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https://www.readbyqxmd.com/read/28535481/graphene-oxide-enzyme-hybrid-nanoflowers-for-efficient-water-soluble-dye-removal
#1
Hui Li, Jingwei Hou, Linlin Duan, Chao Ji, Yatao Zhang, Vicki Chen
High efficient enzyme immobilization on carbon based conductive supports could provide wide applications in energy and environmental science. Here, we synthesized a 3D flower-like structured self-assembly hybrid nanocomposite with copper phosphate, laccase, graphite oxide (GO) and carbon nanotubes (CNTs) via a facile one-pot strategy under mild conditions. The prepared nanocomposite exhibited very high enzyme loading and improved laccase activity. During the formation of the nanocomposite, the copper phosphate-laccase petals were interwined by CNTs, and GO nanosheets were further coated on the petal surface...
May 11, 2017: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/28535431/partial-ablation-of-the-pancreas-of-sprague-dawley%C3%A2-rats-by-focused-ultrasound-reveals-no-significant-adverse-effects-on-glycometabolism-function
#2
Lan Ao, Na Hu, Hai Xia Hu, Qing Liu, Zi Hao Zhao, Long Xing Liu, Jun Ru Wu, Fa Qi Li, Liao Qiong Fang
To investigate the safety of focused ultrasound (FUS) partial ablation on the pancreas of Sprague Dawley® (SD) rats by histopathological examination of the outcome and investigation of glycometabolism function changes after local ablation. A total of 135 healthy SD rats were randomly divided into three groups (n=45 of each): FUS ½ group, FUS ¼ group, and control group. Levels of serum amylase was measured using the enzyme dynamics method, fasting blood glucose was measured by the glucose oxidase-peroxidase method, fasting serum insulin was measured by direct chemiluminescence assay, and an ELISA was used to measure fasting serum glucagon immediately after treatment, and at 2h, 3days, 1, 2, 3 and 4weeks, 3 and 6months after FUS ablation...
May 11, 2017: Ultrasonics
https://www.readbyqxmd.com/read/28535357/effects-of-composites-containing-bioactive-glasses-on-demineralized-dentin
#3
A Tezvergil-Mutluay, R Seseogullari-Dirihan, V P Feitosa, G Cama, D S Brauer, S Sauro
The aim of this study was to evaluate the degradation of completely demineralized dentin specimens in contact with a filler-free or 2 ion-releasing resins containing micrometer-sized particles of Bioglass 45S5 (BAG) or fluoride-containing phosphate-rich bioactive glass (BAG-F). Fourier transform infrared spectroscopy (FTIR) and scanning electron microscopy (SEM) were also used to evaluate the remineralization induced by the experimental ion-releasing resin-based materials. Dentin beams were totally demineralized in H3PO4 (10%) and placed in direct contact with a filler-free (RESIN) or 2 experimental ion-releasing resins (BAG or BAG-F) and immersed in artificial saliva (AS) up to 30 d...
May 1, 2017: Journal of Dental Research
https://www.readbyqxmd.com/read/28535128/low-and-high-let-ionizing-radiation-induces-delayed-homologous-recombination-that-persists-for-two-weeks-before-resolving
#4
Christopher P Allen, Hirokazu Hirakawa, Nakako Izumi Nakajima, Sophia Moore, Jingyi Nie, Neelam Sharma, Mayumi Sugiura, Yuko Hoki, Ryoko Araki, Masumi Abe, Ryuichi Okayasu, Akira Fujimori, Jac A Nickoloff
Genome instability is a hallmark of cancer cells and dysregulation or defects in DNA repair pathways cause genome instability and are linked to inherited cancer predisposition syndromes. Ionizing radiation can cause immediate effects such as mutation or cell death, observed within hours or a few days after irradiation. Ionizing radiation also induces delayed effects many cell generations after irradiation. Delayed effects include hypermutation, hyper-homologous recombination, chromosome instability and reduced clonogenic survival (delayed death)...
May 23, 2017: Radiation Research
https://www.readbyqxmd.com/read/28534958/mir-204-regulates-the-biological-behavior-of-breast-cancer-mcf-7-cells-by-directly-targeting-foxa1
#5
Si-Qiao Shen, Lan-Shan Huang, Xiao-Ling Xiao, Xiao-Fei Zhu, Dan-Dan Xiong, Xue-Mei Cao, Kang-Lai Wei, Gang Chen, Zhen-Bo Feng
MicroRNAs (miRNAs) are short, non-protein-coding RNAs and transcripts that are 18-24 nt in length. miR-204 was first identified as an anti-oncogene and is reported to be downregulated in non-small cell lung cancer, glioma, gastric and thyroid cancer. Recent studies have proposed that a low level of miR-204 expression is associated with tumor progression and disease outcome in breast cancer. Forkhead box A1 (FOXA1), a transcription factor, plays a crucial role in breast cancer and has been predicted as a target of miR-204...
May 16, 2017: Oncology Reports
https://www.readbyqxmd.com/read/28534948/dual-strands-of-pre-mir%C3%A2-150-mir%C3%A2-150%C3%A2-5p-and-mir%C3%A2-150%C3%A2-3p-act-as-antitumor-mirnas-targeting-spock1-in-na%C3%A3-ve-and-castration-resistant-prostate-cancer
#6
Atsushi Okato, Takayuki Arai, Satoko Kojima, Keiichi Koshizuka, Yusaku Osako, Tetsuya Idichi, Akira Kurozumi, Yusuke Goto, Mayuko Kato, Yukio Naya, Tomohiko Ichikawa, Naohiko Seki
Analysis of our microRNA (miRNA) expression signature in human cancers has shown that guide and passenger strands of pre-miR‑150, i.e., miR‑150‑5p and miR‑150‑3p, are significantly downregulated in cancer tissues. In miRNA biogenesis, the passenger strand of miRNA is degraded and is thought to have no functions. Thus, the aim of this study was to investigate the functional significance of miR‑150‑5p and miR‑150‑3p in naïve prostate cancer (PCa) and castration-resistant prostate cancer (CRPC)...
May 17, 2017: International Journal of Oncology
https://www.readbyqxmd.com/read/28534944/high-mir-122-expression-promotes-malignant-phenotypes-in-ccrcc-by-targeting-occludin
#7
Kentaro Jingushi, Yuri Kashiwagi, Yuko Ueda, Kaori Kitae, Hiroaki Hase, Wataru Nakata, Kazutoshi Fujita, Motohide Uemura, Norio Nonomura, Kazutake Tsujikawa
Renal cell carcinoma (RCC) is the most common neoplasm of the adult kidney, and clear cell RCC (ccRCC) represents its most common histological subtype. Although several studies have reported high expression of miR-122 in ccRCC, its physiological role remains unclear. To clarify the role of miR-122 in ccRCC, we compared miR-122 expression levels in non-cancerous tissue and ccRCC. Significant upregulation of miR-122 was observed in ccRCC specimens. Moreover, ccRCC patients with high miR-122 expression showed poor progression-free survival compared to those with low miR-122 expression...
May 22, 2017: International Journal of Oncology
https://www.readbyqxmd.com/read/28534875/dose-dependent-social-cognitive-effects-of-intranasal-oxytocin-delivered-with-novel-breath-powered-device-in-adults-with-autism-spectrum-disorder-a-randomized-placebo-controlled-double-blind-crossover-trial
#8
D S Quintana, L T Westlye, S Hope, T Nærland, T Elvsåshagen, E Dørum, Ø Rustan, M Valstad, L Rezvaya, H Lishaugen, E Stensønes, S Yaqub, K T Smerud, R A Mahmoud, P G Djupesland, O A Andreassen
The neuropeptide oxytocin has shown promise as a treatment for symptoms of autism spectrum disorders (ASD). However, clinical research progress has been hampered by a poor understanding of oxytocin's dose-response and sub-optimal intranasal delivery methods. We examined two doses of oxytocin delivered using a novel Breath Powered intranasal delivery device designed to improve direct nose-to-brain activity in a double-blind, crossover, randomized, placebo-controlled trial. In a randomized sequence of single-dose sessions, 17 male adults with ASD received 8 international units (IU) oxytocin, 24IU oxytocin or placebo followed by four social-cognitive tasks...
May 23, 2017: Translational Psychiatry
https://www.readbyqxmd.com/read/28534873/molecular-indicators-of-stress-induced-neuroinflammation-in-a-mouse-model-simulating-features-of-post-traumatic-stress-disorder
#9
S Muhie, A Gautam, N Chakraborty, A Hoke, J Meyerhoff, R Hammamieh, M Jett
A social-stress mouse model was used to simulate features of post-traumatic stress disorder (PTSD). The model involved exposure of an intruder (male C57BL/6) mouse to a resident aggressor (male SJL) mouse for 5 or 10 consecutive days. Transcriptome changes in brain regions (hippocampus, amygdala, medial prefrontal cortex and hemibrain), blood and spleen as well as epigenome changes in the hemibrain were assayed after 1- and 10-day intervals following the 5-day trauma or after 1- and 42-day intervals following the 10-day trauma...
May 23, 2017: Translational Psychiatry
https://www.readbyqxmd.com/read/28534869/advancing-precambrian-palaeomagnetism-with-the-paleomagia-and-pint-qpi-databases
#10
Toni H Veikkolainen, Andrew J Biggin, Lauri J Pesonen, David A Evans, Nicholas A Jarboe
State-of-the-art measurements of the direction and intensity of Earth's ancient magnetic field have made important contributions to our understanding of the geology and palaeogeography of Precambrian Earth. The PALEOMAGIA and PINT(QPI) databases provide thorough public collections of important palaeomagnetic data of this kind. They comprise more than 4,100 observations in total and have been essential in supporting our international collaborative efforts to understand Earth's magnetic history on a timescale far longer than that of the present Phanerozoic Eon...
May 23, 2017: Scientific Data
https://www.readbyqxmd.com/read/28534777/on-the-performance-and-implementation-of-parallax-free-video-see-through-displays
#11
Ricardo Augusto Borsoi, Guilherme Holsbach Costa
In see-through systems an observer watches a (background) scene partially occluded by a display. In this display, usually positioned close to the observer, a region of the background scene is shown, yielding the sensation that the display is transparent. To achieve the transparency effect, it is very important to compensate the parallax error and other distortions caused by the image acquisition system. In this paper a detailed study of a video see-through methodology with parallax correction is performed. In a system composed by two cameras - one directed to the user and another to the background scene - and a display, the relative position between the user, the display and the scene is estimated using a feature detection algorithm and the parallax error is compensated assuming a planar scene model...
May 17, 2017: IEEE Transactions on Visualization and Computer Graphics
https://www.readbyqxmd.com/read/28534732/evaluation-of-adaptive-noise-management-technologies-for-school-age-children-with-hearing-loss
#12
Jace Wolfe, Mila Duke, Erin Schafer, Christine Jones, Lori Rakita
BACKGROUND: Children with hearing loss experience significant difficulty understanding speech in noisy and reverberant situations. Adaptive noise management technologies, such as fully adaptive directional microphones and digital noise reduction, have the potential to improve communication in noise for children with hearing aids. However, there are no published studies evaluating the potential benefits children receive from the use of adaptive noise management technologies in simulated real-world environments as well as in daily situations...
May 2017: Journal of the American Academy of Audiology
https://www.readbyqxmd.com/read/28534625/reaction-mechanisms-of-the-atomic-layer-deposition-of-tin-oxide-thin-films-using-tributyltin-ethoxide-and-ozone
#13
Charith E Nanayakkara, Guo Liu, Abraham Vega, Charles L Dezelah, Ravindra K Kanjolia, Yves J Chabal
Uniform and conformal deposition of tin oxide thin films is important for several applications in electronics, gas sensing and transparent conducting electrodes. Thermal Atomic layer deposition (ALD) is often best suited for these applications, but its implementation requires a mechanistic understanding of the initial nucleation and subsequent ALD processes. To this end, in-situ FTIR and ex-situ XPS have been used to explore the ALD of tin oxide films using tributyltin ethoxide and ozone on an OH-terminated, SiO2-passivated Si(111) substrate...
May 23, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/28534621/spectral-response-of-plasmonic-gold-nanoparticles-to-capacitive-charging-morphology-effects
#14
Benjamin S Hoener, Hui Zhang, Thomas S Heiderscheit, Silke R Kirchner, Agampodi Swarnapali De Silva Indrasekara, Rashad Baiyasi, Yi-Yu Cai, Peter Nordlander, Stephan Link, Christy F Landes, Wei-Shun Chang
We report a study of the shape-dependent spectral response of the gold nanoparticle surface plasmon resonance at various electron densities to provide mechanistic insight into the role of capacitive charging, a topic of some debate. We demonstrate a morphology dependent spectral response for gold nanoparticles due to capacitive charging using single-particle spectroscopy in an inert electrochemical environment. A decrease in plasmon energy and increase in spectral width for gold nanospheres and nanorods was observed as the electron density was tuned through a potential window of -0...
May 23, 2017: Journal of Physical Chemistry Letters
https://www.readbyqxmd.com/read/28534619/quantitative-solid-state-nmr-study-on-ligand-surface-interaction-in-cysteine-capped-cdse-magic-sized-clusters
#15
Takuya Kurihara, Yasuto Noda, Kiyonori Takegoshi
Ligand-surface interaction of semiconductor nanoparticles (NPs) controls their optoelectronic properties, and thus examinations of the interaction are essential for the nanoelectronic applications of NPs. Herein, solid-state nuclear magnetic resonance (NMR) is performed to unravel the ligand-surface interaction in cysteine-capped CdSe magic-sized clusters. (15)N-(113)Cd through-bond J-filtered NMR directly shows the presence of the nitrogen-cadmium chemical bond for the first time and indicates that ~43% of the amines form the chemical bond...
May 23, 2017: Journal of Physical Chemistry Letters
https://www.readbyqxmd.com/read/28534574/syntheses-structures-and-magnetic-properties-of-a-family-of-end-on-azido-bridged-cu-ii-ln-iii-complexes
#16
Xing-Cai Huang, Xin-Hua Zhao, Dong Shao, Xin-Yi Wang
The reaction of Cu(valdmpn) (H2valdmpn = N,N'-bis-(3-methoxysalicylidene)-1,3-diamino-2,2-dimethylpropane), LnCl3·nH2O (Ln = La(1), Ce (2), Pr(3), Nd(4), Sm(5), Eu(6), Gd(7), Tb(8), Dy(9), Ho(10), Er(11), Tm(12), Yb(13), Lu(14)) and NaN3 in methanol led to a whole series of heterometallic Cu(II)-Ln(III) complexes. The basic structural components of these complexes are the [Cu(II)(valdmpn)Ln(III)] units with a compartmental Schiff-base ligand. These [Cu(II)Ln(III)] units were then further connected by the end-on (EO) azides between the Ln(3+) centers to form tetranuclear {[CuLn](μ-N3)n[LnCu]} motifs, where n is 3 for the complexes of larger radii lanthanides (1CuLa to 5CuSm) and 2 for the complexes of smaller radii lanthanides (6CuEu to 14CuLu)...
May 23, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/28534560/re-configurable-multi-mode-contained-electrospray-ionization-for-protein-folding-and-unfolding-on-the-millisecond-time-scale
#17
Colbert F Miller, Dmytro S Kulyk, Jongin W Kim, Abraham K Badu-Tawiah
A new reconfigurable contained-electrospray (ES) ion source is described that can be operated in three unique modes (Types I, II and III) and was applied to control the charge state of proteins for subsequent online characterization by mass spectrometry. Using this device, proteins prepared in 100% water were highly charged after exposure to hydrochloric acid vapor. For myoglobin, the shift to a higher charge state occurred faster than the heme cofactor could escape the unfolding protein. This effect reflected in the detection of highly charged holo-myoglobin intermediates (+26), which suggests the modification process occurred on a millisecond time scale (Type I mode)...
May 23, 2017: Analyst
https://www.readbyqxmd.com/read/28534516/transcriptional-and-posttranscriptional-regulation-of-hoxa13-by-lncrna-hottip-facilitates-tumorigenesis-and-metastasis-in-esophageal-squamous-carcinoma-cells
#18
C Lin, Y Wang, Y Wang, S Zhang, L Yu, C Guo, H Xu
The long non-coding RNA, HOTTIP, has an important role in tumorigenesis. It is known that HOTTIP regulates HOX gene family; however, its regulatory mechanism in esophageal squamous cell carcinoma (ESCC) remains elusive. In this study, we investigated the role of HOTTIP in ESCC and observed that HOTTIP/HOXA13 was upregulated in ESCC and promoted cell proliferation and metastasis in vivo and in vitro. Interestingly, harboring a miR-30b-binding site, HOTTIP as a molecular sponge mainly regulated miR-30b level in the nucleus and modulated the repression of HOXA13 mediated by miR-30b in the cytoplasm, resulting in the positive HOTTIP/HOXA13 correlation...
May 22, 2017: Oncogene
https://www.readbyqxmd.com/read/28534501/electronic-evidence-of-temperature-induced-lifshitz-transition-and-topological-nature-in-zrte5
#19
Yan Zhang, Chenlu Wang, Li Yu, Guodong Liu, Aiji Liang, Jianwei Huang, Simin Nie, Xuan Sun, Yuxiao Zhang, Bing Shen, Jing Liu, Hongming Weng, Lingxiao Zhao, Genfu Chen, Xiaowen Jia, Cheng Hu, Ying Ding, Wenjuan Zhao, Qiang Gao, Cong Li, Shaolong He, Lin Zhao, Fengfeng Zhang, Shenjin Zhang, Feng Yang, Zhimin Wang, Qinjun Peng, Xi Dai, Zhong Fang, Zuyan Xu, Chuangtian Chen, X J Zhou
The topological materials have attracted much attention for their unique electronic structure and peculiar physical properties. ZrTe5 has host a long-standing puzzle on its anomalous transport properties manifested by its unusual resistivity peak and the reversal of the charge carrier type. It is also predicted that single-layer ZrTe5 is a two-dimensional topological insulator and there is possibly a topological phase transition in bulk ZrTe5. Here we report high-resolution laser-based angle-resolved photoemission measurements on the electronic structure and its detailed temperature evolution of ZrTe5...
May 23, 2017: Nature Communications
https://www.readbyqxmd.com/read/28534476/effect-of-short-message-service-on-management-of-pulmonary-tuberculosis-patients-in-anhui-province-china-a-prospective-randomized-controlled-study
#20
Xue-Hui Fang, Shi-Yang Guan, Li Tang, Fang-Biao Tao, Zheng Zou, Ji-Xiang Wang, Xiao-Hong Kan, Quan-Zhi Wang, Zhi-Ping Zhang, Hong Cao, Dong-Chun Ma, Hai-Feng Pan
BACKGROUND To explore the significance of short message service (SMS) on the management of pulmonary tuberculosis (TB) patients in reinforcing the treatment adherence and health awareness, and provide scientific evidences for popularizing this model and formulating related polices and measures. MATERIAL AND METHODS Six counties (districts) were selected by stratified cluster sampling method, and randomly divided into control group and intervention group. Pulmonary TB patients eligible to the study criteria were included in the study...
May 23, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
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