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https://www.readbyqxmd.com/read/28726260/three-year-experience-with-interventional-neuroradiology-for-management-of-cerebral-aneurysms-at-a-single-australian-centre
#1
Aden McLaughlin, Hal Rice, Laetitia de Viliers, Teresa Withers, David Pearson, Moira Arnell, Kerin Walters, Sarah Czuchwicki, Andrew Bulmer, James Winearls
INTRODUCTION: Over the last decade interventional neuroradiology (NR) has become the mainstay of managing cerebral aneurysms. The aim of our study was to review our growing experiences with interventional NR and quantify morbidity and mortality associated with these procedures. METHODS: The electronic medical records of all patients admitted to the Gold Coast (University) Hospital Intensive Care Unit following subarachnoid haemorrhage (SAH) or elective interventional NR management of cerebral aneurysms between January 2012 and December 2014 were retrieved...
July 20, 2017: Journal of Medical Imaging and Radiation Oncology
https://www.readbyqxmd.com/read/28726048/is-ct-perfusion-helpful-in-the-treatment-allocation-of-patients-with-acute-ischemic-stroke-an-expert-opinion-analysis
#2
Laura Strada, Jonathan Y Streifler, Bruno Del Sette, Matteo Puntoni, Antonio Castaldi, Daria Bianchini, Massimo Del Sette
BACKGROUND: Intravenous tPA is the standard treatment for acute ischemic stroke within 4.5 hours of symptom onset. Neuroradiological selection is currently based upon non-contrast- brain CT scan (NCCT). AIMS: To verify, in an "expert-opinion setting", the possible usefulness of CT perfusion (CTP) in decision-making toward i.v. thrombolysis. PATIENTS AND METHOD: One hundred and three consecutive patients with acute ischemic stroke who underwent NCCT and CTP were re-evaluated by an expert in cerebrovascular disease, to verify if adding CTP information would have changed expert's opinion...
July 19, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28722300/digital-subtraction-angiography-dynavision-in-pretreatment-planning-for-embolization-of-dural-arterio-venous-fistulas
#3
Alex Botsford, Jai Jai Shiva Shankar
BACKGROUND AND PURPOSE: We have found DSA-Dynavision with multiplanar reconstruction very helpful in understanding the complex anatomy and planning of treatment of carotico-cavernous fistulas. The purpose of our study was to examine whether using DSA-Dynavision in pretreatment planning results in better outcome after endovascular treatment of dural arterio-venous fistulas (dAVFs). METHODS: Patients with dAVF treated with endovascular embolization were retrospectively identified from our interventional neuroradiology database...
July 19, 2017: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/28719391/pediatric-and-congenital-hand-transplantation
#4
Sandra Amaral, L Scott Levin
PURPOSE OF REVIEW: We review the approach and challenges associated with pediatric hand transplantation, including new knowledge gleaned from our recent case of bilateral hand-forearm transplantation in an 8-year old child. RECENT FINDINGS: Bilateral heterologous hand-forearm transplantation was performed in a child with a prior kidney transplant in July 2015. The initial surgery necessitated a large team of experts in microvascular surgery, transplant surgery, orthopedics and plastic surgery as well as pediatric anesthesia...
July 14, 2017: Current Opinion in Organ Transplantation
https://www.readbyqxmd.com/read/28717351/serial-sampling-of-serum-protein-biomarkers-for-monitoring-human-traumatic-brain-injury-dynamics-a-systematic-review
#5
REVIEW
Eric Peter Thelin, Frederick Adam Zeiler, Ari Ercole, Stefania Mondello, András Büki, Bo-Michael Bellander, Adel Helmy, David K Menon, David W Nelson
BACKGROUND: The proteins S100B, neuron-specific enolase (NSE), glial fibrillary acidic protein (GFAP), ubiquitin carboxy-terminal hydrolase L1 (UCH-L1), and neurofilament light (NF-L) have been serially sampled in serum of patients suffering from traumatic brain injury (TBI) in order to assess injury severity and tissue fate. We review the current literature of serum level dynamics of these proteins following TBI and used the term "effective half-life" (t1/2) in order to describe the "fall" rate in serum...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28711213/dual-energy-computed-tomography-in-neuroradiology-and-head-and-neck-imaging-state-of-the-art
#6
EDITORIAL
Reza Forghani, Hillary R Kelly
No abstract text is available yet for this article.
August 2017: Neuroimaging Clinics of North America
https://www.readbyqxmd.com/read/28711200/dual-energy-computed-tomography-physical-principles-approaches-to-scanning-usage-and-implementation-part-2
#7
REVIEW
Reza Forghani, Bruno De Man, Rajiv Gupta
There are increasing applications and use of spectral computed tomography or dual-energy computed tomography (DECT) in neuroradiology and head and neck imaging in routine clinical practice. Part 1 of this 2-part review covered fundamental physical principles underlying DECT scanning and the different approaches for scanning. Part 2 focuses on important and practical considerations for implementing and using DECT in clinical practice, including a review of different images and reconstructions produced by these scanners and important and practical issues, ranging from image quality and radiation dose to workflow-related aspects of DECT scanning, that routinely come up during operationalization of DECT...
August 2017: Neuroimaging Clinics of North America
https://www.readbyqxmd.com/read/28711199/dual-energy-computed-tomography-physical-principles-approaches-to-scanning-usage-and-implementation-part-1
#8
REVIEW
Reza Forghani, Bruno De Man, Rajiv Gupta
There are increasing applications of dual-energy computed tomography (CT), a type of spectral CT, in neuroradiology and head and neck imaging. In this 2-part review, the fundamental principles underlying spectral CT scanning and the major considerations in implementing this type of scanning in clinical practice are reviewed. In the first part of this 2-part review, the physical principles underlying spectral CT scanning are reviewed, followed by an overview of the different approaches for spectral CT scanning, including a discussion of the strengths and challenges encountered with each approach...
August 2017: Neuroimaging Clinics of North America
https://www.readbyqxmd.com/read/28707434/utility-of-digital-subtraction-angiography-based-collateral-evaluation-in-medically-treated-acute-symptomatic-basilar-artery-stenosis
#9
W-J Lee, K-H Jung, Y J Ryu, J-M Kim, S-T Lee, K Chu, M Kim, S K Lee, J-K Roh
BACKGROUND AND PURPOSE: Although a stroke from atherosclerosis in the basilar artery (BA) often presents with mild initial stroke severity, it has heterogeneous clinical courses. We investigated the efficacy of digital subtraction angiography (DSA)-based collateral perfusion evaluation in association with long-term outcomes of medically treated symptomatic basilar artery stenosis. METHODS: From a registry database of all consecutive patients with stroke, we included 98 medically treated patients (due to mild initial stroke severity) [National Institute of Health Stroke Scale (NIHSS) scores ≤ 4; symptomatic basilar artery stenosis, 70-99%] with available initial diagnostic DSA...
July 14, 2017: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/28706764/neuroradiological-endovascular-intervention-for-diplopia-in-a-case-of-aneurysmal-aberrant-regeneration-of-the-third-nerve
#10
Anupam C A Rao, Saumil A Shah, Benjamin W C Sim, Steven T H Yun, Neeranjali S Jain, Yashar Kalani, Ian C Francis
Aberrant regeneration of the third nerve occurs as a result of synkinetic 'miswiring' of the third nerve following its injury, such as in third cranial nerve palsy due to tumor, trauma, or aneurysm. The case presented is an elderly woman with new vertical diplopia, which led to a diagnosis of a third cranial nerve palsy, thought to be caused by a 5 mm blister aneurysm of the posterior communicating artery. However, neuro-ophthalmological evaluation diagnosed aberrant regeneration of the third nerve, with the cause of her new vertical diplopia being an ipsilateral fourth nerve palsy...
June 12, 2017: Curēus
https://www.readbyqxmd.com/read/28706116/training-standards-in-neuroendovascular-surgery-program-accreditation-and-practitioner-certification
#11
REVIEW
Arthur L Day, Adnan H Siddiqui, Philip M Meyers, Tudor G Jovin, Colin P Derdeyn, Brian L Hoh, Howard Riina, Italo Linfante, Osama Zaidat, Aquilla Turk, Jay U Howington, J Mocco, Andrew J Ringer, Erol Veznedaroglu, Alexander A Khalessi, Elad I Levy, Henry Woo, Robert Harbaugh, Steven Giannotta
BACKGROUND AND PURPOSE: Neuroendovascular surgery is a medical subspecialty that uses minimally invasive catheter-based technology and radiological imaging to diagnose and treat diseases of the central nervous system, head, neck, spine, and their vasculature. To perform these procedures, the practitioner needs an extensive knowledge of the anatomy of the nervous system, vasculature, and pathological conditions that affect their physiology. A working knowledge of radiation biology and safety is essential...
July 13, 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/28697713/an-update-of-the-italian-stroke-organization-stroke-prevention-awareness-diffusion-group-guidelines-on-carotid-endarterectomy-and-stenting-a-personalized-medicine-approach
#12
Gaetano Lanza, Carlo Setacci, Stefano Ricci, Patrizio Castelli, Alberto Cremonesi, Jessica Lanza, Claudio Novali, Carlo Pratesi, Paola Santalucia, Francesco Speziale, Augusto Zaninelli, Gian Franco Gensini
Although proof-based medicine has generated much valid evidence for the drawing up of guidelines and recommendations for best clinical practice in symptomatic and asymptomatic carotid stenosis, whether and when it is better to employ endarterectomy or stenting as the intervention of choice still remain matters of debate. Moreover, guidelines have been targeted up to now to the 'representative' patient, as resulting from the statistical analyses of the studies conducted on the safety and efficacy of both interventions as well as on medical therapy alone...
July 2017: International Journal of Stroke: Official Journal of the International Stroke Society
https://www.readbyqxmd.com/read/28697194/enhancing-contrast-agents-and-radiotracers-performance-through-hyaluronic-acid-coating-in-neuroradiology-and-nuclear-medicine
#13
Mario Ganau, Nikolaos Ch Syrmos, Felice D'Arco, Laura Ganau, Salvatore Chibbaro, Lara Prisco, Gianfranco K I Ligarotti, Rossano Ambu, Andrea Soddu
The use of hyaluronic acid nanoshells has been proposed to encapsulate prodrugs and exploit the mechanisms of interactions between living cells, like endocytes or cancer cells and hyaluronic acid, which is a natural component of the extracellular matrix. In this review we describe the potential and the limits of this promising research trend and discuss the theoretical advantages of such an engineering approach. Is it a possible scalability to increase the efficacy and biodegradability of molecules like contrast media and radiotracers especially for neuroradiology and nuclear medicine studies...
July 12, 2017: Hellenic Journal of Nuclear Medicine
https://www.readbyqxmd.com/read/28695340/tropomyosin-receptor-kinase-c-trkc-expression-in-medulloblastoma-relation-to-the-molecular-subgroups-and-impact-on-treatment-response
#14
Carsten Friedrich, Tarek Shalaby, Christoph Oehler, Martin Pruschy, Burkhardt Seifert, Daniel Picard, Marc Remke, Monika Warmuth-Metz, Rolf-Dieter Kortmann, Stefan Rutkowski, Michael A Grotzer, André O von Bueren
PURPOSE: High messenger RNA (mRNA) expression of the tropomyosin receptor kinase C gene (TrkC) has been associated with favorable survival in medulloblastoma patients. Untested is whether it plays a role through modulating the response to therapy or whether it might be a surrogate marker for a favorable molecular subgroup. METHODS: The medulloblastoma-derived cell line DAOY was stably transfected to overexpress TrkC (clone DAOY-TrkC) and compared to a control (clone DAOY-EV, empty vector transfected)...
July 10, 2017: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/28686357/homozygous-null-variant-in-cradd-encoding-an-adaptor-protein-that-mediates-apoptosis-is-associated-with-lissencephaly
#15
Tamar Harel, Nuphar Hacohen, Avraham Shaag, Moshe Gomori, Amihood Singer, Orly Elpeleg, Vardiella Meiner
Lissencephaly is a severe malformation of cortical development, most often attributed to abnormalities in neuronal migration. It is associated with a severe prognosis including developmental delay, intellectual disability, and seizures. Lissencephaly can be reliably diagnosed during late gestation by neurosonography or fetal magnetic resonance imaging (MRI). We report two sibling male fetuses who were diagnosed with delayed cortical sulcation highly suggestive of lissencephaly during late pregnancy. After receiving genetic counseling, the parents elected to terminate the pregnancies based on the neuroradiological findings and the associated severe prognosis...
July 7, 2017: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/28684458/influence-of-carotid-siphon-anatomy-on-brain-aneurysm-presentation
#16
E Waihrich, P Clavel, G A C Mendes, C Iosif, I Moraes Kessler, C Mounayer
BACKGROUND AND PURPOSE: Intracranial aneurysm is a devastating disease of complex etiology that is not fully understood. The purpose of this study was to assess the implications of carotid siphon anatomy for the formation and development of intracranial aneurysms. MATERIALS AND METHODS: Between January 2007 and May 2015, lateral view digital subtraction angiographic images of 692 consecutive patients with intracranial aneurysms treated in our department of interventional neuroradiology were reviewed and had their angles measured...
July 6, 2017: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/28678215/intercorrelations-of-morphology-with-hemodynamics-in-intracranial-aneurysms-in-computational-fluid-dynamics
#17
Tianlun Qiu, Guoliang Jin, Wuqiao Bao, Haitao Lu
OBJECTIVE: To measure morphological indices and wall shear stress (WSS) of aneurysms and parent artery surface in order to explore the relationship of morphological characteristics and WSS. METHODS: Data from 47 events of consecutive cerebral saccular aneurysms from 39 patients which were referred to the interventional Neuroradiology service of the Shaoxing People`s Hospital, Shaoxing, China between 2014 April and 2015 August. Wall shear stress and wall pressure (WP) of the pre-aneurysm, aneurysm and near vessel (<1...
July 2017: Neurosciences: the Official Journal of the Pan Arab Union of Neurological Sciences
https://www.readbyqxmd.com/read/28676141/hla-drb1-15-association-with-multiple-sclerosis-is-confirmed-in-a-multigenerational-italian-family
#18
L Mosca, V Mantero, S Penco, L La Mantia, S De Benedetti, M R Marazzi, C Spreafico, C Erminio, L Grassi, G Lando, M Zagaria, E Agostoni, A Protti
Environmental and genetic factors seem to play a pathogenetic role in multiple sclerosis (MS). The genetic component is partly suggested by familial aggregation of cases; however, MS families with affected subjects over different generations have rarely been described. The aim of this study was to report clinical and genetic features of a multigenerational MS family and to perform a review of the literature on this topic. We describe a multigenerational Italian family with six individuals affected by MS, showing different clinical and neuroradiological findings...
April 2017: Functional Neurology
https://www.readbyqxmd.com/read/28673776/private-practice-radiologist-subspecialty-classification-using-medicare-claims
#19
Andrew B Rosenkrantz, Wenyi Wang, Sudheshna Bodapati, Danny R Hughes, Richard Duszak
PURPOSE: The aim of this study was to assess both existing Medicare provider code assignments and a new claims-based system for subspecialty classification of private practice radiologists. METHODS: Websites of the 100 largest US radiology private practices were used to identify 1,476 radiologists self-identified with a single subspecialty ([1] abdominal, [2] breast, [3] cardiothoracic, or [4] musculoskeletal imaging; [5] nuclear medicine; [6] interventional radiology; [7] neuroradiology)...
June 30, 2017: Journal of the American College of Radiology: JACR
https://www.readbyqxmd.com/read/28673029/predictive-factors-of-surgical-outcome-in-frontal-lobe-epilepsy-explored-with-stereoelectroencephalography
#20
Francesca Bonini, Aileen McGonigal, Didier Scavarda, Romain Carron, Jean Régis, Henry Dufour, Jean-Claude Péragut, Virginie Laguitton, Nathalie Villeneuve, Patrick Chauvel, Bernard Giusiano, Agnès Trébuchon, Fabrice Bartolomei
BACKGROUND: Resective surgery established treatment for pharmacoresistant frontal lobe epilepsy (FLE), but seizure outcome and prognostic indicators are poorly characterized and vary between studies. OBJECTIVE: To study long-term seizure outcome and identify prognostic factors. METHODS: We retrospectively analyzed 42 FLE patients having undergone surgical resection, mostly preceded by invasive recordings with stereoelectroencephalography (SEEG)...
June 29, 2017: Neurosurgery
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