keyword
MENU ▼
Read by QxMD icon Read
search

Evoked potentials

keyword
https://www.readbyqxmd.com/read/29044528/endomorphins-potentiate-asic-currents-and-enhance-the-lactic-acid-mediated-increase-in-arterial-blood-pressure-effects-amplified-in-hindlimb-ischemia
#1
Mohamed Farrag, Julie K Drobish, Henry L Puhl, Joyce S Kim, Paul B Herold, Marc P Kaufman, Victor Ruiz-Velasco
Chronic muscle ischemia leads to accumulation of lactic acid and other inflammatory mediators with a subsequent drop in interstitial pH. Acid-sensing ion channels (ASICs), expressed in thin muscle afferents, sense the decrease in pH and evoke a pressor reflex known to increase mean arterial pressure. The naturally occurring endomorphins are also released by primary afferents under ischemic conditions. We examined whether high affinity mu opioid receptor (MOR) agonists, endomorphin-1 (E-1) and -2 (E-2), modulate ASIC currents and the lactic acid-mediated pressor reflex...
October 16, 2017: Journal of Physiology
https://www.readbyqxmd.com/read/29043038/habitat-niche-breadth-predicts-invasiveness-in-solitary-ascidians
#2
Itai Granot, Noa Shenkar, Jonathan Belmaker
A major focus of invasion biology is understanding the traits associated with introduction success. Most studies assess these traits in the invaded region, while only few compare nonindigenous species to the pool of potential invaders in their native region. We focused on the niche breadth hypothesis, commonly evoked but seldom tested, which states that generalist species are more likely to become introduced as they are capable of thriving under a wide set of conditions. Based on the massive introduction of tropical species into the Mediterranean via the Suez Canal (Lessepsian migration), we defined ascidians in the Red Sea as the pool of potential invaders...
October 2017: Ecology and Evolution
https://www.readbyqxmd.com/read/29042004/quantitative-functional-mri-and-neurophysiological-markers-in-a-case-of-gerstmann-str%C3%A3-ussler-scheinker-syndrome
#3
Silvia Marino, Rosa Morabito, S De Salvo, L Bonanno, A Bramanti, P Pollicino, R Giorgianni, Placido Bramanti
Gerstmann-Sträussler-Scheinker syndrome (GSS) is an inherited autosomal dominant prion disease, caused by a codon 102 proline to leucine substitution (P102L) in the prion protein gene (PRNP). We describe the case of a 40-year-old male, affected by a slowly progressive gait disturbance, leg weakness and cognitive impairment. Genomic DNA revealed a point mutation of PRNP at codon 102, resulting in P102L, and the diagnosis of GSS was confirmed. Somatosensory evoked potentials showed alterations of principal parameters, particularly in the right upper and lower limbs...
July 2017: Functional Neurology
https://www.readbyqxmd.com/read/29041870/fluid-biomarker-and-electrophysiological-outcome-measures-for-progressive-ms-trials
#4
Christian Barro, Letizia Leocani, David Leppert, Giancarlo Comi, Ludwig Kappos, Jens Kuhle
Progressive multiple sclerosis (MS) is characterized by insidious clinical worsening that is difficult to accurately quantify and predict. Biofluid markers and electrophysiological measures are potential candidate outcome measures in clinical trials, allowing the quantification of nervous damage occurring in the disease. Neurofilaments are highly specific neuronal proteins. They may have come closest to such applications by their higher concentrations repeatedly demonstrated in cerebrospinal fluid (CSF) in all stages of MS, during relapses, their responsiveness to disease-modifying treatments in relapsing and progressive MS and their associations with measures of inflammatory and degenerative magnetic resonance imaging (MRI) outcomes...
October 2017: Multiple Sclerosis: Clinical and Laboratory Research
https://www.readbyqxmd.com/read/29040750/cool-callous-and-in-control-superior-inhibitory-control-in-frequent-players-of-video-games-with-violent-content
#5
Laura Stockdale, Robert G Morrison, Robert Palumbo, James Garbarino, Rebecca L Silton
Research on the effects of media violence exposure has shown robust associations among violent media exposure, increased aggressive behavior, and decreased empathy. Preliminary research indicates that frequent players of violent video games may have differences in emotional and cognitive processes compared to infrequent or non-players, yet research examining the amount and content of game play and the relation of these factors with affective and cognitive outcomes is limited. The present study measured neural correlates of response inhibition in the context of implicit attention to emotion, and how these factors are related to empathic responding in frequent and infrequent players of video games with graphically violent content...
October 4, 2017: Social Cognitive and Affective Neuroscience
https://www.readbyqxmd.com/read/29039494/internal-driving-factors-leading-to-extrahepatic-manifestation-of-the-hepatitis%C3%A2-c-virus-infection
#6
Zhou-Yi Wu, Jian-Rui Li, Meng-Hao Huang, Jun-Jun Cheng, Hu Li, Jin-Hua Chen, Xiao-Qin Lv, Zong-Gen Peng, Jian-Dong Jiang
The hepatitis C virus (HCV) infection is associated with various extrahepatic manifestations, which are correlated with poor outcomes, and thus increase the morbidity and mortality of chronic hepatitis C (CHC). Therefore, understanding the internal linkages between systemic manifestations and HCV infection is helpful for treatment of CHC. Yet, the mechanism by which the virus evokes the systemic diseases remains to be elucidated. In the present study, using gene set enrichment analysis (GSEA) and signaling pathway impact analysis (SPIA), a comprehensive analysis of microarray data of mRNAs was conducted in HCV-infected and -uninfected Huh7...
October 5, 2017: International Journal of Molecular Medicine
https://www.readbyqxmd.com/read/29038847/touching-lips-and-hearing-fingers-effector-specific-congruency-between-tactile-and-auditory-stimulation-modulates-n1-amplitude-and-alpha-desynchronization
#7
Guannan Shen, Andrew N Meltzoff, Peter J Marshall
Understanding the interactions between audition and sensorimotor processes is of theoretical importance, particularly in relation to speech processing. Although one current focus in this area is on interactions between auditory perception and the motor system, there has been less research on connections between the auditory and somatosensory modalities. The current study takes a novel approach to this omission by examining specific auditory-tactile interactions in the context of speech and non-speech sound production...
October 16, 2017: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://www.readbyqxmd.com/read/29038666/study-of-methylene-blue-ototoxicity-in-the-guinea-pig
#8
Sarah Belhassen, Musaed Alzahrani, Marc-Elie Nader, Louis Gaboury, Issam Saliba
BACKGROUND: Methylene blue is widely used in the medical field, especially as a blue dye for staining. It is also used as a photosensitizing agent in antimicrobial photodynamic therapy, which once photoactivated is effective for the eradication of several multi-resistant bacteria. The objective of this study was to investigate the ototoxic potential of methylene blue and precise its use in otology. METHODS: It was a prospective animal study performed on guinea pigs in our tertiary medical center...
November 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/29037596/attenuated-chemosensory-responsiveness-of-the-grueneberg-ganglion-in-mouse-pups-at-warm-temperatures
#9
Rosolino Bumbalo, Marilena Lieber, Esther Lehmann, Ines Wolf, Heinz Breer, Joerg Fleischer
Neurons of the Grueneberg ganglion (GG) in the anterior nasal region of mice respond to a small set of odorous compounds, including given dimethylpyrazines present in mouse urine. Consequently, mouse pups living in murine colonies are presumably commonly exposed to such GG-activating substances. Since stimulation of the GG elicits alarm and stress reactions in mice, the question arises whether such a GG activation potentially inducing stress could be reduced when pups might rather feel secure in the presence of their mother...
October 13, 2017: Neuroscience
https://www.readbyqxmd.com/read/29037259/immuno-thermal-ablations-boosting-the-anticancer-immune-response
#10
REVIEW
Ryan Slovak, Johannes M Ludwig, Scott N Gettinger, Roy S Herbst, Hyun S Kim
The use of immunomodulation to treat malignancies has seen a recent explosion in interest. The therapeutic appeal of these treatments is far reaching, and many new applications continue to evolve. In particular, immune modulating drugs have the potential to enhance the systemic anticancer immune effects induced by locoregional thermal ablation. The immune responses induced by ablation monotherapy are well documented, but independently they tend to be incapable of evoking a robust antitumor response. By adding immunomodulators to traditional ablative techniques, several researchers have sought to amplify the induced immune response and trigger systemic antitumor activity...
October 17, 2017: Journal for Immunotherapy of Cancer
https://www.readbyqxmd.com/read/29036851/a-novel-low-cost-approach-for-navigated-transcranial-magnetic-stimulation
#11
Jakob Rodseth, Edward P Washabaugh, Chandramouli Krishnan
BACKGROUND: Transcranial magnetic stimulation (TMS) is commonly used for assessing or modulating brain excitability. However, the credibility of TMS outcomes depends on accurate and reliable coil placement during stimulation. Navigated TMS systems can address this issue, but these systems are expensive for routine use in clinical and research environments. OBJECTIVE: The purpose of this study was to provide a high-quality open source framework for navigated TMS and test its reliability and accuracy using standard TMS procedures...
October 9, 2017: Restorative Neurology and Neuroscience
https://www.readbyqxmd.com/read/29036454/mirror-and-absence-of-counter-mirror-responses-to-action-sounds-measured-with-tms
#12
Luca F Ticini, Simone Schütz-Bosbach, Florian Waszak
To what extent is the mirror neuron mechanism malleable to experience? The answer to this question can help characterising its ontogeny and its role in social cognition. Some suggest that it develops through sensorimotor associations congruent with our own actions. Others argue for its extreme volatility that will encode any sensorimotor association in the environment. Here, we added to this debate by exploring the effects of short goal-directed "mirror" and "counter-mirror" trainings (a "mirror" training is defined as the first type of training encountered by the participants) on human auditory mirror motor-evoked potentials (MEPs)...
September 22, 2017: Social Cognitive and Affective Neuroscience
https://www.readbyqxmd.com/read/29035887/valeriana-officinalis-root-extract-modulates-cortical-excitatory-circuits-in-humans
#13
Ludovico Mineo, Carmen Concerto, Dhaval Patel, Tyrone Mayorga, Michael Paula, Eileen Chusid, Eugenio Aguglia, Fortunato Battaglia
BACKGROUND: Valeriana officinalis extract (VE) is a popular herbal medicine used for the treatment of anxiety and sleep disorders. Although the anxiolytic and sedative effects are mainly attributed to the modulation of GABA-ergic transmission, the mechanism of action has not been fully investigated in humans. Noninvasive brain stimulation protocols can be used to elucidate the mechanisms of action of psychoactive substances at the cortical level in humans. In this study, we investigated the effects of a single dose of VE on cortical excitability as assessed with transcranial magnetic stimulation (TMS)...
October 17, 2017: Neuropsychobiology
https://www.readbyqxmd.com/read/29035822/intraoperative-direct-cortical-stimulation-motor-evoked-potentials-stimulus-parameter-recommendations-based-on-rheobase-and-chronaxie
#14
Tariq M Abalkhail, David B MacDonald, Ibrahim AlThubaiti, Faisal A AlOtaibi, Bent Stigsby, Amal A Mokeem, Iftetah A AlHamoud, Maher I Hassounah, Salah M Baz, Abdulaziz AlSemari, Hesham M AlDhalaan, Sameena Khan
OBJECTIVE: To determine optimal interstimulus interval (ISI) and pulse duration (D) for direct cortical stimulation (DCS) motor evoked potentials (MEPs) based on rheobase and chronaxie derived with two techniques. METHODS: In 20 patients under propofol/remifentanil anesthesia, 5-pulse DCS thenar MEP rheobase and chronaxie with 2, 3, 4 and 5ms ISI were measured by linear regression of five charge thresholds at 0.05, 0.1, 0.2, 0.5 and 1msD, and estimated from two charge thresholds at 0...
September 28, 2017: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/29035687/acute-glutamine-ingestion-modulates-lymphocytic-responses-to-exhaustive-exercise-in-the-heat
#15
Chen Zheng, Xiang-Ke Chen, Yue Zhou
The purpose of this study was to determine if acute intake of glutamine modulates homeostatic, hematologic, immune, and inflammatory responses to exhaustive exercise in the heat. Thirteen healthy untrained young men participated in this randomized, double-blind, placebo-controlled, crossover study. They served as their own control and completed two trials of treadmill exercise at 40% VO2max to exhaustion in a hot environment (38.0 ± 1.0 °C, 60.0 ± 5.0 % relative humidity, and 20.8% oxygen) following placebo (PLA) and glutamine (GLN) consumption...
October 16, 2017: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/29035204/four-novel-motion-paradigms-based-on-steady-state-motion-visual-evoked-potential
#16
Wenqiang Yan, Guanghua Xu, Jun Xie, Min Li, Ziyan Dan
OBJECTIVE: The purpose of this work was to study the applicability of paradigms with motion forms for use in a brain-computer interface (BCI). We examined the performances of different paradigms and evaluated the stimulus effects. METHODS: We designed four novel stimulus paradigms based on basic motion modes: swing, rotation, spiral, and radial contraction-expansion. Canonical correlation analysis (CCA) was used to analyze the accuracy. Additionally, we optimized CCA template signal harmonic combinations for the different motion paradigms...
October 13, 2017: IEEE Transactions on Bio-medical Engineering
https://www.readbyqxmd.com/read/29034483/effect-of-sensory-and-motor-connectivity-on-hand-function-in-pediatric-hemiplegia
#17
Disha Gupta, Alexandre Barachant, Andrew M Gordon, Claudio Ferre, Hsing-Ching Kuo, Jason B Carmel, Kathleen M Friel
OBJECTIVE: We tested the hypothesis that somatosensory system injury would more strongly affect movement than motor system injury in children with unilateral cerebral palsy (USCP). This hypothesis was based on how somatosensory and corticospinal circuits adapt to injury during development: while the motor system can maintain connections to the impaired hand from the uninjured hemisphere, this doesn't occur in the somatosensory system. As a corollary, cortical injury strongly impairs sensory function, so we hypothesized that cortical lesions would impair hand function more than subcortical lesions...
October 16, 2017: Annals of Neurology
https://www.readbyqxmd.com/read/29033795/cellular-mechanisms-of-cortisol-induced-changes-in-mauthner-cell-excitability-in-the-startle-circuit-of-goldfish
#18
Daniel R Bronson, Thomas Preuss
Predator pressure and olfactory cues (alarm substance) have been shown to modulate Mauthner cell (M-cell) initiated startle escape responses (C-starts) in teleost fish. The regulation of such adaptive responses to potential threats is thought to involve the release of steroid hormones such as cortisol. However, the mechanism by which cortisol may regulate M-cell excitability is not known. Here, we used intrasomatic, in vivo recordings to elucidate the acute effects of cortisol on M-cell membrane properties and sound evoked post-synaptic potentials (PSPs)...
2017: Frontiers in Neural Circuits
https://www.readbyqxmd.com/read/29033792/spontaneous-and-evoked-activity-from-murine-ventral-horn-cultures-on-microelectrode-arrays
#19
Bryan J Black, Rahul Atmaramani, Joseph J Pancrazio
Motor neurons are the site of action for several neurological disorders and paralytic toxins, with cell bodies located in the ventral horn (VH) of the spinal cord along with interneurons and support cells. Microelectrode arrays (MEAs) have emerged as a high content assay platform for mechanistic studies and drug discovery. Here, we explored the spontaneous and evoked electrical activity of VH cultures derived from embryonic mouse spinal cord on multi-well plates of MEAs. Primary VH cultures from embryonic day 15-16 mice were characterized by expression of choline acetyltransferase (ChAT) by immunocytochemistry...
2017: Frontiers in Cellular Neuroscience
https://www.readbyqxmd.com/read/29033283/developmental-trajectory-of-mismatch-negativity-and-visual-event-related-potentials-in-healthy-controls-implications-for-neurodevelopmental-vs-neurodegenerative-models-of-schizophrenia
#20
Cheryl M Corcoran, Anastasia Stoops, Migyung Lee, Antigona Martinez, Pejman Sehatpour, Elisa C Dias, Daniel C Javitt
Sensory processing deficits are core features of schizophrenia, reflected in impaired generation of event-related potential (ERP) measures such as auditory mismatch negativity (MMN) and visual P1. To understand the potential time course of development of deficits in schizophrenia, we obtained MMN to unattended duration, intensity and frequency deviants, and visual P1 to attended LSF stimuli, in 43 healthy individuals ages 6 to 25years (mean 17), and compared results to data from 30 adult schizophrenia patients (mean age 38)...
October 12, 2017: Schizophrenia Research
keyword
keyword
2004
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"