Shatha M Alobaid, Rahaf M Alshahrani, Asma S Alonazi, Nawal M Alrasheed, Maha A Alamin, Tahani K Alshammari, Anfal F Bin Dayel, Doaa M Elnagar, Rana R Alotaibi, Lama A Almuthnabi, Dalia H Almasud, Shahad E Al-Ammar, Shahad O Almadhi, Reema A Almalke, Nouf T Aldamri, Hanan K Alghibiwi, Dalal A Alkhelb, Nouf M Alrasheed
One of the possible candidates for the treatment of diabetic cardiomyopathy is liraglutide, a glucagon-like peptide-1 receptor (GLP1R) agonist. In this study, the impacts of liraglutide on the integrin-linked kinase (ILK)-related PI3K/AKT axis in rats with type 2 diabetes induced via streptozotocin were examined. Twenty-four Wistar albino rats were distributed in four different groups, and a high-fat diet and streptozotocin were used to induce type 2 in two groups. Rats in the untreated control groups were administered 0...
March 15, 2024: Pharmaceuticals