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https://www.readbyqxmd.com/read/28214838/the-role-of-hippocampal-structural-synaptic-plasticity-in-repetitive-transcranial-magnetic-stimulation-to-improve-cognitive-function-in-male-samp8-mice
#1
Jiang Ma, Jinhua Wang, Chaonan Lv, Jingjuan Pang, Bing Han, Mingwei Wang, Yuan Gen
BACKGROUND: Repetitive transcranial magnetic stimulation (rTMS) has been used to improve cognitive function, but the stimulation protocols are variable and the underlying mechanism is unclear. Therefore, we intend to examine whether 5Hz rTMS with 30% maximum output could improve cognitive functions in senescence-accelerated-prone mouse 8 (SAMP8) through changing synaptic plasticity. METHODS: SAMP8 and senescence-accelerated-prone mouse/resistant 1 (SAMR1) (7-month old male) were randomly divided into 3 groups: SMAP8 rTMS group (P8-rTMS), SMAP8 sham-rTMS group (P8-sham), and SAMR1 sham-rTMS group (R1-sham)...
January 18, 2017: Cellular Physiology and Biochemistry
https://www.readbyqxmd.com/read/28208601/surgical-neurostimulation-for-spinal-cord-injury
#2
REVIEW
Aswin Chari, Ian D Hentall, Marios C Papadopoulos, Erlick A C Pereira
Traumatic spinal cord injury (SCI) is a devastating neurological condition characterized by a constellation of symptoms including paralysis, paraesthesia, pain, cardiovascular, bladder, bowel and sexual dysfunction. Current treatment for SCI involves acute resuscitation, aggressive rehabilitation and symptomatic treatment for complications. Despite the progress in scientific understanding, regenerative therapies are lacking. In this review, we outline the current state and future potential of invasive and non-invasive neuromodulation strategies including deep brain stimulation (DBS), spinal cord stimulation (SCS), motor cortex stimulation (MCS), transcutaneous direct current stimulation (tDCS) and repetitive transcranial magnetic stimulation (rTMS) in the context of SCI...
February 10, 2017: Brain Sciences
https://www.readbyqxmd.com/read/28202333/easy-methods-to-make-the-neuronavigated-targeting-of-dlpfc-accurate-and-routinely-accessible-for-rtms
#3
Benjamin Pommier, François Vassal, Claire Boutet, Sophie Jeannin, Roland Peyron, Isabelle Faillenot
OBJECTIVES: Dorsolateral prefrontal cortex (DLPFC) is the main stimulation target for rTMS treatment of depression. DLPFC is located in the middle frontal gyrus and corresponds to the lateral part of Brodmann Areas 9 and 46. Current methods to locate the DLPFC are either based on head landmarks that are inaccurate, or based on MRI-neuronavigation. Neuronavigated-methods are based either on standardized stereotactic coordinates translated to the individual patient or on brain landmarks requiring neuroanatomical skills for their identification...
February 12, 2017: Neurophysiologie Clinique, Clinical Neurophysiology
https://www.readbyqxmd.com/read/28197189/does-a-combined-intervention-program-of-repetitive-transcranial-magnetic-stimulation-and-intensive-occupational-therapy-affect-cognitive-function-in-patients-with-post-stroke-upper-limb-hemiparesis
#4
Takatoshi Hara, Masahiro Abo, Kiyohito Kakita, Takeshi Masuda, Ryunosuke Yamazaki
Low-frequency repetitive transcranial magnetic stimulation (LF-rTMS) to the contralesional hemisphere and intensive occupational therapy (iOT) have been shown to contribute to a significant improvement in upper limb hemiparesis in patients with chronic stroke. However, the effect of the combined intervention program of LF-rTMS and iOT on cognitive function is unknown. We retrospectively investigated whether the combined treatment influence patient's Trail-Making Test part B (TMT-B) performance, which is a group of easy and inexpensive neuropsychological tests that evaluate several cognitive functions...
December 2016: Neural Regeneration Research
https://www.readbyqxmd.com/read/28193533/effect-of-dual-mode-and-dual-site-non-invasive-brain-stimulation-on-freezing-of-gait-in-patients-with-parkinson-s-disease
#5
Won Hyuk Chang, Min Soo Kim, Eunhee Park, Jin Whan Cho, Jinyoung Youn, Yun Kwan Kim, Yun-Hee Kim
OBJECTIVE: To investigate the effect of dual-mode non-invasive brain stimulation (NIBS) with high-frequency repetitive transcranial magnetic stimulation (rTMS) over the primary motor cortex of the lower leg and anodal transcranial direct current stimulation (tDCS) over the left dorsolateral prefrontal cortex compared with rTMS alone in patients with Parkinson's disease (PD) with freezing of gait (FOG). DESIGN: Randomized, double-blind, controlled study. SETTING: Outpatient rehabilitation clinics...
February 10, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28189046/identifying-cortical-first-and-second-language-sites-via-navigated-transcranial-magnetic-stimulation-of-the-left-hemisphere-in-bilinguals
#6
Lorena Tussis, Nico Sollmann, Tobias Boeckh-Behrens, Bernhard Meyer, Sandro M Krieg
The cortical areas that code for the first (L1) and second language (L2) in bilinguals have still not been sufficiently explored. Thus, this study investigated the left-hemispheric distribution of the L1 and L2 using repetitive navigated transcranial magnetic stimulation (rTMS), in combination with an object-naming task, in 10 healthy, right-handed volunteers. In particular, higher error rates (ERs) were observed in the L1, and there was a statistically significant difference between the ERs of L1 and L2 for no-response errors (L1 mean 11...
February 8, 2017: Brain and Language
https://www.readbyqxmd.com/read/28187965/impact-of-rtms-on-functional-connectivity-within-the-language-network-in-schizophrenia-patients-with-auditory-hallucinations
#7
F Briend, E Leroux, N Delcroix, A Razafimandimby, O Etard, S Dollfus
This exploratory study investigated the functional connectivity (FC) in the language network in schizophrenia patients (SZ) with auditory verbal hallucinations (AVHs), and the therapeutic efficacy of rTMS on it. Eleven SZ with AVHs and 10 healthy controls (HC) underwent two fMRI sessions using a speech listening paradigm. SZ received 20Hz rTMS following the first fMRI session. Compared to HC, SZ showed a reduced FC in the language network. While AVHs improved after 12days, no changes in FC were observed. This suggests the efficacy of high-frequency rTMS on AVH without any impact for rTMS on FC within the language network...
February 8, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/28180015/effects-of-intermittent-theta-burst-stimulation-on-manual-dexterity-and-motor-imagery-in-patients-with-multiple-sclerosis-a-quasi-experimental-controlled-study
#8
Mahdieh Azin, Nasser Zangiabadi, Farhad Iranmanesh, Mohammad Reza Baneshi, Seyedshahab Banihashem
BACKGROUND: Intermittent theta burst stimulation (iTBS) is a repetitive transcranial magnetic stimulation (rTMS) protocol that influences cortical excitability and motor function recovery. OBJECTIVES: This study aimed to investigate the effects of iTBS on manual dexterity and hand motor imagery in multiple sclerosis (MS) patients. METHODS: Thirty-six MS patients were non-randomly assigned into sham (control) or iTBS groups. Then, iTBS was delivered to the primary motor cortex for ten days over two consecutive weeks...
October 2016: Iranian Red Crescent Medical Journal
https://www.readbyqxmd.com/read/28167906/non-invasive-mapping-of-face-processing-by-navigated-transcranial-magnetic-stimulation
#9
Stefanie Maurer, Katrin Giglhuber, Nico Sollmann, Anna Kelm, Sebastian Ille, Theresa Hauck, Noriko Tanigawa, Florian Ringel, Tobias Boeckh-Behrens, Bernhard Meyer, Sandro M Krieg
Background: Besides motor and language function, tumor resections within the frontal and parietal lobe have also been reported to cause neuropsychological impairment like prosopagnosia. Objective: Since non-navigated transcranial magnetic stimulation (TMS) has previously been used to map neuropsychological cortical function, this study aims to evaluate the feasibility and spatial discrimination of repetitive navigated TMS (rTMS) mapping for detection of face processing impairment in healthy volunteers. The study was also designed to establish this examination for preoperative mapping in brain tumor patients...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28166475/influence-of-motor-cortex-stimulation-during-motor-training-on-neuroplasticity-as-a-potential-therapeutic-intervention
#10
Crystal L Massie, Caylen White, Katie Pruit, Aubrey Freel, Kaylin Staley, Morgan Backes
Rehabilitation options to promote neuroplasticity may be enhanced when patients are engaged in motor practice during repetitive transcranial magnetic stimulation (rTMS). Twelve participants completed 3 separate sessions: motor practice, motor practice with rTMS, and rTMS only: motor practice consisted of 30 isometric contractions and subthreshold rTMS was 30, 3-s trains at 10 Hz. Assessments included the Box and Block Test (BBT), force steadiness (10% of the maximum voluntary contraction), and TMS (cortical excitability, intracortical inhibition, and intracortical facilitation)...
February 6, 2017: Journal of Motor Behavior
https://www.readbyqxmd.com/read/28161706/the-effect-of-selective-transcranial-magnetic-stimulation-with-functional-near-infrared-spectroscopy-and-intensive-speech-therapy-on-individuals-with-post-stroke-aphasia
#11
Takatoshi Hara, Masahiro Abo, Kiyohito Kakita, Yuko Mori, Makoto Yoshida, Nobuyuki Sasaki
PURPOSE: To examine the efficacy of selective repetitive transcranial magnetic stimulation (rTMS) therapy guided by functional near-infrared spectroscopy (fNIRS) combined with intensive speech therapy (iST) on post-stroke patients with aphasia. MATERIAL AND METHODS: Eight right-handed patients with aphasia in the chronic stage after stroke were grouped into left and right hemisphere-activated for a language task based on pre-intervention fNIRS. Those with left hemisphere activation received 1-Hz TMS to the right inferior frontal gyrus (RtIFG; low-frequency rTMS [LFS] group), and those with right hemisphere activation received 10-Hz TMS to the RtIFG (high-frequency rTMS [HFS] group)...
February 4, 2017: European Neurology
https://www.readbyqxmd.com/read/28161090/repetitive-transcranial-magnetic-stimulation-combined-with-cognitive-training-for-the-treatment-of-alzheimer-s-disease
#12
Jean-Paul Nguyen, Alcira Suarez, Gilles Kemoun, Michel Meignier, Estelle Le Saout, Philippe Damier, Julien Nizard, Jean-Pascal Lefaucheur
OBJECTIVE: To assess the efficacy of a combination of cognitive training (COG) and repetitive transcranial magnetic stimulation (rTMS), on cognitive performance, locomotor activity, apathy, caregiver burden and dependence of patients with Alzheimer's disease (AD). METHODS: A combination of COG and rTMS was performed in 10 patients with AD (NeuroAD procedure) for a period of 5weeks (one session per day, 5days a week), without maintenance sessions. Patients were evaluated at the end of the treatment (D45) and 6months later (M6) by the Mini Mental State Examination (MMSE), the Alzheimer disease assessment scale - cognitive subscale (ADAS-Cog), various neuropsychological tests and clinical scores specific for locomotor activity, apathy, caregiver burden, and dependence, recorded before the study (baseline)...
February 1, 2017: Neurophysiologie Clinique, Clinical Neurophysiology
https://www.readbyqxmd.com/read/28160748/resting-state-eeg-gamma-power-and-theta-gamma-coupling-enhancement-following-high-frequency-left-dorsolateral-prefrontal-rtms-in-patients-with-depression
#13
Yoshihiro Noda, Reza Zomorrodi, Takashi Saeki, Tarek K Rajji, Daniel M Blumberger, Zafiris J Daskalakis, Motoaki Nakamura
OBJECTIVE: We aimed to investigate neuromodulatory effects of high-frequency left dorsolateral prefrontal cortex repetitive transcranial magnetic stimulation (rTMS) on resting-state electroencephalography (EEG) and their clinical and cognitive correlates in patients with depression. METHODS: Thirty-one patients diagnosed with depression included in the present study. Resting-state gamma power and theta-gamma coupling (TGC) were calculated before and after a course of rTMS...
January 9, 2017: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/28157112/dual-mode-noninvasive-brain-stimulation-over-the-bilateral-primary-motor-cortices-in-stroke-patients
#14
Jae Yong Cho, Ahee Lee, Min Su Kim, Eunhee Park, Won Hyuk Chang, Yong-Il Shin, Yun-Hee Kim
BACKGROUND: Noninvasive brain stimulation (NBS) using repetitive transcranial magnetic stimulation (rTMS) or transcranial direct current stimulation (tDCS) has recently been adopted for modulating motor function in stroke patients. OBJECTIVE: We investigated the effect of simultaneous dual-mode stimulation using rTMS and tDCS over the bilateral primary motor cortices (M1) to assess its efficacy as compared to single stimulation using rTMS for the recovery of motor function in subacute stroke patients...
2017: Restorative Neurology and Neuroscience
https://www.readbyqxmd.com/read/28156250/efficacy-of-deep-rtms-for-neuropathic-pain-in-the-lower-limb-a-randomized-double-blind-crossover-trial-of-an-h-coil-and-figure-8-coil
#15
Takeshi Shimizu, Koichi Hosomi, Tomoyuki Maruo, Yuko Goto, Masaru Yokoe, Yu Kageyama, Toshio Shimokawa, Toshiki Yoshimine, Youichi Saitoh
OBJECTIVE Electrical motor cortex stimulation can relieve neuropathic pain (NP), but its use requires patients to undergo an invasive procedure. Repetitive transcranial magnetic stimulation (rTMS) of the primary motor cortex (M1) using a figure-8 coil can relieve NP noninvasively, but its ability to relieve lower limb pain is still limited. Deep rTMS using an H-coil can effectively stimulate deep brain regions and has been widely used for the treatment of various neurological diseases; however, there have been no clinical studies comparing the effectiveness of figure-8 coils and H-coils...
February 3, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/28154905/changes-in-dorsolateral-prefrontal-connectivity-after-rtms-in-treatment-resistant-depression-a-brain-perfusion-spect-study
#16
Raphaëlle Richieri, Damien Jouvenoz, Antoine Verger, Patrick Fiat, Laurent Boyer, Christophe Lançon, Eric Guedj
PURPOSE: Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive and safe alternative to electroconvulsive therapy for treatment-resistant depression (TRD). After rTMS, changes in brain SPECT perfusion have been remotely identified within medial temporal limbic areas, while no local effects have been found within the left dorsolateral prefrontal cortex (DLPFC)-i.e. under the coil. Functional changes in connectivity may underlie these remote effects. Interestingly, functional connectivity has been recently investigated using perfusion SPECT, and abnormalities identified in TRD patients...
February 3, 2017: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/28137412/application-of-noninvasive-brain-stimulation-for-post-stroke-dysphagia-rehabilitation
#17
REVIEW
Zhuo Wang, Wei-Qun Song, Liang Wang
Noninvasive brain stimulation (NIBS), commonly consisting of transcranial magnetic stimulation (TMS), transcranial direct-current stimulation (tDCS), as well as paired associative stimulation (PAS), has attracted increased interest and been applied experimentally in the treatment of post-stroke dysphagia (PSD). This review presented a synopsis of the current research for the application of NIBS on PSD. The intention here was to understand the current research progress and limitations in this field and to stimulate potential research questions not yet investigated for the application of NIBS on patients with PSD...
February 2017: Kaohsiung Journal of Medical Sciences
https://www.readbyqxmd.com/read/28131810/the-effector-independent-nature-of-motor-imagery-evidence-from-rtms-induced-inhibition-to-the-primary-motor-cortices
#18
Sarah N Kraeutner, Tony G J Ingram, Shaun G Boe
Motor imagery (MI), the mental rehearsal of movement, facilitates learning by driving brain activation similar to that of physical practice (PP). However, a growing body of evidence suggests that learning via MI relies more on effector independent as opposed to effector dependent encoding. One approach to probing the nature of MI based learning is to study the primary motor cortex (MC), a brain region known to be critical to effector dependent encoding, but whose involvement in MI is debatable. The current study sought to inform on the nature of MI-based learning by examining the extent to which participants could learn via MI following inhibition of the MC using repetitive transcranial magnetic stimulation (TMS)...
January 25, 2017: Neuropsychologia
https://www.readbyqxmd.com/read/28130194/dynamic-aftereffects-in-supplementary-motor-network-following-inhibitory-transcranial-magnetic-stimulation-protocols
#19
Gong-Jun Ji, Fengqiong Yu, Wei Liao, Kai Wang
The supplementary motor area (SMA) is a key node of the motor network. Inhibitory repetitive transcranial magnetic stimulation (rTMS) of the SMA can potentially improve movement disorders. However, the aftereffects of inhibitory rTMS on brain function remain largely unknown. Using a single-blind, crossover within-subject design, we investigated the role of aftereffects with two inhibitory rTMS protocols [1800 pulses of either 1-Hz repetitive stimulation or continuous theta burst stimulation (cTBS)] on the left SMA...
January 24, 2017: NeuroImage
https://www.readbyqxmd.com/read/28122198/primary-motor-cortex-functionally-contributes-to-language-comprehension-an-online-rtms-study
#20
Nikola Vukovic, Matteo Feurra, Anna Shpektor, Andriy Myachykov, Yury Shtyrov
Among various questions pertinent to grounding human cognitive functions in a neurobiological substrate, the association between language and motor brain structures is a particularly debated one in neuroscience and psychology. While many studies support a broadly distributed model of language and semantics grounded, among other things, in the general modality-specific systems, theories disagree as to whether motor and sensory cortex activity observed during language processing is functional or epiphenomenal...
February 2017: Neuropsychologia
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