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https://www.readbyqxmd.com/read/28086851/efficacy-of-intermittent-theta-burst-stimulation-itbs-and-10-hz-high-frequency-repetitive-transcranial-magnetic-stimulation-rtms-in-treatment-resistant-unipolar-depression-study-protocol-for-a-randomised-controlled-trial
#1
Samuel Bulteau, Veronique Sébille, Guillemette Fayet, Veronique Thomas-Ollivier, Thibault Deschamps, Annabelle Bonnin-Rivalland, Edouard Laforgue, Anne Pichot, Pierre Valrivière, Elisabeth Auffray-Calvier, June Fortin, Yann Péréon, Jean-Marie Vanelle, Anne Sauvaget
BACKGROUND: The treatment of depression remains a challenge since at least 40% of patients do not respond to initial antidepressant therapy and 20% present chronic symptoms (more than 2 years despite standard treatment administered correctly). Repetitive transcranial magnetic stimulation (rTMS) is an effective adjuvant therapy but still not ideal. Intermittent Theta Burst Stimulation (iTBS), which has only been used recently in clinical practice, could have a faster and more intense effect compared to conventional protocols, including 10-Hz high-frequency rTMS (HF-rTMS)...
January 13, 2017: Trials
https://www.readbyqxmd.com/read/28080973/changes-in-interoceptive-processes-following-brain-stimulation
#2
Olga Pollatos, Beate M Herbert, Sandra Mai, Thomas Kammer
The processing and perception of individual internal bodily signals (interoception) has been differentiated to comprise different levels and processes involved. The so-called heartbeat-evoked potential (HEP) offers an additional possibility to examine automatic processing of cardiac signals. Knowledge on neural structures potentially supporting different facets of interoception is still sparse. One way to get insights into neuroanatomical function is to manipulate the activity of different brain structures...
November 19, 2016: Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences
https://www.readbyqxmd.com/read/28076639/transcranial-magnetic-stimulation-for-treatment-of-major-depression-during-pregnancy-a-review
#3
Renata de Melo Felipe, Ygor Arzeno Ferrão
Introduction: Pregnancy is characterized by a high prevalence of mental disorders. Depression is the most common of these disorders and it is a risk factor for negative maternal and child development outcomes. Psychotherapy and pharmacotherapy are conventional and well-established therapeutic options, but some clients fail to respond and the safety of using some pharmacological agents during pregnancy is unclear. Some neuromodulation techniques, such as repetitive transcranial magnetic stimulation (rTMS), have been studied in depressed pregnant women...
October 2016: Trends in Psychiatry and Psychotherapy
https://www.readbyqxmd.com/read/28072907/symptomatic-treatments-for-amyotrophic-lateral-sclerosis-motor-neuron-disease
#4
REVIEW
Louisa Ng, Fary Khan, Carolyn A Young, Mary Galea
BACKGROUND: Motor neuron disease (MND), which is also known as amyotrophic lateral sclerosis (ALS), causes a wide range of symptoms but the evidence base for the effectiveness of the symptomatic treatment therapies is limited. OBJECTIVES: To summarise the evidence from Cochrane Systematic Reviews of all symptomatic treatments for MND. METHODS: We searched the Cochrane Database of Systematic Reviews (CDSR) on 15 November 2016 for systematic reviews of symptomatic treatments for MND...
January 10, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28072660/two-versus-one-high-frequency-repetitive-transcranial-magnetic-stimulation-session-per-day-for-treatment-resistant-depression-a-randomized-sham-controlled-trial
#5
Christos Theleritis, Pavlos Sakkas, Thomas Paparrigopoulos, Silia Vitoratou, Chara Tzavara, Stefania Bonaccorso, Antonios Politis, Constantin R Soldatos, Costantin Psarros
OBJECTIVES: High-frequency repetitive transcranial magnetic stimulation (HF-rTMS) has proven antidepressant effects, but the optimal frequency of sessions remains unclear. METHODS: We conducted a 3-week, sham-controlled trial to assess the antidepressant efficacy of 1 active HF-rTMS session per day (A1 group) compared with 2 per day (A2 group) and equivalent sham sessions (once a day, S1 group; twice a day, S2 group) in patients with treatment-resistant major depression with a subsequent 2-week follow-up period...
January 9, 2017: Journal of ECT
https://www.readbyqxmd.com/read/28069544/left-posterior-inferior-frontal-gyrus-is-causally-involved-in-reordering-during-sentence-processing
#6
Philipp Kuhnke, Lars Meyer, Angela D Friederici, Gesa Hartwigsen
Storage and reordering of incoming information are two core processes required for successful sentence comprehension. Storage is necessary whenever the verb and its arguments (i.e., subject and object) are separated over a long distance, while reordering is necessary whenever the argument order is atypical (e.g., object-first order in German, where subject-first order is typical). Previous neuroimaging work has associated storage with the left planum temporale (PT), and reordering with the left posterior inferior frontal gyrus (pIFG)...
January 6, 2017: NeuroImage
https://www.readbyqxmd.com/read/28068305/comparison-of-treatment-outcomes-following-either-prefrontal-cortical-only-or-dual-site-repetitive-transcranial-magnetic-stimulation-in-chronic-tinnitus-patients-a-double-blind-randomized-study
#7
Tae-Soo Noh, Jeong Sug Kyong, Mun Young Chang, Moo-Kyun Park, Jun-Ho Lee, Seung-Ha Oh, June Sic Kim, Chun Kee Chung, Myung-Whan Suh
OBJECTIVES: We evaluated treatment outcomes following single-site repetitive transcranial magnetic stimulation (rTMS) in the dorsolateral prefrontal cortex (DLPFC) and dual-site rTMS in the auditory cortex (AC) and DLPFC (AC + FC). STUDY DESIGN AND PATIENTS: This prospective randomized double-blind trial initially included 19 patients with chronic tinnitus and 17 of these patients received rTMS on the left AC and left DLPFC or only the left DLPFC. The subjects were randomly allocated to either the dual-site rTMS (AC + FC) protocol (Group 1, n = 9) or the singlesite rTMS (DLPFC) protocol (Group 2, n = 8)...
February 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28062252/using-neuroimaging-to-individualize-tms-treatment-for-depression-toward-a-new-paradigm-for-imaging-guided-intervention
#8
Bruce M Luber, Simon Davis, Elisabeth Bernhardt, Andrada Neacsiu, Lori Kwapil, Sarah H Lisanby, Timothy J Strauman
The standard clinical technique for using repetitive transcranial magnetic stimulation (rTMS) for major depressive disorder (MDD) is associated with limited efficacy to date. Such limited efficacy may be due to reliance on scalp-based targeting rather than state-of-the-science methods which incorporate fMRI-guided neuronavigation based on a specific model of neurocircuit dysfunction. In this review, we examine such a specific model drawn from regulatory focus theory, which postulates two brain/behavior systems, the promotion and prevention systems, underlying goal pursuit...
January 3, 2017: NeuroImage
https://www.readbyqxmd.com/read/28059800/twist-and-turn-into-chronic-disorders-of%C3%A2-consciousness-potential-role-of%C3%A2-the%C3%A2-auditory-stapedial-reflex
#9
Antonino Naro, Rocco Bruno, Antonino Leo, Margherita Russo, Carlo Salviera, Alessia Bramanti, Placido Bramanti, Rocco Salvatore Calabrò
BACKGROUND: Patients suffering from chronic disorders of consciousness (DOC), including minimally conscious state (MCS) and unresponsive wakefulness syndrome (UWS), typically show an awareness impairment paralleled by a significant reflex hyper-excitability, which depend on the cortical deafferentation following brain-damage-induced thalamocortical system deterioration. Nonetheless, recent studies have shown a residual preservation of cortico-subcortical pathways that may sustain residual fragments of awareness in some DOC patients...
January 3, 2017: Restorative Neurology and Neuroscience
https://www.readbyqxmd.com/read/28057451/the-critical-role-of-the-dorsal-fronto-median-cortex-in-voluntary-action-inhibition-a-tms-study
#10
Stefania C Ficarella, Lorella Battelli
BACKGROUND: Action inhibition is a complex decision process that can be triggered by external factors (exogenous) or internal decisions (endogenous). While the neuronal underpinnings of exogenous action inhibition have been extensively investigated, less is known about the brain areas responsible for endogenous action inhibition. OBJECTIVE: We used inhibitory repetitive transcranial magnetic stimulation (rTMS) to test the causal role of two brain areas, the left dorsal fronto-median Cortex (dFMC) and the right Inferior Frontal Cortex (rIFC) in exogenous and endogenous action inhibition...
December 19, 2016: Brain Stimulation
https://www.readbyqxmd.com/read/28049085/high-frequency-repetitive-transcranial-magnetic-stimulation-over-the-left-dlpfc-for-major-depression-session-dependent-efficacy-a-meta-analysis
#11
S Teng, Z Guo, H Peng, G Xing, H Chen, B He, M A McClure, Q Mu
BACKGROUND: Depression is a major debilitating psychiatric disorder. Current antidepressant drugs are often associated with side effects or treatment resistance. The aim of this meta-analysis was to evaluate therapeutic effects of high-frequency repetitive transcranial magnetic stimulation (HF-rTMS) in major depression (MD). METHODS: The medical data bases of PubMed, Medline, Embase and Cochrane Central Register were searched for randomized controlled trials (RCTs) reporting the therapeutic effects of high-frequency rTMS for depression, which were published in English between January 1990 and June 2016...
December 30, 2016: European Psychiatry: the Journal of the Association of European Psychiatrists
https://www.readbyqxmd.com/read/28049084/a-single-session-of-repetitive-transcranial-magnetic-stimulation-of-the-prefrontal-cortex-reduces-cue-induced-craving-in-patients-with-gambling-disorder
#12
A Gay, C Boutet, T Sigaud, A Kamgoue, J Sevos, J Brunelin, C Massoubre
BACKGROUND: Gambling disorder (GD) is common and disabling addictive disorder. In patients with substance use disorders, the application of repetitive transcranial magnetic stimulation (rTMS) over the dorsolateral prefrontal cortex (DLPFC) offers promise to alleviate craving. We hypothesized that applying real compared to sham rTMS over the left DLPFC would reduce gambling craving in patients with GD. METHODS: In a randomized sham-controlled crossover design, 22 treatment-seeking patients with GD received real or sham treatment with high frequency rTMS over the left DLPFC followed a week later by the other type of treatment...
December 30, 2016: European Psychiatry: the Journal of the Association of European Psychiatrists
https://www.readbyqxmd.com/read/28035869/comparative-efficacy-and-tolerability-of-pharmacological-and-somatic-interventions-in-adult-patients-with-treatment-resistant-depression-a-systematic-review-and-network-meta-analysis
#13
Katerina Papadimitropoulou, Carla Vossen, Andreas Karabis, Christina Donatti, Nicole Kubitz
OBJECTIVE: Major depressive disorder (MDD) affects about 10-15% of the general population in a lifetime. A considerable number of patients fail to achieve full symptom remission despite adequate treatment and are considered treatment-resistant (TRD). The current study compared the relative efficacy and tolerability of pharmacological and somatic TRD interventions by means of a Bayesian network meta-analysis. RESEARCH DESIGN AND METHODS: An electronic literature search of MEDLINE, MEDLINE In-Process, EMBASE, PsycInfo, EconLit and Cochrane Library databases for trial published between September 2003 and September 2014 was conducted...
December 30, 2016: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/28034601/the-involvement-of-the-dorsal-stream-in-processing-implied-actions-between-paired-objects-a-tms-study
#14
Shan Xu, Glyn W Humphreys, Carmel Mevorach, Dietmar Heinke
Perceiving and selecting the action possibilities (affordances) provided by objects is an important challenge to human vision, and is not limited to single-object scenarios. Xu et al. (2015) identified two effects of implied actions between paired objects on response selection: an inhibitory effect on responses aligned with the passive object in the pair (e.g. a bowl) and an advantage associated with responses aligned with the active objects (e.g. a spoon). The present study investigated the neurocognitive mechanisms behind these effects by examining the involvement of the ventral (vision for perception) and the dorsal (vision for action) visual streams, as defined in Goodale and Milner's (1992) two visual stream theory...
December 27, 2016: Neuropsychologia
https://www.readbyqxmd.com/read/28034451/predictors-of-response-to-repetitive-transcranial-magnetic-stimulation-rtms-in-the-treatment-of-major-depressive-disorder
#15
G Beuzon, Q Timour, M Saoud
Repetitive transcranial magnetic stimulation (rTMS), based on the principle of electromagnetic induction, consists of applying series of magnetic impulses to the cerebral cortex so as to modulate neurone activity in a target zone. This technique, still experimental, could prove promising in the field of psychiatry, in particular for the treatment of major depressive disorder. It is important for the clinician to be able to assess the response potential of a given patient to rTMS, and this among other things requires relevant predictive factors to be available...
December 26, 2016: L'Encéphale
https://www.readbyqxmd.com/read/28030740/repetitive-transcranial-magnetic-stimulation-for-the-acute-treatment-of-major-depressive-episodes-a-systematic-review-with-network-meta-analysis
#16
Andre R Brunoni, Anna Chaimani, Adriano H Moffa, Lais B Razza, Wagner F Gattaz, Zafiris J Daskalakis, Andre F Carvalho
Importance: Although several strategies of repetitive transcranial magnetic stimulation (rTMS) have been investigated as treatment of major depressive disorder (MDD), their comparative efficacy and acceptability is unknown. Objective: To establish the relative efficacy and acceptability of the different modalities of rTMS used for MDD by performing a network meta-analysis, obtaining a clinically meaningful treatment hierarchy. Data Sources: PubMed/MEDLINE, EMBASE, PsycInfo, and Web of Science were searched up until October 1, 2016...
December 28, 2016: JAMA Psychiatry
https://www.readbyqxmd.com/read/28008080/repetitive-transcranial-magnetic-stimulation-modulates-the-impact-of-a-negative-mood-induction
#17
Martin Möbius, Lylis Lacomblé, Thomas Meyer, Dennis J L G Schutter, Tom Gielkens, Eni S Becker, Indira Tendolkar, Philip van Eijndhoven
High frequency repetitive Transcranial Magnetic Stimulation (rTMS) over the left dorsolateral prefrontal cortex (DLPFC) has been found to alleviate depressive symptoms. However, the mechanisms driving these effects are still poorly understood. In the current study, we tested the idea that this intervention protects against negative mood shifts following emotional provocation. We furthermore explored changes in EEG activity (frontal alpha asymmetry) and effects on attentional processing (emotional Stroop). To this end, 23 healthy individuals participated in two sessions separated by one week, whereby they once received 15 min of 10Hz rTMS stimulation (1500 pulses) at 110% of the individual motor threshold, and once sham stimulation...
December 21, 2016: Social Cognitive and Affective Neuroscience
https://www.readbyqxmd.com/read/27994543/repetitive-tms-on-left-cerebellum-affects-impulsivity-in-borderline-personality-disorder-a-pilot-study
#18
Giulia Zelda De Vidovich, Riccardo Muffatti, Jessica Monaco, Nicoletta Caramia, Davide Broglia, Edgardo Caverzasi, Francesco Barale, Egidio D'Angelo
The borderline personality disorder (BPD) is characterized by a severe pattern of instability in emotional regulation, interpersonal relationships, identity and impulse control. These functions are related to the prefrontal cortex (PFC), and since PFC shows a rich anatomical connectivity with the cerebellum, the functionality of the cerebellar-PFC axis may impact on BPD. In this study, we investigated the potential involvement of cerebello-thalamo-cortical connections in impulsive reactions through a pre/post stimulation design...
2016: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/27993562/superior-parietal-cortex-and-the-attention-to-delayed-intention-an-rtms-study
#19
Giorgia Cona, Giuliana Marino, Patrizia Silvia Bisiacchi
Prospective memory (PM) is the ability to remember to carry out an intention when the appropriate cue occurs. This study aimed to investigate whether the superior parietal cortex is causally involved in PM and, if so, what is its functional role. We applied repetitive transcranial magnetic stimulation (rTMS) to the left and right superior parietal cortex, and we evaluated the TMS effects on two different PM tasks that required to direct the attention towards either the external stimuli ('Monitoring-load' task) or the intention in memory ('Retrospective-load' task)...
December 16, 2016: Neuropsychologia
https://www.readbyqxmd.com/read/27991181/the-pivotal-role-of-the-right-parietal-lobe-in-temporal-attention
#20
Sara Agosta, Denise Magnago, Sarah Tyler, Emily Grossman, Emanuela Galante, Francesco Ferraro, Nunzia Mazzini, Gabriele Miceli, Lorella Battelli
The visual system is extremely efficient at detecting events across time even at very fast presentation rates; however, discriminating the identity of those events is much slower and requires attention over time, a mechanism with a much coarser resolution [Cavanagh, P., Battelli, L., & Holcombe, A. O. Dynamic attention. In A. C. Nobre & S. Kastner (Eds.), The Oxford handbook of attention (pp. 652-675). Oxford: Oxford University Press, 2013]. Patients affected by right parietal lesion, including the TPJ, are severely impaired in discriminating events across time in both visual fields [Battelli, L...
December 19, 2016: Journal of Cognitive Neuroscience
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