Stefanie De Smet, Isabell Int-Veen, Gert Vanhollebeke, Matias M Pulopulos, Beatrix Barth, Sarah Pasche, Chris Baeken, Hans-Christoph Nuerk, Christian Plewnia, Vanessa Nieratschker, Andreas Jochen Fallgatter, Ann-Christine Ehlis, Marie-Anne Vanderhasselt, David Rosenbaum
OBJECTIVE: Previous studies suggest that theta burst stimulation (TBS), a form of repetitive transcranial magnetic stimulation (rTMS), applied to the left dorsolateral prefrontal cortex (DLPFC) might be a promising approach to modulate stress-reactive rumination and the associated psychophysiological stress response. Crucially, individuals showing higher levels of trait rumination might benefit more from prefrontal stimulation. METHODS: In this sham-controlled study, 127 healthy individuals, with varying ruminative tendencies, received a single-session of intermittent TBS (iTBS), continuous TBS (cTBS) or sham TBS (sTBS) over the left DLPFC before being confronted with a Trier Social Stress Test...
March 19, 2024: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology