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https://www.readbyqxmd.com/read/29779276/-fabrication-and-accuracy-research-on-3d-printing-dental-model-based-on-cone-beam-computed-tomography-digital-modeling
#1
Hui-Rong Zhang, Le-Feng Yin, Yan-Li Liu, Li-Yi Yan, Ning Wang, Gang Liu, Xiao-Li An, Bin Liu
OBJECTIVE: The aim of this study is to build a digital dental model with cone beam computed tomography (CBCT), to fabricate a virtual model via 3D printing, and to determine the accuracy of 3D printing dental model by comparing the result with a traditional dental cast. METHODS: CBCT of orthodontic patients was obtained to build a digital dental model by using Mimics 10.01 and Geomagic studio software. The 3D virtual models were fabricated via fused deposition modeling technique (FDM)...
April 1, 2018: Hua Xi Kou Qiang Yi Xue za Zhi, Huaxi Kouqiang Yixue Zazhi, West China Journal of Stomatology
https://www.readbyqxmd.com/read/29779218/an-analysis-of-the-timing-and-materials-associated-with-pulp-disease-following-restorative-dental-treatment
#2
J B Yong, S Sivarajan, P V Abbott
AIM: To assess whether the timing of pulp disease after tooth restoration was associated with type of restorative dental material used, extent of the restoration, or tooth type. METHODOLOGY: A comprehensive search and analysis of data using the Titanium Oral Health Management software program at The Oral Health Centre of Western Australia was performed to correlate procedural codes for teeth that had restorations placed and subsequently developed pulp disease requiring endodontic treatment or extraction from 1st January 2009 to 31st December 2013...
May 19, 2018: International Endodontic Journal
https://www.readbyqxmd.com/read/29779197/cardiac-versus-non-cardiac-related-mortality-following-percutaneous-coronary-intervention-in-patients-with-insulin-treated-type-2-diabetes-mellitus-a-meta-analysis
#3
Qiang Wang, Hao Liu, Jiawang Ding
INTRODUCTION: Cardiovascular mortality is a major concern for patients with type 2 diabetes mellitus (T2DM). Insulin therapy significantly contributes to a high rate of death in these patients. We have performed a meta-analysis comparing cardiac and non-cardiac-related mortality following percutaneous coronary intervention (PCI) in a sample of patients with insulin-treated type 2 diabetes mellitus (ITDM). METHODS: Studies were included in the meta-analysis if: (1) they were trials or cohort studies involving patients with T2DM post-PCI; (2) the outcomes in ITDM were separately reported; and (3) they reported cardiac death and non-cardiac death among their clinical endpoints...
May 19, 2018: Diabetes Therapy: Research, Treatment and Education of Diabetes and related Disorders
https://www.readbyqxmd.com/read/29779129/practical-impact-of-a-decision-support-for-goal-directed-fluid-therapy-on-protocol-adherence-a-clinical-implementation-study-in-patients-undergoing-major-abdominal-surgery
#4
Alexandre Joosten, Reda Hafiane, Marco Pustetto, Luc Van Obbergh, Thierry Quackels, Alexis Buggenhout, Jean-Louis Vincent, Brigitte Ickx, Joseph Rinehart
The purpose of this study was to assess the effects of using a real time clinical decision-support system, "Assisted Fluid Management" (AFM), to guide goal-directed fluid therapy (GDFT) during major abdominal surgery. We compared a group of patients managed using the AFM system with a historical cohort of patients (control group) who had been managed using a manual GDFT strategy. Adherence to the protocol was defined as the relative intraoperative time spent with a stroke volume variation (SVV) < 13%...
May 19, 2018: Journal of Clinical Monitoring and Computing
https://www.readbyqxmd.com/read/29778712/validation-reliability-and-specificity-of-clinicom%C3%A2-psychiatric-assessment-software
#5
Nelson Handal, James LePage, Philip Dayley, Barbara Baldwin, Amellia Roeser, Joni Kay, Heather Ann Theobald, Michael Nellamattathil, Scott Drotar, Connor Weir, Neil Tindell, Kevin Tice
The purpose of this study was to determine the specificity and reproducibility of CliniCom™ Psychiatric Assessment Software to appropriately diagnose five prevalent mental health disorders. This online assessment tool incorporates proprietary algorithms for its propensity assessment. Unlike other questionnaires, which require a survey per specific mental disorder, CliniCom can simultaneously assess multiple mental disorders for an individual. CliniCom was concordant with other commonly used assessment tools in diagnosing five prevalent disorders including: Attention Deficit and Hyperactivity Disorder, Generalized Anxiety Disorder, Major Depressive Disorder, Obsessive Compulsive Disorder, and Social Phobia...
May 12, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29778641/subregional-volumes-of-the-hippocampus-in-relation-to-cognitive-function-and-risk-of-dementia
#6
Tavia E Evans, Hieab H H Adams, Silvan Licher, Frank J Wolters, Aad van der Lugt, M Kamran Ikram, Michael J O'Sullivan, Meike W Vernooij, M Arfan Ikram
BACKGROUND: Total hippocampal volume has been consistently linked to cognitive function and dementia. Yet, given its complex and parcellated internal structure, the role of subregions of the hippocampus in cognition and risk of dementia remains relatively underexplored. We studied subregions of the hippocampus in a large population-based cohort to further understand their role in cognitive impairment and dementia risk. METHODS: We studied 5035 dementia- and stroke-free persons from the Rotterdam Study, aged over 45 years...
May 17, 2018: NeuroImage
https://www.readbyqxmd.com/read/29778526/rt-qpcr-analysis-of-human-melanoma-progression-related-genes-a-novel-workflow-for-selection-and-validation-of-candidate-reference-genes
#7
Marcelina E Janik, Sabina Szwed, Paweł Grzmil, Radosław Kaczmarek, Marcin Czerwiński, Dorota Hoja-Łukowicz
The objective of this study was to identify a normalizer or combination of normalizers for quantitative evaluation of the expression of a target gene of interest during melanoma progression. Adult melanocytes, uveal primary melanoma cells and cutaneous primary and metastatic melanoma cells were used to construct a panel of 14 experimental models reflecting cancer promotion and progression. Hypoxanthine phosphoribosyltransferase 1 (HPRT1), glucuronidase beta (GUSB), ribosomal protein S23 (RPS23), phosphoglycerate kinase 1 (PGK1) and small nuclear ribonucleoprotein polypeptide A (SRNPA) were chosen as candidate housekeeping genes...
May 17, 2018: International Journal of Biochemistry & Cell Biology
https://www.readbyqxmd.com/read/29778328/acoustic-perceptual-correlates-of-voice-in-indian-hindu-purohits
#8
Radish Kumar Balasubramanium, Sudhin Karuppali, Gagan Bajaj, Anuradha Shastry, Jayashree Bhat
OBJECTIVE: Purohit, in the Indian religious context (Hindu), means priest. Purohits are professional voice users who use their voice while performing regular worships and rituals in temples and homes. Any deviations in their voice can have an impact on their profession. Hence, there is a need to investigate the voice characteristics of purohits using perceptual and acoustic analyses. METHODS: A total of 44 men in the age range of 18-30 years were divided into two groups...
May 16, 2018: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/29778065/reliability-of-the-sub-components-of-the-instrumented-timed-up-and-go-test-in-ambulatory-children-with-traumatic-brain-injury-and-typically-developed-controls
#9
Mark A Newman, Mark A Hirsch, Richard D Peindl, Nahir A Habet, Tobias J Tsai, Michael S Runyon, Toan Huynh, Nigel Zheng
BACKGROUND: Studies have evaluated the test-re-test reliability of subcomponents of the timed up and-go test in adults by using body-worn inertial sensors. However, studies in children have not been reported in the literature. RESEARCH QUESTION: To evaluate the within-session reliability of subcomponents of a newly developed electronically augmented timed 'upand-go' test (EATUG) in ambulatory children with traumatic brain injury (TBI) and children with typical development (TD)...
May 16, 2018: Gait & Posture
https://www.readbyqxmd.com/read/29777644/closing-the-gap-between-people-and-programs-lessons-from-implementation-of-social-accountability-for-family-planning-and-reproductive-health-in-uganda
#10
Vicky Boydell, Stella Neema, Kelsey Wright, Karen Hardee
Globally, women's access to modern contraception can be attributed to poor service conditions and care. Growing evidence from across the health sector has found that social accountability approaches have the potential to improve the quality of care and therefore the utilization of health services, little of this evidence relates to family planning and reproductive health programs. This paper therefore assessed the results of retrospective implementation research into a five-year social accountability project in Uganda that focused on family planning and reproductive health...
March 2018: African Journal of Reproductive Health
https://www.readbyqxmd.com/read/29777440/mir-27a-b-regulates-liver-regeneration-by-posttranscriptional-modification-of-tmub1
#11
Xiang Lan, Guangyao Li, Hongming Liu, Hangwei Fu, Ping Chen, Menggang Liu
BACKGROUND: Transmembrane and ubiquitin-like domain-containing 1 protein (Tmub1) negatively regulates liver regeneration. However, whether this regulation involves posttranscriptional modification of Tmub1 expression is unknown. AIM: The aim of the study was to investigate whether microRNA (miR)-27a/b regulates posttranscriptional modification of Tmub1 and cell proliferation during liver regeneration. METHODS: Tmub1 mRNA 3'-untranslated region (UTR) sequences were analyzed using online software...
May 17, 2018: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/29777329/population-pharmacokinetics-of-theophylline-in-adult-chinese-patients-with-asthma-and-chronic-obstructive-pulmonary-disease
#12
Yanjiao Ma, Ling Xue, Xin Chen, Yingbo Kang, Yong Wang, Liqing Wang
Background Theophylline has a narrow therapeutic range and large interindividual variability in blood levels, so a thorough understanding of its pharmacokinetic characteristics is essential. Population pharmacokinetic (PPK) approaches could achieve it and many PPK studies of theophylline have been reported in infants. However, none was conducted in Chinese adults and none has explored the effect of CYP1A2 genotypes on the PPK characteristics of theophylline in adults. Objective To evaluate the PPK characteristics of theophylline and to assess the possible influence of covariates, including CYP1A2 genotypes, on theophylline clearance in Chinese adult patients...
May 18, 2018: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/29777325/developing-an-interactive-data-visualization-tool-to-assess-the-impact-of-decision-support-on-clinical-operations
#13
Timothy C Huber, Arun Krishnaraj, Dayna Monaghan, Cree M Gaskin
Due to mandates from recent legislation, clinical decision support (CDS) software is being adopted by radiology practices across the country. This software provides imaging study decision support for referring providers at the point of order entry. CDS systems produce a large volume of data, providing opportunities for research and quality improvement. In order to better visualize and analyze trends in this data, an interactive data visualization dashboard was created using a commercially available data visualization platform...
May 18, 2018: Journal of Digital Imaging: the Official Journal of the Society for Computer Applications in Radiology
https://www.readbyqxmd.com/read/29777324/a-dependable-massive-storage-service-for-medical-imaging
#14
Marco Antonio Núñez-Gaona, Ricardo Marcelín-Jiménez, Josefina Gutiérrez-Martínez, Heriberto Aguirre-Meneses, José Luis Gonzalez-Compean
We present the construction of Babel, a distributed storage system that meets stringent requirements on dependability, availability, and scalability. Together with Babel, we developed an application that uses our system to store medical images. Accordingly, we show the feasibility of our proposal to provide an alternative solution for massive scientific storage and describe the software architecture style that manages the DICOM images life cycle, utilizing Babel like a virtual local storage component for a picture archiving and communication system (PACS-Babel Interface)...
May 18, 2018: Journal of Digital Imaging: the Official Journal of the Society for Computer Applications in Radiology
https://www.readbyqxmd.com/read/29777062/brock-malignancy-risk-calculator-for-pulmonary-nodules-validation-outside-a-lung-cancer-screening-population
#15
Kaman Chung, Onno M Mets, Paul K Gerke, Colin Jacobs, Annemarie M den Harder, Ernst T Scholten, Mathias Prokop, Pim A de Jong, Bram van Ginneken, Cornelia M Schaefer-Prokop
OBJECTIVE: To assess the performance of the Brock malignancy risk model for pulmonary nodules detected in routine clinical setting. METHODS: In two academic centres in the Netherlands, we established a list of patients aged ≥40 years who received a chest CT scan between 2004 and 2012, resulting in 16 850 and 23 454 eligible subjects. Subsequent diagnosis of lung cancer until the end of 2014 was established through linking with the National Cancer Registry...
May 18, 2018: Thorax
https://www.readbyqxmd.com/read/29777016/clinical-utility-of-electronic-alberta-stroke-program-early-computed-tomography-score-software-in-the-enchanted-trial-database
#16
Simon Nagel, Xia Wang, Cheryl Carcel, Thompson Robinson, Richard I Lindley, John Chalmers, Craig S Anderson
BACKGROUND AND PURPOSE: Clinical utility of electronic Alberta Stroke Program Early CT Score (e-ASPECTS), an automated system for quantifying signs of infarction, was evaluated in a large database of thrombolyzed patients with acute ischemic stroke. METHODS: All baseline noncontrast computed tomographic scans of patients with anterior circulation acute ischemic stroke who participated in the alteplase dose arm of the randomized controlled trial ENCHANTED (Enhanced Control of Hypertension and Thrombolysis Stroke Study) were reviewed; poor quality and large (>6 mm) slice thickness were excluded...
May 18, 2018: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/29776916/effect-of-near-infrared-light-therapy-based-on-acupoints-on-the-severity-of-restless-legs-syndrome-in-patients-undergoing-hemodialysis-a-single-blind-randomized-controlled-trial
#17
Mohammad Mehdi Mohammadi, Ali Akbar Vaisi Raygani, Akram Ghobadi, Soheila Samadzadeh, Nader Salari
INTRODUCTION: Restless legs syndrome (RLS) is a common disorder in hemodialysis patients. The present study was conducted to determine the effect of near-infrared (NIR) light therapy given to acupoints on the severity of RLS in patients undergoing hemodialysis. METHODS: This single-blind randomized controlled trial was performed on 60 hemodialysis patients with RLS. Participants who met the inclusion criteria were randomly assigned to an intervention group (n = 30) or a control group (n = 30)...
May 18, 2018: Clinical Medicine & Research
https://www.readbyqxmd.com/read/29776836/analysis-of-incidence-of-traumatic-brain-injury-in-blunt-trauma-patients-with-glasgow-coma-scale-of-12-or-less
#18
Alexander Becker, Kobi Peleg, Oded Olsha, Adi Givon, Boris Kessel
PURPOSE: Early diagnosis of traumatic brain injury (TBI) is important for improving survival and neurologic outcome in trauma victims. The purpose of this study was to assess whether Glasgow Coma Scale (GCS) of 12 or less can predict the presence of TBI and the severity of associated injuries in blunt trauma patients. METHODS: A retrospective cohort study including 303,435 blunt trauma patients who were transferred from the scene to hospital from 1998 to 2013. The data was obtained from the records of the National Trauma Registry maintained by Israel's National Center for Trauma and Emergency Medicine Research, in the Gertner Institute for Epidemiology and Health Policy Research...
April 16, 2018: Chinese Journal of Traumatology, Zhonghua Chuang Shang za Zhi
https://www.readbyqxmd.com/read/29776807/public-health-surveillance-of-multidrug-resistant-clones-of-neisseria-gonorrhoeae-in-europe-a-genomic-survey
#19
Simon R Harris, Michelle J Cole, Gianfranco Spiteri, Leonor Sánchez-Busó, Daniel Golparian, Susanne Jacobsson, Richard Goater, Khalil Abudahab, Corin A Yeats, Beatrice Bercot, Maria José Borrego, Brendan Crowley, Paola Stefanelli, Francesco Tripodo, Raquel Abad, David M Aanensen, Magnus Unemo
BACKGROUND: Traditional methods for molecular epidemiology of Neisseria gonorrhoeae are suboptimal. Whole-genome sequencing (WGS) offers ideal resolution to describe population dynamics and to predict and infer transmission of antimicrobial resistance, and can enhance infection control through linkage with epidemiological data. We used WGS, in conjunction with linked epidemiological and phenotypic data, to describe the gonococcal population in 20 European countries. We aimed to detail changes in phenotypic antimicrobial resistance levels (and the reasons for these changes) and strain distribution (with a focus on antimicrobial resistance strains in risk groups), and to predict antimicrobial resistance from WGS data...
May 15, 2018: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/29776653/accuracy-of-phase-contrast-velocity-mapping-proximal-and-distal-to-stent-artifact-during-cardiac-magnetic-resonance-imaging
#20
Catherine M Avitabile, Matthew A Harris, Ravi S Doddasomayajula, Steven G Chopski, Matthew J Gillespie, Yoav Dori, Andrew C Glatz, Mark A Fogel, Kevin K Whitehead
Little data are available on the accuracy of phase-contrast magnetic resonance imaging (PC-MRI) velocity mapping in the vicinity of intravascular metal stents other than nitinol stents. Therefore, we sought to determine this accuracy using in vitro experiments. An in vitro flow phantom was used with 3 stent types: (1) 316L stainless steel, (2) nitinol self-expanding, and (3) platinum-iridium. Steady and pulsatile flow was delivered with a magnetic resonance imaging-compatible pump (CardioFlow 5000, Shelley Medical, London, Ontario, Canada)...
April 20, 2018: American Journal of Cardiology
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