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https://www.readbyqxmd.com/read/29778070/high-intensity-binge-drinking-is-associated-with-alterations-in-spontaneous-neural-oscillations-in-young-adults
#1
Rifqi O Affan, Siyuan Huang, Stephen M Cruz, Lee A Holcomb, Edward Nguyen, Ksenija Marinkovic
Heavy episodic alcohol consumption (also termed binge drinking) contributes to a wide range of health and cognitive deficits, but the associated brain-based indices are poorly understood. The current study used electroencephalography (EEG) to examine spontaneous neural oscillations in young adults as a function of quantity, frequency, and the pattern of their alcohol consumption. Sixty-one young adults (23.4 ± 3.4 years of age) were assigned to binge drinking (BD) and light drinking (LD) groups that were equated on gender, race/ethnic identity, age, educational background, and family history of alcoholism...
January 8, 2018: Alcohol
https://www.readbyqxmd.com/read/29776920/determinants-of-return-at-work-of-breast-cancer-patients-results-from-the-optisoins01-french-prospective-study
#2
Alexandra Arfi, Sandrine Baffert, Anne-Laure Soilly, Cyrille Huchon, Fabien Reyal, Bernard Asselain, Souhir Neffati, Roman Rouzier, Delphine Héquet
INTRODUCTION: Return to work (RTW) after breast cancer (BC) is still a new field of research. The factors determining shorter sick leave duration of patients with BC have not been clearly identified. The aim of this study was to describe work during BC treatment and to identify factors associated with sick leave duration. MATERIALS AND METHODS: An observational, prospective, multicentre study was conducted among women with operable BC. A logbook was given to all working patients to record sociodemographic and work-related data over a 1-year period...
May 18, 2018: BMJ Open
https://www.readbyqxmd.com/read/29776002/the-chaos-of-hospitalisation-for-patients-with-critical-limb-ischaemia-approaching-major-amputation
#3
Susan Monaro, Sandra West, Jana Pinkova, Janice Gullick
AIMS AND OBJECTIVES: To illuminate the hospital experience for patients and families when major amputation has been advised for critical limb ischaemia (CLI). BACKGROUND: CLI creates significant burden to the health system and the family, particularly as the person with CLI approaches amputation. Major amputation is often offered as a late intervention for CLI in response to the marked deterioration of an ischaemic limb, and functional decline from reduced mobility, intractable pain, infection and/or toxaemia...
May 18, 2018: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/29773932/effectiveness-and-tolerability-of-therapy-with-once-weekly-exenatide-versus-basal-insulin-among-injectable-naive-patients-with-type-2-diabetes-in-a-real-world-setting-in-the-united-states
#4
Anita M Loughlin, Qing Qiao, Anthony P Nunes, Stephen M Ezzy, Laura Yochum, C Robin Clifford, Robert V Gately, David D Dore, John D Seeger
A propensity-matched cohort study compared injectable-naive patients with type 2 diabetes initiating exenatide once weekly (EQW) or basal insulin (BI), from 2012 through 2015, within a U.S. electronic health record database. A1C and weight were obtained as observed or multiply imputed values at baseline and quarterly for 1 year (Q1-Q4). Hypoglycemia and gastrointestinal symptoms were identified using diagnostic codes and clinical notes. EQW ( n = 2,008) and BI ( n = 4,016) cohorts were comparable at baseline (mean A1C and weight: EQW, 8...
May 2018: Diabetes Spectrum: a Publication of the American Diabetes Association
https://www.readbyqxmd.com/read/29772946/safety-and-effectiveness-of-apixaban-in-comparison-to-warfarin-in-patients-with-nonvalvular-atrial-fibrillation-a-propensity-matched-analysis-from-japanese-administrative-claims-data
#5
Shun Kohsaka, Jun Katada, Kumiko Saito, Yasuo Terayama
OBJECTIVE: To investigate the risk of bleeding events and stroke/systemic embolism (SE) among Japanese patients with nonvalvular atrial fibrillation (NVAF), focusing on the initial dosage of apixaban and patient age. METHODS: This retrospective cohort study used de-identified electronic health records-based claims data from 314 acute-care hospitals in Japan. NVAF patients newly initiated on warfarin or apixaban, with no prescription during the 180-day blanking period, were eligible...
May 18, 2018: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/29771617/public-support-for-gun-violence-prevention-policies-among-gun-owners-and-non-gun-owners-in-2017
#6
Colleen L Barry, Daniel W Webster, Elizabeth Stone, Cassandra K Crifasi, Jon S Vernick, Emma E McGinty
OBJECTIVES: To compare public support for 24 different gun policies between gun owners and non-gun owners in 2017. METHODS: We fielded a national public opinion survey in January 2017 using an online panel to measure US adults' support for 24 gun policies. We compared support among gun owners and non-gun owners. RESULTS: For 23 of the 24 policies examined, most respondents supported restricting or regulating gun ownership. Only 8 of 24 policies had greater than a 10-point support gap between gun owners and non-gun owners...
May 17, 2018: American Journal of Public Health
https://www.readbyqxmd.com/read/29771189/-i-m-just-trying-to-cope-for-both-of-us-challenges-and-supports-of-family-caregivers-in-participant-directed-programs
#7
Aimee Milliken, Ellen K Mahoney, Kevin J Mahoney, Kate Mignosa, Isabella Rodriguez, Catherine Cuchetti, Megumi Inoue
Recently, national attention has focused on the needs of family caregivers providing complex chronic care, noting the necessity to better understand the scope of challenges they encounter. Although a robust body of literature exists about the scope of family caregiving, little is known specifically about the experiences and perspectives of family caregivers who support participant directed (PD) participants, particularly across the caregiving trajectory. Therefore, the aim of this qualitative descriptive study was to describe what family caregivers of individuals with developmental disabilities, physical disabilities, aging, or chronic health conditions identify as the challenges they experience as complex, and their perceptions of the effectiveness and gaps in family support resources in PD...
May 17, 2018: Journal of Gerontological Social Work
https://www.readbyqxmd.com/read/29769803/gender-dysphoria-assessment-and-action-for-youth-review-of-health-care-services-and-experiences-of-trans-youth-in-manitoba
#8
Jack Heard, Amanda Morris, Nicole Kirouac, Jennifer Ducharme, Simon Trepel, Brandy Wicklow
Objectives: To describe the paediatric transgender population accessing health care through the Manitoba Gender Dysphoria Assessment and Action for Youth (GDAAY) program, and report youth's experiences accessing health care in Manitoba. Methods: Demographic, medical, surgical and mental health information was extracted from the medical records of youth referred to the GDAAY program (n=174). A 77-item online survey was conducted with a subset of those youth (n=25) to identify common health care experiences and perceptions of trans youth in Manitoba...
May 2018: Paediatrics & Child Health
https://www.readbyqxmd.com/read/29769554/long-term-extension-of-a-randomised-controlled-trial-of-probiotics-using-electronic-health-records
#9
Gareth Davies, Sue Jordan, Caroline J Brooks, Daniel Thayer, Melanie Storey, Gareth Morgan, Stephen Allen, Iveta Garaiova, Sue Plummer, Mike Gravenor
Most randomised controlled trials (RCTs) are relatively short term and, due to costs and available resources, have limited opportunity to be re-visited or extended. There is no guarantee that effects of treatments remain unchanged beyond the study. Here, we illustrate the feasibility, benefits and cost-effectiveness of enriching standard trial design with electronic follow up. We completed a 5-year electronic follow up of a RCT investigating the impact of probiotics on asthma and eczema in children born 2005-2007, with traditional fieldwork follow up to two years...
May 16, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29767683/large-outbreak-of-hepatitis-c-virus-associated-with-drug-diversion-by-a-healthcare-technician
#10
Sharon Alroy-Preis, Elizabeth R Daly, Christine Adamski, Jodie Dionne-Odom, Elizabeth A Talbot, Fengxiang Gao, Steffany J Cavallo, Katrina Hansen, Jennifer C Mahoney, Erin Metcalf, Carol Loring, Christine Bean, Jan Drobeniuc, Guo-Liang Xia, Saleem Kamili, José T Montero
Background: In May 2012, the New Hampshire (NH) Division of Public Health Services (DPHS) was notified of 4 persons with newly diagnosed hepatitis C virus (HCV) infection at hospital X. Initial investigation suggested a common link to the hospital cardiac catheterization laboratory (CCL) because the infected persons included 3 CCL patients and a CCL technician. NH DPHS initiated an investigation to determine the source and control the outbreak. Methods: NH DPHS conducted site visits, case patient and employee interviews, medical record and medication use review, and employee and patient HCV testing using enzyme immunoassay for anti-HCV, reverse-transcription polymerase chain reaction for HCV RNA, nonstructural 5B (NS5B) and hypervariable region 1 (HVR1) sequencing, and quasispecies analysis...
May 14, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29765224/statins-use-and-risk-of-new-onset-diabetes-in-hypertensive-patients-a-population-based-retrospective-cohort-study-in-yinzhou-district-ningbo-city-people-s-republic-of-china
#11
Hailong Li, Hongbo Lin, Houyu Zhao, Yang Xu, Yinchu Cheng, Peng Shen, Siyan Zhan
Background: Reports have suggested that statin use is associated with an increased incidence of type 2 diabetes mellitus (T2DM). Guidelines suggested that statins should be prescribed in hypertensive patients for primary prevention. However, there were very few studies on the risk of T2DM associated with statin use among patients with hypertension in mainland People's Republic of China. Purpose: To determine the association between statin use and new-onset diabetes mellitus among patients with hypertension in mainland People's Republic of China...
2018: Therapeutics and Clinical Risk Management
https://www.readbyqxmd.com/read/29763935/comorbidities-are-associated-with-altered-health-services-use-in-multiple-sclerosis-a-prospective-cohort-study
#12
Kyla A McKay, Ruth Ann Marrie, John D Fisk, Scott B Patten, Helen Tremlett
BACKGROUND: Persons with multiple sclerosis (MS) use health resources with greater frequency than the general population. However, little is known regarding which patient characteristics might contribute. OBJECTIVE: The study aimed to evaluate characteristics associated with healthcare use in MS patients. METHODS: Consecutive MS clinic attendees were recruited (September-November 2010), with clinical, demographic, and patient-completed questionnaires collected at 3 visits over 2 years...
May 15, 2018: Neuroepidemiology
https://www.readbyqxmd.com/read/29759096/australian-consumers-views-towards-an-environmentally-sustainable-eating-pattern
#13
Davina Mann, Lukar Thornton, David Crawford, Kylie Ball
OBJECTIVE: The present qualitative study aimed to gain an in-depth understanding of participants' attitudes, knowledge, perceived effectiveness (a person's belief that his/her behaviour can contribute to environmental preservation) and behaviours relating to a sustainable eating pattern. DESIGN: One-to-one interviews (either face-to-face or by telephone) were conducted following a structured interview schedule, audio-recorded, transcribed verbatim and analysed using inductive thematic analysis in NVivo 10...
May 15, 2018: Public Health Nutrition
https://www.readbyqxmd.com/read/29757962/the-relationship-between-shoe-fitting-and-foot-health-of-persons-with-down-syndrome-a-case-control-study
#14
César Calvo-Lobo, Ana Ramos García, Marta Elena Losa Iglesias, Daniel López-López, David Rodríguez-Sanz, Carlos Romero-Morales, Ricardo Becerro-de-Bengoa-Vallejo
Background : Down syndrome is the most common chromosomal abnormality and a cause of intellectual disability. It is also associated with orthopaedic and musculoskeletal problems of the locomotive apparatus, especially of the feet. These problems are believed to have a harmful effect on health, social functioning, and mobility. In addition, these persons generally don't have access to podiatric health services, even when their foot problems are well known, because of limited access to healthcare facilities. The goal of our research was to evaluate and compare the foot health status of study participants with and without Down syndrome and to determine whether inadequate footwear is being used with normalized reference values...
May 14, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29757869/end-of-life-care-for-patients-with-advanced-ovarian-cancer-is-aggressive-despite-hospice-intervention-a-population-based-study
#15
Jui-Kun Chiang, Chun-Shuo Hsu, Chih-Wen Lin, Yee-Hsin Kao
OBJECTIVE: To date, few studies have examined end-of-life (EOL) care and healthcare costs for patients with ovarian cancer. We evaluated the effects of hospice care on the quality of EOL care and healthcare costs for patients with ovarian cancer in the final month of life. MATERIALS AND METHODS: We conducted a population-based study and analyzed data from Taiwan's Longitudinal Health Insurance Database, which contains claims information for medical records of patients, healthcare costs, and insurance system exit dates: our proxy for death between 1997 and 2011...
May 11, 2018: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/29756800/cognitive-complaints-mediate-the-effect-of-cognition-on-emotional-stability-across-12-years-in-old-age
#16
Damaris Aschwanden, Matthias Kliegel, Mathias Allemand
Previous research supports a positive relationship between cognition and emotional stability, although findings regarding healthy older adults are inconsistent. Additionally, little is known about the mechanisms that underlie this association. Thus, the present study investigated the mediating effect of cognitive complaints on the bidirectional longitudinal association between cognition and emotional stability in old age. The study sample consisted of 500 older individuals (M age = 62.97 years, SD = 0.91, range = 60-64 years; 52% male) from the Interdisciplinary Longitudinal Study on Adult Development...
May 2018: Psychology and Aging
https://www.readbyqxmd.com/read/29756684/a-prospective-bottom-up-study-of-the-costs-of-faecal-incontinence-in-ambulatory-patients
#17
Vicki Patton, Katrina Parkin, Kate H Moore
BACKGROUND AND AIM: The few studies that have examined direct costs of faecal incontinence are limited in that they employed retrospective databases, postal surveys, and focused upon institutionalised patients or post partum women. The aim of the current study was to identify the direct pre-treatment costs of faecal incontinence expended by a range of home dwelling patients and identify relationships between costs and severity of incontinence. METHODS: Consecutive patients attending an outpatient clinic for treatment of faecal incontinence were interviewed using a questionnaire, modeled on the Dowel Bryant Incontinence Cost Index...
May 14, 2018: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/29753161/engagement-with-inspire-an-online-program-for-hematopoietic-cell-transplantation-survivors
#18
Karen L Syrjala, Marie-Laure Crouch, Wendy M Leisenring, Mary E D Flowers, Samantha B Artherholt, Allison Stover Fiscalini, Eleni Romano, Joan M Romano, Paul J Martin, Jean C Yi
PURPOSE: In a secondary analysis of a randomized controlled trial (RCT), we examined engagement with INSPIRE, a personalized online program for hematopoietic cell transplantation (HCT) survivors that focused on cancer-related distress, depression, fatigue, and health care needs. METHODS: We approached all adult, 3-18 year HCT survivors treated for hematologic malignancy, without relapse or second cancer in the previous 2 years, for participation in an RCT with either immediate or delayed access to INSPIRE...
May 9, 2018: Biology of Blood and Marrow Transplantation
https://www.readbyqxmd.com/read/29752159/predictors-of-falls-and-fractures-leading-to-hospitalization-in-people-with-dementia-a-representative-cohort-study
#19
Shalini Sharma, Christoph Mueller, Robert Stewart, Nicola Veronese, Davy Vancampfort, Ai Koyanagi, Sarah E Lamb, Gayan Perera, Brendon Stubbs
OBJECTIVES: Investigate predictors of falls and fractures leading to hospitalization in a large cohort of people with dementia. DESIGN: A retrospective cohort study. SETTING AND PARTICIPANTS: People with diagnosed dementia between January 2007 and March 2013, aged >65 years, were assembled using data from the Maudsley Biomedical Research Centre Case Register, from 4 boroughs in London serving a population of 1.3 million people. MEASURES: Falls and/or fractures leading to hospitalization were ascertained from linked national records...
May 2, 2018: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/29750933/regional-thoracic-surgery-quality-collaboration-formation-providence-thoracic-surgery-initiative
#20
John R Handy, Kimberly Costas, Robert McKenna, Steven Nisco, Raymond Schaerf, Kenton Stephens, Eric Vallières, Kasia Konieczny, Roshanthi Weerasinghe, Mansen Wang, Katherine Lothrop, Cathy Betzer
BACKGROUND: Surgery quality initiatives improve clinical outcomes in cardiac and general surgery. No mature thoracic surgery (TS) regional effort has been described. METHODS: An intramural grant funded the Thoracic Surgery Initiative (TSI). Using professional organization, site specific administrative and clinical databases, surgeons performing TS across a large western health system were identified. Participants were recruited through stakeholder surveys, personal contact and meetings...
May 8, 2018: Annals of Thoracic Surgery
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