keyword
https://read.qxmd.com/read/38635874/the-better-operative-outcomes-software-tool-boost-prospective-study-improving-the-quality-of-cataract-surgery-outcomes-in-low-resource-settings
#1
JOURNAL ARTICLE
Myra B McGuinness, Elise Moo, Beatrice Varga, Sarity Dodson, Van Charles Lansingh, Serge Resnikoff, Elena Schmidt, Thulasiraj Ravilla, Ganesh-Babu Balu Subburaman, Rohit C Khanna, Varsha M Rathi, Simon Arunga, Hans Limburg, Nathan Congdon
PURPOSE: Post-operative vision impairment is common among patients who have undergone cataract surgery in low-resource settings, impacting quality of clinical outcomes and patient experience. This prospective, multisite, single-armed, pragmatic validation study aimed to assess whether receiving tailored recommendations via the free Better Operative Outcomes Software Tool (BOOST) app improved surgical outcomes, as quantified by post-operative unaided distance visual acuity (UVA) measured 1-3 days after surgery...
April 18, 2024: Ophthalmic Epidemiology
https://read.qxmd.com/read/38635847/influence-of-intergenerational-support-on-the-mental-health-of-older-people-in-china
#2
JOURNAL ARTICLE
Zicheng Jiang, Huan Liu, Jing Deng, Yizhong Ye, Dexun Li
Today, population aging is the main trend of population development. Home-based care is mainly adopted in Chinese society, and scholars have paid ample attention to the effect of intergenerational support on the mental health of older people. However, research conclusions differ. This study uses data from the 2018 China Health and Pension Tracking Survey (CHARLS), which we analyzed with STATA software to construct least squares regression and two-stage least squares regression models. The regression model included 6,647 respondents to investigate the mental health status of older people based on depression status...
2024: PloS One
https://read.qxmd.com/read/38635840/impact-of-conflict-on-the-elimination-targets-of-lymphatic-filariasis-schistosomiasis-and-soil-transmitted-helminths-in-cabo-delgado-province-mozambique
#3
JOURNAL ARTICLE
Xavier Badia-Rius, Henis Mior Sitoe, Sergio Lopes, Louise A Kelly-Hope
BACKGROUND: Mozambique has one of the highest burdens of neglected tropical diseases in Africa. Lymphatic filariasis, schistosomiasis and soil-transmitted helminths are being targeted for elimination as part of integrated mass drug administration campaigns. The progress made towards interruption of transmission has been affected by recent conflict in Cabo Delgado province. The aim of this paper was to determine the potential impact of this crisis on the neglected tropical diseases programme and the challenges in reaching the elimination goals of 2030...
April 18, 2024: PLoS Neglected Tropical Diseases
https://read.qxmd.com/read/38635828/variable-angle-of-insulated-shotcrete-under-different-loading-rates-and-temperature-and-humidity-cycles-shear-test-and-analysis
#4
JOURNAL ARTICLE
Gejun Tong, Jingzhao Shen, Jianyong Pang, Haotian Shi, Jinkun Huang
The new thermal insulating shotcrete is of great significance for the management of thermal damage in deep mines, and its own strength has a greater impact on the roadway insulation and safe production, so it is very necessary to study the shear strength of the new thermal insulating shotcrete under the influence of the deep hot and humid environment and the stress of mining. For the heat-insulating shotcrete, firstly, we carried out the concrete variable angle shear test under different loading rates, which concluded that the shear rate and peak shear stress showed a trend of increasing and then decreasing; as the angle increases, the different rates have a greater impact on the peak shear stress of the specimen...
2024: PloS One
https://read.qxmd.com/read/38635760/factors-associated-with-mortality-of-elderly-people-due-to-covid-19-protocol-for-systematic-review-and-meta-analysis
#5
JOURNAL ARTICLE
Danyllo do Nascimento Silva Junior, Ádala Nayana de Sousa Mata, Gidyenne Christine Bandeira Silva de Medeiros, Marilane Vilela Marques, Thais Teixeira Dos Santos, Maria Eduarda de Sousa Monteiro, Gabriela Góis Costa, Eleonora D Orsi, Eva Vegue Parra, Grasiela Piuvezam
INTRODUCTION: The COVID-19 pandemic has become a significant health crisis, marked by high mortality rates on a global scale, with mortality from the disease being notably concentrated among the elderly due to various factors. OBJECTIVE: This study aims to investigate the biological and non-biological factors associated with COVID-19 mortality rates among the elderly worldwide. METHODS: The following databases will be consulted: PubMed, Scopus, EMBASE, Web of Science and ScienceDirect...
2024: PloS One
https://read.qxmd.com/read/38635722/analysis-of-football-research-trends-using-text-network-analysis
#6
JOURNAL ARTICLE
Jongwon Kim
This study was aimed to identify football research trends in various periods. A total of 30,946 football papers were collected from a representative academic database and search engine, the 'Web of Science'. Keyword refinement included filtering nouns, establishing synonyms and thesaurus, and excluding conjunctions, and the Cyram's Netminer 4.0 software was used for network analysis. A centrality analysis was conducted by extracting the words corresponding to the top 2% of the main research topics to obtain the degree and eigenvector centralities...
2024: PloS One
https://read.qxmd.com/read/38635686/an-open-platform-for-visual-stimulation-of-insects
#7
JOURNAL ARTICLE
Stefan Prech, Lukas N Groschner, Alexander Borst
To study how the nervous system processes visual information, experimenters must record neural activity while delivering visual stimuli in a controlled fashion. In animals with a nearly panoramic field of view, such as flies, precise stimulation of the entire visual field is challenging. We describe a projector-based device for stimulation of the insect visual system under a microscope. The device is based on a bowl-shaped screen that provides a wide and nearly distortion-free field of view. It is compact, cheap, easy to assemble, and easy to operate using the included open-source software for stimulus generation...
2024: PloS One
https://read.qxmd.com/read/38635666/research-on-the-generative-logic-and-configuration-effects-of-the-policy-implementation-environment-in-china-s-grassroots-digital-construction-traceability-based-on-grounded-theory-and-the-validation-of-the-csqca-method
#8
JOURNAL ARTICLE
Junjie Li, Bangfan Liu
Using NVivo12plus software, this study constructs a generation model of the policy implementation environment in China's grassroots digital construction by examining the data from interviews with 37 Chinese grassroots civil servants as its research object. At the same time, with the help of the csQCA method and on the basis of rooted coding, using Tosmana software, the model validation and model expansion of 37 cases were carried out. This study shows that the main components of the policy implementation environment in China's grassroots digital construction include five main dimensions: cognitive, emotional, behavioral, normative and control...
2024: PloS One
https://read.qxmd.com/read/38635643/spatial-distribution-and-associated-factors-of-co-occurrence-of-overweight-obesity-and-anemia-among-women-in-the-reproductive-age-in-sub-saharan-africa-a-multilevel-analysis-dhs-2016-2021
#9
JOURNAL ARTICLE
Mihret Getnet, Wullo Sisay Sisay, Adugnaw Zeleke Alem
BACKGROUND: Overweight/obesity is one of the major public health problems that affect both developed and developing nations. The co-occurrence of overweight/obesity and anemia is thought to be largely preventable if detected early. To date, no spatial analyses have been performed to identify areas of hotspots for the co-occurrence of overweight/obesity and anemia among reproductive women in sub-Saharan Africa. Therefore, this study aimed to assess the spatial distribution and associated factors of the co-occurrence of overweight/obesity and anemia among women of reproductive age...
2024: PloS One
https://read.qxmd.com/read/38635622/whole-genome-analysis-of-human-mastadenovirus-d-causing-keratoconjunctivitis-in-india-a-multicentre-study
#10
JOURNAL ARTICLE
Ferdinamarie S Philomenadin, Mini P Singh, Jayanthi Shastri, Anil C Phukan, Muruganandam Nagarajan, Subashini Kaliaperumal, Radha Kanta Ratho, Jagat Ram, Madhav J Sathe, Avinash Ingole, Darshana B Rathod, Benjamin Nongrum, Rehnuma Parvez, Vineeta Malik, Rahul Dhodapkar
INTRODUCTION: Human mastadenovirus (HAdV) types 8, 37, 64 have been considered the major contributors in Epidemic keratoconjunctivitis (EKC) epidemics, but recent surveillance data have shown the involvement of emerging recombinants, including HAdV-53, HAdV-54, and HAdV-56. In our initial work, positive samples for adenovirus revealed that our strains were closer to HAdV-54 than HAdV-8. Hence, the current study aimed to use whole genome technology to identify the HAdV strain correctly...
March 31, 2024: Journal of Infection in Developing Countries
https://read.qxmd.com/read/38635512/validation-and-analysis-of-the-metric-properties-of-the-leadership-virtues-questionnaire-in-work-and-organizational-psychologists-and-individuals-who-perform-leadership-functions-in-chile
#11
JOURNAL ARTICLE
Pablo Livacic-Rojas, María José Rodríguez-Araneda
The literature on leadership and personal competencies exhibits limitations in terms of construct definition, behavior specifications and valid theory-based measuring strategies. An explanatory design with latent variables and the statistical software SAS 9.4 were used for the validation and adaptation to Spanish of the Leadership Virtues Questionnaire applied to work and organizational psychologists and people who exercise leadership functions in Chile. The levels of agreement between judges for the adaptation to the Spanish language and the confirmatory factor analysis of first order with four dimensions shows insufficient statistical indices for the absolute, comparative and parsimonious adjustments...
2024: PloS One
https://read.qxmd.com/read/38635396/protocol-for-evaluating-the-effect-of-potential-on-electrochemical-reactions-via-the-grand-canonical-fixed-potential-technique
#12
JOURNAL ARTICLE
Guoping Gao, Lin-Wang Wang
The grand canonical constant potential approach is a cornerstone for modeling the electrochemical reactions under work conditions. Here, we present a protocol for evaluating the effect of potential on electrochemical reactions using the grand canonical fixed-potential technique. We describe steps for installing PWmat software, preparing input files for the fixed-potential calculation, and simulating different electrochemical states under the same potential. We then detail procedures for analyzing the free energy evolution under the same potential...
April 16, 2024: STAR protocols
https://read.qxmd.com/read/38635019/ultrasound-surveillance-in-melanoma-management-bridging-diagnostic-promise-with-real-world-adherence-a-systematic-review-and-meta-analysis
#13
Zhao Feng Liu, Amy Sylivris, Johnny Wu, Darren Tan, Samuel Hong, Lawrence Lin, Michael Wang, Christopher Chew
BACKGROUND: Ultrasound surveillance has become the new standard of care in stage III melanoma after the 2017 Multicenter Selective Lymphadenectomy Trial II (MSLT-II) demonstrated non-inferior 3-year survival compared with complete lymph node dissection. OBJECTIVE: We aimed to quantify diagnostic performance and adherence rates of ultrasound surveillance for melanoma locoregional metastasis, offering insights into real-world applicability. METHODS: Conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines, we systematically searched the Medline, Embase, Cochrane Library, CINAHL, Scopus, and Web of Science databases from inception until 11 October 2023...
April 18, 2024: American Journal of Clinical Dermatology
https://read.qxmd.com/read/38635014/irf4-knockdown-inhibits-the-chronic-rhinosinusitis-without-nasal-polyps-development-by-regulating-nlrp3-caspase-1-gsdmd-mediated-pyroptosis
#14
JOURNAL ARTICLE
Jun Xu, Jiahui Li, Xiaoya Wang, Yunsong An, Wenlong Liu, Renzhong Luo, Changzhi Sun
Chronic rhinosinusitis without nasal polyps (CRSsNP) is a CRS phenotype. However, the mechanisms of CRSsNP remains unclear. Differentially expressed genes (DEGs) were obtained from the GSE36830 and GSE198950 datasets through the GEO2R tool. The six hub genes were screened by the protein-protein interaction (PPI) network analysis and Cytoscape software. Then we constructed the mouse models of CRS and verified the expression levels of hub genes by reverse transcription quantitative PCR (RT-qPCR). Hematoxylin-eosin (HE) staining was employed to observe pathological alterations in mouse tissues...
April 18, 2024: Biochemical Genetics
https://read.qxmd.com/read/38634946/proposed-molecular-mechanism-of-non-competitive-inhibition-using-molecular-dynamics-simulations-between-%C3%AE-glucosidase-enzyme-and-mangostin-compound-as-antidiabetic
#15
JOURNAL ARTICLE
Ahmad Fariz Maulana, Iman Permana Maksum, Sriwidodo Sriwidodo, Yaya Rukayadi
CONTEXT: Further understanding of the molecular mechanisms is necessary since it is important for designing new drugs. This study aimed to understand the molecular mechanisms involved in the design of drugs that are inhibitors of the α-glucosidase enzyme. This research aims to gain further understanding of the molecular mechanisms underlying antidiabetic drug design. The molecular docking process yielded 4 compounds with the best affinity energy, including γ-Mangostin, 1,6-dimethyl-ester-3-isomangostin, 1,3,6-trimethyl-ester-α-mangostin, and 3,6,7-trimethyl-ester-γ-mangostin...
April 18, 2024: Journal of Molecular Modeling
https://read.qxmd.com/read/38634943/a-comparative-analysis-of-deep-learning-based-location-adaptive-threshold-method-software-against-other-commercially-available-software
#16
JOURNAL ARTICLE
Daebeom Park, Eun-Ah Park, Baren Jeong, Whal Lee
Automatic segmentation of the coronary artery using coronary computed tomography angiography (CCTA) images can facilitate several analyses related to coronary artery disease (CAD). Accurate segmentation of the lumen or plaque region is one of the most important factors. This study aimed to analyze the performance of the coronary artery segmentation of a software platform with a deep learning-based location-adaptive threshold method (DL-LATM) against commercially available software platforms using CCTA. The dataset from intravascular ultrasound (IVUS) of 26 vessel segments from 19 patients was used as the gold standard to evaluate the performance of each software platform...
April 18, 2024: International Journal of Cardiovascular Imaging
https://read.qxmd.com/read/38634935/effect-of-compressive-strain-on-electronic-and-optical-properties-of-cr-doped-monolayer-ws-2
#17
JOURNAL ARTICLE
Yansong Mu, Guili Liu, Ran Wei, Guoying Zhang
CONTEXT: The electronic properties and optical properties of Cr-doped monolayer WS2 under uniaxial compressive deformation have been investigated based on density functional theory. In terms of electronic structure properties, both intrinsic and doped system bandgaps decrease with the increase of compression deformation, and the values of the bandgap under the same compression deformation after Cr doping are reduced compared with the corresponding intrinsic states. When the compressive deformation reaches 10%, both the intrinsic and doped system band gaps are close to zero...
April 18, 2024: Journal of Molecular Modeling
https://read.qxmd.com/read/38634929/improving-early-cholecystectomy-rate-in-acute-cholecystitis-with-an-evidence-based-local-multidisciplinary-protocol-and-a-surgical-audit-single-center-experience-through-an-acute-care-surgery-division
#18
JOURNAL ARTICLE
J M Aranda-Nárvaez, P Fernández-Galeano, L Romacho-López, I Cabrera-Serna, A Titos-García, I Mirón-Fernández, J Santoyo-Santoyo
PURPOSE: To analyze if, after implementation of an evidence-based local multidisciplinary protocol for acute cholecystitis (AC), an intermediate surgical audit could improve early cholecystectomy (EC) rate and other therapeutic indicators. METHODS: Longitudinal cohort study at a tertiary center. The local protocol, promoted, created, and periodically revised by the Acute Care Surgery Unit (ACSu) was updated and approved on March 2019. A specific registry was prospectively fulfilled with demographics, comorbidity, type of presentation, diagnostic items, therapeutic decision, and clinical course, considering both non-operative management (NOM) or cholecystectomy, early and delayed (EC and DC)...
April 18, 2024: Langenbeck's Archives of Surgery
https://read.qxmd.com/read/38634859/deep-learning-based-optimization-of-field-geometry-for-total-marrow-irradiation-delivered-with-volumetric-modulated-arc-therapy
#19
JOURNAL ARTICLE
Nicola Lambri, Giorgio Longari, Daniele Loiacono, Ricardo Coimbra Brioso, Leonardo Crespi, Carmela Galdieri, Francesca Lobefalo, Giacomo Reggiori, Roberto Rusconi, Stefano Tomatis, Luisa Bellu, Stefania Bramanti, Elena Clerici, Chiara De Philippis, Damiano Dei, Pierina Navarria, Carmelo Carlo-Stella, Ciro Franzese, Marta Scorsetti, Pietro Mancosu
BACKGROUND: Total marrow (lymphoid) irradiation (TMI/TMLI) is a radiotherapy treatment used to selectively target the bone marrow and lymph nodes in conditioning regimens for allogeneic hematopoietic stem cell transplantation. A complex field geometry is needed to cover the large planning target volume (PTV) of TMI/TMLI with volumetric modulated arc therapy (VMAT). Five isocenters and ten overlapping fields are needed for the upper body, while, for patients with large anatomical conformation, two specific isocenters are placed on the arms...
April 18, 2024: Medical Physics
https://read.qxmd.com/read/38634855/tools-and-methods-for-high-throughput-single-cell-imaging-with-the-mother-machine
#20
JOURNAL ARTICLE
Ryan Thiermann, Michael Sandler, Gursharan Ahir, John T Sauls, Jeremy Schroeder, Steven Brown, Guillaume Le Treut, Fangwei Si, Dongyang Li, Jue D Wang, Suckjoon Jun
Despite much progress, image processing remains a significant bottleneck for high-throughput analysis of microscopy data. One popular platform for single-cell time-lapse imaging is the mother machine, which enables long-term tracking of microbial cells under precisely controlled growth conditions. While several mother machine image analysis pipelines have been developed in the past several years, adoption by a non-expert audience remains a challenge. To fill this gap, we implemented our own software, MM3, as a plugin for the multidimensional image viewer napari...
April 18, 2024: ELife
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