individuals with psychopathic tendencies. A total 40 students were participated and were divided into two groups based on Levenson Self-Report Psychopathy Scale (LSRP) scores: a high psychopathic tendency group selected from the top 5% of LSRP scores, and a low psychopathic tendency group selected from the bottom 5% of LSRP scores. All participants were instructed to perform a mock crime and complete the concealed information test (CIT)...
August 2, 2017: Journal of Forensic Sciences
https://www.readbyqxmd.com/read/28761942/necrotising-ulcerative-gingivitis-a-literature-review
#19
James Dufty, Nikolaos Gkranias, Nikos Donos
PURPOSE: The literature surrounding necrotising ulcerative gingivitis (NUG) is extensive, yet the rare nature of this disease means that there is a lack of good quality research available. This paper aims to scrutinise the literature and provide an up-to-date summary of the available information. MATERIALS AND METHODS: A literature search was performed electronically using the Cochrane Library, Ovid Medline, Embase, PubMed Clinical Queries and Google Scholar. Keyword searches were carried out, utilising MeSH terms and free text...
July 31, 2017: Oral Health & Preventive Dentistry
https://www.readbyqxmd.com/read/28759309/children-s-accommodation-to-a-variety-of-targets-a-pilot-study
#20
S M Ludden, A M Horwood, P M Riddell
BACKGROUND: Previous research indicates that a significant proportion of children underaccommodate at 1/3 m. Accommodation may vary with task demand, so children may accommodate appropriately if required, for example, when reading small print. This study explores the range of accommodative responses elicited in typical children, under naturalistic conditions, to a range of targets. METHOD: We identified 24 typically developing children from the University of Reading Child Database...
July 31, 2017: Strabismus
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